A single amino acid substitution within the matrix protein of a type D retrovirus converts its morphogenesis to that of a type C retrovirus

Rhee, Sung S.; Hunter, Eric

doi:10.1016/0092-8674(90)90289-q

Cited by 160T-cell and Retrovirus StudiesHIV Research and TreatmentCellular transport and secretion

A single amino acid substitution within the matrix protein of a type D retrovirus converts its morphogenesis to that of a type C retrovirus

Rhee, Sung S., Hunter, Eric·1990·Cell

DOI 10.1016/0092-8674(90)90289-q

Open this paper in CoChat — free account

Abstract

Two different morphogenic processes of retroviral capsid assembly have been observed: the capsid is either assembled at the plasma membrane during the budding process (type C), or preassembled within the cytoplasm (types B and D). We describe here a gag mutant of Mason-Pfizer monkey virus, a type D retrovirus, in which a tryptophan substituted for an arginine in the matrix protein results in efficient assembly of capsids at the plasma membrane through a morphogenic process similar to that of type C retroviruses. We conclude that a type D retrovirus Gag polyprotein contains an additional, dominant signal that prevents immediate transport of precursors from the site of biosynthesis to the plasma membrane. Instead, they are directed to and retained at a cytoplasmic site where a concentration sufficient for self-assembly into capsids occurs. Thus, capsid assembly processes for different retroviruses appear to differ only in the intracellular site to which capsid precursors are directed.

Integrity signals

Registry

Crossref · 10.1016/0092-8674(90)90289-q

Cites

62 of 62 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

In RSV, MA and envelope chemically cross-link, while mutations in MPMV MA lead to inefficient envelope incorporation and postbudding cleavage of the envelope.
“For example, in RSV, MA and envelope chemically cross-link, while mutations in MPMV MA lead to inefficient envelope incorporation and postbudding cleavage of the envelope”
From Beyond reverse transcription: molecular mechanisms and emerging paradigms in retroviral replication (2026) · cites this paper as Rhee and Hunter 1990
The MA domain of Gag in other retroviruses is involved in envelope incorporation.
“The MA domain of Gag in other retroviruses has also been shown to be involved in envelope incorporation.”
From Beyond reverse transcription: molecular mechanisms and emerging paradigms in retroviral replication (2026) · cites this paper as Rhee and Hunter 1990
Amino acid substitutions in the MA sequence of MPMV, MMTV, JSRV, and spumaviruses relocate their assembly from cytoplasm to plasma membrane, a major shift from type D to type C pattern.
“The critical role of Gag in virion assembly has been clearly demonstrated by amino acid substitutions(s) in the MA sequence of MPMV, MMTV, JSRV, and spumaviruses, resulting in the relocation of their assembly from cytoplasm to the plasma membrane—a major shift from a type D to a type C pattern”
From Beyond reverse transcription: molecular mechanisms and emerging paradigms in retroviral replication (2026) · cites this paper as Rhee and Hunter 1990

DNA sequencing with chain-terminating inhibitors
Sanger, F., Nicklen, S., & Coulson, A. R. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.12.5463 · Cited by 68,572 · see citing works
A new technique for the assay of infectivity of human adenovirus 5 DNA
Graham, F. L., & van der Eb, A. J. (1973) · Virology · doi:10.1016/0042-6822(73)90341-3 · Cited by 9,734 · see citing works
High-Efficiency Transformation of Mammalian Cells by Plasmid DNA
Chen, C., & Okayama, H. (1987) · Molecular and Cellular Biology · doi:10.1128/mcb.7.8.2745 · Cited by 5,374 · see citing works
Intracellular Aspects of the Process of Protein Synthesis
Palade, G. E. (1975) · Science · doi:10.1126/science.1096303 · Cited by 3,583 · see citing works
Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.
Blobel, G., & Dobberstein, B. (1975) · The Journal of Cell Biology · doi:10.1083/jcb.67.3.835 · Cited by 3,014 · see citing works
A short amino acid sequence able to specify nuclear location
Kalderon, D., Roberts, B., Richardson, W. D., & Smith, A. E. (1984) · Cell · doi:10.1016/0092-8674(84)90457-4 · Cited by 2,511 · see citing works
Intracellular protein topogenesis
Blobel, G. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.3.1496 · Cited by 1,393 · see citing works
Sequence requirements for nuclear location of simian virus 40 large-T antigen
Kalderon, D., Richardson, W. D., Markham, A. F., & Smith, A. E. (1984) · Nature · doi:10.1038/311033a0 · Cited by 1,286 · see citing works
Homologous plant and bacterial proteins chaperone oligomeric protein assembly
Hemmingsen, S. M., Woolford, C. A., van der Vies, S. M., Tilly, K., Dennis, D. T., Georgopoulos, C. P., Hendrix, R. W., & Ellis, R. J. (1988) · Nature · doi:10.1038/333330a0 · Cited by 1,283 · see citing works
Three-Dimensional Structure of Poliovirus at 2.9 Å Resolution
Hogle, J. M., Chow, M., & Filman, D. J. (1985) · Science · doi:10.1126/science.2994218 · Cited by 1,262 · see citing works
Nucleotide sequence of Moloney murine leukaemia virus
Shinnick, T. M., Lerner, R. A., & Sutcliffe, J. G. (1981) · Nature · doi:10.1038/293543a0 · Cited by 1,057 · see citing works
Oligonucleotide-Directed Mutagenesis: A Simple Method Using Two Oligonucleotide Primers and a Single-Stranded DNA Template
Zoller, M. J., & Smith, M. J. (1984) · DNA · doi:10.1089/dna.1.1984.3.479 · Cited by 906 · see citing works
Mechanisms for the incorporation of proteins in membranes and organelles.
Sabatini, D. D., Kreibich, G., Morimoto, T., & Adesnik, M. (1982) · The Journal of Cell Biology · doi:10.1083/jcb.92.1.1 · Cited by 863 · see citing works
Fine structure of human immunodeficiency virus (HIV) and immunolocalization of structural proteins
Gelderblom, H. R., Hausmann, E. H. S., Özel, M., Pauli, G., & Koch, M. A. (1987) · Virology · doi:10.1016/0042-6822(87)90449-1 · Cited by 521 · see citing works
Myristylation of picornavirus capsid protein VP4 and its structural significance
Chow, M., Newman, J. F. E., Filman, D. J., Hogle, J. M., Rowlands, D. J., & Brown, F. (1987) · Nature · doi:10.1038/327482a0 · Cited by 477 · see citing works
The Atomic Structure of Mengo Virus at 3.0 Å Resolution
Luo, M., Vriend, G., Kamer, G., Minor, I., Arnold, E., Rossmann, M. G., Boege, U., Scraba, D. G., Duke, G. M., & Palmenberg, A. C. (1987) · Science · doi:10.1126/science.3026048 · Cited by 357 · see citing works
Nucleotide sequence of Mason-Pfizer monkey virus: An immunosuppressive D-type retrovirus
Sonigo, P. (1986) · Cell · doi:10.1016/0092-8674(86)90323-5 · Cited by 339 · see citing works
Characterization of the yeast HSP60 gene coding for a mitochondrial assembly factor
Reading, D. S., Hallberg, R. L., & Myers, A. M. (1989) · Nature · doi:10.1038/337655a0 · Cited by 336 · see citing works
The detection and study of tumor viruses with the electron microscope.
Bernhard, W. (1960) · PubMed · Cited by 300 · see citing works
Electron microscopy of tumor cells and tumor viruses; a review.
Bernhard, W. (1958) · PubMed · Cited by 299 · see citing works
Myristylation site in Pr65gag is essential for virus particle formation by Moloney murine leukemia virus.
Rein, A., McClure, M. R., Rice, N. R., Luftig, R. B., & Schultz, A. M. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.19.7246 · Cited by 297 · see citing works
An Improved Technique for Obtaining Enhanced Infectivity with Herpes Simplex Virus Type 1 DNA
Stow, N. D., & Wilkie, N. M. (1976) · Journal of General Virology · doi:10.1099/0022-1317-33-3-447 · Cited by 286 · see citing works
Local mutagenesis: a method for generating viral mutants with base substitutions in preselected regions of the viral genome.
Shortle, D., & Nathans, D. (1978) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.75.5.2170 · Cited by 278 · see citing works
Coming in from the cold
Pelham, H. R. B. (1988) · Nature · doi:10.1038/332776a0 · Cited by 275 · see citing works
Complete nucleotide sequence of a milk-transmitted mouse mammary tumor virus: two frameshift suppression events are required for translation of gag and pol
Moore, R., Dixon, M., Smith, R., Peters, G., & Dickson, C. (1987) · Journal of Virology · doi:10.1128/jvi.61.2.480-490.1987 · Cited by 256 · see citing works
Three-Dimensional Structure of the Adenovirus Major Coat Protein Hexon
Roberts, M. M., White, J. L., Grütter, M. G., & Burnett, R. M. (1986) · Science · doi:10.1126/science.3704642 · Cited by 247 · see citing works
Myristylation is required for intracellular transport but not for assembly of D-type retrovirus capsids
Rhee, S. S., & Hunter, E. (1987) · Journal of Virology · doi:10.1128/jvi.61.4.1045-1053.1987 · Cited by 236 · see citing works
Self-citation
The use of nuclear‐encoded sequences to direct the light‐regulated synthesis and transport of a foreign protein into plant chloroplasts
Schreier, P. H., Seftor, E. A., Schell, J. S., & Bohnert, H. J. (1985) · The EMBO Journal · doi:10.1002/j.1460-2075.1985.tb02312.x · Cited by 230 · see citing works
The GAG precursor of simian immunodeficiency virus assembles into virus‐like particles.
Delchambre, M., Gheysen, D., Thinès, D., Thiriart, C., Jacobs, E., Verdin, E. M., Horth, M., Burny, A., & Bex, F. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb08405.x · Cited by 224 · see citing works
An electron microscopic study of moderate and virulent virus-cell interactions of the parainfluenza virus SV5
Compans, R. W., Holmes, K. V., Dales, S., & Choppin, P. W. (1966) · Virology · doi:10.1016/0042-6822(66)90119-x · Cited by 206 · see citing works
Rous sarcoma virus transforming protein lacking myristic acid phosphorylates known polypeptide substrates without inducing transformation
Kamps, M. P., Buss, J. E., & Sefton, B. M. (1986) · Cell · doi:10.1016/0092-8674(86)90542-8 · Cited by 205 · see citing works
An N-terminal peptide from p60src can direct myristylation and plasma membrane localization when fused to heterologous proteins
Pellman, D. S., Garber, E. A., Cross, F. R., & Hanafusa, H. (1985) · Nature · doi:10.1038/314374a0 · Cited by 203 · see citing works
A 70‐kd protein of the yeast mitochondrial outer membrane is targeted and anchored via its extreme amino terminus.
Hase, T., Müller, U., Riezman, H., & Schatz, G. (1984) · The EMBO Journal · doi:10.1002/j.1460-2075.1984.tb02274.x · Cited by 196 · see citing works
Implications of the picornavirus capsid structure for polyprotein processing.
Arnold, E., Luo, M., Vriend, G., Rossmann, M. G., Palmenberg, A. C., Parks, G. D., Nicklin, M. J. H., & Wimmer, E. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.1.21 · Cited by 188 · see citing works
The absence of myristic acid decreases membrane binding of p60src but does not affect tyrosine protein kinase activity
Buss, J. E., Kamps, M. P., Gould, K. L., & Sefton, B. M. (1986) · Journal of Virology · doi:10.1128/jvi.58.2.468-474.1986 · Cited by 170 · see citing works
Transit of pp60v-src to the plasma membrane.
Courtneidge, S. A., & Bishop, J. M. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.23.7117 · Cited by 165 · see citing works
Properties of mouse leukemia viruses
Nermut, M. V., Frank, H., & Schäfer, W. (1972) · Virology · doi:10.1016/0042-6822(72)90487-4 · Cited by 161 · see citing works
Interaction Between the Rous Sarcoma Virus Transforming Protein and Two Cellular Phosphoproteins: Analysis of the Turnover and Distribution of This Complex
Brugge, J. S., Yonemoto, W. M., & Darrow, D. (1983) · Molecular and Cellular Biology · doi:10.1128/mcb.3.1.9-19.1983 · Cited by 159 · see citing works
Protein Transfer and Organelle Biogenesis
(1988) · Elsevier eBooks · doi:10.1016/b978-0-12-203460-2.x5001-x · Cited by 144 · see citing works
Specific and saturable binding of pp60v-src to plasma membranes: Evidence for a myristyl-src receptor
Resh, M. D. (1989) · Cell · doi:10.1016/0092-8674(89)90842-8 · Cited by 129 · see citing works
Isolation of Defective Mutant of Avian Sarcoma Virus
Kawai, S., & Hanafusa, H. (1973) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.70.12.3493 · Cited by 115 · see citing works
Type D primate retroviruses: a review.
Fine, D. L., & Schochetman, G. (1978) · PubMed · Cited by 113 · see citing works
The structure of the adenovirus capsid
Burnett, R. M. (1985) · Journal of Molecular Biology · doi:10.1016/0022-2836(85)90187-1 · Cited by 111 · see citing works
Mutations of the Rous sarcoma virus env gene that affect the transport and subcellular location of the glycoprotein products.
Wills, J. W., Srinivas, R. V., & Hunter, E. (1984) · The Journal of Cell Biology · doi:10.1083/jcb.99.6.2011 · Cited by 105 · see citing works
Self-citation
Structural Studies of Avian Myeloblastosis Virus: Comparison of Polypeptides in Virion and Core Component by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis
Stromberg, K., Hurley, N. E., Davis, N., Rueckert, R. R., & Fleissner, E. (1974) · Journal of Virology · doi:10.1128/jvi.13.2.513-528.1974 · Cited by 101 · see citing works
Common Precursor for Rauscher Leukemia Virus gp69/71, p15(E), and p12(E)
Karshin, W. L., Arcement, L. J., Naso, R. B., & Arlinghaus, R. B. (1977) · Journal of Virology · doi:10.1128/jvi.23.3.787-798.1977 · Cited by 99 · see citing works
Role of myristoylation of poliovirus capsid protein VP4 as determined by site‐directed mutagenesis of its N‐terminal sequence.
Marc, D., Drugeon, G., Haenni, A., Girard, M. P., & van der Werf, S. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb08406.x · Cited by 98 · see citing works
Identification of the spike proteins of Rous sarcoma virus
Rifkin, D. B., & Compans, R. W. (1971) · Virology · doi:10.1016/0042-6822(71)90049-3 · Cited by 97 · see citing works
Unmyristylated Moloney murine leukemia virus Pr65gag is excluded from virus assembly and maturation events
Schultz, A. M., & Rein, A. (1989) · Journal of Virology · doi:10.1128/jvi.63.5.2370-2373.1989 · Cited by 96 · see citing works
Processing of p60v-src to its myristylated membrane-bound form.
Garber, E. A., Cross, F. R., & Hanafusa, H. (1985) · Molecular and Cellular Biology · doi:10.1128/mcb.5.10.2781 · Cited by 93 · see citing works
Preassembled capsids of type D retroviruses contain a signal sufficient for targeting specifically to the plasma membrane
Rhee, S. S., Hui, H., & Hunter, E. (1990) · Journal of Virology · doi:10.1128/jvi.64.8.3844-3852.1990 · Cited by 75 · see citing works
Self-citation
Polypeptides of Mason-Pfizer monkey virus I. Synthesis and processing of the gag-gene products
Bradac, J. A., & Hunter, E. (1984) · Virology · doi:10.1016/0042-6822(84)90350-7 · Cited by 73 · see citing works
Self-citation
The Classification and Nomenclature of Viruses
Fenner, F. J. (1975) · Intervirology · doi:10.1159/000149448 · Cited by 69 · see citing works
Structural role of the matrix protein of type D retroviruses in gag polyprotein stability and capsid assembly
Rhee, S. S., & Hunter, E. (1990) · Journal of Virology · doi:10.1128/jvi.64.9.4383-4389.1990 · Cited by 62 · see citing works
Self-citation
Purification and N-terminal amino acid sequence comparisons of structural proteins from retrovirus-D/Washington and Mason-Pfizer monkey virus
Henderson, L. E., Sowder, R. C., II, Smythers, G. W., Benveniste, R. E., & Oroszlan, S. I. (1985) · Journal of Virology · doi:10.1128/jvi.55.3.778-787.1985 · Cited by 59 · see citing works
A rapid and efficient method for region‐ and strand‐specific mutagenesis of cloned DNA.
Everett, R. D., & Chambon, P. (1982) · The EMBO Journal · doi:10.1002/j.1460-2075.1982.tb01187.x · Cited by 37 · see citing works
Polypeptides of Mason-Pfizer monkey virus. III. translational order of proteins on the gag and env gene specified precursor polypeptides
Bradac, J. A., & Hunter, E. (1986) · Virology · doi:10.1016/0042-6822(86)90314-4 · Cited by 22 · see citing works
Self-citation
Molecular cloning of the Mason-Pfizer monkey virus genome: Characterization and cloning of subgenomic fragments
Barker, C. S., Wills, J. W., Bradac, J. A., & Hunter, E. (1985) · Virology · doi:10.1016/0042-6822(85)90331-9 · Cited by 22 · see citing works
Self-citation
Synthesis and processing of viral glycoproteins in two nonconditional mutants of Rous sarcoma virus
Linial, M., Fenno, J. C., Burnette, W. N., & Rohrschneider, L. R. (1980) · Journal of Virology · doi:10.1128/jvi.36.1.280-290.1980 · Cited by 21 · see citing works
Nonconditional replication mutants of type C and type D retroviruses defective in gag gene-coded polyprotein post-translational processing
Sacks, T. L., Devare, S. G., Blennerhassett, G. T., & Stephenson, J. R. (1978) · Virology · doi:10.1016/0042-6822(78)90383-5 · Cited by 21 · see citing works
Polypeptides of mason-pfizer monkey virus II. Synthesis and processing of the env gene products
Bradac, J. A., & Hunter, E. (1986) · Virology · doi:10.1016/0042-6822(86)90313-2 · Cited by 12 · see citing works
Self-citation
Membrane Insertion and Transport of Viral Glycoproteins: A Mutational Analysis
Hunter, E. (1988) · Elsevier eBooks · doi:10.1016/b978-0-12-203460-2.50007-x · Cited by 11 · see citing works
Self-citation

Flagged first, then by citations

5 of the 67 references couldn’t be matched to a known paper.

Sorted by citations

HIV-1 Gag proteins: diverse functions in the virus life cycle
Freed, E. O. (1998) · Virology · doi:10.1006/viro.1998.9398 · Cited by 717 · see citing works
Identification of a membrane-binding domain within the amino-terminal region of human immunodeficiency virus type 1 Gag protein which interacts with acidic phospholipids
Zhou, W., Parent, L. J., Wills, J. W., & Resh, M. D. (1994) · Journal of Virology · doi:10.1128/jvi.68.4.2556-2569.1994 · Cited by 529 · see citing works
Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis
Perron, H., Garson, J. A., Bedin, F., Besème, F., Paranhos‐Baccalà, G., Komurian-Pradel, F., Mallet, F., Tuke, P. W., Voisset, C., Blond, J.-L., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.14.7583 · Cited by 484 · see citing works
Virus Maturation by Budding
Garoff, H., Hewson, R., & Opstelten, D.-J. E. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.4.1171-1190.1998 · Cited by 359 · see citing works
Domains of the human immunodeficiency virus type 1 matrix and gp41 cytoplasmic tail required for envelope incorporation into virions
Freed, E., & Martin, M. (1996) · Journal of Virology · doi:10.1128/jvi.70.1.341-351.1996 · Cited by 382 · see citing works
The matrix protein of human immunodeficiency virus type 1 is required for incorporation of viral envelope protein into mature virions
Yu, X., Yuan, X., Matsuda, Z., Lee, T. H., & Essex, M. (1992) · Journal of Virology · doi:10.1128/jvi.66.8.4966-4971.1992 · Cited by 319 · see citing works
Virion incorporation of envelope glycoproteins with long but not short cytoplasmic tails is blocked by specific, single amino acid substitutions in the human immunodeficiency virus type 1 matrix
Freed, E., & Martin, M. (1995) · Journal of Virology · doi:10.1128/jvi.69.3.1984-1989.1995 · Cited by 344 · see citing works
Reconstitution of an Infectious Human Endogenous Retrovirus
Lee, Y. N., & Bieniasz, P. D. (2007) · PLoS Pathogens · doi:10.1371/journal.ppat.0030010 · Cited by 311 · see citing works
Single amino acid changes in the human immunodeficiency virus type 1 matrix protein block virus particle production
Freed, E. O., Orenstein, J. M., Buckler-White, A. J., & Martin, M. A. (1994) · Journal of Virology · doi:10.1128/jvi.68.8.5311-5320.1994 · Cited by 291 · see citing works
Role of the matrix protein in the virion association of the human immunodeficiency virus type 1 envelope glycoprotein
Dorfman, T., Mammano, F., Haseltine, W. A., & Göttlinger, H. G. (1994) · Journal of Virology · doi:10.1128/jvi.68.3.1689-1696.1994 · Cited by 288 · see citing works
Identification of human immunodeficiency virus type 1 Gag protein domains essential to membrane binding and particle assembly
Spearman, P. W., Wang, J. J., Heyden, N. V., & Ratner, L. (1994) · Journal of Virology · doi:10.1128/jvi.68.5.3232-3242.1994 · Cited by 245 · see citing works
Role of the Gag Matrix Domain in Targeting Human Immunodeficiency Virus Type 1 Assembly
Ono, A., Orenstein, J. M., & Freed, E. O. (2000) · Journal of Virology · doi:10.1128/jvi.74.6.2855-2866.2000 · Cited by 239 · see citing works
Mutations in the N-terminal region of human immunodeficiency virus type 1 matrix protein block intracellular transport of the Gag precursor
Yuan, X., Yu, X., Lee, T. H., & Essex, M. (1993) · Journal of Virology · doi:10.1128/jvi.67.11.6387-6394.1993 · Cited by 240 · see citing works
Endogenous retroviruses
Stocking, C., & Kozak, C. A. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8497-0 · Cited by 233 · see citing works
The Cell Biology of HIV-1 Virion Genesis
Bieniasz, P. D. (2009) · Cell Host & Microbe · doi:10.1016/j.chom.2009.05.015 · Cited by 215 · see citing works
A fast method to predict protein interaction sites from sequences
Gallet, X., Charloteaux, B., Thomas, A., & Brasseur, R. (2000) · Journal of Molecular Biology · doi:10.1006/jmbi.2000.4092 · Cited by 212 · see citing works
A large deletion in the matrix domain of the human immunodeficiency virus gag gene redirects virus particle assembly from the plasma membrane to the endoplasmic reticulum
Fäcke, M., Janetzko, A., Shoeman, R. L., & Kräusslich, H. G. (1993) · Journal of Virology · doi:10.1128/jvi.67.8.4972-4980.1993 · Cited by 198 · see citing works
In Vitro Assembly Properties of Purified Bacterially Expressed Capsid Proteins of Human Immunodeficiency Virus
Gross, I., Hohenberg, H., & Kräusslich, H. (1997) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1997.t01-1-00592.x · Cited by 198 · see citing works
Supramolecular organization of immature and mature murine leukemia virus revealed by electron cryo-microscopy: Implications for retroviral assembly mechanisms
Yeager, M., Wilson-Kubalek, E. M., Weiner, S. G., Brown, P. O., & Rein, A. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.13.7299 · Cited by 189 · see citing works
N-Terminal Extension of Human Immunodeficiency Virus Capsid Protein Converts the In Vitro Assembly Phenotype from Tubular to Spherical Particles
Gross, I., Hohenberg, H., Huckhagel, C., & Kräusslich, H. (1998) · Journal of Virology · doi:10.1128/jvi.72.6.4798-4810.1998 · Cited by 173 · see citing works
Structure and Classification of Retroviruses
Coffin, J. M. (1992) · Springer eBooks · doi:10.1007/978-1-4615-3372-6_2 · Cited by 164 · see citing works
Rescue of human immunodeficiency virus type 1 matrix protein mutants by envelope glycoproteins with short cytoplasmic domains
Mammano, F., Kondo, E., Sodroski, J., Bukovský, A., & Göttlinger, H. G. (1995) · Journal of Virology · doi:10.1128/jvi.69.6.3824-3830.1995 · Cited by 157 · see citing works
Gene therapy for cancer
Gutierrez, A. A., Lemoine, N. R., & Sikora, K. (1992) · The Lancet · doi:10.1016/0140-6736(92)90606-4 · Cited by 157 · see citing works
A Proline-Rich Motif (PPPY) in the Gag Polyprotein of Mason-Pfizer Monkey Virus Plays a Maturation-Independent Role in Virion Release
Yasuda, J., & Hunter, E. (1998) · Journal of Virology · doi:10.1128/jvi.72.5.4095-4103.1998 · Cited by 158 · see citing works
Self-citation
In vitro assembly of virus-like particles with Rous sarcoma virus Gag deletion mutants: identification of the p10 domain as a morphological determinant in the formation of spherical particles
Campbell, S., & Vogt, V. (1997) · Journal of Virology · doi:10.1128/jvi.71.6.4425-4435.1997 · Cited by 162 · see citing works
Retroviral mRNA nuclear export elements regulate protein function and virion assembly
Swanson, C. M., Puffer, B. A., Ahmad, K. M., Doms, R. W., & Malim, M. H. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600270 · Cited by 141 · see citing works
The regulation of primate immunodeficiency virus infectivity by Vif is cell species restricted: a role for Vif in determining virus host range and cross‐species transmission
Simon, J. H., Miller, D. L., Fouchier, R. A. M., Soares, M. A., Peden, K., & Malim, M. H. (1998) · The EMBO Journal · doi:10.1093/emboj/17.5.1259 · Cited by 140 · see citing works
Linker insertion mutations in the human immunodeficiency virus type 1 gag gene: effects on virion particle assembly, release, and infectivity
Reicin, A., Paik, S., Berkowitz, R., Luban, J., Lowy, I., & Goff, S. (1995) · Journal of Virology · doi:10.1128/jvi.69.2.642-650.1995 · Cited by 155 · see citing works
Functional chimeras of the Rous sarcoma virus and human immunodeficiency virus gag proteins
Bennett, R. P., Nelle, T. D., & Wills, J. W. (1993) · Journal of Virology · doi:10.1128/jvi.67.11.6487-6498.1993 · Cited by 130 · see citing works
A Multistep, ATP-dependent Pathway for Assembly of Human Immunodeficiency Virus Capsids in a Cell-free System
Lingappa, J. R., Hill, R. L., Wong, M. L., & Hegde, R. S. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.136.3.567 · Cited by 118 · see citing works
M‐PMV Capsid Transport Is Mediated by Env/Gag Interactions at the Pericentriolar Recycling Endosome
Sfakianos, J. N., & Hunter, E. (2003) · Traffic · doi:10.1034/j.1600-0854.2003.00126.x · Cited by 111 · see citing works
Self-citation
The M-PMV cytoplasmic targeting-retention signal directs nascent Gag polypeptides to a pericentriolar region of the cell
Sfakianos, J. N., LaCasse, R. A., & Hunter, E. (2003) · Traffic · doi:10.1034/j.1600-0854.2003.00125.x · Cited by 110 · see citing works
Self-citation
Importance of Basic Residues in the Nucleocapsid Sequence for Retrovirus Gag Assembly and Complementation Rescue
Bowzard, J. B., Bennett, R., Krishna, N. K., Ernst, S. M., Rein, A., & Wills, J. (1998) · Journal of Virology · doi:10.1128/jvi.72.11.9034-9044.1998 · Cited by 119 · see citing works
Specificity and sequence requirements for interactions between various retroviral Gag proteins
Franke, E. K., Yuan, H. E., Bossolt, K. L., Goff, S. P., & Luban, J. (1994) · Journal of Virology · doi:10.1128/jvi.68.8.5300-5305.1994 · Cited by 109 · see citing works
Foamy Virus Biology and Its Application for Vector Development
Lindemann, D., & Rethwilm, A. (2011) · Viruses · doi:10.3390/v3050561 · Cited by 97 · see citing works
Amino acid substitutions within the matrix protein of type D retroviruses affect assembly, transport and membrane association of a capsid
Rhee, S. S., & Hunter, E. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07980.x · Cited by 92 · see citing works
Self-citation
The C terminus of human immunodeficiency virus type 1 matrix protein is involved in early steps of the virus life cycle
Yu, X., Yu, Q., Lee, T. H., & Essex, M. (1992) · Journal of Virology · doi:10.1128/jvi.66.9.5667-5670.1992 · Cited by 88 · see citing works
Characterization of the genome of feline foamy virus and its proteins shows distinct features different from those of primate spumaviruses
Winkler, I., Bodem, J., Haas, L., Zemba, M., Delius, H., Flower, R., Flügel, R. M., & Löchelt, M. (1997) · Journal of Virology · doi:10.1128/jvi.71.9.6727-6741.1997 · Cited by 87 · see citing works
Efficient in vivo and in vitro assembly of retroviral capsids from Gag precursor proteins expressed in bacteria
Klikova, M., Rhee, S. S., Hunter, E., & Ruml, T. (1995) · Journal of Virology · doi:10.1128/jvi.69.2.1093-1098.1995 · Cited by 85 · see citing works
Self-citation
The transdominant endogenous retrovirus enJS56A1 associates with and blocks intracellular trafficking of Jaagsiekte sheep retrovirus Gag
Murcia, P. R., Arnaud, F., & Palmarini, M. (2007) · Journal of Virology · doi:10.1128/jvi.01859-06 · Cited by 84 · see citing works
Efficient particle formation can occur if the matrix domain of human immunodeficiency virus type 1 Gag is substituted by a myristylation signal
Lee, P. P., & Linial, M. (1994) · Journal of Virology · doi:10.1128/jvi.68.10.6644-6654.1994 · Cited by 89 · see citing works
Expression and extracellular release of human immunodeficiency virus type 1 Gag precursors by recombinant baculovirus-infected cells
Royer, M., Hong, S. S., Gay, B., Cérutti, M., & Boulanger, P. A. (1992) · Journal of Virology · doi:10.1128/jvi.66.5.3230-3235.1992 · Cited by 81 · see citing works
Phenotypic characterization of insertion mutants of the human immunodeficiency virus type 1 Gag precursor expressed in recombinant baculovirus-infected cells
Chazal, N., Carrière, C., Gay, B., & Boulanger, P. A. (1994) · Journal of Virology · doi:10.1128/jvi.68.1.111-122.1994 · Cited by 81 · see citing works
Roles of Matrix, p2, and N-Terminal Myristoylation in Human Immunodeficiency Virus Type 1 Gag Assembly
Morikawa, Y., HOCKLEY, D. J., Nermut, M. V., & Jones, I. M. (2000) · Journal of Virology · doi:10.1128/jvi.74.1.16-23.2000 · Cited by 80 · see citing works
Incorporation of homologous and heterologous proteins into the envelope of Moloney murine leukemia virus
Suomalainen, M., & Garoff, H. (1994) · Journal of Virology · doi:10.1128/jvi.68.8.4879-4889.1994 · Cited by 77 · see citing works
A chimeric avian retrovirus containing the influenza virus hemagglutinin gene has an expanded host range
Dong, J., Roth, M. G., & Hunter, E. (1992) · Journal of Virology · doi:10.1128/jvi.66.12.7374-7382.1992 · Cited by 77 · see citing works
Self-citation
The Roles of Pol and Env in the Assembly Pathway of Human Foamy Virus
Baldwin, D. N., & Linial, M. (1998) · Journal of Virology · doi:10.1128/jvi.72.5.3658-3665.1998 · Cited by 94 · see citing works
Identification and Characterization of Virus Assembly Intermediate Complexes in HIV-1-Infected CD4+T Cells
Lee, Y. M., & Yu, X.-F. (1998) · Virology · doi:10.1006/viro.1998.9064 · Cited by 74 · see citing works
Mechanisms of Retrovirus Replication
Luciw, P. A., & Leung, N. J. (1992) · Springer eBooks · doi:10.1007/978-1-4615-3372-6_5 · Cited by 74 · see citing works
Synthesis and assembly of retrovirus Gag precursors into immature capsids in vitro
Sakalian, M., Parker, S. D., Weldon, R. A., & Hunter, E. (1996) · Journal of Virology · doi:10.1128/jvi.70.6.3706-3715.1996 · Cited by 74 · see citing works
Self-citation
Interference with the production of infectious viral particles and bimodal inhibition of replication are broadly conserved antiviral properties of IFITMs
Tartour, K., Nguyen, X.-N., Appourchaux, R., Assil, S., Barateau, V., Bloyet, L.-M., Burlaud Gaillard, J., Confort, M.-P., Escudero-Perez, B., Gruffat, H., et al. (2017) · PLOS Pathogens · doi:10.1371/journal.ppat.1006610 · Cited by 69 · see citing works
The molecular basis of HIV capsid assembly—five years of progress
Adamson, C. S., & Jones, I. M. (2004) · Reviews in Medical Virology · doi:10.1002/rmv.418 · Cited by 69 · see citing works
Formation of Virus Assembly Intermediate Complexes in the Cytoplasm by Wild-Type and Assembly-Defective Mutant Human Immunodeficiency Virus Type 1 and Their Association with Membranes
Lee, Y. M., Liu, B., & Yu, X.-F. (1999) · Journal of Virology · doi:10.1128/jvi.73.7.5654-5662.1999 · Cited by 67 · see citing works
A viral protease-mediated cleavage of the transmembrane glycoprotein of Mason-Pfizer monkey virus can be suppressed by mutations within the matrix protein
Brody, B. A., Rhee, S. S., Sommerfelt, M. A., & Hunter, E. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.8.3443 · Cited by 66 · see citing works
Self-citation
Intracellular Transport of Retroviral Capsid Components
Kräusslich, H., & Welker, R. (1996) · Current topics in microbiology and immunology · doi:10.1007/978-3-642-80145-7_2 · Cited by 65 · see citing works
Type D Retrovirus Gag Polyprotein Interacts with the Cytosolic Chaperonin TRiC
Hong, S., Choi, G., Park, S., Chung, A., Hunter, E., & Rhee, S. (2001) · Journal of Virology · doi:10.1128/jvi.75.6.2526-2534.2001 · Cited by 64 · see citing works
Self-citation
Identification of a Conserved Residue of Foamy Virus Gag Required for Intracellular Capsid Assembly
Eastman, S. W., & Linial, M. L. (2001) · Journal of Virology · doi:10.1128/jvi.75.15.6857-6864.2001 · Cited by 63 · see citing works
HIV-1 and M-PMV RNA Nuclear Export Elements Program Viral Genomes for Distinct Cytoplasmic Trafficking Behaviors
Pocock, G. M., Becker, J. T., Swanson, C. M., Ahlquist, P., & Sherer, N. M. (2016) · PLoS Pathogens · doi:10.1371/journal.ppat.1005565 · Cited by 58 · see citing works
Retroviral Matrix Proteins: A Structural Perspective
Conte, M. R., & Matthews, S. (1998) · Virology · doi:10.1006/viro.1998.9206 · Cited by 61 · see citing works
Identification of a cytoplasmic targeting/retention signal in a retroviral Gag polyprotein
Choi, G., Park, S., Choi, B., Hong, S., Lee, J., Hunter, E., & Rhee, S. S. (1999) · Journal of Virology · doi:10.1128/jvi.73.7.5431-5437.1999 · Cited by 61 · see citing works
Self-citation
Three-dimensional structure of the HTLV-II matrix protein and comparative analysis of matrix proteins from the different classes of pathogenic human retroviruses
Christensen, A. M., Massiah, M. A., Turner, B. G., Sundquist, W. I., & Summers, M. F. (1996) · Journal of Molecular Biology · doi:10.1006/jmbi.1996.0700 · Cited by 59 · see citing works
Foamy Virus Capsid Assembly Occurs at a Pericentriolar Region Through a Cytoplasmic Targeting/Retention Signal in Gag
Yu, S. F., Eastman, S. W., & Linial, M. L. (2006) · Traffic · doi:10.1111/j.1600-0854.2006.00448.x · Cited by 59 · see citing works
Basic residues in the Mason-Pfizer monkey virus gag matrix domain regulate intracellular trafficking and capsid-membrane interactions
Stansell, E., Apkarian, R., Haubova, S., Diehl, W. E., Tytler, E. M., & Hunter, E. (2007) · Journal of Virology · doi:10.1128/jvi.00657-07 · Cited by 59 · see citing works
Self-citation
Assembly-defective point mutants of the human immunodeficiency virus type 1 Gag precursor phenotypically expressed in recombinant baculovirus-infected cells
Hong, S. S., & Boulanger, P. A. (1993) · Journal of Virology · doi:10.1128/jvi.67.5.2787-2798.1993 · Cited by 59 · see citing works
The three‐dimensional solution structure of the matrix protein from the type D retrovirus, the Mason–Pfizer monkey virus, and implications for the morphology of retroviral assembly
Conte, M. R., Rumlová, M., Hunter, E., Ruml, T., & Matthews, S. (1997) · The EMBO Journal · doi:10.1093/emboj/16.19.5819 · Cited by 59 · see citing works
Self-citation
Preformed cytoplasmic nucleocapsids are not necessary for alphavirus budding.
Forsell, K., Griffiths, G., & Garoff, H. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb01040.x · Cited by 55 · see citing works
Characterization of Prototype Foamy Virus Gag Late Assembly Domain Motifs and Their Role in Particle Egress and Infectivity
Stange, A., Mannigel, I., Peters, K., Heinkelein, M., Stanke, N., Cartellieri, M., Göttlinger, H. G., Rethwilm, A., Zentgraf, H., & Lindemann, D. (2005) · Journal of Virology · doi:10.1128/jvi.79.9.5466-5476.2005 · Cited by 51 · see citing works
Molecular Biology of Jaagsiekte Sheep Retrovirus
Palmarini, M., & Fan, H. (2003) · Current topics in microbiology and immunology · doi:10.1007/978-3-642-55638-8_4 · Cited by 51 · see citing works
Human immunodeficiency virus type 1 capsid formation in reticulocyte lysates
Spearman, P. W., & Ratner, L. (1996) · Journal of Virology · doi:10.1128/jvi.70.11.8187-8194.1996 · Cited by 51 · see citing works
Human immunodeficiency virus type 1 MA deletion mutants expressed in baculovirus-infected cells: cis and trans effects on the Gag precursor assembly pathway
Chazal, N., Gay, B., Carrière, C., Tournier, J., & Boulanger, P. A. (1995) · Journal of Virology · doi:10.1128/jvi.69.1.365-375.1995 · Cited by 51 · see citing works
Mutations in the Ty3 major homology region affect multiple steps in Ty3 retrotransposition
Orlinsky, K. J., Gu, J., Hoyt, M., Sandmeyer, S. B., & Menees, T. M. (1996) · Journal of Virology · doi:10.1128/jvi.70.6.3440-3448.1996 · Cited by 50 · see citing works
Origin and General Nature of Retroviruses
Temin, H. M. (1992) · Springer eBooks · doi:10.1007/978-1-4615-3372-6_1 · Cited by 50 · see citing works
Analyses of the requirements for the synthesis of virus-like particles by feline immunodeficiency virus gag using baculovirus vectors.
Morikawa, S., Booth, T., & Bishop, D. H. L. (1991) · Virology · doi:10.1016/0042-6822(91)90141-w · Cited by 55 · see citing works
Centrosome and retroviruses: The dangerous liaisons
Afonso, P. V., Zamborlini, A., Saı̈b, A., & Mahieux, R. (2007) · Retrovirology · doi:10.1186/1742-4690-4-27 · Cited by 49 · see citing works
HEED, the Product of the Human Homolog of the Murineeed Gene, Binds to the Matrix Protein of HIV-1
Peytavi, R., Hong, S. S., Gay, B., d’Angeac, A. D., Selig, L., Bénichou, S., Bénarous, R., & Boulanger, P. A. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.3.1635 · Cited by 49 · see citing works
The Simian Retroviruses SIV and SRV
Gardner, M. B., Endres, M. J., & Barry, P. A. (1994) · Springer eBooks · doi:10.1007/978-1-4899-1730-0_5 · Cited by 46 · see citing works
Advances in HIV-1 Assembly
Lerner, G., Weaver, N. C., Anokhin, B., & Spearman, P. W. (2022) · Viruses · doi:10.3390/v14030478 · Cited by 43 · see citing works
Structure of Equine Infectious Anemia Virus Matrix Protein
Hatanaka, H., Iourin, O., Rao, Z., Fry, E. E., Kingsman, A. J., & Stuart, D. I. (2002) · Journal of Virology · doi:10.1128/jvi.76.4.1876-1883.2002 · Cited by 41 · see citing works
Understanding retroviral life cycle and its genomic RNA packaging
Chameettachal, A., Mustafa, F., & Rizvi, T. A. (2023) · Journal of Molecular Biology · doi:10.1016/j.jmb.2022.167924 · Cited by 41 · see citing works
D-retrovirus morphogenetic switch driven by the targeting signal accessibility to Tctex-1 of dynein
Vlach, J., Lipov, J., Rumlová, M., Veverka, V., Lang, J., Srb, P., Knejzlík, Z., Pichová, I., Hunter, E., Hrabal, R., et al. (2008) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.0801765105 · Cited by 40 · see citing works
Self-citation
Separate Assembly and Transport Domains within the Gag Precursor of Mason-Pfizer Monkey Virus
Sakalian, M., & Hunter, E. (1999) · Journal of Virology · doi:10.1128/jvi.73.10.8073-8082.1999 · Cited by 39 · see citing works
Self-citation
Human Foamy Virus Capsid Formation Requires an Interaction Domain in the N Terminus of Gag
Tobaly-Tapiero, J., Bittoun, P., Giron, M.-L., Neves, M., Koken, M. H. M., Saı̈b, A., & de Thé, H. (2001) · Journal of Virology · doi:10.1128/jvi.75.9.4367-4375.2001 · Cited by 39 · see citing works
The solution structure of the bovine leukaemia virus matrix protein and similarity with lentiviral matrix proteins.
Matthews, S., Mikhailov, M., Burny, A., & Roy, P. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00691.x · Cited by 39 · see citing works
REVIEW ARTICLE: An updated review of simianbetaretrovirus(SRV) in macaque hosts
Montiel, N. A. (2010) · Journal of Medical Primatology · doi:10.1111/j.1600-0684.2010.00412.x · Cited by 38 · see citing works
Particle Assembly and Genome Packaging
Linial, M. L., & Eastman, S. W. (2003) · Current topics in microbiology and immunology · doi:10.1007/978-3-642-55701-9_4 · Cited by 38 · see citing works
Towards the structure of the human immunodeficiency virus: divide and conquer?
Wilk, T., & Fuller, S. D. (1999) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(99)80033-5 · Cited by 38 · see citing works
In Vitro Cell-Free Conversion of Noninfectious Moloney Retrovirus Particles to an Infectious Form by the Addition of the Vesicular Stomatitis Virus Surrogate Envelope G Protein
Abe, A., Chen, S., Miyanohara, A., & Friedmann, T. (1998) · Journal of Virology · doi:10.1128/jvi.72.8.6356-6361.1998 · Cited by 35 · see citing works
Mutations in the Amino Terminus of Foamy Virus Gag Disrupt Morphology and Infectivity but Do Not Target Assembly
Life, R. B., Lee, E.-G., Eastman, S. W., & Linial, M. L. (2008) · Journal of Virology · doi:10.1128/jvi.00503-08 · Cited by 34 · see citing works
Human Immunodeficiency Virus Type-1 Gag and Host Vesicular Trafficking Pathways
Chu, H., Wang, J.-J., & Spearman, P. W. (2009) · Current topics in microbiology and immunology · doi:10.1007/978-3-642-02175-6_4 · Cited by 34 · see citing works
Tracing the Origin of Retroviruses
Doolittle, R. F., & Feng, D.-F. (1992) · Current topics in microbiology and immunology · doi:10.1007/978-3-642-77011-1_13 · Cited by 32 · see citing works
Assembly and composition of intracellular particles formed by Moloney murine leukemia virus
Hansen, M., Jelinek, L., Jones, R. S., Stegeman-Olsen, J., & Barklis, E. (1993) · Journal of Virology · doi:10.1128/jvi.67.9.5163-5174.1993 · Cited by 34 · see citing works
The cytoplasmic domain of the human T-cell leukemia virus type I envelope can modulate envelope functions in a cell type-dependent manner
Pique, C., Pham, D., Tursz, T., & Dokhélar, M. (1993) · Journal of Virology · doi:10.1128/jvi.67.1.557-561.1993 · Cited by 34 · see citing works
A Unique Spumavirus Gag N-terminal Domain with Functional Properties of Orthoretroviral Matrix and Capsid
Goldstone, D. C., Flower, T. G., Ball, N. J., Sanz-Ramos, M., Yap, M. W., Ogrodowicz, R. W., Stanke, N., Reh, J., Lindemann, D., Stoye, J. P., et al. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003376 · Cited by 32 · see citing works
Budding of enveloped viruses from the plasma membrane
Cadd, T. L., Skoging, U., & Liljeström, P. (1997) · Bioessays · doi:10.1002/bies.950191109 · Cited by 30 · see citing works
Type D Retrovirus Capsid Assembly and Release Are Active Events Requiring ATP
Weldon, R. A., Parker, W. B., Sakalian, M., & Hunter, E. (1998) · Journal of Virology · doi:10.1128/jvi.72.4.3098-3106.1998 · Cited by 32 · see citing works
Self-citation
Link between Genome Packaging and Rate of Budding for Rous Sarcoma Virus
Callahan, E. M., & Wills, J. W. (2003) · Journal of Virology · doi:10.1128/jvi.77.17.9388-9398.2003 · Cited by 31 · see citing works
Pleiotropic Mutations in the HIV-1 Matrix Protein That Affect Diverse Steps in Replication
Casella, C. R., Raffini, L. J., & Panganiban, A. T. (1997) · Virology · doi:10.1006/viro.1996.8355 · Cited by 29 · see citing works
Regulation of HIV-1 gag Protein Subcellular Targeting by Protein Kinase C
Yu, G., Shen, F. S., Sturch, S., Aquino, A., Glazer, R. I., & Felsted, R. L. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.9.4792 · Cited by 29 · see citing works
HIV-1 Replication and Potential Targets for Intervention
Stevenson, M., Bukrinsky, M., & Haggerty, S. (1992) · AIDS Research and Human Retroviruses · doi:10.1089/aid.1992.8.107 · Cited by 29 · see citing works
Plasma membrane targeting of chimeric intracisternal A-type particle polyproteins leads to particle release and specific activation of the viral proteinase
Welker, R., Janetzko, A., & Kräusslich, H. (1997) · Journal of Virology · doi:10.1128/jvi.71.7.5209-5217.1997 · Cited by 29 · see citing works

Identification of a cytoplasmic targeting/retention signal in a retroviral Gag polyprotein
Choi, G., Park, S., Choi, B., Hong, S., Lee, J., Hunter, E., & Rhee, S. S. (1999) · Journal of Virology · doi:10.1128/jvi.73.7.5431-5437.1999 · Cited by 61 · see citing works
Self-citation
Amino acid substitutions within the matrix protein of type D retroviruses affect assembly, transport and membrane association of a capsid
Rhee, S. S., & Hunter, E. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07980.x · Cited by 92 · see citing works
Self-citation
The three‐dimensional solution structure of the matrix protein from the type D retrovirus, the Mason–Pfizer monkey virus, and implications for the morphology of retroviral assembly
Conte, M. R., Rumlová, M., Hunter, E., Ruml, T., & Matthews, S. (1997) · The EMBO Journal · doi:10.1093/emboj/16.19.5819 · Cited by 59 · see citing works
Self-citation
Separate Assembly and Transport Domains within the Gag Precursor of Mason-Pfizer Monkey Virus
Sakalian, M., & Hunter, E. (1999) · Journal of Virology · doi:10.1128/jvi.73.10.8073-8082.1999 · Cited by 39 · see citing works
Self-citation
Preassembled capsids of type D retroviruses contain a signal sufficient for targeting specifically to the plasma membrane
Rhee, S. S., Hui, H., & Hunter, E. (1990) · Journal of Virology · doi:10.1128/jvi.64.8.3844-3852.1990 · Cited by 75 · see citing works
Self-citation

Authors: Rhee, S. S., & Hunter, E.
Affiliations: University of Alabama at Birmingham (US)
ORCID: Hunter, Eric
Venue: Cell
Publisher: Elsevier BV
Published: 1990-10
Volume: 63
Issue: 1
Pages: 77-86
ISSN: 0092-8674 (ISSN-L)
DOI: 10.1016/0092-8674(90)90289-q
OpenAlex: W2130138608
Cited by: 160
References: 67
Citations by year: 2026: 1 · 2025: 2 · 2024: 2 · 2022: 2 · 2021: 1 · 2020: 2 · 2019: 1 · 2018: 3 · 2017: 1 · 2016: 2 · 2015: 2 · 2013: 4
FWCI: 4.30
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Cell (publishedVersion)
PubMed (publishedVersion)
Funders: National Cancer Institute (CA27834)
Topics: Life Sciences › Immunology and Microbiology › Immunology › T-cell and Retrovirus Studies
Life Sciences › Immunology and Microbiology › Virology › HIV Research and Treatment
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
Keywords: capsid assembly, matrix protein, type D retroviruses, type C retroviruses, Mason-Pfizer monkey virus, Gag protein, amino acid substitutions, tryptophan substitution, intracellular trafficking
MeSH terms: Amino Acid Sequence, Animals, Capsid, Cell Line, Clone Cells, HeLa Cells, Molecular Sequence Data, Morphogenesis, Mutation, Retroviridae, Sequence Homology, Nucleic Acid, Transfection, Viral Matrix Proteins, Virion, Gene Products, gag, Betaretrovirus

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

A single amino acid substitution within the matrix protein of a type D retrovirus converts its morphogenesis to that of a type C retrovirus

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks