Cited by 218Clinical Nutrition and GastroenterologyGastrointestinal motility and disordersEnhanced Recovery After Surgery

Jejunal efflux in short bowel syndrome

Nightingale, J.M.D., Lennard-Jones, J.E., Walker, E.R., Farthing, MJG·1990·The Lancet

Abstract

24 h oral intake and intestinal output were studied in 15 patients with a short residual length of jejunum and no colon. 8 patients showed a net secretory, and 7 a net absorptive response to food. In secretors, daily intestinal output exceeded oral intake (mean 2.3 kg wet weight, and 233 mmol sodium). Long-term parenteral fluid and electrolyte replacements were needed only in those with a secretory response. Jejunal length inversely correlated with net intestinal output of fluid, sodium, potassium, and with percentage energy absorption. A secretory response was observed if jejunal length was less than 100 cm and was reduced by gastric antisecretory drugs and octreotide.

Integrity signals

Registry

Crossref · 10.1016/0140-6736(90)93238-k

Cites

12 of 12 references verified0 citation errors · 0 not checkable

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  • Management of patients with SBS can be challenging, especially in case of ostomies with associated large fluid losses and electrolyte imbalances.

    “Management of patients with SBS can be challenging, especially in case of ostomies with associated large fluid losses and electrolyte imbalances [148].”

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Authors
Nightingale, J. M. D., Lennard-Jones, J. E., Walker, E. R., & Farthing, M.
Affiliations
St Mark's Hospital (GB)
Venue
The Lancet
Publisher
Elsevier BV
Published
1990-09
Volume
336
Issue
8718
Pages
765-768
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
OpenAlex
W1980944037
Cited by
218
References
12
Citations by year
2026: 3 · 2025: 3 · 2024: 6 · 2023: 13 · 2022: 4 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 5 · 2017: 8 · 2016: 9 · 2015: 2 · 2014: 11 · 2013: 2 · 2012: 4
FWCI
5.16
Type
journal article
Language
en
Open access
closed
Locations
  • The Lancet (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Health Sciences › Medicine › Surgery › Enhanced Recovery After Surgery
Keywords
short bowel syndrome, intestinal secretion, intestinal absorption, sodium loss, potassium excretion, energy absorption, octreotide
MeSH terms
Administration, Oral, Adult, Female, Food, Humans, Injections, Intravenous, Intestinal Absorption, Jejunostomy, Jejunum, Malabsorption Syndromes, Male, Middle Aged, Omeprazole, Parenteral Nutrition, Potassium, Ranitidine, Short Bowel Syndrome, Sodium, Octreotide

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