Jejunal efflux in short bowel syndrome
Abstract
24 h oral intake and intestinal output were studied in 15 patients with a short residual length of jejunum and no colon. 8 patients showed a net secretory, and 7 a net absorptive response to food. In secretors, daily intestinal output exceeded oral intake (mean 2.3 kg wet weight, and 233 mmol sodium). Long-term parenteral fluid and electrolyte replacements were needed only in those with a secretory response. Jejunal length inversely correlated with net intestinal output of fluid, sodium, potassium, and with percentage energy absorption. A secretory response was observed if jejunal length was less than 100 cm and was reduced by gastric antisecretory drugs and octreotide.
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Management of patients with SBS can be challenging, especially in case of ostomies with associated large fluid losses and electrolyte imbalances.
“Management of patients with SBS can be challenging, especially in case of ostomies with associated large fluid losses and electrolyte imbalances [148].”
From Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery. (2022) · cites this paper as [148]
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- Authors
- Nightingale, J. M. D., Lennard-Jones, J. E., Walker, E. R., & Farthing, M.
- Affiliations
- St Mark's Hospital (GB)
- ORCID
- Nightingale, J.M.D.
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 1990-09
- Volume
- 336
- Issue
- 8718
- Pages
- 765-768
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W1980944037
- Cited by
- 218
- References
- 12
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 6 · 2023: 13 · 2022: 4 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 5 · 2017: 8 · 2016: 9 · 2015: 2 · 2014: 11 · 2013: 2 · 2012: 4
- FWCI
- 5.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Surgery › Enhanced Recovery After Surgery
- Keywords
- short bowel syndrome, intestinal secretion, intestinal absorption, sodium loss, potassium excretion, energy absorption, octreotide
- MeSH terms
- Administration, Oral, Adult, Female, Food, Humans, Injections, Intravenous, Intestinal Absorption, Jejunostomy, Jejunum, Malabsorption Syndromes, Male, Middle Aged, Omeprazole, Parenteral Nutrition, Potassium, Ranitidine, Short Bowel Syndrome, Sodium, Octreotide
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