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LECT2 functions as a hepatokine that links obesity to skeletal muscle insulin resistance

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LECT2 protects mice against bacterial sepsis by activating macrophages via the CD209a receptor

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Identification of the leukocyte cell-derived chemotaxin 2 as a direct target gene of β-catenin in the liver

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Characterization and outcomes of renal leukocyte chemotactic factor 2-associated amyloidosis

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A strategy of vascular‐targeted therapy for liver fibrosis

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Leukocyte Chemotactic Factor 2 (LECT2)-Associated Renal Amyloidosis: A Case Series

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New insights into molecular pathways associated with flatfish ovarian development and atresia revealed by transcriptional analysis

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Suppressive role of leukocyte cell–derived chemotaxin 2 in mouse anti–type II collagen antibody–induced arthritis

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LECT2 as a hepatokine links liver steatosis to inflammation via activating tissue macrophages in NASH

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Leukocyte cell-derived chemotaxin 2 antagonizes MET receptor activation to suppress hepatocellular carcinoma vascular invasion by protein tyrosine phosphatase 1B recruitment

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LECT2 induces atherosclerotic inflammatory reaction via CD209 receptor-mediated JNK phosphorylation in human endothelial cells

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MAPK Signaling Pathways in Hepatic Ischemia/Reperfusion Injury

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Expression of a Neutrophil Chemotactic Protein LECT2 in Human Hepatocytes Revealed by Immunochemical Studies Using Polyclonal and Monoclonal Antibodies to a Recombinant LECT2

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Increased serum leukocyte cell-derived chemotaxin 2 (LECT2) levels in obesity and fatty liver

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Therapeutic Approaches to Nonalcoholic Fatty Liver Disease: Exercise Intervention and Related Mechanisms

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LECT2 promotes inflammation and insulin resistance in adipocytes via P38 pathways

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Immune modulatory properties of 6-gingerol and resveratrol in Atlantic salmon macrophages

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Kupffer cell programming by maternal obesity triggers fatty liver disease

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LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells

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Deficiency of Mbd2 Attenuates Wnt Signaling

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Globular Hepatic Amyloid Is Highly Sensitive and Specific for LECT2 Amyloidosis

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Gene expression patterns associated with chicken jejunal development

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Serum LECT2 level as a prognostic indicator in acute liver failure

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LECT2 improves the outcomes in ayu with Vibrio anguillarum infection via monocytes/macrophages

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Rapid response of the steatosis-sensing hepatokine LECT2 during diet-induced weight cycling in mice

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Changes in hepatic gene expression related to innate immunity, growth and iron metabolism in GH-transgenic amago salmon (Oncorhynchus masou) by cDNA subtraction and microarray analysis, and serum lysozyme activity

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iTRAQ-based proteomics reveals novel biomarkers of osteoarthritis

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Diagnostic amyloid proteomics: experience of the UK National Amyloidosis Centre

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Osteoclasts Secrete the Chemotactic Cytokine Mim-1

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Hepatokines: unveiling the molecular and cellular mechanisms connecting hepatic tissue to insulin resistance and inflammation

Miao, X., Alidadipour, A., Saed, V., Sayyadi, F., Jadidi, Y., Davoudi, M., Amraee, F., Jadidi, N., & Afrisham, R. (2024) · Acta Diabetologica · doi:10.1007/s00592-024-02335-9 · Cited by 37

Characterization of the LECT2 gene and its associations with resistance to the big belly disease in Asian seabass

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Sequencing of the first ayu (Plecoglossus altivelis) macrophage transcriptome and microarray development for investigation the effect of LECT2 on macrophages

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Genomic resources for flatfish research and their applications

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LECT2 Protects Nile Tilapia (Oreochromis niloticus) Against Streptococcus agalatiae Infection

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The inhibitory effect of environmental ammonia on Danio rerio LPS induced acute phase response

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Role of Leukocyte Cell-Derived Chemotaxin 2 as a Biomarker in Hepatocellular Carcinoma

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Identification of hepatokines involved in pathology of type 2 diabetes and obesity

Misu, H. (2019) · Endocrine Journal · doi:10.1507/endocrj.ej19-0255 · Cited by 32

Changes in serum LECT 2 levels during the early period of liver regeneration after adult living related donor liver transplantation

Sato, Y., Watanabe, H., Kameyama, H., Kobayashi, T., Yamamoto, S., Takeishi, T., Hirano, K., Oya, H., Nakatsuka, H., Watanabe, T., et al. (2004) · Transplantation Proceedings · doi:10.1016/j.transproceed.2004.07.006 · Cited by 32

An interaction between a C-type lectin receptor and leukocyte cell-derived chemotaxin 2 of ayu, Plecoglossus altivelis

Chen, J., Lü, X., Yang, H., & Shi, Y. H. (2009) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2009.10.011 · Cited by 32

LECT2 amyloidosis

Benson, M. D. (2010) · Kidney International · doi:10.1038/ki.2010.18 · Cited by 32

Molecular cloning of leukocyte cell-derived chemotaxin 2 in rainbow trout

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Molecular cloning of leucocyte cell-derived chemotaxin-2 gene in croceine croaker (Pseudosciaena crocea)

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Beyond being innervated: the epidermis actively shapes sensory dendritic patterning

Yang, W.-K., & Chien, C. (2019) · Open Biology · doi:10.1098/rsob.180257 · Cited by 28

Expression pattern of a newly recognized protein, LECT2, in hepatocellular carcinoma and its premalignant lesion

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Interorgan communication with the liver: novel mechanisms and therapeutic targets

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LECT2 Is a Novel Antibacterial Protein in Vertebrates

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Plasma leukocyte cell‐derived chemotaxin 2 is associated with the severity of systemic inflammation in patients with sepsis

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The mouse Lect2 gene: cloning of cDNA and genomic DNA, structural characterization and chromosomal localization

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Crystal Structure of Human Leukocyte Cell-derived Chemotaxin 2 (LECT2) Reveals a Mechanistic Basis of Functional Evolution in a Mammalian Protein with an M23 Metalloendopeptidase Fold

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Identification and expression profile of multiple genes in the anterior kidney of channel catfish induced by modified live Edwardsiella ictaluri vaccination

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