The DOI matches its Crossref record; 321 of the 325 references it cites were found in a registry or an index.
Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseases
Abstract
This review summarizes the current knowledge of characterized neurotrophic factors, including nerve growth factor (NGF) which serves as paradigmatic example when studying novel molecules. Special consideration is given to the function of neurotrophic factors in the adult and aging brain. Strategies are discussed for the eventual development of pharmacological applications of these molecules in the treatment of neurodegenerative diseases.
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“It is known that BDNF exerts positive effects such as anti-apoptosis, anti-inflammation, anti-neurotoxicity and neural regeneration.”
From Beneficial Effects of Spirulina Consumption on Brain Health (2022) · cites this paper as [99]
Citations
Cites
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Cited by
Sorted by citations
Neurotrophins: Roles in Neuronal Development and Function
Huang, E. J., & Reichardt, L. F. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.677 · Cited by 4,394
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BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease
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Metadata
- Authors
- Hefti, F., Hartikka, J., & Knusel, B.
- Affiliations
- University of Southern California (US)
- Venue
- Neurobiology of Aging
- Publisher
- Elsevier BV
- Published
- 1989-09
- Volume
- 10
- Issue
- 5
- Pages
- 515-533
- ISSN
- 0197-4580 (ISSN-L)
- OpenAlex
- W2020771907
- Cited by
- 466
- References
- 325
- Citations by year
- 2024: 4 · 2023: 2 · 2022: 1 · 2021: 3 · 2020: 3 · 2019: 5 · 2018: 1 · 2017: 2 · 2016: 2 · 2015: 3 · 2014: 3 · 2012: 2
- FWCI
- 5.09
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neurobiology of Aging (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Neurological Disorders and Stroke (NS-22933)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nerve injury and regeneration
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nuclear Receptors and Signaling
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- neurotrophic factors, nerve growth factor, brain aging, adult brain, neurodegenerative diseases, neurotrophic therapy, neuroprotection
- MeSH terms
- Aging, Alzheimer Disease, Animals, Humans, Nerve Growth Factors, Nervous System, Nervous System Physiological Phenomena, Parkinson Disease
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