The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Age-related decline in MRI volumes of temporal lobe gray matter but not hippocampus
Open accessAbstract
The effect of normal aging on the volume of the hippocampus and temporal cortex was assessed cross-sectionally with quantitative Magnetic Resonance Imaging (MRI) in 72 healthy men, spanning 5 decades of the adult age range (21 to 70 years). Neither the hippocampal nor cortical white matter volumes were significantly correlated with age. By contrast, left and right temporal lobe gray matter volumes, exclusive of the hippocampal measures, each decreased with age (p < 0.01). Volumes of temporal lobe sulcal CSF and the ventricular system (temporal horns and lateral and third ventricles) significantly increased with age. Measures of verbal and nonverbal working memory showed age-related declines and were related to enlargement of the three ventricular regions, which may be indicative of age-related atrophy of the adjacent cortex but not the hippocampus, at least up to age 70 years.
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Cites
The Medial Temporal Lobe Memory System
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Cited by
Lupien, S. J., Maheu, F., Tu, M., Fiocco, A., & Schramek, T. E. (2007) · Brain and Cognition · doi:10.1016/j.bandc.2007.02.007 · Cited by 1,474
Medial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease
Jack, C. R., Petersen, R. C., Xu, Y. C., Waring, S. C., O'Brien, P. C., Tangalos, E. G., Smith, G. E., Ivnik, R. J., & Kokmen, E. (1997) · Neurology · doi:10.1212/wnl.49.3.786 · Cited by 1,128
Traumatic stress: effects on the brain
Bremner, J. D. (2006) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2006.8.4/jbremner · Cited by 738
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Metadata
- Authors
- Sullivan, E. V., Marsh, L., Mathalon, D. H., Lim, K. O., & Pfefferbaum, A.
- Venue
- Neurobiology of Aging
- Publisher
- Elsevier BV
- Published
- 1995-07
- Volume
- 16
- Issue
- 4
- Pages
- 591-606
- ISSN
- 0197-4580 (ISSN-L)
- OpenAlex
- W2006716233
- Cited by
- 259
- References
- 3
- FWCI
- 9.03
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Sullivan, E. V., Marsh, L., Mathalon, D. H., Lim, K. O., & Pfefferbaum, A. (1995). Age-related decline in MRI volumes of temporal lobe gray matter but not hippocampus. Neurobiology of Aging. https://doi.org/10.1016/0197-4580(95)00074-o
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