Anterior temporal lobes and hippocampal formations: normative volumetric measurements from MR images in young adults.
Abstract
Volumes of the right and left anterior temporal lobes and hippocampal formations were measured from magnetic resonance images in 52 healthy volunteers, aged 20-40 years. Subjects were selected by age, sex, and handedness to evaluate possible effect of these variables. Data were normalized for variation in total intracranial volume between individuals. Right-left asymmetry in the volumes of the anterior temporal lobes and hippocampal formations was a normal finding. The anterior temporal lobe of the non-dominant (right) hemisphere was larger than the left by a small (mean right-left difference, 2.3 cm3) but statistically significant amount (P less than .005) in right-handed subjects. No significant effect of age or sex was seen in normalized right or left anterior temporal lobe volume. The right hippocampal formation was larger than the left for all subjects by a small (mean right-left difference, 0.3 cm3) but statistically significant amount (P less than .001). No effect of age, sex, or handedness was seen in normalized hippocampal formation volumes.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Baseline hippocampal volume measurements were normalized for interindividual variation in head size, age, and gender.
“In order to compare the baseline hippocampal volume (i.e., hippocampal volume at the time of the initial MR scan) among groups, the hippocampal volume measurements were normalized for interindividual variation in head size, age, and gender (16).”
From Rates of hippocampal atrophy correlate with change in clinical status in aging and AD (2000) · cites this paper as [16]
Cited by
Sorted by citations
Scheltens, P., Leys, D., Barkhof, F., Huglo, D. G., Weinstein, H. C., Vermersch, P., Kuiper, M. A., Steinling, M., Wolters, E. C., & Valk, J. (1992) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.55.10.967 · Cited by 1,781 · see citing works
Buckner, R. L., Head, D. M., Parker, J. B., Fotenos, A. F., Marcus, D. S., Morris, J. C., & Snyder, A. Z. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.06.018 · Cited by 1,290 · see citing works
“(1); Free et al., 1995; Jack et al., 1989; Mathalon et al., 1993}.”
MethodMedial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease
Jack, C. R., Petersen, R. C., Xu, Y. C., Waring, S. C., O'Brien, P. C., Tangalos, E. G., Smith, G. E., Ivnik, R. J., & Kokmen, E. (1997) · Neurology · doi:10.1212/wnl.49.3.786 · Cited by 1,128 · see citing works
Self-citationJack, C. R., Lowe, V. J., Weigand, S. D., Wiste, H. J., Senjem, M. L., Knopman, D. S., Shiung, M. M., Gunter, J. L., Boeve, B. F., Kemp, B. J., et al. (2009) · Brain · doi:10.1093/brain/awp062 · Cited by 1,099 · see citing works
“Baseline ventricular volume was measured from the ventricular mask, and was normalized for inter-subject variation in head size by dividing ventricular volume by that subject’s total intra-cranial volume (TIV) as described in Jack et al .”
Self-citationJack, C. R., Lowe, V. J., Senjem, M. L., Weigand, S. D., Kemp, B. J., Shiung, M. M., Knopman, D. S., Boeve, B. F., Klunk, W. E., Mathis, C. A., et al. (2008) · Brain · doi:10.1093/brain/awm336 · Cited by 958 · see citing works
Self-citationRates of hippocampal atrophy correlate with change in clinical status in aging and AD
Jack, C. R., Petersen, R. C., Xu, Y., O’Brien, P. C., Smith, G. E., Ivnik, R. J., Boeve, B. F., Tangalos, E. G., & Kokmen, E. (2000) · Neurology · doi:10.1212/wnl.55.4.484 · Cited by 937 · see citing works
Self-citationScahill, R. I., Frost, C. D., Jenkins, R., Whitwell, J. L., Rossor, M. N., & Fox, N. C. (2003) · Archives of Neurology · doi:10.1001/archneur.60.7.989 · Cited by 924 · see citing works
Starkman, M. N., Gebarski, S. S., Berent, S., & Schteingart, D. E. (1992) · Biological Psychiatry · doi:10.1016/0006-3223(92)90079-f · Cited by 840 · see citing works
“Using the Jack et al technique, the right HF volume was 3.68 cm 3, the left 3.42, and the total intracranial volume 1954 cm 3, with an index of 0.0036.”
BackgroundMethodResultInfluentialMR volumetric analysis of the human entorhinal, perirhinal, and temporopolar cortices.
Insausti, R., Juottonen, K., Soininen, H. S., Insausti, A. M., Partanen, K. P. L., Vainio, P. A., Laakso, M. P., & Pitkänen, A. (1998) · PubMed Central · Cited by 774 · see citing works
Pruessner, J. C. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.4.433 · Cited by 706 · see citing works
Presymptomatic hippocampal atrophy in Alzheimer's disease: A longitudinal MRI study
Fox, N. C., Warrington, E. K., Freeborough, P. A., Hartikainen, P., Kennedy, A. M., Stevens, J. M., & Rossor, M. N. (1996) · Brain · doi:10.1093/brain/119.6.2001 · Cited by 656 · see citing works
Trajectories of brain aging in middle-aged and older adults: Regional and individual differences
Raz, N., Ghisletta, P., Rodrigue, K. M., Kennedy, K. M., & Lindenberger, U. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.03.020 · Cited by 626 · see citing works
“Before the analyses, all regional volumes were adjusted for the volume of the intracranial vault through a regression-ANCOVA approach described in previous publications (Jack et al., 1989; Raz et al., 2004).”
Jack, C. R., Knopman, D. S., Weigand, S. D., Wiste, H. J., Vemuri, P., Lowe, V., Kantarci, K., Gunter, J. L., Senjem, M. L., Ivnik, R. J., et al. (2012) · Annals of Neurology · doi:10.1002/ana.22628 · Cited by 602 · see citing works
“e4 carrier 38 [24] 25 [40] 20 [40] 7 [58] 12 [13] 1 [8]”
Self-citationJack, C. R., Wiste, H. J., Vemuri, P., Weigand, S. D., Senjem, M. L., Zeng, G., Bernstein, M. A., Gunter, J. L., Pankratz, V. S., Aisen, P. S., et al. (2010) · Brain · doi:10.1093/brain/awq277 · Cited by 531 · see citing works
“Hippocampal volumes were adjusted for total intracranial volumes by including total intracranial volumes as a covariate in the Cox models (Jack et al., 1989).”
Self-citationMagnetic resonance imaging–based volume studies in temporal lobe epilepsy: Pathological correlations
Cascino, G. D., Jack, C. R., Parisi, J. E., Sharbrough, F. W., Hirschorn, K. A., Meyer, F. B., Marsh, W. R., & O’Brien, P. C. (1991) · Annals of Neurology · doi:10.1002/ana.410300107 · Cited by 482 · see citing works
Self-citationHippocampal morphometry in schizophrenia by high dimensional brain mapping
Csernansky, J. G., Joshi, S. C., Wang, L., Haller, J. W., Gado, M. H., Miller, J. P., Grenander, U., & Miller, M. I. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.19.11406 · Cited by 469 · see citing works
Decrease in cortisol reverses human hippocampal atrophy following treatment of Cushing’s disease
Starkman, M. N., Giordani, B., Gebarski, S. S., Berent, S., Schork, M. A., & Schteingart, D. E. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00203-6 · Cited by 455 · see citing works
“The technique described by Jack et al (1989, 1990) was followed to delineate both the anterior and posterior portions of the hippocampus.”
MethodSchwarz, C. G., Gunter, J. L., Wiste, H. J., Przybelski, S. A., Weigand, S. D., Ward, C. P., Senjem, M. L., Vemuri, P., Murray, M. E., Dickson, D. W., et al. (2016) · NeuroImage Clinical · doi:10.1016/j.nicl.2016.05.017 · Cited by 422 · see citing works
“Since the introduction of hippocampal volumes, these and other volume measurements have been normalized by or corrected for intersubject variation in brain size or head size (Jack et al., 1992, 1989; Kesslak et al., 1991; Scheltens et al., 1992; Seab et al., 1988).”
BackgroundSelf-citationJack, C. R., Sharbrough, F. W., Cascino, G. D., Hirschorn, K. A., O’Brien, P. C., & Marsh, W. R. (1992) · Annals of Neurology · doi:10.1002/ana.410310204 · Cited by 433 · see citing works
Self-citationMR-based in vivo hippocampal volumetrics: 2. Findings in neuropsychiatric disorders
Geuze, E., Vermetten, E., & Bremner, J. D. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001579 · Cited by 412 · see citing works
Lencz, T., McCarthy, G., Bronen, R. A., Scott, T. M., Inserni, J. A., Sass, K. J., Novelly, R. A., Kim, J., & Spencer, D. D. (1992) · Annals of Neurology · doi:10.1002/ana.410310610 · Cited by 409 · see citing works
Swayze, V. W., Andreasen, N. C., Alliger, R. J., Yuh, W. T. C., & Ehrhardt, J. C. (1992) · Biological Psychiatry · doi:10.1016/0006-3223(92)90046-3 · Cited by 403 · see citing works
Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease
Benzinger, T. L. S., Blazey, T., Jack, C. R., Koeppe, R. A., Su, Y., Xiong, C., Raichle, M. E., Snyder, A. Z., Ances, B. M., Bateman, R. J., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1317918110 · Cited by 391 · see citing works
“Segmented volumes were corrected for intracranial volume using an analysis of covariance approach (80).”
MethodSelf-citationHippocampal sclerosis in temporal lobe epilepsy demonstrated by magnetic resonance imaging
Berkovic, S. F., Andermann, F., Olivier, A., Ethier, R., Melanson, D., ROBITAILLE, Y., Kuzniecky, R., Peters, T. M., & Feindel, W. (1991) · Annals of Neurology · doi:10.1002/ana.410290210 · Cited by 390 · see citing works
Brain Development Cooperative Group (2011) · Cerebral Cortex · doi:10.1093/cercor/bhr018 · Cited by 372 · see citing works
“findings in adults (Jack et al. 1989) and the tendency of the Sylvian fissure to course upward posteriorly at a steeper angle on the right than on the left, although this asymmetry may be”
BackgroundEliot, L., Ahmed, A., Khan, H., & Patel, J. Y. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.02.026 · Cited by 351 · see citing works
Modifiable factors that alter the size of the hippocampus with ageing
Fotuhi, M., Do, D., & Jack, C. R. (2012) · Nature Reviews Neurology · doi:10.1038/nrneurol.2012.27 · Cited by 358 · see citing works
Self-citationWhitwell, J. L., Crum, W. R., Watt, H., & Fox, N. C. (2001) · PubMed Central · Cited by 357 · see citing works
Anterior Hippocampal Volume Deficits in Nonamnesic, Aging Chronic Alcoholics
Sullivan, E. V., Marsh, L., Mathalon, D. H., Lim, K. O., & Pfefferbaum, A. (1995) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1995.tb01478.x · Cited by 343 · see citing works
Usefulness of MRI measures of entorhinal cortex versus hippocampus in AD
de Leon, M. J., Bobinski, M., Convit, A. J., Wolf, O. T., & Insausti, R. (2001) · Neurology · doi:10.1212/wnl.56.6.820 · Cited by 348 · see citing works
Lao, Z., Shen, D. G., Xue, Z., Karaçalı, B., Resnick, S. M., & Davatzikos, C. A. (2003) · NeuroImage · doi:10.1016/j.neuroimage.2003.09.027 · Cited by 343 · see citing works
“Several groups have also shown that temporal lobe measurements predict AD in patients with mild cognitive impairment (Jack et al., 1989; Killiany et al., 2000).”
Usefulness of MRI measures of entorhinal cortex versus hippocampus in AD
Xu, Y., Jack, C. R., O’Brien, P. C., Kokmen, E., Smith, G. E., Ivnik, R. J., Boeve, B. F., Tangalos, R. G., & Petersen, R. C. (2000) · Neurology · doi:10.1212/wnl.54.9.1760 · Cited by 336 · see citing works
Self-citationAge-related Volumetric Changes of Brain Gray and White Matter in Healthy Infants and Children
Matsuzawa, J. (2001) · Cerebral Cortex · doi:10.1093/cercor/11.4.335 · Cited by 315 · see citing works
Visser, P. J., Scheltens, P., Verhey, F. R. J., Schmand, B., Launer, L. J., Jolles, J., & Jonker, C. (1999) · Journal of Neurology · doi:10.1007/s004150050387 · Cited by 319 · see citing works
Geinisman, Y., deToledo‐Morrell, L., Morrell, F., & Heller, R. E. (1995) · Progress in Neurobiology · doi:10.1016/0301-0082(94)00047-l · Cited by 317 · see citing works
Chelune, G. J. (1995) · Archives of Clinical Neuropsychology · doi:10.1093/arclin/10.5.413 · Cited by 324 · see citing works
“Several investigators have developed volumetric methods of digitally reconstructing 3-D images of the hippocampal structures from tracings of coronal or angled TIweighted thin-slice MRI turboflash images (Ashtari, Barr, Schaul, & Bogerts, 1991; Cook, Fish, Shorvon, Straughan, & Stevens, 1992; Jack et al., 1989; Watson…”
MethodAutomatic Atlas-Based Volume Estimation of Human Brain Regions from MR Images
Andreasen, N. C., Rajarethinam, R., Cizadlo, T., Arndt, S. V., Swayze, V. W., Flashman, L. A., OʼLeary, D. S., Ehrhardt, J. C., & Yuh, W. T. C. (1996) · Journal of Computer Assisted Tomography · doi:10.1097/00004728-199601000-00018 · Cited by 312 · see citing works
Hippocampal volume in normal aging and traumatic brain injury.
Bigler, E. D., Blatter, D. D., Anderson, C. V., Johnson, S. C., Gale, S. D., Hopkins, R. O., & Burnett, B. (1997) · PubMed Central · Cited by 311 · see citing works
MRI as a biomarker of disease progression in a therapeutic trial of milameline for AD
Jack, C. R., Slomkowski, M., Gracon, S. I., Hoover, T. M., Felmlee, J. P., Stewart, K., Xu, Y., Shiung, M. S., O’Brien, P. C., Cha, R., et al. (2003) · Neurology · doi:10.1212/01.wnl.0000042480.86872.03 · Cited by 295 · see citing works
Self-citationAn Image-Processing System for Qualitative and Quantitative Volumetric Analysis of Brain Images
Goldszal, A. F., Davatzikos, C. A., Pham, D. L., Yan, M., Bryan, R. N., & Resnick, S. M. (1998) · Journal of Computer Assisted Tomography · doi:10.1097/00004728-199809000-00030 · Cited by 295 · see citing works
Age and gender predict volume decline in the anterior and posterior hippocampus in early adulthood
Pruessner, J. C., Collins, D. L., Pruessner, M., & Evans, A. C. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-01-00194.2001 · Cited by 292 · see citing works
In Vivo Quantitative Susceptibility Mapping (QSM) in Alzheimer's Disease
Acosta‐Cabronero, J., Williams, G. B., Cárdenas‐Blanco, A., Arnold, R. J., Lupson, V. C., & Nestor, P. J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0081093 · Cited by 290 · see citing works
“FIRST-segmented hippocampi, after satisfying a further visual inspection, were normalised by total intracranial volumes [85] determined using a previously validated method [86].”
MethodHippocampal abnormalities in amnesic patients revealed by high-resolution magnetic resonance imaging
Press, G. A., Amaral, D. G., & Squire, L. R. (1989) · Nature · doi:10.1038/341054a0 · Cited by 281 · see citing works
Interactive algorithms for the segmentation and quantitation of 3-D MRI brain scans
Freeborough, P. A., Fox, N. C., & Kitney, R. I. (1997) · Computer Methods and Programs in Biomedicine · doi:10.1016/s0169-2607(97)01803-8 · Cited by 276 · see citing works
Automatic Volumetry of the Cerebrospinal Fluid Space in Idiopathic Normal Pressure Hydrocephalus
Ishii, K., Soma, T., Shimada, K., Oda, H., Terashima, A., & Kawasaki, R. (2013) · Dementia and Geriatric Cognitive Disorders Extra · doi:10.1159/000357329 · Cited by 265 · see citing works
Laakso, M. P., Soininen, H. S., Partanen, K. P. L., Lehtovirta, M., Hallikainen, M., Hänninen, T., Helkala, E.-L., Vainio, P. A., & Riekkinen, P. J. (1998) · Neurobiology of Aging · doi:10.1016/s0197-4580(98)00006-2 · Cited by 265 · see citing works
Age-related decline in MRI volumes of temporal lobe gray matter but not hippocampus
Sullivan, E. V., Marsh, L., Mathalon, D. H., Lim, K. O., & Adolf Pfefferbaum, A. (1995) · Neurobiology of Aging · doi:10.1016/0197-4580(95)00074-o · Cited by 256 · see citing works
Image processing for the study of brain structure and function: problems and programs
Andreasen, N. C., Cohen, G., Harris, G., Cizadlo, T., Parkkinen, J., Rezai, K., & Swayze, V. W. (1992) · Journal of Neuropsychiatry · doi:10.1176/jnp.4.2.125 · Cited by 262 · see citing works
Jack, C. R., Wiste, H. J., Weigand, S. D., Knopman, D. S., Mielke, M. M., Vemuri, P., Lowe, V. J., Senjem, M. L., Gunter, J. L., Reyes, D. A., et al. (2015) · Brain · doi:10.1093/brain/awv283 · Cited by 252 · see citing works
“For each N + definition, we model A/N biomarker frequencies as previously reported (Jack et al., 2014b), using multinomial models to estimate the group wise frequencies as a function of age.”
MethodSelf-citationFernández, G., Effenberger, O., Vinz, B., Steinlein, O. K., Elger, C. E., Döhring, W., & Heinze, H. J. (1998) · Neurology · doi:10.1212/wnl.50.4.909 · Cited by 248 · see citing works
Tae, W., Kim, S. S., Lee, K. U., Nam, E., & Kim, K. W. (2008) · Neuroradiology · doi:10.1007/s00234-008-0383-9 · Cited by 242 · see citing works
“Right–left hippocampal asymmetry was first reported in 52 normal young Caucasian adults [16] and in 34 Asian adults [45].”
BackgroundShort-term clinical outcomes for stages of NIA-AA preclinical Alzheimer disease
Knopman, D. S., Jack, C. R., Wiste, H. J., Weigand, S. D., Vemuri, P., Lowe, V. J., Kantarci, K., Gunter, J. L., Senjem, M. L., Ivnik, R. J., et al. (2012) · Neurology · doi:10.1212/wnl.0b013e3182563bbe · Cited by 243 · see citing works
Self-citationMethods for normalization of hippocampal volumes measured with MR.
Free, S. L., Bergin, P., Fish, D. R., Cook, M. J., Shorvon, S. D., & Stevens, J. (1995) · PubMed Central · Cited by 239 · see citing works
Intracranial capacity and brain volumes are associated with cognition in healthy elderly men
MacLullich, A. M. J., Ferguson, K., Deary, I., Seckl, J., Starr, J., & Wardlaw, J. (2002) · Neurology · doi:10.1212/wnl.59.2.169 · Cited by 213 · see citing works
MRI‐Based Hippocampal Volume Measurements in Epilepsy
Jack, C. R. (1994) · Epilepsia · doi:10.1111/j.1528-1157.1994.tb05986.x · Cited by 224 · see citing works
Self-citationEvidence for Ordering of Alzheimer Disease Biomarkers
Jack, C. R. (2011) · Archives of Neurology · doi:10.1001/archneurol.2011.183 · Cited by 221 · see citing works
“52”
Self-citationKöhler, S., Black, S. E., Sinden, M., Szekely, C. A., Kidron, D., Parker, J. L., Foster, J. K., Moscovitch, M., Wincour, G., Szalai, J. P., et al. (1998) · Neuropsychologia · doi:10.1016/s0028-3932(98)00017-7 · Cited by 216 · see citing works
Hodges, J. R. (2006) · Brain · doi:10.1093/brain/awl275 · Cited by 213 · see citing works
“This pathological staging corresponded to the emergence of more sophisticated neuroimaging techniques which were able to visualize hippocampal and entorhinal atrophy in vivo (Jack et al., 1992, 1989; Fox et al., 1996b).”
BackgroundMorra, J. H., Tu, Z., Apostolova, L. G., Green, A. E., Avedissian, C., Madsen, S. K., Parikshak, N., Hua, X., Toga, A. W., Jack, C. R., et al. (2009) · Human Brain Mapping · doi:10.1002/hbm.20708 · Cited by 210 · see citing works
Self-citationThe whole-brain pattern of magnetic susceptibility perturbations in Parkinson’s disease
Acosta‐Cabronero, J., Cárdenas‐Blanco, A., Betts, M. J., Butryn, M., Valdés-Herrera, J. P., Galazky, I., & Nestor, P. J. (2016) · Brain · doi:10.1093/brain/aww278 · Cited by 199 · see citing works
“Consequently, prior to computing Parkinson’s disease versus control Wilcoxon ranksum statistics, QSM values were age-corrected using the covariance method (Jack et al., 1989).”
MethodVolumetric MRI measurements in bipolars compared with schizophrenics and healthy controls
Harvey, I., Persaud, R., Ron, M. A., Baker, G., & Murray, R. M. (1994) · Psychological Medicine · doi:10.1017/s0033291700027847 · Cited by 199 · see citing works
Volumetric Magnetic Resonance Imaging
Watson, C. E. (1997) · Archives of Neurology · doi:10.1001/archneur.1997.00550240071015 · Cited by 196 · see citing works
Zarei, M., Patenaude, B., Damoiseaux, J., Morgese, C., Smith, S. M., Matthews, P., Barkhof, F., Rombouts, S., Sanz-Arigita, E. J., & Jenkinson, M. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2009.09.001 · Cited by 199 · see citing works
“Volumes of the subcortical structures were normalized for differences in total intracranial volume among subjects by means of an analysis of covariance approach (ANOVA), using coefficients obtained from the control group (Jack et al., 1989).”
Sex Hormones and Cognition: Neuroendocrine Influences on Memory and Learning
Hamson, D. K., Roes, M., & Galea, L. A. M. (2016) · Comprehensive physiology · doi:10.1002/cphy.c150031 · Cited by 205 · see citing works
MR-based in vivo hippocampal volumetrics: 1. Review of methodologies currently employed
Geuze, E., Vermetten, E., & Bremner, J. D. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001580 · Cited by 185 · see citing works
The human hippocampus is not sexually-dimorphic: Meta-analysis of structural MRI volumes
Tan, A., Ma, W., Vira, A., Marwha, D., & Eliot, L. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2015.08.050 · Cited by 180 · see citing works
“…2.70 ± 0.40b nr nr t2:14Q74 Head et al. (2005)a Young 26/24 22.5 ICV atlas 3.62 ± 0.34 3.74 ± 0.38 3.65 ± 0.32 3.75 ± 0.35 nr nr t2:15 Old 14/36 76.5 ICV atlas 3.51 ± 0.46 3.59 ± 0.43 3.59 ± 0.49 3.64 ± 0.40 nr nr t2:16Q75 Jack et al. (1989) 27/25 30 ICV covariance 2.50 ± 0.10 2.50 ± 0.10 2.80 ±…”
MethodInfluentialKeller, S. S., Mackay, C. E., Barrick, T. R., Wieshmann, U. C., Howard, M. A., & Roberts, N. (2002) · NeuroImage · doi:10.1006/nimg.2001.1072 · Cited by 186 · see citing works
“thermore, hippocampal volume estimation in controls in the present study is consistent with previous reports of right-greater-than-left hippocampal asymmetry (Jack et al., 1989; Pfluger et al., 1999; Soninen et al., 1994).”
ResultJack, C. R., Petersen, R. C., Xu, Y. C., O’Brien, P. C., Waring, S. C., Tangalos, E. G., Smith, G. E., Ivnik, R. J., Thibodeau, S. N., & Kokmen, E. (1998) · Annals of Neurology · doi:10.1002/ana.410430307 · Cited by 187 · see citing works
Self-citationPredictive Value of Magnetic Resonance Imaging in Temporal Lobe Epilepsy Surgery
Kuzniecky, R., Burgard, S. A., Faught, E., et al. (1993) · Archives of Neurology · doi:10.1001/archneur.1993.00540010059018 · Cited by 186 · see citing works
Subfields of the hippocampal formation at 7 T MRI: In vivo volumetric assessment
Wisse, L. E. M., Gerritsen, L., Zwanenburg, J. J. M., Kuijf, H. J., Luijten, P. R., Biessels, G. J., & Geerlings, M. I. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.03.023 · Cited by 183 · see citing works
“…hippocampus proper, subiculum, and dentate gyrus, was manually outlined according to the protocol by Knoops et al. (2010) based on previously published criteria (Convit et al., 1997; Jack, 1994; Jack et al., 1989, 1997; Juottonen et al., 1999; van de Pol et al., 2007; Watson et al., 1992, 1997).”
Marseglia, A., Fratiglioni, L., Kalpouzos, G., Wang, R., Bäckman, L., & Xu, W. (2018) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2018.06.3060 · Cited by 183 · see citing works
“All MRI measurements were adjusted by total intracranial volume and age [34], and the adjusted volumeswere used in data analyses.”
MethodReder, L. M., Park, H., & Kieffaber, P. D. (2009) · Psychological Bulletin · doi:10.1037/a0013974 · Cited by 180 · see citing works
“There is ample reason to believe that working memory declines with age (e.g., Craik & Jennings, 1992; Hartman, Bolton, & Fehnel, 2001) and that the hippocampus also atrophies with age (Hedden & Gabrieli, 2004; Jack et al., 1989, 1998).”
White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer’s disease
Araque Caballero, M. Á., Suárez-Calvet, M., Duering, M., Franzmeier, N., Benzinger, T., Fagan, A. M., Bateman, R. J., Jack, C. R., Levin, J., Dichgans, M., et al. (2018) · Brain · doi:10.1093/brain/awy229 · Cited by 179 · see citing works
Self-citationAtrophy rates accelerate in amnestic mild cognitive impairment
Jack, C. R., Weigand, S. D., Shiung, M. M., Przybelski, S. A., O’Brien, P. C., Gunter, J. L., Knopman, D. S., Boeve, B. F., Smith, G. E., & Petersen, R. C. (2007) · Neurology · doi:10.1212/01.wnl.0000281688.77598.35 · Cited by 175 · see citing works
Self-citationMenke, R., Scholz, J., Miller, K. L., Deoni, S., Jbabdi, S., Matthews, P. M., & Zarei, M. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.05.017 · Cited by 175 · see citing works
“Before conducting group comparisons, volumes of each ROI were adjusted for individual variation in total brain volume using an analysis of covariance approach (Jack et al., 1989).”
Vemuri, P., Whitwell, J. L., Kantarci, K., Josephs, K. A., Parisi, J. E., Shiung, M. S., Knopman, D. S., Boeve, B. F., Petersen, R. C., Dickson, D. W., et al. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.05.012 · Cited by 172 · see citing works
Self-citationMori, E., Hirono, N., Yamashita, H., Imamura, T., Ikejiri, Y., Ikeda, M., Kitagaki, H., Shimomura, T., & Yoneda, Y. (1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.1.18 · Cited by 170 · see citing works
Nyberg, L. H., Karalija, N., Salami, A., Andersson, M., Wåhlin, A., Kaboodvand, N., Köhncke, Y., Axelsson, J., Rieckmann, A., Papenberg, G., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1606309113 · Cited by 164 · see citing works
“For within-person estimates of partial-volume effects, uncorrected gray-matter volumes and BPND were compared; otherwise, corrected regional volumes were used, from which the intracranial volume factor had been regressed out (100, 101).”
MethodWoermann, F. G., Barker, G. J., Birnie, K., Meencke, H. J., & Duncan, J. S. (1998) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.65.5.656 · Cited by 165 · see citing works
Development of the temporal lobe in infants and children: analysis by MR-based volumetry.
Utsunomiya, H., Takano, K., Okazaki, M., & Mitsudome, A. (1999) · PubMed Central · Cited by 161 · see citing works
Wolf, H., Grunwald, M., Kruggel, F., Riedel-Heller, S. G., Angerhöfer, S., Hojjatoleslami, A., Hensel, A., Arendt, T., & Gertz, H.-J. (2001) · Neurobiology of Aging · doi:10.1016/s0197-4580(00)00238-4 · Cited by 157 · see citing works
“We think that this finding most likely reflects the physiological hemispheric asymmetry of the human hippocampus which has been consistently demonstrated in a large number of studies involving healthy subjects of all age groups [5,17,20,21,27,43,48,50,54].”
Plasma cortisol levels, brain volumes and cognition in healthy elderly men.
MacLullich, A. M. J., Deary, I., Starr, J., Ferguson, K., Wardlaw, J., & Seckl, J. (2005) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2004.12.005 · Cited by 149 · see citing works
“In the posterior head of the hippocampus, an arbitrary judgment of the boundary between the hippocampus and the amygdala was made from the position of the temporal horn and the alveus or by comparing a slice with subsequent slices in which the division was more obvious (Jack et al., 1989, 1990).”
MethodThe human amygdala: a systematic review and meta-analysis of volumetric magnetic resonance imaging
Brierley, B., Shaw, P., & David, A. S. (2002) · Brain Research Reviews · doi:10.1016/s0165-0173(02)00160-1 · Cited by 156 · see citing works
Amygdalar Volume and Emotional Memory in Alzheimer’s Disease
Mori, E., Ikeda, M., Hirono, N., Kitagaki, H., Imamura, T., & Shimomura, T. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.2.216 · Cited by 154 · see citing works
Cascino, G. D., Jack, C. R., Parisi, J. E., Marsh, W. R., Kelly, P. J., Sharbrough, F. W., Hirschorn, K. A., & Trenerry, M. R. (1992) · Epilepsy Research · doi:10.1016/0920-1211(92)90021-k · Cited by 156 · see citing works
Self-citationA longitudinal study of hippocampal volume in first episode psychosis and chronic schizophrenia
Wood, S. J., Velakoulis, D., Smith, D. J., Bond, D. J., Stuart, G. W., McGorry, P. D., Brewer, W. J., Bridle, N., Eritaia, J., Desmond, P. M., et al. (2001) · Schizophrenia Research · doi:10.1016/s0920-9964(01)00175-x · Cited by 153 · see citing works
Focal posterior cingulate atrophy in incipient Alzheimer's disease
Pengas, G., Hodges, J. R., Watson, P., & Nestor, P. J. (2008) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2008.03.014 · Cited by 149 · see citing works
Bicaudate Ratio as a Magnetic Resonance Imaging Marker of Brain Atrophy in Multiple Sclerosis
Bermel, R. A., Bakshi, R., Tjoa, C. W., Puli, S. R., & Jacobs, L. R. (2002) · Archives of Neurology · doi:10.1001/archneur.59.2.275 · Cited by 148 · see citing works
“To correct caudate volume for head size, total brain volume was forced into the regression model with caudate volume as the other independent variable, based on a previously described method.(19) Statistical analysis was performed using the SPSS software package (Version 10.”
MethodAge differences in hippocampal subfield volumes from childhood to late adulthood
Daugherty, A. M., Bender, A. R., Raz, N., & Ofen, N. (2015) · Hippocampus · doi:10.1002/hipo.22517 · Cited by 149 · see citing works
“The analysis of covariance approach (Jack et al., 1989) minimizes the bias against detection of age differences whilst allowing for appropriate testing of sex differences in subcortical volumes.”
MethodJackson, J., Balota, D. A., Duchek, J. M., & Head, D. M. (2011) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2011.11.024 · Cited by 146 · see citing works
MRI-based hippocampal volumetrics: Data acquisition, normal ranges, and optimal protocol
Jack, C. R., Theodore, W. H., Cook, M. J., & McCarthy, G. (1995) · Magnetic Resonance Imaging · doi:10.1016/0730-725x(95)02013-j · Cited by 147 · see citing works
Self-citationMenke, R., Jbabdi, S., Miller, K. L., Matthews, P. M., & Zarei, M. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.05.086 · Cited by 146 · see citing works
“Before conducting group comparisons, all volumeswere adjusted for individual variation in total brain volumeusing ananalysis of covariance approach (Jack et al., 1989).”
Brain perfusion SPECT and MRI in foetal alcohol syndrome
Riikonen, R., Salonen, I., Partanen, K. P. L., & Verho, S. (1999) · Developmental Medicine & Child Neurology · doi:10.1017/s0012162299001358 · Cited by 151 · see citing works
Longitudinal MRI findings from the vitamin E and donepezil treatment study for MCI
Jack, C. R., Petersen, R. C., Grundman, M., Jin, S., Gamst, A. C., Ward, C. P., Sencakova, D., Doody, R. S., & Thal, L. J. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2007.03.004 · Cited by 142 · see citing works
“Anatomic criteria used to define the boundaries of the hippocampus and ERC have been published (Jack et al., 1989;Jack et al., 2004) Rates of change of the whole brain and ventricle were made using the boundary shift integral algorithm (BSI) (Figure 1) (Fox et al., 1997;Freeborough et al.,…”
MethodSelf-citationBetts, M. J., Acosta‐Cabronero, J., Cárdenas‐Blanco, A., Nestor, P. J., & Düzel, E. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2016.05.024 · Cited by 136 · see citing works
FDG-PET Findings in the Wernicke-Korsakoff Syndrome
Reed, L. J., Lasserson, D. S., Marsden, P. K., Stanhope, N., Stevens, T., Bello, F., Kingsley, D., Colchester, A. C. F., & Kopelman, M. D. (2003) · Cortex · doi:10.1016/s0010-9452(08)70876-1 · Cited by 144 · see citing works
Apolipoprotein E ε4 and the pattern of regional brain atrophy in Alzheimer’s disease
Hashimoto, M., Yasuda, M., Tanimukai, S., Matsui, M., Hirono, N., Kazui, H., & Mori, E. (2001) · Neurology · doi:10.1212/wnl.57.8.1461 · Cited by 143 · see citing works
Hippocampal head atrophy after traumatic brain injury
Ariza, M., Serra-Grabulosa, J. M., Junqué, C., Ramírez, B., Mataró, M., Poca, M. A., Bargalló, N., & Sahuquillo, J. (2005) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2005.11.007 · Cited by 143 · see citing works
Schuff, N. W., Amend, D. L., Knowlton, R. K., Norman, D. M., Fein, G., & Weiner, M. W. (1999) · Neurobiology of Aging · doi:10.1016/s0197-4580(99)00022-6 · Cited by 141 · see citing works
Mori, E., Yoneda, Y., Yamashita, H., Hirono, N., Ikeda, M., & Yamadori, A. (1997) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.63.2.214 · Cited by 140 · see citing works
- Authors
- Jack, C. R., Twomey, C. K., Zinsmeister, A. R., Sharbrough, F. W., Petersen, R. C., & Cascino, G. D.
- Affiliations
- Mayo Clinic (US)
- Venue
- Radiology
- Published
- 1989-08
- Volume
- 172
- Issue
- 2
- Pages
- 549-554
- ISSN
- 0033-8419 (ISSN-L)
- 1527-1315
- OpenAlex
- W2015896685
- Cited by
- 592
- References
- 0
- Citations by year
- 2026: 7 · 2025: 10 · 2024: 14 · 2023: 17 · 2022: 19 · 2021: 16 · 2020: 17 · 2019: 16 · 2018: 17 · 2017: 24 · 2016: 25 · 2015: 31 · 2014: 14 · 2013: 19 · 2012: 23
- FWCI
- 5.85
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Radiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hemispheric Asymmetry in Neuroscience
- Health Sciences › Medicine › Anatomy › Medical and Biological Sciences
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
- Keywords
- anterior temporal lobe, hippocampal formation, brain volume, left-right asymmetry, handedness, age effects, sex effects, young adults
- MeSH terms
- Adult, Age Factors, Female, Hippocampus, Humans, Functional Laterality, Magnetic Resonance Imaging, Male, Reference Values, Sex Factors, Temporal Lobe
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
