Autopoiesis: The organization of living systems, its characterization and a model
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Network models such as autopoiesis, which provide only qualitative definitions without explicit kinetics, are inadequate for homeostasis-related scrutiny.
“Network models such as autopoiesis [33,34], which provide only qualitative definitions without explicit kinetics are inadequate for homeostasis-related scrutiny.”
From Systems protobiology: origin of life in lipid catalytic networks (2018) · cites this paper as [33]
Self-organizing agents maintain their existence by creating a boundary that separates their internal states from the external states of their environment.
“Self-organizing agents maintain their existence by creating a boundary that separates their internal states from the external states of their environment [12,25,18,15].”
From Reactive Environments for Active Inference Agents with RxEnvironments.jl (2025) · cites this paper as [25]
A cell persists by creating and maintaining a boundary through which it interacts with the environment, thereby maintaining the integrity of the boundary.
“For example, a cell persists in virtue of its ability to create and maintain a boundary (cell-surface), through which it interacts with the environment, thereby maintaining the integrity of the boundary.”
From From cognitivism to autopoiesis: towards a computational framework for the embodied mind (2018) · cites this paper as Varela et al. 1974
Autopoiesis, or self-creation, enables a system to limit the possible states it visits and thus to survive.
“It is this autopoiesis, or self-creation, which enables the system to limit the possible states it visits, and thus to survive (Varela et al. 1974).”
From From cognitivism to autopoiesis: towards a computational framework for the embodied mind (2018) · cites this paper as Varela et al. 1974
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“Interactions between elements of an autopoietic system regulate the production and regeneration of the system’s components, having the potential to develop, preserve, and produce their own organization (Varela et al., 1974).”
BackgroundReactive Environments for Active Inference Agents with RxEnvironments.jl
Nuijten, W. W. L., & de Vries, B. (2025) · Communications in computer and information science · doi:10.1007/978-3-031-77138-5_10
“Self-organizing agents maintain their existence by creating a boundary that separates their internal states from the external states of their environment [12,25,18,15].”
- Authors
- Varela, F. G., Maturana, H. R., & Uribe, R.
- Affiliations
- University of Chile (CL)
- Venue
- Biosystems
- Publisher
- Elsevier BV
- Published
- 1974-05
- Volume
- 5
- Issue
- 4
- Pages
- 187-196
- ISSN
- 0303-2647 (ISSN-L)
- OpenAlex
- W2093020640
- Cited by
- 1,899
- References
- 5
- Citations by year
- 2026: 63 · 2025: 59 · 2024: 71 · 2023: 111 · 2022: 90 · 2021: 89 · 2020: 132 · 2019: 70 · 2018: 73 · 2017: 68 · 2016: 69 · 2015: 60 · 2014: 67 · 2013: 83 · 2012: 64
- FWCI
- 3.38
- Type
- journal article
- Language
- en
- Open access
- Licence
- cc-by-nc-nd
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- Locations
- Biosystems (publishedVersion)
- PubMed (publishedVersion)
- Universidad de Chile (submittedVersion, cc-by-nc-nd)
- Topics
- Physical Sciences › Physics and Astronomy › Statistical and Nonlinear Physics › Complex Systems and Dynamics
- Social Sciences › Arts and Humanities › History and Philosophy of Science › Philosophy and History of Science
- Physical Sciences › Computer Science › Computational Theory and Mathematics › Cellular Automata and Applications
- Keywords
- autopoiesis, biological systems, autopoietic systems, computer simulation model
- MeSH terms
- Origin of Life, Biological Evolution, Models, Biological
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