Cited by 175Cardiovascular Effects of ExerciseCardiovascular and exercise physiologyCardiovascular Function and Risk Factors

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Different effects of prolonged exercise on the right and left ventricles

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Douglas, Pamela S., O'Toole, Mary L., Miller, W.Douglas B., Reichek, Nathaniel·1990·Journal of the American College of Cardiology

DOI 10.1016/0735-1097(90)90176-p

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Abstract

To examine the functional consequences of the greater increase in right ventricular work with exercise, the effects of prolonged exercise on the right and left heart chambers were compared in 41 athletes before, at the finish (13 min) and after recovery (28 h) from the Hawaii Ironman Triathlon (3.9 km swim, 180.2 km bike ride, 42.2 km run). Two-dimensional and Doppler echocardiograms were analyzed for left and right atrial and ventricular areas at end-diastole and end-systole, right and left ventricular inflow velocities and mitral and tricuspid regurgitation. After exercise, left ventricular and left and right atrial sizes were reduced, whereas right ventricular size increased (diastole: 21.4 to 24.2 cm2; systole: 15.8 to 18.2 cm2; p less than 0.01). The emptying fraction of all chambers was unchanged. Left but not right ventricular inflow showed an increase in peak velocity of rapid filling, whereas both atrial systolic velocities increased (26 to 38 cm/s tricuspid; 38 to 54 cm/s mitral; both p less than 0.01). Overall, the right ventricular early to atrial velocity ratio was reduced after exercise (1.56 to 1.17; p less than 0.05) and the left ventricular pattern was unchanged. The prevalence of tricuspid regurgitation was statistically unchanged (86% to 52%), although that of mitral regurgitation was greatly reduced (76% to 0%). Changes in all variables returned toward prerace values during recovery. Thus, in highly trained athletes, prolonged exercise causes differing responses of the right and left ventricles. These differences may be due to changes in right ventricular function, shape or compliance.

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Authors: Douglas, P. S., O'Toole, M. L., Miller, W. D. B., & Reichek, N.
Affiliations: Hospital of the University of Pennsylvania (US)
Baptist Memorial Hospital (US)
Corresponding author: Douglas, Pamela S.
ORCID: Douglas, Pamela S.
Venue: Journal of the American College of Cardiology
Publisher: Elsevier BV
Published: 1990-01
Volume: 15
Issue: 1
Pages: 64-69
ISSN: 0735-1097 (ISSN-L)
DOI: 10.1016/0735-1097(90)90176-p
OpenAlex: W2077549315
Cited by: 172
References: 25
Citations by year: 2026: 1 · 2025: 1 · 2024: 2 · 2023: 3 · 2022: 4 · 2021: 2 · 2020: 6 · 2019: 3 · 2018: 4 · 2017: 10 · 2016: 3 · 2015: 12 · 2014: 13 · 2013: 7 · 2012: 9
FWCI: 1.53
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 8597 d)
Locations: Journal of the American College of Cardiology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
Keywords: prolonged exercise, right ventricle, left ventricle, right ventricular hypertrophy, athletes, triathlon, cardiac chamber dimensions, mitral regurgitation, tricuspid regurgitation, post-exercise recovery, right ventricular compliance, echocardiography
MeSH terms: Adult, Bicycling, Coronary Circulation, Echocardiography, Physical Exertion, Female, Humans, Male, Myocardial Contraction, Physical Endurance, Running, Stroke Volume, Swimming, Echocardiography, Doppler, Ventricular Function

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Different effects of prolonged exercise on the right and left ventricles

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