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Cited by 550Mitochondrial Function and PathologyRedox biology and oxidative stressAutophagy in Disease and Therapy

The DOI matches its Crossref record; 218 of the 218 references it cites were found in a registry or an index.

Mitochondrial mutations may increase oxidative stress: Implications for carcinogenesis and aging?

Bandy, Brian, Davison, Allan J.·1990·Free Radical Biology and Medicine
DOI 10.1016/0891-5849(90)90152-9
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Abstract

The sensitivity of mitochondrial DNA to damage by mutagens predisposes mitochondria to injury on exposure of cells to genotoxins or oxidative stress. Damage to the mitochondrial genome causing mutations or loss of mitochondrial gene products, or to some nuclear genes encoding mitochondrial membrane proteins, may accelerate release of reactive species of oxygen. Such aberrant mitochondria may contribute to cellular aging and promotion of cancer.

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Crossref · 10.1016/0891-5849(90)90152-9

Cites

218 of 218 references verified0 citation errors · 0 not checkable

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Citations

Cites

Show all 218 references

Research works printed but not linked: 17

  1. Miquel, 1983, An integrated theory of cell organismic aging as the result of mitochondrial differentiation and intrinsic mt DNA mutagenesis, Age, 6, 145
  2. Nagatani, 1960, Cytological studies on the affinity of the carcinogenic azo dyes for cytoplasmic components, Int. Rev. Cytol., 10, 243
  3. Rossi, 1988, The carcinogen chromium(VI) targets mitochondrial-DNA, Abstracts Of Papers Of The American Chemical Society, 195, 407
  4. Welter, 1988, Observation of mitochondrial DNA in malignant human tumors, J. Exp. Clin. Cancer Res, 7, 13
  5. Howell, 1987, Mutational analysis of the mitochondrialcytochrome b gene, In Vitro Cell. Dev. Biol., 23, 73A
  6. Coon, 1979, Tumorigenicity of cybrids, J. Cell. Biol., 83, 499A
  7. Israel, 1982, Cytoplasmic hybrids (cybrids) and reconstructed cells between normal and tumorigenetic rat liver cells: suppression of the tumorigenic phenotype, In Vitro, 18, 284A
  8. Wallace, 1987, Mitochondrial genes and cancer, In Vitro Cell. Develop. Biol., 23, A73
  9. Forman, 1980, The role of unbisemiquinone in superoxide production by dihydroorate dehydrogenase: a proposed mechanism, Vol. 1, 76
  10. Linnane, 1956, A re-examination of some problems of “petite” yeast, Australian J. Sci., 18, 165
  11. Boveris, 1980, Production of superoxide anion by the NADH-dehydrogenase of mammalian mitochondria, Vol. 1, 84
  12. Slater, 1983, The Q cycle, an ubiquitous mechanisms of electron transfer, TIBS, 7, 239
  13. Autor, 1982, Regulation of manganese superoxide dismutase by oxygen in Saccahromyces cerevisiae, Biochem. Soc. Trans. actions, 10, 78
  14. Smith, 1984, Free radical-induced changes in the surface morphology of isolated hepatocytes, Vol. 27, 103
  15. Chambers, 1980, Fertilization and cleavage of eggs of the sea urchin Letechius variegatus in Ca2+-free sea water, Eur. J. Cell Biol., 22, 476
  16. Cheeseman, 1986, Studies on lipid peroxidation in normal and tumour tissues, Biochem. J., 235, 504
  17. Szent-Gyorgi, 1967, Ketoaldehydes and cell division, Science, 155, 539

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Metadata

Authors
Bandy, B., & Davison, A. J.
Affiliations
Simon Fraser University (CA)
Corresponding author
Bandy, Brian
Venue
Free Radical Biology and Medicine
Publisher
Elsevier BV
Published
1990
Volume
8
Issue
6
Pages
523-539
ISSN
0891-5849 (ISSN-L)
DOI
10.1016/0891-5849(90)90152-9
OpenAlex
W2048339025
Cited by
550
References
218
Citations by year
2026: 4 · 2025: 3 · 2024: 8 · 2023: 2 · 2022: 12 · 2021: 5 · 2020: 10 · 2019: 4 · 2018: 7 · 2017: 13 · 2016: 19 · 2015: 17 · 2014: 26 · 2013: 22 · 2012: 20
FWCI
6.70
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Free Radical Biology and Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Mitochondrial Function and Pathology
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Autophagy in Disease and Therapy
Keywords
mitochondrial DNA mutations, oxidative stress, carcinogenesis, cellular aging, reactive oxygen species, genotoxins, mitochondrial membrane proteins, mitochondrial dysfunction
MeSH terms
Aging, Animals, DNA, Mitochondrial, Humans, Mitochondria, Mutation, Neoplasms, Oxygen

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