Cited by 78Neuroendocrine regulation and behaviorNeuropeptides and Animal PhysiologyElectrolyte and hormonal disorders

Distribution and developmental change of vasopressin V1A and V2 receptor mRNA in rats

Hirasawa, Akira, Hashimoto, Keitaro, Tsujimoto, Gozoh·1994·European Journal of Pharmacology Molecular Pharmacology

Abstract

With the reverse transcription-polymerase chain reaction (RT-PCR) method, we examined the tissue distribution of vasopressin V1A and V2 receptor transcripts in newborn and adult rats. In adult rats, vasopressin V1A receptor mRNA was detected in the brain, lung, liver and kidney, whereas vasopressin V2 receptor mRNA was found only in the kidney. In newborn rats, vasopressin V1A receptor mRNA was detected in the brain, liver, heart and kidney, whereas vasopressin V2 receptor mRNA in the kidney and brain. In the newborn rat brain the level of vasopressin V2 receptor mRNA decreased with age, and could not be detected in rats older than 2 weeks. Our results first demonstrated the extrarenal expression of vasopressin V2 receptor in the newborn rat brain. Also, the study showed that expressions of vasopressin V1A and V2 receptor mRNA transcripts are dynamically altered in the process of development.

Integrity signals

Registry

Crossref · 10.1016/0922-4106(94)90226-7

Cites

18 of 18 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Hirasawa, A., Hashimoto, K., & Tsujimoto, G.
Affiliations
University of Yamanashi (JP)
Corresponding author
Tsujimoto, Gozoh
Venue
European Journal of Pharmacology Molecular Pharmacology
Publisher
Elsevier BV
Published
1994-03
Volume
267
Issue
1
Pages
71-75
ISSN
0922-4106 (ISSN-L)
OpenAlex
W2051433145
Cited by
78
References
18
Citations by year
2026: 1 · 2024: 3 · 2023: 1 · 2022: 3 · 2021: 1 · 2019: 2 · 2018: 6 · 2017: 2 · 2015: 1 · 2014: 3 · 2013: 6 · 2012: 1
FWCI
5.92
Type
journal article
Language
en
Open access
closed
Locations
  • European Journal of Pharmacology Molecular Pharmacology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Electrolyte and hormonal disorders
Keywords
vasopressin V1a receptor, V2 receptor, receptor mRNA expression, tissue distribution, developmental changes, neonatal rats, brain, kidney, age-related gene expression
MeSH terms
Age Factors, Animals, Animals, Newborn, Base Sequence, Female, Male, Molecular Sequence Data, RNA, Messenger, Polymerase Chain Reaction, Rats, Sprague-Dawley, Receptors, Vasopressin, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review