The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Is the multidrug transporter a flippase?
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Citations
Cites
THE BIOCHEMISTRY OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG RESISTANCE
Endicott, J. A., & Ling, V. (1989) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.58.070189.001033 · Cited by 2,071
Hyde, S. C., Emsley, P., Hartshorn, M. J., Mimmack, M. M., Gileadi, U., Pearce, S. R., Gallagher, M. P., Gill, D. R., Hubbard, R. E., & Higgins, C. F. (1990) · Nature · doi:10.1038/346362a0 · Cited by 1,145
Self-citationStatic and dynamic lipid asymmetry in cell membranes
Devaux, P. F. (1991) · Biochemistry · doi:10.1021/bi00219a001 · Cited by 827
Isolation and expression of a complementary DNA that confers multidrug resistance
Gros, P., Neriah, Y. B., Croop, J. M., & Housman, D. E. (1986) · Nature · doi:10.1038/323728a0 · Cited by 797
A protein-conducting channel in the endoplasmic reticulum
Simon, S. M., & Blobel, G. (1991) · Cell · doi:10.1016/0092-8674(91)90455-8 · Cited by 619
Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells.
Kuchler, K., Sterne, R. E., & Thorner, J. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb08580.x · Cited by 442
Reduced drug accumulation in multiply drug-resistant human KB carcinoma cell lines.
Fojo, A. T., Akiyama, S., Gottesman, M. M., et al. (1985) · PubMed · Cited by 435
Self-citationPhotosensitized labeling of a functional multidrug transporter in living drug-resistant tumor cells.
Raviv, Y., Pollard, H. B., Bruggemann, E. P., Pastan, I., & Gottesman, M. M. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)39690-5 · Cited by 387
Self-citationHamada, H., & Tsuruo, T. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)57324-0 · Cited by 332
Issartel, J.-P., Koronakis, V., & Hughes, C. (1991) · Nature · doi:10.1038/351759a0 · Cited by 311
Cited by
ABC Transporters: From Microorganisms to Man
Higgins, C. F. (1992) · Annual Review of Cell Biology · doi:10.1146/annurev.cb.08.110192.000435 · Cited by 3,985
Self-citationSmit, J. J. M., Schinkel, A. H., Elferink, R. P. J. O., Groen, A. K., Wagenaar, E., van Deemter, L., Mol, C. A. A. M., Ottenhoff, R., van der Lugt, N. M. T., van Roon, M. A., et al. (1993) · Cell · doi:10.1016/0092-8674(93)90380-9 · Cited by 1,456
Pathophysiologic Implications of Membrane Phospholipid Asymmetry in Blood Cells
Zwaal, R. F. A., & Schroit, A. J. (1997) · Blood · doi:10.1182/blood.v89.4.1121 · Cited by 1,340
Multidrug efflux pumps of gram-negative bacteria
Nikaido, H. (1996) · Journal of Bacteriology · doi:10.1128/jb.178.20.5853-5859.1996 · Cited by 1,082
Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance
Marzolini, C. (2004) · Clinical Pharmacology & Therapeutics · doi:10.1016/j.clpt.2003.09.012 · Cited by 895
Metadata
- Authors
- Higgins, C. F., & Gottesman, M. M.
- Venue
- Trends in Biochemical Sciences
- Publisher
- Elsevier BV
- Published
- 1992-01
- Volume
- 17
- Issue
- 1
- Pages
- 18-21
- ISSN
- 0968-0004 (ISSN-L)
- OpenAlex
- W2090841445
- Cited by
- 722
- References
- 19
- FWCI
- 3.83
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Is the multidrug transporter a flippase? https://app.cochat.ai/papers/10.1016/0968-0004(92)90419-a
- The paper
- Higgins, C. F., & Gottesman, M. M. (1992). Is the multidrug transporter a flippase? Trends in Biochemical Sciences. https://doi.org/10.1016/0968-0004(92)90419-a
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
