The DOI matches its Crossref record; 695 of the 703 references it cites were found in a registry or an index.
Polysaccharides of the red algae
Abstract
Red algae (Rhodophyta) are known as the source of unique sulfated galactans, such as agar, agarose, and carrageenans. The wide practical uses of these polysaccharides are based on their ability to form strong gels in aqueous solutions. Gelling polysaccharides usually have molecules built up of repeating disaccharide units with a regular distribution of sulfate groups, but most of the red algal species contain more complex galactans devoid of gelling ability because of various deviations from the regular structure. Moreover, several red algae may contain sulfated mannans or neutral xylans instead of sulfated galactans as the main structural polysaccharides. This chapter is devoted to a description of the structural diversity of polysaccharides found in the red algae, with special emphasis on the methods of structural analysis of sulfated galactans. In addition to the structural information, some data on the possible use of red algal polysaccharides as biologically active polymers or as taxonomic markers are briefly discussed.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Sulfated galactans such as agar, agarose and carrageenans usually contain repeating disaccharides of β-(1→3)-linked and α-(1→4)-linked galactopyranosyl (Galp) residues.”
From Anticancer and Cancer Preventive Properties of Marine Polysaccharides: Some Results and Prospects (2013) · cites this paper as [92]
Citations
Cites
A simple and rapid method for the permethylation of carbohydrates
Ciucanu, I., & Kerek, F. (1984) · Carbohydrate Research · doi:10.1016/0008-6215(84)85242-8 · Cited by 3,581
Hakomori, S. (1964) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a127869 · Cited by 2,144
Phillips, G. O., & Williams, P. A. (2009) · Woodhead Publishing Limited eBooks · doi:10.1533/9781845695873 · Cited by 2,129
Food Polysaccharides and Their Applications
BeMiller, J. N. (1996) · Trends in Food Science & Technology · doi:10.1016/0924-2244(96)81250-7 · Cited by 1,683
Food Polysaccharides and Their Applications
Stephen, A. M., & Phillips, G. O. (2010) · CRC Press eBooks · doi:10.1201/9781420015164 · Cited by 1,653
A note on the determination of the ester sulphate content of sulphated polysaccharides
Dodgson, K. S., & Price, R. (1962) · Biochemical Journal · doi:10.1042/bj0840106 · Cited by 1,645
Carbon-13 Nuclear Magnetic Resonance Spectroscopy of Monosaccharides
Bock, K., & Pedersen, C. M. (1983) · Advances in carbohydrate chemistry and biochemistry · doi:10.1016/s0065-2318(08)60055-4 · Cited by 1,417
Carrageenans: Biological properties, chemical modifications and structural analysis – A review
Campo, V. L., Kawano, D. F., da Silva, D. B., & Carvalho, I. (2009) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2009.01.020 · Cited by 1,412
Phillips, G. O. 1.-2., & Williams, P. A. (2020) · Elsevier eBooks · doi:10.1016/c2018-0-04245-0 · Cited by 1,402
Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate
Chen, Y., Maguire, T., Hileman, R. E., Fromm, J. R., Esko, J. D., Linhardt, R. J., & Marks, R. M. (1997) · Nature Medicine · doi:10.1038/nm0897-866 · Cited by 1,064
Research works printed but not linked: 80
- Araki, 1937, Agar-agar. III. Acetylation of the agar-like substance of Gelidium amansii L., J. Chem. Soc. Jpn., 58, 1338
- Yarotsky, 1977, Analysis of 13C-NMR spectra of some red seaweed galactans, Sov. J. Bioorg. Chem., 3, 840
- Rees, 1982, Shapes and interactions of carbohydrate chains, Vol. 1, 195
- Marchessault, 1983, Cellulose, Vol. 2, 11
- Usov, 1978, Polysaccharides of algae. 23. Polysaccharides of the red alga Bangia fuscopurpurea (Dillw.) Lyngb., Sov. J. Bioorg. Chem., 4, 51
- Usov, 1978, Polysaccharides of algae. 22. Polysaccharide composition of Rhodymenia stenogona Perest. and use of carbon-13 nmr spectroscopy for determining the structure of xylans, Sov. J. Bioorg. Chem., 4, 44
- Usov, 1974, Polysaccharides of algae. 14. Isolation of sulfated mannan and neutral xylan from the red alga Nemalion vermiculare, Zh. Obshch. Khim., 44, 416
- Usov, 1981, Polysaccharides of algae. 32. Polysaccharides of the red seaweed Galaxaura squalida Kjellm, Sov. J. Bioorg. Chem., 7, 692
- Usov, 1975, Polysaccharides of algae. 20. Studies on odonthalan, a sulfated polysaccharide from the red alga Odonthalia corymbifera (Gmel.) J.Ag., Sov. J. Bioorg. Chem., 1, 693
- Stancioff, 1969, Infrared and chemical studies on algal polysaccharides, Proc. Int. Seaweed Symp., 6, 595
- Mollion, 1986, Isolation of a new type of carrageenan from Rissoella verruculosa (Bert.) J. Ag. (Rhodophyta, Gigartinales), Bot. Mar., 29, 549
- BeMiller, 1965, Agar. Preparation of agar and agarose; methanolysis; mercaptolysis, Methods, Carbohydr. Chem., 5, 65
- Painter, 1965, Kappa-Carrageenan. Isolation of κ-carrageenan from red algae, Methods Carbohydr. Chem., 5, 98
- Araki, 1937, Agar-agar. I. Chemical changes in the process of preparation of agar-agar, J. Chem. Soc. Jpn., 58, 1085
- Usov, 1979, Polysaccharides of algae. 29. Agar composition in different generations of Gracilaria verrucosa (Huds.) Papenf., Sov. J. Bioorg. Chem., 5, 1219
- Usov, 1990, Polysaccharides of algae. 42. Composition and properties of agars from the Black Sea red seaweeds Gracilaria verrucosa (Huds.) Papenf. f. procerima and Gracilaria dura (Ag.) J. Ag., Sov. J. Bioorg. Chem., 16, 885
- Araki, 1938, Agar-agar VII l-Galactose and its derivatives, J. Chem. Soc. Jpn., 59, 424
- Araki, 1937, Agar-agar. II. Agar-like substance of Gelidium amansii L., J. Chem. Soc. Jpn., 58, 1214
- Hirase, 1972, The presence of pyruvate residues in λ-carrageenan and a similar polysaccharide, Bull. Inst. Chem. Res. Kyoto Univ., 50, 332
- Araki, 1944, Chemical studies on agar-agar. XIV. Investigation of component sugars of agar-agar by methanolysis. 1. Separation of 3,6-anhydro-l-galactose dimethylacetal, J. Chem. Soc. Jpn., 65, 725
- Kochetkov, 1970, Polysaccharides of algae. 4. Fractionation and methanolysis of a sulfated polysaccharide from Laingia pacifica Yamada, Zh. Obshch. Khim., 40, 2469
- Usov, 1971, Polysaccharides of algae. 7. Preliminary investigation of polysaccharides of the red alga Rhodomela larix (Turn.) C.Ag., Zh. Obshch. Khim., 41, 1154
- Usov, 1991, Quantitative determination of 3,6-anhydrogalactose derivatives and partial fragmentation of the red algal galactans under reductive hydrolysis conditions, Bioorg. Khim., 17, 839
- Araki, 1944, Chemical studies on agar-agar. XIII. 1. Separation of agarobiose from the agar-agar-like substance of Gelidium amansii by partial hydrolysis, J. Chem. Soc. Jpn., 65, 533
- Usov, 1981, Identification of 3,6-anhydrogalactose derivatives as N-phenylosotriazoles, Sov. J. Bioorg. Chem., 7, 752
- Usov, 1985, Identification of various cleavage products of red seaweed galactans in the form of pyridylamino derivatives, Sov. J. Bioorg. Chem., 11, 596
- Usov, 1989, Elashvili, Specific fragmentation of red algal galactans under reducing conditions, F. E. C. S. Fifth Int. Conf. Chem. Biotechnol. Biol. Active Nat. Prod. Conf. Proc. Bulgarian Acad. Sci., 2, 346
- Usov, 1992, Polysaccharides of algae. 46. Studies on agar from the red seaweed Gelidiella acerosa, Sov. J. Bioorg. Chem., 18, 588
- Kochetkov, 1971, Polysaccharides of algae. 8. Acetolysis of λ-polysaccharide from Tichocarpus crinitus (Gmel.) Rupr., Zh. Obshch. Khim., 41, 1160
- Usov, 1978, Polysaccharides of algae. 27. Partial acetolysis of the sulfated galactan from the red seaweed Grateloupia divaricata Okam, Sov. J. Bioorg. Chem., 4, 814
- Painter, 1959, Isolation of sulphated sugars from some algal polysaccharides, Chem. Ind., 1488
- Kochetkov, 1973, Polysaccharides of algae. 12. Partial hydrolysis of a polysaccharide from Laingia pacifica Yamada, Zh. Obshch. Khim., 43, 1832
- Kochetkov, 1967, Polysaccharides of algae. 1. Water-soluble polysaccharides of the red seaweed Laingia pacifica, Zh. Obshch. Khim., 37, 792
- Usov, 1975, Solvolytic desulfation of dextran sulfate, Sov. J. Bioorg. Chem., 1, 506
- Usov, 1972, Polysaccharides of algae. 9. Solvolytic desulfation of a polysaccharide from the red seaweed Laingia pacifica Yamada, Zh. Obshch. Khim., 42, 945
- Takano, 1998, Specific 6-O-desulfation of heparin, Carbohydr. Lett., 3, 71
- Araki, 1937, Agar-agar. V. d-Galactose and its derivatives, J. Chem. Soc. Jpn., 58, 1362
- Usov, 1981, Polysaccharides of algae. 30. Methylation of κ-carrageenan type polysaccharides of the red seaweeds Tichocarpus crinitus (Gmel.) Rupr., Furcellaria fastigiata (Huds.) Lam. and Phyllophora nervosa (De Cand.) Grev., Sov. J. Bioorg. Chem., 7, 222
- Kochetkov, 1972, Polysaccharides of algae. 11. Methylation analysis of a polysaccharide from Laingia pacifica Yamada, Zh. Obshch. Khim., 42, 2309
- Hakomori, 1964, Rapid permethylation of glycolipids and polysaccharides, catalyzed by methylsulfinyl carbanion in dimethyl sulfoxide, J. Biochem., 55, 205
- Usov, 1969, Polysaccharides of algae. 3. Isolation and preliminary investigation of a λ-polysaccharide from Tichocarpus crinitus (Gmel.) Rupr., Zh. Obshch. Khim., 39, 905
- Barbakadze, 1978, Polysaccharides of algae. 26. Methylation and periodate oxidation of a polysaccharide from the red seaweed Grateloupia divaricata Okam., Sov. J. Bioorg. Chem., 4, 808
- Aspinall, 1982, Chemical characterization and structure determination of polysaccharides, Vol. 1
- Usov, 1996, Polysaccharides of algae. 49. Isolation of alginate, sulfated xylogalactan, and floridean starch from calcareous red alga Bossiella cretacea (P. et R.) Johansen (Rhodophyta, Corallinaceae), Russ. J. Bioorg. Chem., 22, 106
- Usov, 1972, Polysaccharides of algae. 10. Periodate oxidation of a polysaccharide from Laingia pacifica Yamada, Zh. Obshch. Khim., 42, 1623
- Usov, 1968, Polysaccharides of algae. 2. Polysaccharides of the red seaweed Odonthalia corymbifera (Gmel.) J. Ag. Isolation of 6-O-methyl-d-galactose, Zh. Obshch. Khim., 38, 234
- Usov, 1975, Polysaccharides of algae. 19. Partial methanolysis of sulfated polysaccharides of the red alga Rhodomela larix (Turn.) C.Ag., Sov. J. Bioorg. Chem., 1, 511
- Usov, 1997, Elashvili, Polysaccharides of algae. 51. Partial reductive hydrolysis of a sulfated galactan from the red alga Laurencia coronopus J.Ag. (Rhodophyta, Rhodomelaceae), Russ. J. Bioorg. Chem., 23, 468
- Bhattacharjee, 1979, Spectroscopic analysis of agar-type polysaccharides, Vol. 1, 645
- Welty, 1977, Carrageenans. Part 12. The 300 MHz proton magnetic resonance spectra of methyl β-d-galactopyranoside, methyl 3,6-anhydro-α-d-galactopyranoside, agarose, κ-carrageenan, and segments of ι-carrageenan and agarose sulphate, J. Chem. Res.
- Shashkov, 1977, Carbon-13 NMR spectra of methyl 3,6-anhydro-α-d-galactopyranoside and its methyl ethers, Sov. J. Bioorg. Chem., 3, 35
- Usov, 1977, Synthesis of methyl 3-O-methyl- and 3,6-di-O-methyl-β-d-galactopyranosides, Sov. J. Bioorg. Chem., 3, 554
- Usov, 1978, Polysaccharides of algae. 28. Application of 13C-NMR spectroscopy for structural studies of galactan from the red seaweed Grateloupia divaricata Okam., Sov. J. Bioorg. Chem., 4, 1085
- Shashkov, 1981, Determination of the absolute configuration of sugars in oligo- and polysaccharides using glycosylation effects in 13C-NMR spectra, Sov. J. Bioorg. Chem., 7, 746
- Shashkov, 1978, Polysaccharides of algae. 24. Application of 13C-NMR spectroscopy for structural analysis of polysaccharides of the agar group, Sov. J. Bioorg. Chem., 4, 57
- Yarotsky, 1978, Polysaccharides of algae. 25. Application of 13C-NMR spectroscopy for structural analysis of κ-carrageenan group polysaccharides,, Sov. J. Bioorg. Chem., 4, 537
- Kochetkov, 1992, A programme SCAN for the 13C NMR-based structural analysis of linear polysaccharides using personal computer, Bioorg. Khim., 18, 116
- Miller, 2001, The structure of the carrageenan extracted from the tetrasporophytic form of Stenogramme interrupta as determined by 13C NMR spectroscopy, Bot. Mar., 44, 583
- Yaphe, 1966, The purification and properties of an agarase from a marine bacterium, Pseudomonas atlantica, Proc. Int. Seaweed Symp., 5, 333
- Duckworth, 1969, Specificity studies on the agarase from a Cytophaga species, Proc. Int. Seaweed Symp., 6, 435
- Usov, 1981, Polysaccharides of algae. 31. Enzymic hydrolysis of agar-like polysaccharide from the red seaweed Rhodomela larix (Turn.) C. Ag, Sov. J. Bioorg. Chem., 7, 572
- Benitez, 1979, Partial purification of a carrageenase from the tropical sea urchin Diadema setosum, Proc. Int. Seaweed Symp., 9, 353
- Greer, 1984, Characterization of hydrid (beta-kappa-gamma) carrageenan from Eucheuma gelatinae J. Agardh (Rhodophyta, Solieriaceae) using carrageenases, infrared and 13C-nuclear magnetic resonance spectroscopy, Bot. Mar., 27, 473, 10.1515/botm.1984.27.10.473 · DOI
- Johnston, 1969, Immunochemistry of carrageenans, Proc. Int. Seaweed Symp., 6, 507
- Gretz, 1991, Ultrastructural immunogold localization of carrageenan in the Golgi complex of Agardhiella subulata, J. Phycol., 27, 26
- Lapshina, 1991, Agar from the unattached form of Gracilaria verrucosa (Huds.) Papenf. of Primorski territory, Bioorg. Khim., 17, 1494
- Usov, 1974, Polysaccharides of algae. 13. Monosaccharide composition of polysaccharides of several red algae from the Japan Sea, Zh. Obshch. Khim., 44, 191
- Miller, 1982, Agars from New Zealand red algae in the family Gelidiaceae: A structural study, N. Z. J. Sci., 25, 15
- Usov, 1989, Polysaccharides of algae. 41. Characterization of water-soluble polysaccharides from several representatives of the genus Laurencia (Ceramiales, Rhodophyta), Sov. J. Bioorg. Chem., 15, 701
- Usov, 1989, Polysaccharides of algae. 39. Study on sulfated galactan from the red seaweed Palmaria stenogona Perest, Sov. J. Bioorg. Chem., 15, 111
- Usov, 1998, Polysaccharides of algae. 52. The structure of sulfated xylogalactan from the calcareous red alga Bossiella cretacea (P. et R.) Johansen (Rhodophyta, Corallinales), Russ. J. Bioorg. Chem., 24, 123
- Waaland, 1973, Experimental studies on propagation of Iridaea and Gigartina, J. Phycol., 9, 12
- McCandless, 1982, Carrageenan patterns in the Phyllophoraceae, Biochem. Syst. Ecol., 10, 275
- Miller, 1998, The structure of a pyruvylated carrageenan extracted from Stenogramme interrupta as determined by 13C NMR spectroscopy, Bot. Mar., 41, 305, 10.1515/botm.1998.41.1-6.305 · DOI
- Usov, 1975, Polysaccharides of algae. 16. Study of the structure of the sulfated mannan from the red alga Nemalion vermiculare Sur., Zh. Obshch. Khim., 45, 916
- Usov, 1975, Polysaccharides of algae. 18. Acetolysis of sulfated mannan from Nemalion vermiculare Sur., Zh. Obshch. Khim., 45, 1377
- Usov, 1975, Polysaccharides of algae. 21. Alkaline degradation of sulfated mannan from the red alga Nemalion vermiculare Sur, Sov. J. Bioorg. Chem., 1, 700
- Usov, 1975, Synthesis and carbon-13 NMR spectra of methyl 3-O-methyl-α-d-mannopyranoside sulphates, Sov. J. Bioorg. Chem., 1, 1137
- Usov, 1988, Polysaccharides of algae. 38. Polysaccharide composition of the red seaweed Liagora sp. and the structure of sulfated xylomannan, Sov. J. Bioorg. Chem., 14, 354
- Miller, 1997, The chemotaxonomic significance of the water-soluble red algal polysaccharides, Recent Res. Dev. Phytochem., 1, 531
Cited by
Sorted by citations
Marine Polysaccharides from Algae with Potential Biomedical Applications
Raposo, M. F. D. J., Morais, A. M. M. B., & Morais, R. M. S. C. (2015) · Marine Drugs · doi:10.3390/md13052967 · Cited by 712
Risks and benefits of consuming edible seaweeds
Cherry, P., O’Hara, C., Magee, P. J., McSorley, E. M., & Allsopp, P. J. (2019) · Nutrition Reviews · doi:10.1093/nutrit/nuy066 · Cited by 440
Carrageenan: Drug Delivery Systems and Other Biomedical Applications
Pacheco-Quito, E.-M., Ruíz, R., & Veiga, M.-D. (2020) · Marine Drugs · doi:10.3390/md18110583 · Cited by 423
Rhein‐Knudsen, N., Ale, M. T., & Meyer, A. S. (2015) · Marine Drugs · doi:10.3390/md13063340 · Cited by 379
Seaweed Potential in the Animal Feed: A Review
Morais, T., Inácio, A. C., Coutinho, T., Ministro, M., Cotas, J., Pereira, L., & Bahćevandžiev, K. (2020) · Journal of Marine Science and Engineering · doi:10.3390/jmse8080559 · Cited by 380
Metadata
- Authors
- Usov, A. I.
- Affiliations
- N.D. Zelinsky Institute of Organic Chemistry (RU)
- Corresponding author
- Usov, Anatolii I.
- Venue
- Advances in carbohydrate chemistry and biochemistry
- Publisher
- Elsevier
- Published
- 2011
- Volume
- 65
- Pages
- 115-217
- ISSN
- 0065-2318 (ISSN-L)
- OpenAlex
- W17843683
- Cited by
- 369
- References
- 703
- Citations by year
- 2026: 24 · 2025: 41 · 2024: 31 · 2023: 36 · 2022: 31 · 2021: 36 · 2020: 35 · 2019: 28 · 2018: 20 · 2017: 21 · 2016: 11 · 2015: 19 · 2014: 13 · 2013: 15 · 2012: 6
- FWCI
- 36.52
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Advances in carbohydrate chemistry and biochemistry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Polysaccharides and Plant Cell Walls
- Keywords
- red algae, sulfated galactans, agar, agarose, carrageenan, xylan, polysaccharide structure, polysaccharide structure elucidation, biologically active polymers, taxonomic markers
- MeSH terms
- Rhodophyta, Carrageenan, Cellulose, Enzymes, Galactans, Hydrolysis, Mannans, Methylation, Magnetic Resonance Spectroscopy, Oxidation-Reduction, Periodic Acid, Polysaccharides, Spectrophotometry, Infrared, Mass Spectrometry, Spectrum Analysis, Raman, Xylans
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review