Methods for determining bioavailability and bioaccessibility of bioactive compounds and nutrients

Plant Polyphenols as Dietary Antioxidants in Human Health and Disease

Pandey, K. B., & Rizvi, S. I. (2009) · Oxidative Medicine and Cellular Longevity · doi:10.4161/oxim.2.5.9498 · Cited by 4,894

Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies

Manach, C., Williamson, G., Morand, C., Scalbert, A., & Rémésy, C. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/81.1.230s · Cited by 4,219

Apple phytochemicals and their health benefits

Boyer, J., & Liu, R. H. (2004) · Nutrition Journal · doi:10.1186/1475-2891-3-5 · Cited by 1,645

Food Microstructure Affects the Bioavailability of Several Nutrients

Parada, J., & Aguilera, J. M. (2007) · Journal of Food Science · doi:10.1111/j.1750-3841.2007.00274.x · Cited by 1,082

In vitro human digestion models for food applications

Hur, S. J., Lim, B. O., Decker, E. A., & McClements, D. J. (2010) · Food Chemistry · doi:10.1016/j.foodchem.2010.08.036 · Cited by 951

Comparison of Five In Vitro Digestion Models To Study the Bioaccessibility of Soil Contaminants

Oomen, A. G., Hack, A., Minekus, M., Zeijdner, E. E., Cornelis, C., Schoeters, G. E. R., Verstraete, W., de Wiele, T. V., Wragg, J., Rompelberg, C. J. M., et al. (2002) · Environmental Science & Technology · doi:10.1021/es010204v · Cited by 812

Applicability of an in vitro digestion model in assessing the bioaccessibility of mycotoxins from food

Versantvoort, C. H. M., Oomen, A. G., de Kamp, E. V., Rompelberg, C. J. M., & Sips, A. J. A. M. (2004) · Food and Chemical Toxicology · doi:10.1016/j.fct.2004.08.007 · Cited by 767

Bioavailability of bioactive food compounds: a challenging journey to bioefficacy.

Rein, M. J., Renouf, M., Cruz-Hernandez, C., Actis-Goretta, L., Thakkar, S. K., & Pinto, M. I. D. S. (2013) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2012.04425.x · Cited by 763

Intake and bioaccessibility of total polyphenols in a whole diet

Saura-Calixto, F. D., Serrano, J. C. E., & Goñi, I. (2006) · Food Chemistry · doi:10.1016/j.foodchem.2006.02.006 · Cited by 740

An in vitro method for estimation of iron availability from meals

Miller, D. D., Schricker, B. R., Rasmussen, R. R., & Campen, D. R. V. (1981) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/34.10.2248 · Cited by 708

The Role of Dietary Fiber in the Bioaccessibility and Bioavailability of Fruit and Vegetable Antioxidants

Palafox-Carlos, H., Ayala-Zavala, J. F., & González-Aguilar, G. A. (2011) · Journal of Food Science · doi:10.1111/j.1750-3841.2010.01957.x · Cited by 686

A Multicompartmental Dynamic Computer-controlled Model Simulating the Stomach and Small Intestine

Minekus, M., Marteau, P., Havenaar, R., & Veld, J. H. J. H. I. (1995) · Alternatives to Laboratory Animals · doi:10.1177/026119299502300205 · Cited by 686

In vitro bio-accessibility and antioxidant activity of grape polyphenols

Tagliazucchi, D., Verzelloni, E., Bertolini, D., & Conte, A. (2009) · Food Chemistry · doi:10.1016/j.foodchem.2009.10.030 · Cited by 683

Fruits and vegetables, as a source of nutritional compounds and phytochemicals: Changes in bioactive compounds during lactic fermentation

Septembre‐Malaterre, A., Remize, F., & Poucheret, P. (2017) · Food Research International · doi:10.1016/j.foodres.2017.09.031 · Cited by 657

Total phenolics, flavonoids, anthocyanins and antioxidant activity following simulated gastro-intestinal digestion and dialysis of apple varieties: Bioaccessibility and potential uptake

Bouayed, J., Hoffmann, L., & Bohn, T. (2011) · Food Chemistry · doi:10.1016/j.foodchem.2011.02.052 · Cited by 656

Disintegration of Solid Foods in Human Stomach

Kong, F., & Singh, R. P. (2008) · Journal of Food Science · doi:10.1111/j.1750-3841.2008.00766.x · Cited by 629

In vitro bioaccessibility assessment as a prediction tool of nutritional efficiency

Fernández‐García, E., Carvajal-Lérida, I., & Pérez‐Gálvez, A. (2009) · Nutrition Research · doi:10.1016/j.nutres.2009.09.016 · Cited by 597

Analytical Methods for Determining Bioavailability and Bioaccessibility of Bioactive Compounds from Fruits and Vegetables: A Review.

Carbonell-Capella, J. M., Buniowska, M., Barba, F., Esteve, M., & Frígola, A. (2014) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12049 · Cited by 580

Relevance and challenges in modeling human gastric and small intestinal digestion

Guerra, A., Etienne‐Mesmin, L., Livrelli, V., Denis, S., Blanquet‐Diot, S., & Alric, M. (2012) · Trends in biotechnology · doi:10.1016/j.tibtech.2012.08.001 · Cited by 569

Bioavailability of dietary flavonoids and phenolic compounds

Crozier, A., Rio, D. D., & Clifford, M. N. (2010) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2010.09.007 · Cited by 568

Stability of polyphenols in chokeberry (Aronia melanocarpa) subjected to in vitro gastric and pancreatic digestion

BERMUDEZSOTO, M., Tomás-Barberán, F. A., & García‐Conesa, M. (2006) · Food Chemistry · doi:10.1016/j.foodchem.2006.06.025 · Cited by 562

Nutrients and phytochemicals: from bioavailability to bioefficacy beyond antioxidants

Holst, B., & Williamson, G. (2008) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2008.03.003 · Cited by 536

C AROTENOID B IOAVAILABILITY AND B IOCONVERSION

Yeum, K., & Russell, R. M. (2002) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.22.010402.102834 · Cited by 535

Development of an in Vitro Digestion Method To Assess Carotenoid Bioavailability from Meals

Garrett, D., Failla, M. L., & Sarama, R. J. (1999) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9903298 · Cited by 505

A computer-controlled system to simulate conditions of the large intestine with peristaltic mixing, water absorption and absorption of fermentation products

Minekus, M., Smeets-Peeters, M. J. E., Bernalier, A., Marol-Bonnin, S., Havenaar, R., Marteau, P. R., Alric, M., Fonty, G., & Veld, J. H. J. H. I. (1999) · Applied Microbiology and Biotechnology · doi:10.1007/s002530051622 · Cited by 459

A Human Gastric Simulator (HGS) to Study Food Digestion in Human Stomach

Kong, F., & Singh, R. P. (2010) · Journal of Food Science · doi:10.1111/j.1750-3841.2010.01856.x · Cited by 428

Application of in vitro bioaccessibility and bioavailability methods for calcium, carotenoids, folate, iron, magnesium, polyphenols, zinc, and vitamins B6, B12, D, and E

Etcheverry, P., Grusak, M. A., & Fleige, L. E. (2012) · Frontiers in Physiology · doi:10.3389/fphys.2012.00317 · Cited by 395

Food processing strategies to enhance phenolic compounds bioaccessibility and bioavailability in plant-based foods

Ribas, A. I., Martín‐Belloso, O., Soliva‐Fortuny, R., & Elez‐Martínez, P. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2017.1331200 · Cited by 374

Organotypic liver culture models: meeting current challenges in toxicity testing

LeCluyse, E. L., Witek, R. P., Andersen, M. E., & Powers, M. J. (2012) · Critical Reviews in Toxicology · doi:10.3109/10408444.2012.682115 · Cited by 363

Modulation of adipose tissue inflammation by bioactive food compounds

Siriwardhana, N., Kalupahana, N. S., Cekanova, M., LeMieux, M. J., Greer, B. P., & Moustaïd‐Moussa, N. (2013) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2012.12.013 · Cited by 360

Advances and perspectives in in vitro human gut fermentation modeling

Payne, A. N., Zihler, A., Chassard, C., & Lacroix, C. (2011) · Trends in biotechnology · doi:10.1016/j.tibtech.2011.06.011 · Cited by 359

Bioaccessibility and antioxidant potential of millet grain phenolics as affected by simulated in vitro digestion and microbial fermentation

Chandrasekara, A., & Shahidi, F. (2012) · Journal of Functional Foods · doi:10.1016/j.jff.2011.11.001 · Cited by 334

Micro- and nano bio-based delivery systems for food applications: In vitro behavior

Simões, L. S., Madalena, D. A., Pinheiro, A. C., Teixeira, J. A., Vicente, A. A., & Ramos, Ó. L. (2017) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2017.02.010 · Cited by 299

Bioaccessibility of bioactive compounds from fruits and vegetables after thermal and nonthermal processing

Barba, F. J., Mariutti, L. R. B., Bragagnolo, N., Mercadante, A. Z., Barbosa‐Cánovas, G. V., & Orlien, V. (2017) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2017.07.006 · Cited by 296

Characterization of Caco-2 and HT29-MTX cocultures in an in vitro digestion/cell culture model used to predict iron bioavailability

Mahler, G. J., Shuler, M. L., & Glahn, R. P. (2008) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2008.05.006 · Cited by 289

Chlorogenic Acid Is Absorbed in Its Intact Form in the Stomach of Rats

Lafay, S., Gil‐Izquierdo, Á., Manach, C., Morand, C., Besson, C., & Scalbert, A. (2006) · Journal of Nutrition · doi:10.1093/jn/136.5.1192 · Cited by 256

A dynamic model that simulates the human upper gastrointestinal tract for the study of probiotics

Mainville, I., Arcand, Y., & Farnworth, E. R. (2004) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2004.08.020 · Cited by 245

Challenges to understanding and measuring carotenoid bioavailability

Faulks, R. M., & Southon, S. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2004.11.012 · Cited by 230

Ferulic Acid Is Quickly Absorbed from Rat Stomach as the Free Form and Then Conjugated Mainly in Liver

Zhao, Z., Egashira, Y., & Sanada, H. (2004) · Journal of Nutrition · doi:10.1093/jn/134.11.3083 · Cited by 216

An in vitro method to simulate phenolic compound release from the food matrix in the gastrointestinal tract

Gil‐Izquierdo, Á., Zafrilla, P., & Tomás-Barberán, F. A. (2002) · European Food Research and Technology · doi:10.1007/s00217-001-0428-3 · Cited by 209

Bioaccessibility assessment methodologies and their consequences for the risk–benefit evaluation of food

Cardoso, C. L., Afonso, C. M., Lourenço, H. M., Costa, S., & Nunes, M. L. (2014) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2014.08.008 · Cited by 200

In vitro bioaccessibility and antioxidant activity of anthocyanins from mulberry (Morus atropurpurea Roxb.) following simulated gastro-intestinal digestion

Liang, L., Wu, X., Zhao, T., Zhao, J., Li, F., Zou, Y., Mao, G., & Yang, L. (2011) · Food Research International · doi:10.1016/j.foodres.2011.11.024 · Cited by 198

In Vitro Bioaccessibility of Carotenoids, Flavonoids, and Vitamin C from Differently Processed Oranges and Orange Juices [Citrus sinensis (L.) Osbeck]

Aschoff, J. K., Kaufmann, S., Kalkan, O., Neidhart, S., Carle, R., & Schweiggert, R. M. (2014) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf505297t · Cited by 198

Assessment of Lutein Bioavailability from Meals and a Supplement Using Simulated Digestion and Caco-2 Human Intestinal Cells

Chitchumroonchokchai, C., Schwartz, S. J., & Failla, M. L. (2004) · Journal of Nutrition · doi:10.1093/jn/134.9.2280 · Cited by 198

Assessment of Degradation and Intestinal Cell Uptake of Carotenoids and Chlorophyll Derivatives from Spinach Puree Using an In Vitro Digestion and Caco-2 Human Cell Model

Ferruzzi, M. G., Failla, M. L., & Schwartz, S. J. (2001) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf000775r · Cited by 189

Effects of a high fat meal matrix and protein complexation on the bioaccessibility of blueberry anthocyanins using the TNO gastrointestinal model (TIM-1)

Ribnicky, D., Roopchand, D. E., Oren, A., Grace, M. H., Poulev, A., Lila, M. A., Havenaar, R., & Raskin, I. (2013) · Food Chemistry · doi:10.1016/j.foodchem.2013.07.073 · Cited by 188

Changes in Vitamin C, Phenolic, and Carotenoid Profiles Throughout in Vitro Gastrointestinal Digestion of a Blended Fruit Juice

Roque, M. J. R., Rojas‐Graü, M. A., Elez‐Martínez, P., & Martín‐Belloso, O. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf3044204 · Cited by 188

A method for the determination of cellular permeability coefficients and aqueous boundary layer thickness in monolayers of intestinal epithelial ( Caco-2) cells grown in permeable filter chambers

Karlsson, J. E., & Artursson, P. (1991) · International Journal of Pharmaceutics · doi:10.1016/0378-5173(91)90067-x · Cited by 187

In-vivo and in-vitro testing to assess the bioaccessibility and the bioavailability of arsenic, selenium and mercury species in food samples

Moreda-Piñeiro, J., Moreda-Piñeiro, A., Romarís-Hortas, V., Moscoso-Pérez, C., López-Mahía, P., Muniategui-Lorenzo, S., Bermejo-Barrera, P., & Prada-Rodríguez, D. (2011) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2010.09.008 · Cited by 182

Bound Ferulic Acid from Bran Is More Bioavailable than the Free Compound in Rat

Rondini, L., Maillard, M., Marsset‐Baglieri, A., Fromentin, G., Durand, P., Tomé, D., Prost, M., & Berset, C. (2004) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0348323 · Cited by 178

In vitro digestion and lactase treatment influence uptake of quercetin and quercetin glucoside by the Caco-2 cell monolayer

Boyer, J., Brown, D. L., & Liu, R. H. (2005) · Nutrition Journal · doi:10.1186/1475-2891-4-1 · Cited by 176

Bioaccessibility of carotenes from carrots: Effect of cooking and addition of oil

Hornero‐Méndez, D., & Mínguez‐Mosquera, M. I. (2007) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2007.03.014 · Cited by 172

Application of in vitro gastrointestinal digestion and colonic fermentation models to pomegranate products (juice, pulp and peel extract) to study the stability and catabolism of phenolic compounds

Mosele, J. I., Macià, A., Romero, M.-P., Motilva, M., & Rubió, L. (2015) · Journal of Functional Foods · doi:10.1016/j.jff.2015.02.026 · Cited by 168

Stability and metabolism of Arbutus unedo bioactive compounds (phenolics and antioxidants) under in vitro digestion and colonic fermentation

Mosele, J. I., Macià, A., Romero, M.-P., & Motilva, M.-J. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2016.01.076 · Cited by 168

In vitro digestion and fermentation methods, including gas production techniques, as applied to nutritive evaluation of foods in the hindgut of humans and other simple-stomached animals

Coles, L., Moughan, P., & Darragh, A. (2005) · Animal Feed Science and Technology · doi:10.1016/j.anifeedsci.2005.04.021 · Cited by 162

Achieving Antral Grinding Forces in Biorelevant In Vitro Models: Comparing the USP Dissolution Apparatus II and the Dynamic Gastric Model with Human In Vivo Data

Vardakou, M., Mercuri, A., Barker, S. A., Craig, D. Q. M., Faulks, R. M., & Wickham, M. S. J. (2011) · AAPS PharmSciTech · doi:10.1208/s12249-011-9616-z · Cited by 162

Bioaccessibility of minerals in school meals: Comparison between dialysis and solubility methods

Cámara‐Martos, F., Amaro, M., Barberá, R., & Clemente, G. (2004) · Food Chemistry · doi:10.1016/j.foodchem.2004.08.009 · Cited by 160

Bioavailability of Phenolic Antioxidants Associated with Dietary Fiber: Plasma Antioxidant Capacity After Acute and Long-Term Intake in Humans

Pérez‐Jiménez, J., Serrano, J. C. E., Tabernero, M., Arranz, S., Diaz-Rubio, M. E., García‐Diz, L., Goñi, I., & Saura-Calixto, F. D. (2009) · Plant Foods for Human Nutrition · doi:10.1007/s11130-009-0110-7 · Cited by 159

Changes in β-carotene bioaccessibility and concentration during processing of carrot puree

Knockaert, G., Lemmens, L., Buggenhout, S. V., Hendrickx, M., & Loey, A. M. V. (2012) · Food Chemistry · doi:10.1016/j.foodchem.2011.12.066 · Cited by 154

High pressure homogenization processing, thermal treatment and milk matrix affect in vitro bioaccessibility of phenolics in apple, grape and orange juice to different extents

He, Z., Tao, Y., Zeng, M., Zhang, S., Tao, G., Qin, F., & Chen, J. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2016.01.045 · Cited by 151

Novel and established intestinal cell line models – An indispensable tool in food science and nutrition

Langerholc, T., Maragkoudakis, P. A., Wollgast, J., Gradišnik, L., & Čenčič, A. (2011) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2011.03.010 · Cited by 150

Phenolic Acids Are Absorbed from the Rat Stomach with Different Absorption Rates

Konishi, Y., Zhao, Z., & Shimizu, M. (2006) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf061554+ · Cited by 143

Consumer product in vitro digestion model: Bioaccessibility of contaminants and its application in risk assessment

Brandon, E. F. A., Oomen, A. G., Rompelberg, C. J. M., Versantvoort, C. H. M., van Engelen, J. G. M., & Sips, A. J. A. M. (2005) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2005.10.002 · Cited by 136

Effect of Orange Juice’s Processing on the Color, Particle Size, and Bioaccessibility of Carotenoids

Stinco, C. M., Fernández‐Vázquez, R., Escudero-Gilete, M. L., Heredia, F. J., Meléndez‐Martínez, A. J., & Vicario, I. M. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf2043949 · Cited by 134

Bioaccessibility of Tocopherols, Carotenoids, and Ascorbic Acid from Milk- and Soy-Based Fruit Beverages: Influence of Food Matrix and Processing

Cilla, A., Alegrı́a, A., de Ancos, B., Sánchez‐Moreno, C., Cano, M. P., Plaza, L., Clemente, G., Lagarda, M. J., & Barberá, R. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf301165r · Cited by 133

Effect of in vitro gastrointestinal digestion on the bioavailability of phenolic components and the antioxidant potentials of some Turkish fruit wines

Celep, E., Charehsaz, M., Akyüz, S., Acar, E. T., & Yeşilada, E. (2015) · Food Research International · doi:10.1016/j.foodres.2015.10.009 · Cited by 132

A level A in vitro/in vivo correlation in fasted and fed states using different methods: Applied to solid immediate release oral dosage form

Souliman, S., Blanquet, S., Beyssac, E., & Cardot, J. (2005) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2005.08.006 · Cited by 128

Decreased colonization of fecal Clostridium coccoides/Eubacterium rectale species from ulcerative colitis patients in an in vitro dynamic gut model with mucin environment

Vermeiren, J., den Abbeele, P. V., Laukens, D., Vigsnæs, L. K., Vos, M. D., Boon, N., & de Wiele, T. V. (2011) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2011.01252.x · Cited by 126

The influences of drying method and metabisulfite pre-treatment on the color, functional properties and phenolic acids contents and bioaccessibility of pumpkin flour

Aydın, E., & Göçmen, D. (2014) · LWT · doi:10.1016/j.lwt.2014.08.025 · Cited by 125

Bioaccessibility of essential elements from white cheese, bread, fruit and vegetables

Khouzam, R. B., Pohl, P., & Łobiński, R. (2011) · Talanta · doi:10.1016/j.talanta.2011.08.049 · Cited by 123

Enhanced oral bioavailability and in vivo antioxidant activity of chlorogenic acid via liposomal formulation

Feng, Y., Sun, C., Yuan, Y., Zhu, Y., Wan, J., Firempong, C. K., Omari‐Siaw, E., Xu, Y., Pu, Z., Yu, J., et al. (2016) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2016.01.081 · Cited by 119

Flavanols: digestion, absorption and bioactivity

Hackman, R. M., Polagruto, J. A., Zhu, Q. Y., Sun, B., Fujii, H., & Keen, C. L. (2007) · Phytochemistry Reviews · doi:10.1007/s11101-007-9070-4 · Cited by 118

Changes in the antioxidant activities of vegetables as a consequence of interactions between active compounds

Gawlik‐Dziki, U. (2012) · Journal of Functional Foods · doi:10.1016/j.jff.2012.06.004 · Cited by 117

Estimation of carotenoid bioavailability from fresh stir-fried vegetables using an in vitro digestion/Caco-2 cell culture model

Garrett, D., Failla, M. L., & Sarama, R. J. (2000) · The Journal of Nutritional Biochemistry · doi:10.1016/s0955-2863(00)00122-4 · Cited by 114

Bioaccessibility of polyphenols and cinnamaldehyde in cinnamon beverages subjected to in vitro gastro-pancreatic digestion

Helal, A., Tagliazucchi, D., Verzelloni, E., & Conte, A. (2014) · Journal of Functional Foods · doi:10.1016/j.jff.2014.01.005 · Cited by 113

An Investigation into the Utility of a Multi-compartmental, Dynamic, System of the Upper Gastrointestinal Tract to Support Formulation Development and Establish Bioequivalence of Poorly Soluble Drugs

Dickinson, P. A., Abu-Rmaileh, R., Ashworth, L., Barker, R. A., Burke, W., Patterson, C. M., Stainforth, N. M., & Yasin, M. (2012) · The AAPS Journal · doi:10.1208/s12248-012-9333-x · Cited by 111

In vitro fermentation of juçara pulp ( Euterpe edulis ) by human colonic microbiota

Guergoletto, K. B., Costabile, A., Flores, G., García, S., & Gibson, G. R. (2015) · Food Chemistry · doi:10.1016/j.foodchem.2015.09.048 · Cited by 109

Chlorogenic acid is poorly absorbed, independently of the food matrix: A Caco‐2 cells and rat chronic absorption study

Dupas, C., Marsset‐Baglieri, A., Ordonaud, C. S., Tomé, D., & Maillard, M. (2006) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200600034 · Cited by 105

Bioaccessibility of bioactive compounds and antioxidant potential of juçara fruits (Euterpe edulis Martius) subjected to in vitro gastrointestinal digestion

Schulz, M., Biluca, F. C., Gonzaga, L. V., Borges, G. D. S. C., Vitali, L., Micke, G. A., de Gois, J. S., Almeida, T. S., Borges, D. L. G., Miller, P. R., et al. (2017) · Food Chemistry · doi:10.1016/j.foodchem.2017.02.038 · Cited by 105

Carotenoid and polyphenol bioaccessibility and cellular uptake from plum and cabbage varieties

Kaulmann, A., André, C. M., Schneider, Y., Hoffmann, L., & Bohn, T. (2015) · Food Chemistry · doi:10.1016/j.foodchem.2015.10.049 · Cited by 103

Effect of Stevia rebaudiana addition on bioaccessibility of bioactive compounds and antioxidant activity of beverages based on exotic fruits mixed with oat following simulated human digestion

Carbonell‐Capella, J. M., Buniowska, M., Esteve, M. J., & Frígola, A. (2015) · Food Chemistry · doi:10.1016/j.foodchem.2015.03.095 · Cited by 102

Nutritional composition and bioactive properties of commonly consumed wild greens: Potential sources for new trends in modern diets

Pereira, C., Barros, L., Carvalho, A. M., & Ferreira, I. C. F. R. (2011) · Food Research International · doi:10.1016/j.foodres.2011.05.012 · Cited by 100

Ultrasound processing to enhance drying of cashew apple bagasse puree: Influence on antioxidant properties and in vitro bioaccessibility of bioactive compounds

Fonteles, T. V., Leite, A. K. F., Silva, A. R. A., Carneiro, A. P. D. G., Miguel, E. D. C., Cavada, B. S., Fernandes, F. A. N., & Rodrigues, S. (2016) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2016.01.003 · Cited by 99

Effects of freezing, freeze drying and convective drying on in vitro gastric digestion of apples

Dalmau, E., Bornhorst, G. M., Eim, V. S., Rosselló, C., & Simal, S. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2016.07.134 · Cited by 98

Nutraceutical potential and antioxidant benefits of selected fruit seeds subjected to an in vitro digestion

Chen, G., Chen, S.-G., Chen, F., Xie, Y.-Q., Han, M.-D., Luo, C., Zhao, Y., & Gao, Y. (2015) · Journal of Functional Foods · doi:10.1016/j.jff.2015.11.003 · Cited by 97

Acrylamide in Food: Analysis, Content and Potential Health Effects

Gökmen, V. (2015) · Cited by 96

Bioaccessibility of (poly)phenolic compounds of raw and cooked cardoon (Cynara cardunculus L.) after simulated gastrointestinal digestion and fermentation by human colonic microbiota

Juániz, I., Ludwig, I. A., Bresciani, L., Dall’Asta, M., Mena, P. R., Rio, D. D., Cid, C., & Peña, M.-P. D. (2017) · Journal of Functional Foods · doi:10.1016/j.jff.2017.02.033 · Cited by 95

Antioxidant and antiproliferative activity of chokeberry juice phenolics during in vitro simulated digestion in the presence of food matrix

Stanisavljević, N. S., Samardžić, J. T., Janković, T., Šavikin, K., Mojsin, M. M., Topalović, V., & Stevanović, M. J. (2014) · Food Chemistry · doi:10.1016/j.foodchem.2014.12.009 · Cited by 95

Bioaccessibility of bioactive compounds after non-thermal processing of an exotic fruit juice blend sweetened with Stevia rebaudiana

Buniowska, M., Carbonell‐Capella, J. M., Frígola, A., & Esteve, M. J. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2016.10.093 · Cited by 94

Influence of Chocolate Matrix Composition on Cocoa Flavan-3-ol Bioaccessibility In Vitro and Bioavailability in Humans

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Optimisation of in vitro measurement of available iron from different fortificants in citric fruit juices

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Development of anin vitrosystem simulating bucco-gastric digestion to assess the physical and chemical changes of food

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In vitrolipid digestion models in design of drug delivery systems for enhancing oral bioavailability

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In vitro modulation of the human gastrointestinal microbial community by plant-derived polysaccharide-rich dietary supplements

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Development of a simple model device for in vitro gastric digestion investigation

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Identification of bioaccessible and uptaken phenolic compounds from strawberry fruits in in vitro digestion/Caco-2 absorption model

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The Effect of Composition and Gastric Conditions on the Self-Emulsification Process of Ibuprofen-Loaded Self-Emulsifying Drug Delivery Systems: A Microscopic and Dynamic Gastric Model Study

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Investigation into the bioaccessibility and microstructure changes of β-carotene emulsions during in vitro digestion

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Processing of three different cooking methods of cassava: Effects on in vitro bioaccessibility of phenolic compounds and antioxidant activity

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In vitro bioaccessibility of health-related compounds from a blended fruit juice–soymilk beverage: Influence of the food matrix

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Use of Artificial Digestive Systems to Investigate the Biopharmaceutical Factors Influencing the Survival of Probiotic Yeast During Gastrointestinal Transit in Humans

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The fortification of tea with sweeteners and milk and its effect on in vitro antioxidant potential of tea product and glutathione levels in an animal model

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Comparison of a static and a dynamic in vitro model to estimate the bioaccessibility of As, Cd, Pb and Hg from food reference materials Fucus sp. (IAEA-140/TM) and Lobster hepatopancreas (TORT-2)

Torres-Escribano, S., Denis, S., Blanquet‐Diot, S., Calatayud, M., Barrios, L., Vélez, D., Alric, M., & Montoro, R. (2010) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2010.10.021 · Cited by 69

Antioxidant capacity of Brazilian fruit, vegetables and commercially-frozen fruit pulps

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Changes in iron, zinc and chelating agents during traditional African processing of maize: Effect of iron contamination on bioaccessibility

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Change in stability of procyanidins, antioxidant capacity and in-vitro bioaccessibility during processing of cocoa powder from cocoa beans

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Integrating the issues of folate bioavailability, intake and metabolism in the era of fortification

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Does flavor impact function? Potential consequences of polyphenol–protein interactions in delivery and bioactivity of flavan-3-ols from foods

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A simple method for the speciation analysis of bio-accessible arsenic in seafood using on-line continuous leaching and ion exchange chromatography coupled to inductively coupled plasma mass spectrometry

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Simple method to assess the maximum bio-accessibility of elements from food using flow injection and inductively coupled plasma mass spectrometry

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Potentially bioaccessible phenolics, antioxidant activity and nutritional quality of young buckwheat sprouts affected by elicitation and elicitation supported by phenylpropanoid pathway precursor feeding

Świeca, M. (2015) · Food Chemistry · doi:10.1016/j.foodchem.2015.07.058 · Cited by 46

In vitro procedure to predict apparent antioxidant release from wholegrain foods measured using three different analytical methods

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THE FIRST TRACT OF ALIMENTARY CANAL AS AN EXTRACTOR. RELEASE OF PHYTOCHEMICALS FROM SOLID FOOD MATRICES DURING SIMULATED DIGESTION

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Enhancing the in vitro Fe2+ bio-accessibility using ascorbate and cold-set whey protein gel particles

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In vitro estimates of bioaccessible nickel in field-contaminated soils, and comparison with in vivo measurement of bioavailability and identification of mineralogy

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Lutein-enriched frankfurter-type products: Physicochemical characteristics and lutein in vitro bioaccessibility

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Content and bioaccessibility of carotenoids from organic and non-organic baby foods

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Bioaccessibility of individual phenolic compounds in extra virgin argan oil after simulated gastrointestinal process

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Ferritin synthesis by Caco-2 cells as an indicator of iron bioavailability: Application to milk-based infant formulas

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The effect of folate-binding proteins on bioavailability of folate from milk products

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Sustainable processing of food waste for production of bio-based products for circular bioeconomy

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Functional importance of bioactive compounds of foods with Potential Health Benefits: A review on recent trends

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Encapsulation of Active Ingredients in Food Industry by Spray-Drying and Nano Spray-Drying Technologies

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Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Medicinal Fungus Cordyceps with Its Nutraceutical and Therapeutic Potential

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Seaweed Components as Potential Modulators of the Gut Microbiota

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Current state and future perspectives of supercritical fluid chromatography

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Sufficiency, E., Qamar, S. A., Ferreira, L. F. R., Franco, M., Iqbal, H. M. N., & Bilal, M. (2022) · Energy Nexus · doi:10.1016/j.nexus.2022.100077 · Cited by 50

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