Triggers for cocaine and alcohol use in the presence and absence of posttraumatic stress disorder
Abstract
The present study compared high-risk triggers and substance use situations among 72 (34 men, 38 women) individuals with alcohol (AD) or cocaine dependence (CD), with or without comorbid PTSD. Consistent with the self-medication hypothesis, individuals with PTSD reported significantly greater use of substances in response to negative situations, such as unpleasant emotions and physical discomfort, as compared to individuals without PTSD. CD individuals were significantly more likely than AD individuals to report using in temptation situations, regardless of PTSD status. Also, CD individuals with PTSD reported greater use of cocaine during pleasant times with others, as compared to those without PTSD. The findings highlight the importance of addressing individual-specific high-risk situations in relapse prevention.
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The finding of less substance use is in line with a previous local study of coping responses of emergency room staff but contrary to previous studies that noted increased substance use in individuals facing stress.
“The less use of substance in our study is in line with a previous local study of coping responses of staff within an emergency room setting [32] but is contrary to the findings of some previous studies [44], [45], which had noted increased substance use in individuals facing stress.”
From Psychosocial and coping responses within the community health care setting towards a national outbreak of an infectious disease (2010) · cites this paper as [45]
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Transtorno de estresse pós-traumático em dependente do álcool
Pulcherio, G., Vernetti, C. L., Strey, M. N., & Faller, S. (2008) · Archives of Clinical Psychiatry (São Paulo) · doi:10.1590/s0101-60832008000400005 · Cited by 8 · see citing works
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Amstadter, A. B., Lönn, S. L., Sundquist, J., Kendler, K. S., & Sundquist, K. (2022) · Journal of Studies on Alcohol and Drugs · doi:10.15288/jsad.22-00209 · Cited by 7 · see citing works
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Panayiotou, G., Artemi, T.-F., Theodorou, M., Theodorou, C., & Neophytou, K. (2023) · Cogent Psychology · doi:10.1080/23311908.2023.2183677 · Cited by 7 · see citing works
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The moderating role of dysphoria in the relationship between intrusions and alcohol use
Contractor, A. A., Presseau, C., Capone, C., Reddy, M. K., & Shea, M. T. (2015) · Addictive Behaviors · doi:10.1016/j.addbeh.2015.12.010 · Cited by 7 · see citing works
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- Authors
- Waldrop, A. E., Back, S. E., Verduin, M. L., & Brady, K. T.
- Affiliations
- Medical University of South Carolina (US)
- Corresponding author
- Waldrop, Angela E.
- Venue
- Addictive Behaviors
- Publisher
- Elsevier BV
- Published
- 2007-03
- Volume
- 32
- Issue
- 3
- Pages
- 634-639
- ISSN
- 0306-4603 (ISSN-L)
- OpenAlex
- W2011693745
- Cited by
- 147
- References
- 13
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 2 · 2023: 8 · 2022: 4 · 2021: 13 · 2020: 10 · 2019: 11 · 2018: 7 · 2017: 3 · 2016: 9 · 2015: 15 · 2014: 8 · 2013: 13 · 2012: 10
- FWCI
- 3.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Addictive Behaviors (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- U.S. Public Health Service (M01 RRO 1070)
- National Institute on Alcohol Abuse and Alcoholism (P50 AA 10751)
- National Institute on Drug Abuse (F31DA006077, K24DA000435)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (P50 AR 049551)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Keywords
- cocaine dependence, alcoholism, post-traumatic stress disorder, self-medication hypothesis, relapse prevention, emotional distress, comorbidities
- MeSH terms
- Adult, Alcohol Drinking, Emotions, Female, Humans, Male, Pain, Recurrence, Self Medication, Stress Disorders, Post-Traumatic, Cocaine-Related Disorders
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