Targeted delivery of nanoparticles for the treatment of lung diseases

Continuous cultures of fused cells secreting antibody of predefined specificity

Köhler, G., & Milstein, C. (1975) · Nature · doi:10.1038/256495a0 · Cited by 17,200

Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy

Oberdörster, G., Maynard, A., Donaldson, K., Castranova, V., Fitzpatrick, J., Ausman, K., Carter, J., Karn, B., Kreyling, W., Lai, D., et al. (2005) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-2-8 · Cited by 2,134

Drug Delivery and Targeting

Hillery, A. M., Lloyd, A. W., & Swarbrick, J. (2016) · CRC Press eBooks · doi:10.1201/b12801 · Cited by 2,031

Comparison of the Abilities of Ambient and Manufactured Nanoparticles To Induce Cellular Toxicity According to an Oxidative Stress Paradigm

Xia, T., Kovochich, M., Brant, J. A., Hotze, M., Sempf, J. M., Oberley, T. D., Sioutas, C., Yeh, J. I., Wiesner, M. R., & Nel, A. E. (2006) · Nano Letters · doi:10.1021/nl061025k · Cited by 1,931

Comparative Pulmonary Toxicity Assessment of Single-wall Carbon Nanotubes in Rats

Warheit, D. B. (2003) · Toxicological Sciences · doi:10.1093/toxsci/kfg228 · Cited by 1,531

Large Porous Particles for Pulmonary Drug Delivery

Edwards, D. A., Hanes, J. S., Caponetti, G., Hrkach, J. S., Ben-Jebria, A., Eskew, M. L., Mintzes, J. D., Deaver, D. R., Lotan, N., & Langer, R. (1997) · Science · doi:10.1126/science.276.5320.1868 · Cited by 1,184

Nanoparticle Uptake by the Rat Gastrointestinal Mucosa: Quantitation and Particle Size Dependency

Jani, P., Halbert, G. W., Langridge, J., & Florence, A. T. (1990) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1990.tb07033.x · Cited by 920

Assessing Toxicity of Fine and Nanoparticles: Comparing In Vitro Measurements to In Vivo Pulmonary Toxicity Profiles

Sayes, C. M., Reed, K. L., & Warheit, D. B. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfm018 · Cited by 769

The Potential Advantages of Nanoparticle Drug Delivery Systems in Chemotherapy of Tuberculosis

Gelperina, S. E., Kisich, K. O., Iseman, M. D., & Heifets, L. B. (2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200504-613pp · Cited by 744

Abraxane®, a novel Cremophor®-free, albumin-bound particle form of paclitaxel for the treatment of advanced non-small-cell lung cancer

Green, M. R., Manikhas, G. M., Орлов, С. В., Afanasyev, B. V., Makhson, A. M., Bhar, P., & Hawkins, M. (2006) · Annals of Oncology · doi:10.1093/annonc/mdl104 · Cited by 671

Trojan particles: Large porous carriers of nanoparticles for drug delivery

Tsapis, N., Bennett, D., Jackson, B., Weitz, D. A., & Edwards, D. A. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.182233999 · Cited by 546

Toxicity of Cerium Oxide Nanoparticles in Human Lung Cancer Cells

Lin, W., Huang, Y., Zhou, X., & Ma, Y. (2006) · International Journal of Toxicology · doi:10.1080/10915810600959543 · Cited by 537

Significant Transport of Doxorubicin into the Brain with Polysorbate 80-Coated Nanoparticles

Gulyaev, A. E., Gelperina, S. E., Skidan, I. N., Antropov, A. S., Kivman, G. Y., & Kreuter, J. (1999) · Pharmaceutical Research · doi:10.1023/a:1018983904537 · Cited by 521

Chronic inhalation exposure of wistar rats and two different strains of mice to diesel engine exhaust, carbon black, and titanium dioxide

Heinrich, U., Fuhst, R., Rittinghausen, S., Creutzenberg, O., Bellmann, B., Koch, W., & Levsen, K. (1995) · Inhalation Toxicology · doi:10.3109/08958379509015211 · Cited by 514

Microencapsulated chitosan nanoparticles for lung protein delivery

Grenha, A., Seijo, B., & Remuñán‐López, C. (2005) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2005.04.009 · Cited by 469

Ultrafine Particle Deposition and Clearance in the Healthy and Obstructed Lung

Brown, J. S., Zeman, K. L., & Bennett, W. D. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200205-399oc · Cited by 444

The Uptake and Translocation of Latex Nanospheres and Microspheres after Oral Administration to Rats

Jani, P. U., Halbert, G., Langridge, J., & Florence, A. T. (1989) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1989.tb06377.x · Cited by 394

Surface-modified PLGA nanosphere with chitosan improved pulmonary delivery of calcitonin by mucoadhesion and opening of the intercellular tight junctions

Yamamoto, H., Kuno, Y., Sugimoto, S., Takeuchi, H., & Kawashimà, Y. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.10.010 · Cited by 389

Poly (DL-lactide-co-glycolide) nanoparticle-based inhalable sustained drug delivery system for experimental tuberculosis

Pandey, R. (2003) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkg477 · Cited by 389

Impairment of Alveolar Macrophage Phagocytosis by Ultrafine Particles

Renwick, L., Donaldson, K., & Clouter, A. (2001) · Toxicology and Applied Pharmacology · doi:10.1006/taap.2001.9128 · Cited by 320

Pulmonary Drug Delivery Systems: Recent Developments and Prospects;

Courrier, H. M., Butz, N., & Vandamme, T. F. (2002) · Critical Reviews in Therapeutic Drug Carrier Systems · doi:10.1615/critrevtherdrugcarriersyst.v19.i45.40 · Cited by 318

Solid lipid particle-based inhalable sustained drug delivery system against experimental tuberculosis

Pandey, R., & Khuller, G. K. (2005) · Tuberculosis · doi:10.1016/j.tube.2004.11.003 · Cited by 318

Human respiratory epithelial cell culture for drug delivery applications

Forbes, B., & Ehrhardt, C. (2005) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2005.02.010 · Cited by 307

A novel endocytic pathway induced by clustering endothelial ICAM-1 or PECAM-1

Muro, S., Wiewrodt, R. G., Thomas, A., Koniaris, L. S., Albelda, S. Μ., Muzykantov, V. R., & Koval, M. H. (2003) · Journal of Cell Science · doi:10.1242/jcs.00367 · Cited by 302

Influence of formulation excipients and physical characteristics of inhalation dry powders on their aerosolization performance

Bosquillon, C., Lombry, C., Véronique Préat, A., & Rita Vanbever, A. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(00)00362-x · Cited by 296

Comparative Pulmonary Toxicities and Carcinogenicities of Chronically Inhaled Diesel Exhaust and Carbon Black in F344 Rats

Nikula, K. J. (1995) · Fundamental and Applied Toxicology · doi:10.1006/faat.1995.1042 · Cited by 295

Formulation and characterization of spray-dried powders containing nanoparticles for aerosol delivery to the lung

Sham, J. O.-H., Zhang, Y., Finlay, W. H., Roa, W., & Löbenberg, R. (2003) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2003.09.041 · Cited by 284

Targeted Delivery of Antisense Oligodeoxynucleotide and Small Interference RNA into Lung Cancer Cells

Li, S., & Huang, L. (2006) · Molecular Pharmaceutics · doi:10.1021/mp060039w · Cited by 282

Oral solid lipid nanoparticle-based antitubercular chemotherapy

Pandey, R., Sharma, S., & Khuller, G. K. (2005) · Tuberculosis · doi:10.1016/j.tube.2005.08.009 · Cited by 271

Targeted drug conjugates: principles and progress

Garnett, M. C. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00227-7 · Cited by 262

(D) Routes of delivery: Case studies

Patton, J. S., & Platz, R. M. (1992) · Advanced Drug Delivery Reviews · doi:10.1016/0169-409x(92)90002-8 · Cited by 249

Pulmonary Inflammatory, Chemokine, and Mutagenic Responses in Rats after Subchronic Inhalation of Carbon Black

Driscoll, K. E., Carter, J. M., Howard, B. W., Hassenbein, D. G., Pepelko, W. E., Baggs, R. B., & Oberdörster, G. (1996) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1996.0045 · Cited by 225

Investigation of the proinflammatory potential of biodegradable nanoparticle drug delivery systems in the lung

Dailey, L. A., Jekel, N., Fink, L., Gessler, T., Schmehl, T., Wittmar, M., Kissel, T., & Seeger, W. (2006) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2006.01.016 · Cited by 220

Lymphatic Uptake of Pulmonary Delivered Radiolabelled Solid Lipid Nanoparticles

Videira, M. A., Botelho, M. F., Santos, A. C., Gouveia, L. F., Pedroso de Lima, J. J., & Almeida, A. J. (2002) · Journal of Drug Targeting · doi:10.1080/1061186021000054933 · Cited by 213

Drug-conjugated monoclonal antibodies for the treatment of cancer

Lambert, J. S. (2005) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2005.04.017 · Cited by 210

Tumor-Targeted Gene Delivery Using Poly(Ethylene Glycol)-Modified Gelatin Nanoparticles: In Vitro and in Vivo Studies

Kaul, G., & Amiji, M. M. (2005) · Pharmaceutical Research · doi:10.1007/s11095-005-4590-3 · Cited by 204

Targeted nanoparticles for detecting and treating cancer

Sunderland, C. J., Steiert, M., Talmadge, J. E., Derfus, A. M., & Barry, S. E. (2006) · Drug Development Research · doi:10.1002/ddr.20069 · Cited by 200

Body distribution of fully biodegradable [14C]-poly(lactic acid) nanoparticles coated with albumin after parenteral administration to rats

Bazile, D. V., Ropert, C., Huve, P., Verrecchia, T., Mariard, M., Frydman, A., Veillard, M., & Spenlehauer, G. (1992) · Biomaterials · doi:10.1016/0142-9612(92)90142-b · Cited by 200

Pulmonary delivery of insulin with nebulized dl-lactide/glycolide copolymer (PLGA) nanospheres to prolong hypoglycemic effect

Kawashima, Y., Yamamoto, H., 洋文, 竹., Fujioka, S., & 知証, 日. (1999) · Journal of Controlled Release · doi:10.1016/s0168-3659(99)00048-6 · Cited by 186

Distribution Pattern of Inhaled Ultrafine Gold Particles in the Rat Lung

Takenaka, S., Karg, E. W., Kreyling, W. G., Lentner, B., Möller, W., Behnke-Semmler, M., Jennen, L., Walch, A. K., Michalke, B., Schramel, P., et al. (2006) · Inhalation Toxicology · doi:10.1080/08958370600748281 · Cited by 182

Inhalation of High Concentrations of Low Toxicity Dusts in Rats Results in Impaired Pulmonary Clearance Mechanisms and Persistent Inflammation

Warheit, D. B., Hansen, J. F., Yuen, I. S., Kelly, D. P., Snajdr, S. I., & Hartsky, M. A. (1997) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1997.8102 · Cited by 165

Delivery of Biotherapeutics by Inhalation Aerosol

Niven, R. W. (1995) · Critical Reviews in Therapeutic Drug Carrier Systems · doi:10.1615/critrevtherdrugcarriersyst.v12.i2-3.20 · Cited by 164

Nanoparticle-Based Diagnosis and Therapy

Groneberg, D. A., Giersig, M., Welte, T., & Pison, U. (2006) · Current Drug Targets · doi:10.2174/138945006777435245 · Cited by 158

Pulmonary Delivery of Insulin with Nebulized DL-Lactide/Glycolide Copolymer(PLGA) Nanospheres to Prolong Hypoglycemic Effect.

Kawashima, Yoshiaki, Yamamoto, Y., Hiromitsu, Takéuchi, Hirofumi, Fujioka, Satoshi, S., Hino, & Tomoaki (2000) · 岐阜藥科大學紀要 = The annual proceedings of Gifu College of Pharmacy · Cited by 155

Plasmid size up to 20 kbp does not limit effective in vivo lung gene transfer using compacted DNA nanoparticles

Fink, T. L., Klepcyk, P. J., Oette, S. M., Gedeon, C. R., Hyatt, S. L., Kowalczyk, T. H., Moen, R. C., & Cooper, M. J. (2006) · Gene Therapy · doi:10.1038/sj.gt.3302761 · Cited by 139

Effects of Airway Exposure to Nanoparticles on Lung Inflammation Induced by Bacterial Endotoxin in Mice

Inoue, K., Takano, H., Yanagisawa, R., Hirano, S., Sakurai, M., Shimada, A., & Yoshikawa, T. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.8903 · Cited by 139

Fluorescent Nanoparticle Probes for Cancer Imaging

Santra, S., Dutta, D., Walter, G. A., & Moudgil, B. M. (2005) · Technology in Cancer Research & Treatment · doi:10.1177/153303460500400603 · Cited by 134

Monoclonal antibody drug immunoconjugates for targeted treatment of cancer

Trail, P. A., King, D. H., & Dubowchik, G. M. (2003) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-002-0352-9 · Cited by 129

Ultrafine Particles Cause Cytoskeletal Dysfunctions in Macrophages

Möller, W. (2002) · Toxicology and Applied Pharmacology · doi:10.1006/taap.2002.9430 · Cited by 126

Carbon black nanoparticles induce type II epithelial cells to release chemotaxins for alveolar macrophages

Barlow, P. G., Clouter, A., Donaldson, K., MacCallum, J., & Stone, V. (2005) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-2-11 · Cited by 124

Incorporation of biodegradable nanoparticles into human airway epithelium cells—in vitro study of the suitability as a vehicle for drug or gene delivery in pulmonary diseases

Brzoska, M., Langer, K., Coester, C., Loitsch, S. M., Wagner, T. O. F., & von Mallinckrodt, C. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.04.067 · Cited by 122

PHARMACOKINETICS OF DOXORUBICIN INCORPORATED IN SOLID LIPID NANOSPHERES (SLN)

Zara, G. P., Cavalli, R., Fundaro', A., Bargoni, A., Caputo, O., & Gasco, M. R. (1999) · Pharmacological Research · doi:10.1006/phrs.1999.0509 · Cited by 122

No Significant Translocation of Inhaled 35-nm Carbon Particles to the Circulation in Humans

Wiebert, P., Sánchez-Crespo, A., Falk, R., Philipson, K., Lundin, A., Larsson, S., Möller, W., Kreyling, W. G., & Svartengren, M. (2006) · Inhalation Toxicology · doi:10.1080/08958370600748455 · Cited by 122

Influence of the Surfactant Concentration on the Body Distribution of Nanoparticles

Araújo, L. C. D. P., Löbenberg, R., & Kreuter, J. (1999) · Journal of drug targeting · doi:10.3109/10611869908996844 · Cited by 119

Nanoparticles: Characteristics, Mechanisms of Action, and Toxicity in Pulmonary Drug Delivery—A Review

Gill, S., Löbenberg, R., Ku, T., Azarmi, S., Roa, W., & Prenner, E. J. (2007) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2007.015 · Cited by 118

Body distribution of azidothymidine bound to hexyl-cyanoacrylate nanoparticles after i.v. injection to rats

Löbenberg, R. (1998) · Journal of Controlled Release · doi:10.1016/s0168-3659(97)00105-3 · Cited by 109

Distribution and Elimination of Poly(methyl-2-14C-methacrylate) Nanoparticle Radioactivity after Injection in Rats and Mice

Kreuter, J., Täuber, U., & Illi, V. (1979) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600681129 · Cited by 109

Size-dependent intracellular immunotargeting of therapeutic cargoes into endothelial cells

Wiewrodt, R. G., Thomas, A., Cipelletti, L., Christofidou‐Solomidou, M., Weitz, D. A., Feinstein, S. I., Schaffer, D., Albelda, S. Μ., Koval, M. H., & Muzykantov, V. R. (2002) · Blood · doi:10.1182/blood.v99.3.912 · Cited by 104

Targeting of Antioxidant and Anti-Thrombotic Drugs to Endothelial Cell Adhesion Molecules

Muro, S., & Muzykantov, V. R. (2005) · Current Pharmaceutical Design · doi:10.2174/1381612054367274 · Cited by 101

Subcutaneous nanoparticle-based antitubercular chemotherapy in an experimental model

Pandey, R. B. (2004) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkh260 · Cited by 91

Formulating Paclitaxel in Nanoparticles Alters Its Disposition

Yeh, T. K., Lu, Z., Wientjes, M. G., & Au, J. L. ‐. (2005) · Pharmaceutical Research · doi:10.1007/s11095-005-4581-4 · Cited by 90

Surfactant-Free, Biodegradable Nanoparticles for Aerosol Therapy Based on the Branched Polyesters, DEAPA-PVAL-g-PLGA

Dailey, L. A., Kleemann, E., Wittmar, M., Gessler, T., Schmehl, T., Roberts, C. J., Seeger, W., & Kissel, T. (2003) · Pharmaceutical Research · doi:10.1023/b:pham.0000008051.94834.10 · Cited by 90

Monoclonal antibody drug conjugates in the treatment of cancer

Trail, P. A., & Bianchi, A. B. (1999) · Current Opinion in Immunology · doi:10.1016/s0952-7915(99)00012-6 · Cited by 88

Distribution and Elimination of Coated Polymethyl [2-14C]Methacrylate Nanoparticles After Intravenous Injection in Rats

Leu, D., Manthey, B., Kreuter, J., Speiser, P. P., & Delucax, P. P. (1984) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600731028 · Cited by 88

Nanoparticles as Antituberculosis Drugs Carriers: Effect on Activity Against Mycobacterium tuberculosis in Human Monocyte-Derived Macrophages

Anisimova, Y. V., Gelperina, S. I., Peloquin, C. A., & Heifets, L. B. (2000) · Journal of Nanoparticle Research · doi:10.1023/a:1010061013365 · Cited by 87

Effervescent dry powder for respiratory drug delivery

Ely, L., Roa, W., Finlay, W. H., & Löbenberg, R. (2006) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2006.10.021 · Cited by 86

Evaluation of nanoparticles as drug-delivery systems. III: materials, stability, toxicity, possibilities of targeting, and use.

Kreuter, J. (1983) · PubMed · Cited by 82

Optimizing targeted gene delivery: Chemical modification of viral vectors and synthesis of artificial virus vector systems

Boeckle, S., & Wagner, E. (2006) · The AAPS Journal · doi:10.1208/aapsj080483 · Cited by 79

A New Powder Design Method to Improve Inhalation Efficiency of Pranlukast Hydrate Dry Powder Aerosols by Surface Modification with Hydroxypropylmethylcellulose Phthalate Nanospheres

Kawashima, Y., Serigano, T., Hino, T., Yamamoto, H., & Takeuchi, H. (1998) · Pharmaceutical Research · doi:10.1023/a:1011916930655 · Cited by 74

Uptake of PMMA nanoparticles from the gastrointestinal tract after oral administration to rats: modification of the body distribution after suspension in surfactant solutions and in oil vehicles

Araújo, L. C. D. P., Sheppard, M. A., Löbenberg, R., & Kreuter, J. (1999) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(98)00314-7 · Cited by 73

Macrophage Targeting of Azidothymidine: A Promising Strategy for AIDS Therapy*

Löbenberg, R., & Kreuter, J. (1996) · AIDS Research and Human Retroviruses · doi:10.1089/aid.1996.12.1709 · Cited by 70

Body distribution of azidothymidine bound to nanoparticles after oral administration

Löbenberg, R., Araújo, L. C. D. P., & Kreuter, J. (1997) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/s0939-6411(97)00078-7 · Cited by 67

Circulation Time and Body Distribution of 14C‐Labeled Amino‐Modified Polystyrene Nanoparticles in Mice

Simon, B. H., Ando, H. Y., & Gupta, P. K. (1995) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600841020 · Cited by 66

Targeted High Lung Concentrations of Itraconazole Using Nebulized Dispersions in a Murine Model

McConville, J. T., Overhoff, K. A., Sinswat, P., Vaughn, J. M., Frei, B. L., Burgess, D. S., Talbert, R. L., Peters, J. I., Johnston, K. P., & Williams, R. O. (2006) · Pharmaceutical Research · doi:10.1007/s11095-006-9904-6 · Cited by 65

A Useful In Vitro Model for Transport Studies of Alveolar Epithelial Barrier

Kim, K.-J., Borok, Z., & Crandall, E. D. (2001) · Pharmaceutical Research · doi:10.1023/a:1011040824988 · Cited by 64

Nanoparticle Based Systemic Gene Therapy for Lung Cancer: Molecular Mechanisms and Strategies to Suppress Nanoparticle-Mediated Inflammatory Response

Gopalan, B., Ito, I., Branch, C. D., Stephens, C. L., Roth, J. A., & Ramesh, R. (2004) · Technology in Cancer Research & Treatment · doi:10.1177/153303460400300615 · Cited by 59

Localization of colloidal particles (liposomes, hexylcyanoacrylate nanoparticles and albumin nanoparticles) by histology and autoradiography in mice

Waser, P. G., Müller, U., Kreuter, J., Berger, S., Munz, K., Kaiser, E., & Pfluger, B. (1987) · International Journal of Pharmaceutics · doi:10.1016/0378-5173(87)90219-5 · Cited by 58

Drug delivery and targeting

Illum, L. (2002) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(02)00260-0 · Cited by 52

Oral Therapy Using Nanoparticle-Encapsulated Antituberculosis Drugs in Guinea Pigs Infected with Mycobacterium tuberculosis

Johnson, C. M., Pandey, R., Sharma, S., Khuller, G. K., Basaraba, R. J., Orme, I. M., & Lenaerts, A. J. M. (2005) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.10.4335-4338.2005 · Cited by 49

Distribution of Polyhexyl Cyanoacrylate Nanoparticles in Nude Mice Bearing Human Osteosarcoma

Gipps, E. M., Arshady, R., Kreuter, J., Groscurth, P., & Speiser, P. P. (1986) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600750310 · Cited by 47

Preparation and Characterization of Novel Poly(methylidene Malonate 2.1.2.)-Made Nanoparticles

Lescure, F., Seguin, C., Breton, P., Bourrinet, P., Roy, D., & Couvreur, P. (1994) · Pharmaceutical Research · doi:10.1023/a:1018986226557 · Cited by 46

Chemotherapeutic Efficacy of Nanoparticle Encapsulated Antitubercular Drugs

Pandey, R., Sharma, S., & Khuller, G. K. (2006) · Drug Delivery · doi:10.1080/10717540500398076 · Cited by 46

Blood Clearance and Organ Distribution of Intravenously Administered Polymethacrylic Nanoparticles in Mice

Rolland, A. P., Collet, B., Verge, R. L., & Toujas, L. (1989) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600780613 · Cited by 43

Monoclonal antibodies and therapy of human cancers

Funaro, A., Horenstein, A. L., Santoro, P., Cinti, C., Gregorini, A., & Malavasi, F. (2000) · Biotechnology Advances · doi:10.1016/s0734-9750(00)00043-4 · Cited by 41

Doxorubicin magnetic conjugate targeting upon intravenous injection into mice: High gradient magnetic field inhibits the clearance of nanoparticles from the blood

Mykhaylyk, O. M., Dudchenko, N. O., & Dudchenko, A. K. (2005) · Journal of Magnetism and Magnetic Materials · doi:10.1016/j.jmmm.2005.01.063 · Cited by 41

Preparation and evaluation of bovine serum albumin nanospheres coated with monoclonal antibodies.

Akasaka, Y., Ueda, H., Takayama, K., Machida, Y., & NAGAI, T. (1988) · PubMed · Cited by 39

Study of Biodistribution of Methotrexate-Loaded Bovine Serum Albumin Nanospheres in Mice

Santhi, K., Dhanaraj, S. A., Koshy, M. K., Ponnusankar, S., & Suresh, B. (2000) · Drug Development and Industrial Pharmacy · doi:10.1081/ddc-100102311 · Cited by 34

Biophysical Investigation of Nanoparticle Interactions with Lung Surfactant Model Systems

Stuart, D., Löbenberg, R., Ku, T., Azarmi, S., Ely, L., Roa, W., & Prenner, E. J. (2006) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2006.031 · Cited by 30

Pulmonary Drug Delivery

(2000) · CRC Press eBooks · doi:10.1201/9780203483701.ch10 · Cited by 29

Technique for the rapid preparation of lung scan particles using 99mTc-sulfur and human serum albumin.

Cragin, M. D., Webber, M. M., Victery, W. K., & Pintauro, D. (1969) · PubMed · Cited by 23

Nanoparticles deliver RNAi therapy

Woodle, M. C., & Lu, P. Y. (2005) · Materials Today · doi:10.1016/s1369-7021(05)71035-x · Cited by 22

Effects of external magnetic field on biodistribution of nanoparticles: A histological study

Wu, T., Hua, M., Chen, J., Wei, K., Jung, S., Chang, Y.-J., Jou, M., & Ma, Y. (2007) · Journal of Magnetism and Magnetic Materials · doi:10.1016/j.jmmm.2006.10.1202 · Cited by 21

CT imaging of intrathoracic lymph nodes in dogs with bronchoscopically administered iodinated nanoparticles

Ketai, L. H., Muggenberg, B. A., McIntire, G. L., Bacon, E. R., Rosenberg, R., Losco, P. E., Toner, J. L., Nikula, K. J., & Haley, P. (1999) · Academic Radiology · doi:10.1016/s1076-6332(99)80061-0 · Cited by 17

Inhaled insulin: recent advances in the therapy of Type 1 and 2 diabetes

Quattrin, T. (2004) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.5.12.2597 · Cited by 15

Body Distribution of Nanoparticle-Containing Adriamycin Injected into the Hepatic Artery of Hepatoma-Bearing Rats

Chen, J., Wang, L., Ling, R., Li, Y., Wang, Z., Yao, Q., & Ma, Z. (2004) · Digestive Diseases and Sciences · doi:10.1023/b:ddas.0000037807.96064.99 · Cited by 13

mRNA-based therapeutics--developing a new class of drugs

Sahin, U., Karikó, K., & Türeci, Ö. (2014) · Nature Reviews Drug Discovery · doi:10.1038/nrd4278 · Cited by 2,474

Treating metastatic cancer with nanotechnology

Schroeder, A., Heller, D. A., Winslow, M. M., Dahlman, J. E., Pratt, G. W., Langer, R., Jacks, T., & Anderson, D. G. (2011) · Nature reviews. Cancer · doi:10.1038/nrc3180 · Cited by 1,175

DNA Nanotechnology-Enabled Drug Delivery Systems

Hu, Q., Li, H., Wang, L., Gu, H., & Fan, C. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00663 · Cited by 1,140

Size-Dependent In Vivo Transport of Nanoparticles: Implications for Delivery, Targeting, and Clearance

Xu, M., Qi, Y., Liu, G. H., Song, Y., Jiang, X., & Du, B. (2023) · ACS Nano · doi:10.1021/acsnano.3c05853 · Cited by 654

Solid Lipid Nanoparticles (SLN) and Nanostructured Lipid Carriers (NLC) for pulmonary application: A review of the state of the art

Weber, S., Zimmer, A., & Pardeike, J. (2013) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2013.08.013 · Cited by 579

Nanoparticle as An Emerging Tool in Pulmonary Drug Delivery System

Patel, P., Soni, T. G., Thakkar, V. T., & Gandhi, T. R. (2013) · Micro and Nanosystems · doi:10.2174/18764029113059990002 · Cited by 12

Trends in particulate antigen and DNA delivery systems for vaccines

Gander, B. A. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2004.10.002 · Cited by 14

Nanomedicine in pulmonary delivery

Das, S. C., Khadka, P., Shah, R., McGill, S. L., & Smyth, H. D. C. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-820466-5.00014-4 · Cited by 20

Nanoparticle-Mediated Pulmonary Drug Delivery: A Review

Paranjpe, M., & Müller-Goymann, C. C. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms15045852 · Cited by 467

Nanoparticles for drug delivery to the lungs

Sung, J. C., Pulliam, B., & Edwards, D. A. (2007) · Trends in biotechnology · doi:10.1016/j.tibtech.2007.09.005 · Cited by 659