Nanoparticles: Characteristics, Mechanisms of Action, and Toxicity in Pulmonary Drug Delivery—A Review
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The use of neutral nanoparticles as drug delivery vehicles is the most common approach in anti-TB therapy.
“The use of neutral NPs as drug delivery vehicles is the most common approach in anti-TB therapy.206”
From Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles (2019) · cites this paper as [206]
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Yang, W. P., Peters, J. I., & Williams, R. O. (2008) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2008.02.011 · Cited by 670 · see citing works
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Singh, A. P., Biswas, A., Shukla, A., & Maiti, P. (2019) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-019-0068-3 · Cited by 645 · see citing works
“The use of neutral NPs as drug delivery vehicles is the most common approach in anti-TB therapy.(206) Ciprofloxacin encapsulated in liposomes has been employed in anti-TB therapy, offering pulmonary delivery through nebulization.”
MethodTargeted delivery of nanoparticles for the treatment of lung diseases
Azarmi, S., Roa, W. H., & Löbenberg, R. (2008) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2007.11.006 · Cited by 440 · see citing works
Self-citationAbdelaziz, H. M., Gaber, M. K., Elwakil, M. M. A., Mabrouk, M. T., Elgohary, M. M., Kamel, N. M., Kabary, D. M., Freag, M. S., Samaha, M. W., Mortada, S. M., et al. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.11.036 · Cited by 409 · see citing works
Drug nanocrystals: in vivo performances.
Gao, L., Liu, G., Ma, J., Wang, X., Zhou, L., & Li, X. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.03.013 · Cited by 347 · see citing works
New old challenges in tuberculosis: Potentially effective nanotechnologies in drug delivery
Sosnik, A., Carcaboso, A. M., Glisoni, R. J., Moretton, M. A., & Chiappetta, D. A. (2009) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2009.11.023 · Cited by 264 · see citing works
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Zhang, J., Wu, L., Chan, H., & Watanabe, W. (2010) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2010.11.002 · Cited by 210 · see citing works
Shukla, R., Nune, S. K., Chanda, N., et al. (2008) · Small · doi:10.1002/smll.200800525 · Cited by 201 · see citing works
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Beck-Broichsitter, M., Merkel, O. M., & Kissel, T. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.12.004 · Cited by 200 · see citing works
Inhalable nanoparticles, a non-invasive approach to treat lung cancer in a mouse model
Roa, W., Azarmi, S., Alhallak, K., Finlay, W. H., Magliocco, A. M., & Löbenberg, R. (2010) · Journal of Controlled Release · doi:10.1016/j.jconrel.2010.10.035 · Cited by 181 · see citing works
Self-citationPoh, T. Y., Ali, N. A. B. M., Aogáin, M. M., Kathawala, M. H., Setyawati, M. I., Ng, K. W., & Chotirmall, S. H. (2018) · Particle and Fibre Toxicology · doi:10.1186/s12989-018-0282-0 · Cited by 172 · see citing works
Pharmaceutical strategies to extend pulmonary exposure of inhaled medicines
Guo, Y., Bera, H., Shi, C., Zhang, L., Cun, D., & Yang, M. (2021) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2021.05.015 · Cited by 172 · see citing works
Nanoparticulate drug delivery systems for cancer chemotherapy
Saha, R. N., Sekar, V., Bende, G., & Snehalatha, M. (2010) · Molecular Membrane Biology · doi:10.3109/09687688.2010.510804 · Cited by 163 · see citing works
“It is expected that within 10 years, 50% of all drug delivery and design approaches may be shifted to Nanoparticulate Drug Delivery Systems (NPDDS) technology (Gill et al. 2007).”
BackgroundInfluentialPeng, C., Chen, L., & Tang, M. (2021) · Fundamental Research · doi:10.1016/j.fmre.2021.11.021 · Cited by 164 · see citing works
Nano-QSAR modeling for predicting biological activity of diverse nanomaterials
Singh, K. P., & Gupta, S. (2014) · RSC Advances · doi:10.1039/c4ra01274g · Cited by 152 · see citing works
Translational nanomedicine: status assessment and opportunities
Murday, J. S., Siegel, R. W., Stein, J. A., & Wright, J. F. (2009) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2009.06.001 · Cited by 146 · see citing works
Spray freeze drying for dry powder inhalation of nanoparticles
Ali, M. E., & Lamprecht, A. (2014) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2014.03.009 · Cited by 143 · see citing works
Ciprofloxacin-loaded PLGA nanoparticles against cystic fibrosis P. aeruginosa lung infections
Günday-Türeli, N., Torge, A., Juntke, J., Schwarz, B., Schneider‐Daum, N., Türeli, A. E., Lehr, C., & Schneider, M. (2017) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2017.04.032 · Cited by 133 · see citing works
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Costa, A., Pinheiro, M., Magalhães, J., Ribeiro, R., Seabra, V., Reis, S., & Sarmento, B. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2016.04.012 · Cited by 123 · see citing works
Micro- and nanocarrier-mediated lung targeting
Kurmi, B. D., Kayat, J., Gajbhiye, V., Tekade, R. K., & Jain, N. K. (2010) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2010.492212 · Cited by 122 · see citing works
“Drug delivery to lungs is an attractive horizon owing to the large surface area of the alveolar region, lower thickness of the epithelial barrier, extensive vascularization, relatively low proteolytic activity in the alveolar space as compared with other routes of administration and absence of the first-pass metabolis…”
BackgroundBiphasic release of gentamicin from chitosan/fucoidan nanoparticles for pulmonary delivery
Huang, Y., Li, R., Chen, J.-Y., & Chen, J. (2015) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2015.11.072 · Cited by 123 · see citing works
“The proposed mechnism of NP deposition is Brownian diffusion, which occurs in the cinar region of the lungs (Gill et al., 2007).”
BackgroundRespirable nanocarriers as a promising strategy for antitubercular drug delivery
Mehanna, M. M., Mohyeldin, S. M., & Elgindy, N. A. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.05.038 · Cited by 119 · see citing works
Beck‐Broichsitter, M., Ruppert, C., Schmehl, T., Guenther, A., Betz, T., Bakowsky, U., Seeger, W., Kissel, T., & Gessler, T. (2010) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2010.10.007 · Cited by 116 · see citing works
Liposomes as Drug Delivery Systems for The Treatment of TB
Pinheiro, M., Lúcio, M., Lima, J. L. F. C., & Reis, S. (2011) · Nanomedicine · doi:10.2217/nnm.11.122 · Cited by 115 · see citing works
Recent applications and strategies in nanotechnology for lung diseases
Zhong, W., Zhang, X., Zeng, Y., Lin, D., & Wu, J. (2021) · Nano Research · doi:10.1007/s12274-020-3180-3 · Cited by 115 · see citing works
Biodistribution of Amikacin Solid Lipid Nanoparticles after Pulmonary Delivery
Varshosaz, J., Ghaffari, S., Mirshojaei, S. F., Jafarian‐Dehkordi, A., Atyabi, F., Kobarfard, F., & Azarmi, S. (2013) · BioMed Research International · doi:10.1155/2013/136859 · Cited by 110 · see citing works
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BackgroundSelf-citationMeenach, S. A., Anderson, K. W., Hilt, J. Z., McGarry, R. C., & Mansour, H. M. (2013) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2013.05.012 · Cited by 110 · see citing works
Inhaled nanoparticles–An updated review
Praphawatvet, T., Peters, J. I., & Williams, R. O. (2020) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2020.119671 · Cited by 101 · see citing works
Jyoti, K., Kaur, K., Pandey, R. S., Jain, U. K., Chandra, R., & Madan, J. (2015) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2014.12.092 · Cited by 82 · see citing works
Advances in Device and Formulation Technologies for Pulmonary Drug Delivery
Chan, J. G. Y., Wong, J., Zhou, Q. T., Leung, S. S. Y., & Chan, H. (2014) · AAPS PharmSciTech · doi:10.1208/s12249-014-0114-y · Cited by 82 · see citing works
“ability, chemical composition, particle size, and local concentration (123, 124).”
Mansour, H. M., Meenach, S. A., Vogt, McGarry, Anderson, �., & Hilt, J. Z. (2013) · International Journal of Nanomedicine · doi:10.2147/ijn.s30724 · Cited by 77 · see citing works
“Synthetic DPPC (molecular weight 734.039 g/mol, .”
InfluentialNejati‐Koshki, K., Abbasi, M. M., Ebrahimi, E., et al. (2014) · Journal of Microencapsulation · doi:10.3109/02652048.2014.940011 · Cited by 76 · see citing works
“, 2007) including second-hand smoke (Gill et al., 2007; Roy et al., 2011).”
BackgroundBeck‐Broichsitter, M., Ruppert, C., Schmehl, T., et al. (2013) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2013.10.016 · Cited by 66 · see citing works
Sabir, F., Qindeel, M., Zeeshan, M., Ain, Q. U., Rahdar, A., Barani, M., González, E., & Aboudzadeh, M. A. (2021) · Processes · doi:10.3390/pr9040621 · Cited by 55 · see citing works
“Nanoparticles produce pulmonary toxicity by oxidative stress because of the production of reactive oxygen species within the biological system [137].”
BackgroundBalde, A., Kim, S., Benjakul, S., & Nazeer, R. A. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.09.116 · Cited by 52 · see citing works
Günday-Türeli, N., Türeli, A. E., & Schneider, M. (2016) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2016.10.025 · Cited by 47 · see citing works
Farcal, L. R., Uboldi, C., Méhn, D., Giudetti, G., Nativo, P., Ponti, J., Gilliland, D. D., Rossi, F., & Bal‐Price, A. (2012) · Nanotoxicology · doi:10.3109/17435390.2012.710658 · Cited by 46 · see citing works
“strated that the unique physiochemical properties of nanoparticles are attributed to their small size, large surface area, chemical composition, surface reactivity, charge, shape and interactions with different kinds of proteins (Oberdorster et al. 2005; Gill et al. 2007).”
BackgroundAlhallak, K., Azarmi, S., Anwar‐Mohamed, A., Roa, W., & Löbenberg, R. (2010) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2010.05.002 · Cited by 45 · see citing works
“The lungs, as a part of the MPS, are extensively rich in alveolar macrophages [10].”
BackgroundSelf-citationWang, Q., Guan, Y., Yao, S., et al. (2010) · The Journal of Supercritical Fluids · doi:10.1016/j.supflu.2010.12.002 · Cited by 44 · see citing works
Gupta, C., Jaipuria, A., & Gupta, N. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics15010139 · Cited by 43 · see citing works
“One major risk involved is pulmonary toxicity due to the high concentration of drugs in the lungs [14].”
BackgroundAbuelella, K. E., Abd-Allah, H., Soliman, S. M., et al. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.123458 · Cited by 43 · see citing works
Formulating protein therapeutics into particulate forms
Yang, S., Yuan, W., & Jin, T. (2009) · Expert Opinion on Drug Delivery · doi:10.1517/17425240903156374 · Cited by 43 · see citing works
“To ensure that therapeutics reach pulmonary alveoli (which represent sufficient area of mucosa), protein-loading particles have to be formulated in the range of 1 – 5 μm in diameter so that they can be carried in by the airflow of respiration to the destination without earlier deposition and exhalation [3,4].”
BackgroundGulin-Sarfraz, T., Jonasson, S., Wigenstam, E., et al. (2019) · Pharmaceutics · doi:10.3390/pharmaceutics11040149 · Cited by 41 · see citing works
“Drug-loaded particles, compared to free drugs, also have a higher ability to reach the lower parts of the lungs [26,27].”
BackgroundPulmonary delivery of anti-inflammatory agents
Ali, M. E., McConville, J. T., & Lamprecht, A. (2014) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2015.993968 · Cited by 37 · see citing works
“Pulmonary drug delivery has many advantages over other routes of drug administration and drug absorption, including the large alveolar surface area, extensive vascularization (about 5 l/min), low thickness of the epithelial barrier and the limited enzymatic activity compared to other routes of administration [7-9].”
BackgroundPulmonary Toxicity of Polysorbate-80-coated Inhalable Nanoparticles; In vitro and In vivo Evaluation
Alhallak, K., Azarmi, S., Sun, C., Lai, P. K., Prenner, E. J., Roa, W., & Löbenberg, R. (2010) · The AAPS Journal · doi:10.1208/s12248-010-9190-4 · Cited by 37 · see citing works
Self-citationBeck‐Broichsitter, M., Schmehl, T., Seeger, W., & Gessler, T. (2010) · Journal of Nanomaterials · doi:10.1155/2011/163791 · Cited by 36 · see citing works
“However, the relevance of these findings for the in vivo translocation of inhaled ultrafine particles remains to be established, owing to the fact that polymeric nanoparticles are currently under investigation as potential drug delivery systems to the lung [95].”
BackgroundRelease, Characterization, and Safety of Nanoencapsulated Food Ingredients
Jafari, S. M., Esfanjani, A. F., Katouzian, I., & Assadpour, E. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809740-3.00010-6 · Cited by 49 · see citing works
Targeted delivery of anti-tuberculosis drugs to macrophages: targeting mannose receptors
Filatova, L. Y., Klyachko, N. L., & Kudryashova, E. V. (2018) · Russian Chemical Reviews · doi:10.1070/rcr4740 · Cited by 35 · see citing works
Current advances in drug delivery of nanoparticles for respiratory disease treatment
de Menezes, B. R. C., Rodrigues, K. F., Schatkoski, V. M., Pereira, R. M., Ribas, R. G., Montanheiro, T. L. D. A., & Thim, G. P. (2020) · Journal of Materials Chemistry B · doi:10.1039/d0tb01783c · Cited by 34 · see citing works
Ebrahimi, S., Shamloo, A., Alishiri, M., Mofrad, Y. M., & Akherati, F. (2021) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2021.121133 · Cited by 34 · see citing works
Nanogold-Gallate Chitosan-Targeted Pulmonary Delivery for Treatment of Lung Cancer
Komenek, S., Luesakul, U., Ekgasit, S., et al. (2016) · AAPS PharmSciTech · doi:10.1208/s12249-016-0644-6 · Cited by 34 · see citing works
Deposition of Inhaled Ultrafine Aerosols in Replicas of Nasal Airways of Infants
Golshahi, L., Finlay, W. H., Olfert, J. S. S., et al. (2010) · Aerosol Science and Technology · doi:10.1080/02786826.2010.488256 · Cited by 31 · see citing works
“Nanomedicine, including the use of nanoparticles, has potential for the therapeutic treatment of diseases via manipulation of particle characteristics such as size, surface chemistry, surface charge, and surface area (Gill et al. 2007).”
Polymeric Nanoparticles for Inhaled Vaccines
Al‐Nemrawi, N. K., Darweesh, R. S., Alshriem, L. A., Al-Qawasmi, F. S., Emran, S. O., Khafajah, A. S., & Abu‐Dalo, M. (2022) · Polymers · doi:10.3390/polym14204450 · Cited by 30 · see citing works
Anti-SARS-CoV-1 and −2 nanobody engineering towards avidity-inspired therapeutics
Obeng, E. M., Dzuvor, C. K. O., & Danquah, M. K. (2021) · Nano Today · doi:10.1016/j.nantod.2021.101350 · Cited by 26 · see citing works
Liposomes-and niosomes-based drug delivery systems for tuberculosis treatment
Bekraki, A. I. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819811-7.00007-2 · Cited by 28 · see citing works
Aptamers as promising nanotheranostic tools in the COVID ‐19 pandemic era
Dzuvor, C. K. O., Tettey, E. L., & Danquah, M. K. (2022) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1785 · Cited by 25 · see citing works
“In addition, these platforms possess superb bioavailability, longer blood circulatory properties, and pharmacokinetics profile (Gill et al., 2007; Li et al., 2018), which makes them perfect for curbing lung-related or respiratory diseases of which COVID-19 is no exception.”
BackgroundBouzas, V., Haller, T., Hobi, N., Felder, E., Pastoriza‐Santos, I., & Pérez‐Gil, J. (2013) · Nanotoxicology · doi:10.3109/17435390.2013.829878 · Cited by 25 · see citing works
“The size of NPs is the critical parameter that defines the site of deposition within the respiratory tract (Gill et al. 2007).”
BackgroundYadav, K. S., Upadhya, A., & Misra, A. R. (2020) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2021.1832989 · Cited by 24 · see citing works
State of the Art of Nanobiotechnology Applications in Neglected Diseases
Durán, N., Marcato, P. D., Teixeira, Z., Durán, M., Costa, F. T. M., & Brocchi, M. (2009) · Current Nanoscience · doi:10.2174/157341309789378069 · Cited by 23 · see citing works
“Nanotechnology in the field of pharmaceutical biotechnology has had a positive influence on medical and pharmaceutical sciences [1-7].”
BackgroundBiogenic Nano-Synthesis; towards the Efficient Production of the Biocompatible Gold Nanoparticles
Gajanan, G., Eom, C., Kim, S. W., et al. (2010) · Bulletin of the Korean Chemical Society · doi:10.5012/bkcs.2010.31.10.2771 · Cited by 23 · see citing works
DRUG-RESISTANT TUBERCULOSIS: RECENT APPROACH IN POLYMER BASED NANOMEDICINE
Shaji, J., & Shaikh, M. (2016) · International Journal of Pharmacy and Pharmaceutical Sciences · doi:10.22159/ijpps.2016v8i10.11295 · Cited by 21 · see citing works
“Moreover, the NPs can be engineered by attaching different ligands for active targeting of an area of interest like alveolar macrophages (AMs) [43].”
BackgroundDon, T., Hong, Y., Jheng, P., Chuang, E., & Huang, Y.-C. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.133901 · Cited by 21 · see citing works
Relevance of Two-Dimensional Brownian Motion Dynamics in Applying Nanoparticle Tracking Analysis
der Meeren, P. V., Kasinos, M., & Saveyn, H. G. M. (2012) · Methods in molecular biology · doi:10.1007/978-1-61779-953-2_42 · Cited by 21 · see citing works
Biocompatible Nanovesicular Drug Delivery Systems with Targeting Potential for Autoimmune Diseases
Neupane, Y. R., Mahtab, A., Siddiqui, L., Singh, A., Gautam, N., Rabbani, S. A., Goel, H., & Talegaonkar, S. (2020) · Current Pharmaceutical Design · doi:10.2174/1381612826666200523174108 · Cited by 21 · see citing works
High-voltage, electric field-driven micro/nanofabrication for polymeric drug delivery systems
Xie, Y., & Castracane, J. (2009) · IEEE Engineering in Medicine and Biology Magazine · doi:10.1109/memb.2008.931013 · Cited by 20 · see citing works
Core–shell drug carriers: liposomes, polymersomes, and niosomes
Dan, N. R. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-46143-6.00002-6 · Cited by 21 · see citing works
Ali, R., Mittal, G., Ali, R., et al. (2013) · Journal of Microencapsulation · doi:10.3109/02652048.2013.764937 · Cited by 18 · see citing works
“…Carvalho et al., 2011), local action, low enzyme activity, immediate therapeutic concentration at low dose, high safety index and increased patient compliance due to non-invasive nature (Gill et al., 2007; Mansour et al., 2009) makes it a preferred route for treating various respiratory disorders.”
BackgroundCastanha, R. F., Pereira, A. D. E. S., Villarreal, G. P. U., et al. (2023) · Environmental Pollution · doi:10.1016/j.envpol.2023.122235 · Cited by 17 · see citing works
Harnessing sortase A transpeptidation for advanced targeted therapeutics and vaccine engineering
Obeng, E. M., Fulcher, A. J., & Wagstaff, K. M. (2023) · Biotechnology Advances · doi:10.1016/j.biotechadv.2023.108108 · Cited by 20 · see citing works
Saghravanian, M., Ebrahimi, M., Es’haghi, Z., et al. (2017) · South African Journal of Chemistry · doi:10.17159/0379-4350/2017/v70a5 · Cited by 17 · see citing works
Modern Strategies of Drug Therapy: Multi-Target Drug Delivery, Bioimaging, Diagnostics
Fedorova, O. V., Ovchinnikova, I. G., Rusinov, G. L., Avdeeva, V. V., Zhdanov, А. P., Zhizhin, K. Y., Kuznetsov, N. T., Zakharova, L. Y., Kuznetsova, D. A., Razuvayeva, Y. S., et al. (2025) · Russian Journal of General Chemistry · doi:10.1134/s1070363225606726 · Cited by 15 · see citing works
CHACHULI, S. H. M., Nawaz, A., Shah, K. U., et al. (2016) · Pharmaceutical Research · doi:10.1007/s11095-016-1893-5 · Cited by 14 · see citing works
Soltani, M., Karami‐Mohajeri, S., Ranjbar, M., Ahmadi, N., Jafari, E., Mandegari, A., & Heydari, M. R. (2023) · Ceramics International · doi:10.1016/j.ceramint.2023.01.069 · Cited by 13 · see citing works
Günday-Türeli, N., Türeli, A. E., & Schneider, M. (2014) · Drug Delivery Letters · doi:10.2174/2210303104666140222002101 · Cited by 12 · see citing works
Dan, N. R. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813627-0.00001-6 · Cited by 14 · see citing works
Radiation Protection with Nanoparticles
Baker, C. H. (2011) · Science Publishers eBooks · doi:10.1201/b11076-15 · Cited by 12 · see citing works
Nie, Q., Wang, C., Xu, H., Mittal, P., Naeem, A., Zhou, P., Li, H., Zhang, Y., Guo, T., Sun, L., et al. (2023) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2023.104296 · Cited by 13 · see citing works
Rajendran, R., Rajan, B., Ganesan, N., & Devaki, T. (2015) · International Journal of Pharmacy and Pharmaceutical Sciences · Cited by 10 · see citing works
Nanocarrier-Assisted Antimicrobial Therapy Against Intracellular Pathogens
Kumar, L., Verma, S., Vaidya, B., & Mehra, N. K. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-46152-8.00013-5 · Cited by 11 · see citing works
Nguyen, H. X. (2019) · Springer eBooks · doi:10.1007/978-3-030-06115-9_17 · Cited by 11 · see citing works
Duan, L., Shirazian, S., & Zare, M. H. (2024) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2024.124680 · Cited by 12 · see citing works
Mao, C.-N., Malek, K. A., & Asa-Awuku, A. (2021) · Aerosol Science and Technology · doi:10.1080/02786826.2021.1931012 · Cited by 9 · see citing works
“Additionally, organic nano-particles are intentionally produced and inhaled for aerosol therapy (Muralidharan et al. 2015; Azarmi, Roa, and L€obenberg 2008; Gill et al. 2007; Agnihotri, Mallikarjuna, and Aminabhavi 2004; Malcolmson and Embleton 1998).”
BackgroundAbuelella, K. E., Mosallam, S., El-Gazar, A. A., et al. (2025) · Journal of Pharmaceutical Innovation · doi:10.1007/s12247-025-10240-z · Cited by 7 · see citing works
Daear, W., Sule, K., Lai, P. K., & Prenner, E. J. (2022) · RSC Advances · doi:10.1039/d2ra02859j · Cited by 7 · see citing works
Self-citationShushkov, P., Tzvetanov, S., Ivanova, A., et al. (2008) · Langmuir · doi:10.1021/la703616c · Cited by 7 · see citing works
Nanocrystals based mucosal delivery system: research advances
Liu, Y., Shuai, S., Huang, G. S., Chen, Y., Shen, B., & Yue, P. (2021) · Drug Development and Industrial Pharmacy · doi:10.1080/03639045.2022.2053985 · Cited by 6 · see citing works
Kan, S., Grainge, C., Nichol, K., Reid, A. T., Knight, D. A., Sun, Y. J., Bartlett, N. W., & Liang, M. (2022) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2022.121586 · Cited by 6 · see citing works
Nanoparticle Functionalization for Brain Targeting Drug Delivery and Diagnostic
Gomes, M. J., Mendes, B. B., Martins, S., & Sarmento, B. F. C. C. (2015) · Springer eBooks · doi:10.1007/978-3-319-15338-4_42 · Cited by 6 · see citing works
Kim, S.-Y., Kim, S.-Y., Kang, M.-K., et al. (2026) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2026.115592 · Cited by 4 · see citing works
Dondulkar, A., Akojwar, N., Katta, C. B., Khatri, D. K., Mehra, N. K., Singh, S. B., & Madan, J. (2021) · Current Pharmaceutical Design · doi:10.2174/1381612827666211104155604 · Cited by 4 · see citing works
Pulmonary Drug Delivery with Nanoparticles
Beck‐Broichsitter, M., Schmehl, T., Seeger, W., & Gessler, T. (2011) · Science Publishers eBooks · doi:10.1201/b11076-13 · Cited by 4 · see citing works
Nanomedicines in Tuberculosis: Diagnosis, Therapy and Nanodrug Delivery
Dakkah, A. N., Bataineh, Y. A., Al-Jaidi, B. A., Bayan, M. F., & Nimer, N. A. (2020) · Engineering materials · doi:10.1007/978-3-030-36260-7_13 · Cited by 3 · see citing works
Development and Characterization of Nanocarrier Systems for the Delivery of Antitubercular Drugs
Ribeiro, R. (2013) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) · doi:10.34626/b6v3-t472 · Cited by 3 · see citing works
Carbon Dots with Tunable Charge as Mucus-Penetrating Gene Carriers
Arca, S., Witjaksono, C., Pons, F., & Lebeau, L. (2025) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2025.107222 · Cited by 4 · see citing works
Yang, W. P. (2009) · Texas ScholarWorks (Texas Digital Library) · Cited by 2 · see citing works
Applications of pulsed laser ablation for enhanced gold nanofluids
Hur, T.-B., Phuoc, T. X., Chyu, M. K., et al. (2012) · Journal of Applied Physics · doi:10.1063/1.4752876 · Cited by 2 · see citing works
Rasulev, B., Leszczyńska, D., & Leszczyński, J. (2011) · IGI Global eBooks · doi:10.4018/978-1-60960-860-6.ch003 · Cited by 2 · see citing works
“…experiments are published in the last few years (Choi et al, 2008; Lewinski et al, 2008; Franklin et al, 2007; Duffin et al, 2007; Fiorito, 2007; Gill et al, 2007;Powers et al, 2007; Medina et al, 2007; Moore, 2006; Karakoti et al, 2006; Moss & Wong, 2006; Lee & Cho, 2006; Tsuji et al, 2006;…”
BackgroundToxicological Aspects of Polymer Nanoparticles
Irache, J. M., Martín‐Arbella, N., Ojer, P., Azqueta, A., & de Ceráin, A. L. (2016) · Springer eBooks · doi:10.1007/978-3-319-41421-8_16 · Cited by 4 · see citing works
Yurdasiper, A., Arıcı, M., & Özyazıcı, M. (2018) · Elsevier eBooks · doi:10.1016/b978-0-323-40016-9.00007-5 · Cited by 2 · see citing works
Asymmetric particles for pulmonary drug delivery
Köhler, D. (2010) · Max Planck Institute for Plasma Physics · doi:10.22028/d291-22691 · Cited by 2 · see citing works
“1μm in the alveoli) make the lung an interesting drug delivery route due to the high drug absorption and the ability to circumvent the first pass effect [7, 8].”
Background
- Authors
- Gill, S., Löbenberg, R., Ku, T., Azarmi, S., Roa, W., & Prenner, E. J.
- Venue
- Journal of Biomedical Nanotechnology
- Publisher
- American Scientific Publishers
- Published
- 2007-06-01
- Volume
- 3
- Issue
- 2
- Pages
- 107-119
- ISSN
- 1550-7033 (ISSN-L)
- 0000-0000
- OpenAlex
- W2329541536
- Cited by
- 118
- References
- 0
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 4 · 2023: 6 · 2022: 7 · 2021: 9 · 2020: 6 · 2019: 5 · 2018: 4 · 2017: 6 · 2016: 8 · 2015: 5 · 2014: 8 · 2013: 7 · 2012: 7
- FWCI
- 6.60
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Biomedical Nanotechnology (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Inhalation and Respiratory Drug Delivery
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
- Keywords
- nanoparticles, pulmonary drug delivery, mechanism of action, nanoparticle toxicity, aerosolized nanoparticles, lung deposition
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