Cited by 440Inhalation and Respiratory Drug DeliveryNanoparticle-Based Drug DeliveryAdvanced Drug Delivery Systems

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Targeted delivery of nanoparticles for the treatment of lung diseases

Azarmi, Shirzad, Roa, Wilson H., Löbenberg, Raimar·2008·Advanced Drug Delivery Reviews

DOI 10.1016/j.addr.2007.11.006

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Abstract

Targeted delivery of drug molecules to organs or special sites is one of the most challenging research areas in pharmaceutical sciences. By developing colloidal delivery systems such as liposomes, micelles and nanoparticles a new frontier was opened for improving drug delivery. Nanoparticles with their special characteristics such as small particle size, large surface area and the capability of changing their surface properties have numerous advantages compared with other delivery systems. Targeted nanoparticle delivery to the lungs is an emerging area of interest. This article reviews research performed over the last decades on the application of nanoparticles administered via different routes of administration for treatment or diagnostic purposes. Nanotoxicological aspects of pulmonary delivery are also discussed.

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Continuous cultures of fused cells secreting antibody of predefined specificity
Köhler, G., & Milstein, C. (1975) · Nature · doi:10.1038/256495a0 · Cited by 17,200
Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy
Oberdörster, G., Maynard, A., Donaldson, K., Castranova, V., Fitzpatrick, J., Ausman, K., Carter, J., Karn, B., Kreyling, W., Lai, D., et al. (2005) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-2-8 · Cited by 2,134
Drug Delivery and Targeting
Hillery, A. M., Lloyd, A. W., & Swarbrick, J. (2016) · CRC Press eBooks · doi:10.1201/b12801 · Cited by 2,031
Comparison of the Abilities of Ambient and Manufactured Nanoparticles To Induce Cellular Toxicity According to an Oxidative Stress Paradigm
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Comparative Pulmonary Toxicity Assessment of Single-wall Carbon Nanotubes in Rats
Warheit, D. B. (2003) · Toxicological Sciences · doi:10.1093/toxsci/kfg228 · Cited by 1,531
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Edwards, D. A., Hanes, J. S., Caponetti, G., Hrkach, J. S., Ben-Jebria, A., Eskew, M. L., Mintzes, J. D., Deaver, D. R., Lotan, N., & Langer, R. (1997) · Science · doi:10.1126/science.276.5320.1868 · Cited by 1,184
Nanoparticle Uptake by the Rat Gastrointestinal Mucosa: Quantitation and Particle Size Dependency
Jani, P., Halbert, G. W., Langridge, J., & Florence, A. T. (1990) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1990.tb07033.x · Cited by 920
Assessing Toxicity of Fine and Nanoparticles: Comparing In Vitro Measurements to In Vivo Pulmonary Toxicity Profiles
Sayes, C. M., Reed, K. L., & Warheit, D. B. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfm018 · Cited by 769
The Potential Advantages of Nanoparticle Drug Delivery Systems in Chemotherapy of Tuberculosis
Gelperina, S. E., Kisich, K. O., Iseman, M. D., & Heifets, L. B. (2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200504-613pp · Cited by 744
Abraxane®, a novel Cremophor®-free, albumin-bound particle form of paclitaxel for the treatment of advanced non-small-cell lung cancer
Green, M. R., Manikhas, G. M., Орлов, С. В., Afanasyev, B. V., Makhson, A. M., Bhar, P., & Hawkins, M. (2006) · Annals of Oncology · doi:10.1093/annonc/mdl104 · Cited by 671

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Clark, 2002, Formulation of proteins and peptides for inhalation, Drug Deliv. Syst. Sci., 2, 73
Page, 1996, Entrapment of colistin into polyhexylcyanoacrylate nanoparticles: preparation, drug release and tissue distribution in mice, S.T.P. Pharm. Sci., 6, 298
Leucuta, 2003, Preparation and pharmaceutical/pharmacokinetic characterization of liposomes and nanoparticles loaded with epirubicin, S.T.P. Pharm. Sci., 13, 291
Shvedova, 2003, Exposure to carbon nanotube material: evidence of exposure-induced oxidant stress in human keratinocyte and bronchial epithelial cells, Free Radic. Res., 37, 97

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Tian, G., Longest, P. W., Su, G., & Hindle, M. (2010) · Annals of Biomedical Engineering · doi:10.1007/s10439-010-0223-z · Cited by 92
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Stocke, N. A., Meenach, S. A., Arnold, S. M., Mansour, H. M., & Hilt, J. Z. (2014) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2014.12.050 · Cited by 91
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Liu, Y., Ibricevic, A., Cohen, J. A., Cohen, J. L., Gunsten, S. P., Fréchet, J. M. J., Walter, M. J., Welch, M. J., & Brody, S. L. (2009) · Molecular Pharmaceutics · doi:10.1021/mp900215p · Cited by 91
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Harush-Frenkel, O., Bivas‐Benita, M., Nassar, T., Springer, C., Sherman, Y., Avital, A., Altschuler, Y., Borlak, J. T., & Benita, S. (2010) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2010.04.011 · Cited by 88
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Hua, M., Yang, H., Liu, H.-L., Tsai, R., Pang, S., Chuang, K., Chang, Y., Hwang, T., Chang, Y., Chuang, H., et al. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.08.014 · Cited by 85
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Chai, M., Gao, Y., Liu, J., Deng, Y., Hu, D., Jin, Q., & Ji, J. (2020) · Advanced Healthcare Materials · doi:10.1002/adhm.201901542 · Cited by 85
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Yang, H., Hua, M., Liu, H.-L., Huang, C.-Y., Tsai, R., Lin, Y.-J., Chen, J., Tang, H.-J., Hsien, H.-Y., Chang, Y., et al. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.05.047 · Cited by 85
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Jyoti, K., Kaur, K., Pandey, R. S., Jain, U. K., Chandra, R., & Madan, J. (2015) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2014.12.092 · Cited by 85
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Chan, J. G. Y., Wong, J., Zhou, Q. T., Leung, S. S. Y., & Chan, H. (2014) · AAPS PharmSciTech · doi:10.1208/s12249-014-0114-y · Cited by 82
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Thomas, D., Kurienthomas, K., & Latha, M. S. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.03.167 · Cited by 80
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Yue, L., Zhang, X., Zhao, C., Chen, R., Chen, X. S., & Rao, L. (2023) · Nano Today · doi:10.1016/j.nantod.2023.101942 · Cited by 84
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Authors: Azarmi, S., Roa, W. H., & Löbenberg, R.
Affiliations: University of Alberta (CA)
Corresponding author: Löbenberg, Raimar
ORCID: Roa, Wilson H.
Löbenberg, Raimar
Venue: Advanced Drug Delivery Reviews
Publisher: Elsevier BV
Published: 2008-05
Volume: 60
Issue: 8
Pages: 863-875
ISSN: 0169-409X (ISSN-L)
DOI: 10.1016/j.addr.2007.11.006
OpenAlex: W1972609612
Cited by: 440
References: 99
Citations by year: 2026: 11 · 2025: 12 · 2024: 22 · 2023: 25 · 2022: 27 · 2021: 25 · 2020: 24 · 2019: 23 · 2018: 18 · 2017: 21 · 2016: 27 · 2015: 28 · 2014: 35 · 2013: 25 · 2012: 33
FWCI: 4.33
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Advanced Drug Delivery Reviews (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Inhalation and Respiratory Drug Delivery
Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
Keywords: targeted drug delivery, nanoparticles, lung disease, pulmonary drug delivery, liposomes, micelles, colloidal drug delivery systems, route of administration, nanotoxicology
MeSH terms: Animals, Antibodies, Monoclonal, Humans, Lung, Lung Diseases, Magnetics, Drug Delivery Systems, Gene Transfer Techniques, Nanoparticles

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