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Cited by 250

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Reservoir-based drug delivery systems utilizing microtechnology

Open access
Stevenson, Cynthia L., Santini, John T., Langer, Robert·2012·Advanced Drug Delivery Reviews

Abstract

This review covers reservoir-based drug delivery systems that incorporate microtechnology, with an emphasis on oral, dermal, and implantable systems. Key features of each technology are highlighted such as working principles, fabrication methods, dimensional constraints, and performance criteria. Reservoir-based systems include a subset of microfabricated drug delivery systems and provide unique advantages. Reservoirs, whether external to the body or implanted, provide a well-controlled environment for a drug formulation, allowing increased drug stability and prolonged delivery times. Reservoir systems have the flexibility to accommodate various delivery schemes, including zero order, pulsatile, and on demand dosing, as opposed to a standard sustained release profile. Furthermore, the development of reservoir-based systems for targeted delivery for difficult to treat applications (e.g., ocular) has resulted in potential platforms for patient therapy.

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Registry

Crossref · 10.1016/j.addr.2012.02.005

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Metadata

Authors
Stevenson, C. L., Santini, J. T., & Langer, R.
Venue
Advanced Drug Delivery Reviews
Publisher
Elsevier BV
Published
2012-11
Volume
64
Issue
14
Pages
1590-1602
ISSN
0169-409X (ISSN-L)
OpenAlex
W2056647619
Cited by
250
References
4
FWCI
2.46
Type
journal article
Language
en
Open access
green

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.