Nanotechnology and pulmonary delivery to overcome resistance in infectious diseases

Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles

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Polymeric Nanoparticles for Drug Delivery

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Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles

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Polymeric Nanostructures for Imaging and Therapy

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Therapeutic strategies to combat antibiotic resistance

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Anti-bacterial activity of graphene oxide as a new weapon nanomaterial to combat multidrug-resistance bacteria

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Nanotechnology as a Novel Approach in Combating Microbes Providing an Alternative to Antibiotics

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Inhaled formulations and pulmonary drug delivery systems for respiratory infections

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Pharmacokinetics of nanoparticles: current knowledge, future directions and its implications in drug delivery

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Pulmonary drug delivery systems for tuberculosis treatment

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Mesoporous silica nanoparticles for pulmonary drug delivery

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Pharmaceutical strategies to extend pulmonary exposure of inhaled medicines

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Pulmonary drug delivery by powder aerosols

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Polymeric micelles in mucosal drug delivery: challenges towards clinical translation

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Synthesized zinc peroxide nanoparticles (ZnO2-NPs): a novel antimicrobial, anti-elastase, anti-keratinase, and anti-inflammatory approach toward polymicrobial burn wounds

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Nanoparticle-Based Vaccine Delivery for Cancer Immunotherapy

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Potential Candidates of Natural Antioxidants From Herbs for Treating Lung Disorders: Focus on Redox Balance and Natural Products

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Recent advances in inhalable liposomes for treatment of pulmonary diseases: Concept to clinical stance

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The formulation of nanomedicines for treating tuberculosis

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Medical applications and prospects of polylactic acid materials

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Respirable nanocarriers as a promising strategy for antitubercular drug delivery

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Nanomaterials as Delivery Vehicles and Components of New Strategies to Combat Bacterial Infections: Advantages and Limitations

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Crosslinked-polyvinyl alcohol-carboxymethyl cellulose/ZnO nanocomposite fibrous mats containing erythromycin (PVA-CMC/ZnO-EM): Fabrication, characterization and in-vitro release and anti-bacterial properties

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Nanoparticle-mediated pulmonary drug delivery: state of the art towards efficient treatment of recalcitrant respiratory tract bacterial infections

Huang, Z., Kłodzińska, S. N., Wan, F., & Nielsen, H. M. (2021) · Drug Delivery and Translational Research · doi:10.1007/s13346-021-00954-1 · Cited by 113

On-demand storage and release of antimicrobial peptides using Pandora's box-like nanotubes gated with a bacterial infection-responsive polymer

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Development of a Multifunctional Platform Based on Strong, Intrinsically Photoluminescent and Antimicrobial Silica‐Poly(citrates)‐Based Hybrid Biodegradable Elastomers for Bone Regeneration

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The Potential of Antibiotics and Nanomaterial Combinations as Therapeutic Strategies in the Management of Multidrug-Resistant Infections: A Review

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Photothermal-Induced Antibacterial Activity of Gold Nanorods Loaded into Polymeric Hydrogel against Pseudomonas aeruginosa Biofilm

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Mechanisms and challenges of nanocarriers as non-viral vectors of therapeutic genes for enhanced pulmonary delivery

Wang, H., Lu, Q., Zhang, X., Guan, J., & Mao, S. (2022) · Journal of Controlled Release · doi:10.1016/j.jconrel.2022.10.061 · Cited by 90

Pulmonary drug delivery: a review on nanocarriers for antibacterial chemotherapy

Moreno-Sastre, M., Pastor, M., Salomon, C. J., Esquisabel, A., & Pedraz, J. L. (2015) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkv192 · Cited by 84

Inhaled anti-infective chemotherapy for respiratory tract infections: Successes, challenges and the road ahead

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Pulmonary delivery of tobramycin-loaded nanostructured lipid carriers for Pseudomonas aeruginosa infections associated with cystic fibrosis

Moreno-Sastre, M., Pastor, M., Esquisabel, A., Sans, E., Viñas, M., Fleischer, A., Palomino, E., Bachiller, D., & Pedraz, J. L. (2015) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2015.12.028 · Cited by 84

Emerging delivery approaches for targeted pulmonary fibrosis treatment

Diwan, R., Bhatt, H., Beaven, E., & Nurunnabi, M. (2023) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2023.115147 · Cited by 81

Inhalable PEGylated Phospholipid Nanocarriers and PEGylated Therapeutics for Respiratory Delivery as Aerosolized Colloidal Dispersions and Dry Powder Inhalers

Muralidharan, P., Mallory, E. K., Malapit, M., Hayes, D., & Mansour, H. M. (2014) · Pharmaceutics · doi:10.3390/pharmaceutics6020333 · Cited by 76

Exploiting solid lipid nanoparticles and nanostructured lipid carriers for drug delivery against cutaneous fungal infections

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Molecular and cellular cues governing nanomaterial–mucosae interactions: from nanomedicine to nanotoxicology

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Cyclic Peptide–Selenium Nanoparticles as Drug Transporters

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Nanoparticles: Antimicrobial Applications and Its Prospects

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Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis

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Sodium colistimethate loaded lipid nanocarriers for the treatment of Pseudomonas aeruginosa infections associated with cystic fibrosis

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How can nanoparticles contribute to antituberculosis therapy?

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Nanoincorporation of curcumin in polymer-glycerosomes and evaluation of their in vitro–in vivo suitability as pulmonary delivery systems

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Safety Assessment of Nanomaterials for Antimicrobial Applications

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Human immunity in vitro — Solving immunogenicity and more

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Metal-based nanoparticles for combating antibiotic resistance

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Inhalable polymer-glycerosomes as safe and effective carriers for rifampicin delivery to the lungs

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Extraction of essential oil from Dracocephalum kotschyi Boiss. (Lamiaceae), identification of two active compounds and evaluation of the antimicrobial properties

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Emerging aerosol drug delivery strategies: From bench to clinic

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Nanomedicines in the future of pediatric therapy.

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Inhaled antibiotic-loaded polymeric nanoparticles for the management of lower respiratory tract infections

Sabuj, M. Z. R., & Islam, N. (2021) · Nanoscale Advances · doi:10.1039/d1na00205h · Cited by 56

Biological assessment of self-assembled polymeric micelles for pulmonary administration of insulin

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Delivery of genome-editing biomacromolecules for treatment of lung genetic disorders

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Dealing with MDR bacteria and biofilm in the post-antibiotic era: Application of antimicrobial peptides-based nano-formulation

Song, X., Liu, P., Liu, X., Wang, Y., Wei, H., Zhang, J., Yu, L., Yan, X., & He, Z. (2021) · Materials Science and Engineering C · doi:10.1016/j.msec.2021.112318 · Cited by 59

A mechanistic perspective on targeting bacterial drug resistance with nanoparticles

Khorsandi, K., Keyvani‐Ghamsari, S., Shahidi, F. K., Hosseinzadeh, R., & Kanwal, S. (2021) · Journal of drug targeting · doi:10.1080/1061186x.2021.1895818 · Cited by 56

Formulation and evaluation of chitosan/polyethylene oxide nanofibers loaded with metronidazole for local infections

Zupančič, Š., Potrč, T., Baumgartner, S., Kocbek, P., & Kristl, J. (2016) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2016.10.030 · Cited by 52

Antibiotic resistance and nanotechnology: A narrative review

Zhu, X., Tang, Q., Zhou, X., & Momeni, M. R. (2024) · Microbial Pathogenesis · doi:10.1016/j.micpath.2024.106741 · Cited by 52

Liposomal remdesivir inhalation solution for targeted lung delivery as a novel therapeutic approach for COVID-19

Li, J., Zhang, K., Wu, D., Ren, L., Chu, X., Qin, C., Han, X., Hang, T., Xu, Y., Yang, L., et al. (2021) · Asian Journal of Pharmaceutical Sciences · doi:10.1016/j.ajps.2021.09.002 · Cited by 48

Mycoplasmas as Host Pantropic and Specific Pathogens: Clinical Implications, Gene Transfer, Virulence Factors, and Future Perspectives

Dawood, A. S., Algharib, S. A., Zhao, G., Zhu, T., Qi, M., Delai, K., Hao, Z., Marawan, M. A., Shirani, I., & Guo, A. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.855731 · Cited by 48

Biodegradation of the ZnO:Eu nanoparticles in the tissues of adult mouse after alimentary application

Kiełbik, P., Kaszewski, J., Rosowska, J., Wolska, E., Witkowski, B. S., Gralak, M. A., Gajewski, Z., Godlewski, M., & Godlewski, M. M. (2016) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2016.11.002 · Cited by 48

Bridging the Knowledge of Different Worlds to Understand the Big Picture of Cancer Nanomedicines

Balasubramanian, V., Liu, Z., Hirvonen, J. J., & Santos, H. A. (2017) · Advanced Healthcare Materials · doi:10.1002/adhm.201700432 · Cited by 48

New antituberculous drugs derived from natural products: current perspectives and issues in antituberculous drug development

Igarashi, M., Ishizaki, Y., & Takahashi, Y. (2017) · The Journal of Antibiotics · doi:10.1038/ja.2017.126 · Cited by 46

Alginate-pluronic topical gels loaded with thymol, norfloxacin and ZnO nanoparticles as potential wound dressings

Buyana, B., Aderibigbe, B. A., Ndinteh, D. T., Fonkui, T. Y., & Kumar, P. (2020) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2020.101960 · Cited by 47

Solubility and Dissolution Enhancement of Tadalafil Using Self-Nanoemulsifying Drug Delivery System

El‐Badry, M., Haq, N., Fetih, G. N., & Shakeel, F. (2014) · Journal of Oleo Science · doi:10.5650/jos.ess13236 · Cited by 45

The suppression of metastatic lung cancer by pulmonary administration of polymer nanoparticles for co-delivery of doxorubicin and Survivin siRNA

Xu, C., Tian, H., Wang, P., Wang, Y., & Chen, X. (2016) · Biomaterials Science · doi:10.1039/c6bm00601a · Cited by 45

Nanostructures for drug delivery in respiratory diseases therapeutics: Revision of current trends and its comparative analysis

Ibarra-Sánchez, L. Á., Gámez-Méndez, A. M., Martínez-Ruiz, M., Nájera-Martínez, E. F., Morales-Flores, B., Melchor-Martínez, E. M., Sosa‐Hernández, J. E., Parra‐Saldívar, R., & Iqbal, H. M. N. (2022) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2022.103219 · Cited by 45

Nanomaterials in the Prevention, Diagnosis, and Treatment of Mycobacterium Tuberculosis Infections

Xu, K., Liang, Z. C., Ding, X., Hu, H., Liu, S., Nurmik, M., Bi, S., Hu, F.-S., Ji, Z., Ren, J., et al. (2017) · Advanced Healthcare Materials · doi:10.1002/adhm.201700509 · Cited by 44

Nanoparticle-Mediated Strategies for Enhanced Drug Penetration and Retention in the Airway Mucosa

Yan, X., & Sha, X. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15102457 · Cited by 43

Oral pentamidine-loaded poly(d,l-lactic-co-glycolic) acid nanoparticles: an alternative approach for leishmaniasis treatment

Valle, I. V., Machado, M. E., Araújo, C. D. C. B., Cunha‐Júnior, E. F., Pacheco, J. D. S., Torres-Santos, E. C., da Silva, L. C. R. P., Cabral, L. M., do Carmo, F. A., & Sathler, P. C. (2019) · Nanotechnology · doi:10.1088/1361-6528/ab373e · Cited by 43

Production of Drug-Loaded Polymeric Nanoparticles by Electrospraying Technology

Sosnik, A. (2014) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2014.1887 · Cited by 42

Pulmonary Delivery of Emerging Antibacterials for Bacterial Lung Infections Treatment

Li, J., Zheng, H., & Leung, S. S. Y. (2022) · Pharmaceutical Research · doi:10.1007/s11095-022-03379-8 · Cited by 41

Efficient EFGR mediated siRNA delivery to breast cancer cells by Cetuximab functionalized Pluronic® F127/Gelatin

Rafael, D. F. D. S., Martínez-Trucharte, F., Andrade, F., Seras‐Franzoso, J., García‐Aranda, N., Gener, P., Sayós, J., Arango, D., Abasolo, I., & Schwartz, S. (2017) · Chemical Engineering Journal · doi:10.1016/j.cej.2017.12.114 · Cited by 40

AKT2 siRNA delivery with amphiphilic-based polymeric micelles show efficacy against cancer stem cells

Rafael, D. F. D. S., Gener, P., Andrade, F., Seras‐Franzoso, J., Montero, S., Fernández, Y., Hidalgo, M. M., Arango, D., Sayós, J., Florindo, H. F., et al. (2018) · Drug Delivery · doi:10.1080/10717544.2018.1461276 · Cited by 41

Therapeutic Efficacy of Novel Antimicrobial Peptide AA139-Nanomedicines in a Multidrug-Resistant Klebsiella pneumoniae Pneumonia-Septicemia Model in Rats

van der Weide, H., Cossío, U., Gracia, R., Welscher, Y. M. T., ten Kate, M. T., van der Meijden, A., Marradi, M., Ritsema, J. A. S., Jongh, D. M. C. V.-D., Storm, G., et al. (2020) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00517-20 · Cited by 40

A Review on Micro and Nanoengineering in Powder-Based Pulmonary Drug Delivery

Pasero, L., Susa, F., Limongi, T., & Pisano, R. (2024) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2024.124248 · Cited by 39

Optimization of a dry powder inhaler of ciprofloxacin-loaded polymeric nanomicelles by spray drying process

Farhangi, M. A., Mahboubi, A., Kobarfard, F., Vatanara, A., & Mortazavi, S. A. (2018) · Pharmaceutical Development and Technology · doi:10.1080/10837450.2018.1545237 · Cited by 39

Nanoparticle-Based Devices in the Control of Antibiotic Resistant Bacteria

Gómez-Núñez, M. F., Castillo-López, M., Sevilla-Castillo, F., Roque-Reyes, O. J., Romero-Lechuga, F., Medina-Santos, D., Daniel, R., & Peón, A. N. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.563821 · Cited by 41

Long-acting vaccine delivery systems

Walvekar, P., Kumar, P., & Choonara, Y. E. (2023) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2023.114897 · Cited by 39

Nanomedicinal strategies as efficient therapeutic interventions for delivery of cancer vaccines

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