The DOI matches its Crossref record; 214 of the 214 references it cites were found in a registry or an index.
Nanocarriers for delivery of platinum anticancer drugs
Open accessAbstract
Platinum based anticancer drugs have revolutionized cancer chemotherapy, and continue to be in widespread clinical use especially for management of tumors of the ovary, testes, and the head and neck. However, several dose limiting toxicities associated with platinum drug use, partial anti-tumor response in most patients, development of drug resistance, tumor relapse, and many other challenges have severely limited the patient quality of life. These limitations have motivated an extensive research effort towards development of new strategies for improving platinum therapy. Nanocarrier-based delivery of platinum compounds is one such area of intense research effort beginning to provide encouraging preclinical and clinical results and may allow the development of the next generation of platinum chemotherapy. This review highlights current understanding on the pharmacology and limitations of platinum compounds in clinical use, and provides a comprehensive analysis of various platinum–polymer complexes, micelles, dendrimers, liposomes and other nanoparticles currently under investigation for delivery of platinum drugs.
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Cites
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Metadata
- Authors
- Oberoi, H. S., Nukolova, N. V., Kabanov, A. V., & Bronich, T. K.
- Venue
- Advanced Drug Delivery Reviews
- Publisher
- Elsevier BV
- Published
- 2013-11
- Volume
- 65
- Issue
- 13-14
- Pages
- 1667-1685
- ISSN
- 0169-409X (ISSN-L)
- OpenAlex
- W2091945030
- Cited by
- 396
- References
- 214
- FWCI
- 2.33
- Type
- journal article
- Language
- en
- Open access
- green
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- Oberoi, H. S., Nukolova, N. V., Kabanov, A. V., & Bronich, T. K. (2013). Nanocarriers for delivery of platinum anticancer drugs. Advanced Drug Delivery Reviews. https://doi.org/10.1016/j.addr.2013.09.014
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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