The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Polysaccharide-based nanoparticles for theranostic nanomedicine
Open accessAbstract
Polysaccharides are natural biological molecules that have numerous advantages for theranostics, the integrated approach of therapeutics and diagnostics. Their derivable reactive groups can be leveraged for functionalization with a nanoparticle-enabling conjugate, therapeutics (small molecules, proteins, peptides, photosensitizers) and/or diagnostic agents (imaging agents, sensors). In addition, polysaccharides are diverse in size and charge, biodegradable and abundant and show low toxicity in vivo. Polysaccharide-based nanoparticles are increasingly being used as platforms for simultaneous drug delivery and imaging and are therefore becoming popular theranostic nanoparticles. The review focuses on the method of nanoparticle formation (self-assembled, physical or chemical cross-linked) when engineering polysaccharide-based nanoparticles for theranostic nanomedicine. We highlight recent examples of polysaccharides-based theranostic systems from literature and their potential for use in the clinic, particularly chitosan- and hyaluronic acid-based NPs.
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Cites
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Self-citationInhalable alginate nanoparticles as antitubercular drug carriers against experimental tuberculosis
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Cited by
An Overview of Chitosan Nanoparticles and Its Application in Non-Parenteral Drug Delivery
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Review of the efficacy of nanoparticle-based drug delivery systems for cancer treatment
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Development and application of hyaluronic acid in tumor targeting drug delivery
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Polysaccharide nanoparticles: from fabrication to applications
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Metadata
- Authors
- Swierczewska, M., Han, H. S., Kim, K., Park, J. H., & Lee, S.
- Venue
- Advanced Drug Delivery Reviews
- Publisher
- Elsevier BV
- Published
- 2016-04
- Volume
- 99
- Issue
- Pt A
- Pages
- 70-84
- ISSN
- 0169-409X (ISSN-L)
- OpenAlex
- W2177205490
- Cited by
- 415
- References
- 8
- FWCI
- 1.03
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
