The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
ASCEND: A Study of Cardiovascular Events iN Diabetes: Characteristics of a randomized trial of aspirin and of omega-3 fatty acid supplementation in 15,480 people with diabetes
Open accessAbstract
OBJECTIVES: The use of aspirin for the secondary prevention of cardiovascular disease (CVD) is firmly established, and the proportional reductions in heart attacks and strokes appear to be similar in people with and without diabetes. Uncertainty remains about the role of antiplatelet treatments for primary prevention of CVD, and guidelines vary in their recommendations. It has also been hypothesized that long-term aspirin can prevent gastro-intestinal and other cancers. Observational studies suggest associations between higher intakes of omega-3 fatty acids (FA) and lower rates of CVD, but there is no large-scale randomized evidence to support using prophylactic omega-3 FA supplementation in primary prevention. ASCEND is a randomized trial assessing whether 100 mg daily aspirin safely prevents CVD and cancer in patients with diabetes without known arterial disease. It is also assessing whether supplementation with 1 g omega-3 FA daily prevents CVD. This paper describes the methods and baseline characteristics of the randomized participants. METHODS AND RESULTS: Between 2005 and 2011, using mail-based methods, 15,480 people with diabetes were randomized to aspirin versus placebo and, in a factorial design, to omega-3 FA supplementation versus placebo. Blood and urine samples were collected to allow baseline stratification by biochemical prognostic variables (e.g. HbA1c, blood lipids). Follow-up is for a median of at least 7 years. CONCLUSIONS: Demonstrating that prophylactic aspirin safely reduces the risk of CVD or cancer in the primary prevention setting, or that omega-3 FA supplementation prevents CVD, would be relevant to hundreds of millions of people worldwide who are currently not receiving such therapies. The results of ASCEND will be reported in 2018.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Figures
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“The data analysis plan was finalized by the steering committee and was published 16 while all the members were still unaware of the trial results according to group assignment (except for the statistician, who was aware of these assignments and who was not involved in development of the data analysis plan).”
From Effects of aspirin for primary prevention in persons with diabetes mellitus (2018) · cites this paper as [16]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Similarly, both the ASCEND trial [90], conducted in 15,480 diabetic patients without known cardiovascular disease, and the VITAL study [91], which included > 25,000 healthy individuals, failed to show significant reductions in major cardiovascular events with EPA + DHA supplementation.”
From Targeting triglycerides for cardiovascular risk reduction (2026) · cites this paper as [90]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Diagnosis and Classification of Diabetes Mellitus
American Diabetes Association (2010) · Diabetes Care · doi:10.2337/dc11-s062 · Cited by 14,094
European Guidelines on cardiovascular disease prevention in clinical practice (version 2012)
Authors/Task Force Members:, Perk, J., De Backer, G., Gohlke, H., Graham, I., Reiner, Ž., Verschuren, M., Albus, C., Benlian, P., Boysen, G., et al. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehs092 · Cited by 8,490
Collaboration, A. T. (2002) · BMJ · doi:10.1136/bmj.324.7329.71 · Cited by 6,943
2016 European Guidelines on cardiovascular disease prevention in clinical practice
Piepoli, M. F., Hoes, A. W., Agewall, S., Albus, C., Brotons, C., Catapano, A. L., Cooney, M.-T., Corrà, U., Cosyns, B., Deaton, C., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw106 · Cited by 6,457
Diagnosis and classification of diabetes mellitus
American Diabetes Association (2010) · Diabetes Care · doi:10.2337/dc10-s062 · Cited by 5,491
The Emerging Risk Factors Collaboration (2010) · The Lancet · doi:10.1016/s0140-6736(10)60484-9 · Cited by 5,125
Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease
Kris-Etherton, P. M., Harris, W. S., & Appel, L. J. (2002) · Circulation · doi:10.1161/01.cir.0000038493.65177.94 · Cited by 3,707
Burr, M. L., Gilbert, J. F., Holliday, R. M., Elwood, P. C., Fehily, A. M., Rogers, S., Sweetnam, P. M., & Deadman, N. M. (1989) · The Lancet · doi:10.1016/s0140-6736(89)90828-3 · Cited by 2,610
Research works printed but not linked: 1
- 1998, Heart, 80, S1
Cited by
Sorted by citations
KDIGO 2024 clinical practice guideline for the evaluation and management of chronic kidney disease
Stevens, P. E., Ahmed, S. B., Carrero, J. J., Foster, B., Francis, A., Hall, R. K., Herrington, W. G., Hill, G., Inker, L. A., Kazancıoğlu, R., et al. (2024) · Kidney International · doi:10.1016/j.kint.2023.10.018 · Cited by 8,530
Cosentino, F., Grant, P. J., Aboyans, V., Bailey, C. J., Ceriello, A., Delgado, V., Federici, M., Filippatos, G., Grobbee, D. E., Hansen, T. B., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehz486 · Cited by 4,763
Effects of aspirin for primary prevention in persons with diabetes mellitus
The ASCEND Study Collaborative Group (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1804988 · Cited by 1,200
Effects of n−3 Fatty Acid Supplements in Diabetes Mellitus
The ASCEND Study Collaborative Group (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1804989 · Cited by 698
Chow, J. H., Khanna, A. K., Kethireddy, S., Yamane, D. P., Levine, A. R., Jackson, A. M., McCurdy, M. T., Tabatabai, A., Kumar, G., Park, P., et al. (2020) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000005292 · Cited by 316
Ten things to know about ten cardiovascular disease risk factors
Bays, H. E., Taub, P. R., Epstein, E., Michos, E. D., Ferraro, R. A., Bailey, A. L., Kelli, H. M., Ferdinand, K. C., Echols, M. R., Weintraub, H., et al. (2021) · American Journal of Preventive Cardiology · doi:10.1016/j.ajpc.2021.100149 · Cited by 274
Coronary heart disease risk: Low-density lipoprotein and beyond
Shaya, G. E., Leucker, T. M., Jones, S. R., Martin, S. S., & Toth, P. P. (2021) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2021.04.002 · Cited by 247
Aspirin-free strategies in cardiovascular disease and cardioembolic stroke prevention
Capodanno, D., Mehran, R., Valgimigli, M., Baber, U., Windecker, S., Vranckx, P., Dangas, G., Rollini, F., Kimura, T., Collet, J., et al. (2018) · Nature Reviews Cardiology · doi:10.1038/s41569-018-0049-1 · Cited by 220
Abraham, N. S., Barkun, A. N., Sauer, B. G., Douketis, J. D., Laine, L., Noseworthy, P. A., Telford, J. J., & Leontiadis, G. I. (2022) · The American Journal of Gastroenterology · doi:10.14309/ajg.0000000000001627 · Cited by 190
Nicholls, S. J., Lincoff, A. M., Bash, D., Ballantyne, C. M., Barter, P. J., Davidson, M. H., Kastelein, J. J. P., Koenig, W., McGuire, D. K., Mozaffarian, D., et al. (2018) · Clinical Cardiology · doi:10.1002/clc.23055 · Cited by 167
Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer
Guirguis‐Blake, J., Evans, C. V., Perdue, L. A., Bean, S., & Senger, C. A. (2022) · JAMA · doi:10.1001/jama.2022.3337 · Cited by 169
Ten things to know about ten cardiovascular disease risk factors – 2022
Bays, H. E., Agarwala, A., German, C. A., Satish, P., Iluyomade, A., Dudum, R., Thakkar, A., Rifai, M. A., Mehta, A., Thobani, A., et al. (2022) · American Journal of Preventive Cardiology · doi:10.1016/j.ajpc.2022.100342 · Cited by 148
Real-world studies no substitute for RCTs in establishing efficacy
Gerstein, H. C., McMurray, J., & Holman, R. R. (2019) · The Lancet · doi:10.1016/s0140-6736(18)32840-x · Cited by 97
A systematic review of methods used to conduct decentralised clinical trials
Rogers, A., Paoli, G. D., Subbarayan, S., Copland, R. R., Harwood, K. E., Coyle, J., Mitchell, L., MacDonald, T. M., & Mackenzie, I. S. (2021) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.15205 · Cited by 96
Berk, M., Woods, R. L., Nelson, M. R., Shah, R. C., Reid, C. M., Storey, E., Fitzgerald, S., Lockery, J. E., Wolfe, R., Mohebbi, M., et al. (2020) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2020.1214 · Cited by 89
Omega-3 Fatty Acids in Cardiovascular Disease and Diabetes: a Review of Recent Evidence
Bhat, S. Z., Sarkar, S., Zaffar, D., Dandona, P., & Kalyani, R. R. (2023) · Current Cardiology Reports · doi:10.1007/s11886-022-01831-0 · Cited by 51
Abraham, N. S., Barkun, A. N., Sauer, B. G., Douketis, J. D., Laine, L., Noseworthy, P. A., Telford, J. J., & Leontiadis, G. I. (2022) · Journal of the Canadian Association of Gastroenterology · doi:10.1093/jcag/gwac010 · Cited by 45
Effects of aspirin on dementia and cognitive function in diabetic patients: the ASCEND trial
Parish, S., Mafham, M., Offer, A., Barton, J., Wallendszus, K., Stevens, W., Buck, G., Haynes, R., Collins, R., Bowman, L., et al. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehac179 · Cited by 40
Self-citationGulizia, M. M., Colivicchi, F., Abrignani, M. G., Ambrosetti, M., Aspromonte, N., Barile, G., Caporale, R., Casolo, G., Chiuini, E., Lenarda, A. D., et al. (2018) · European Heart Journal Supplements · doi:10.1093/eurheartj/suy019 · Cited by 38
Understanding the use of observational and randomized data in cardiovascular medicine
Bowman, L. J., Baras, A., Bombien, R. H., Califf, R. M., Chen, Z., Gale, C. P., Gaziano, J. M., Grobbee, D. E., Maggioni, A. P., Muse, E. D., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehaa020 · Cited by 38
Self-citationHarper, C., Mafham, M. M., Herrington, W. G., Staplin, N., Stevens, W., Wallendszus, K., Haynes, R., Landray, M., Parish, S., Bowman, L. J., et al. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.39748 · Cited by 34
Self-citationThe TICONC (Ticagrelor-Oncology) Study
Wright, J. R., Chauhan, M., Shah, C., Ring, A. E., Thomas, A., Goodall, A. H., & Adlam, D. (2020) · JACC CardioOncology · doi:10.1016/j.jaccao.2020.04.009 · Cited by 33
Aldoori, J., Cockbain, A. J., Toogood, G. J., & Hull, M. A. (2022) · Gut · doi:10.1136/gutjnl-2021-326362 · Cited by 33
Maki, K. C., & Dicklin, M. R. (2018) · Nutrients · doi:10.3390/nu10070864 · Cited by 26
Gallagher, H., Dumbleton, J., Maishman, T., Whitehead, A. L., Moore, M. V., Fuat, A., Fitzmaurice, D. A., Henderson, R. A., Lord, J. L., Griffith, K. E., et al. (2022) · Trials · doi:10.1186/s13063-022-06132-z · Cited by 25
Thromboxane biosynthesis and future events in diabetes: the ASCEND trial
Petrucci, G., Buck, G. A. N., Rocca, B., Parish, S., Baigent, C., Hatem, D., Mafham, M. M., Habib, A., Bowman, L. J., Armitage, J., et al. (2024) · European Heart Journal · doi:10.1093/eurheartj/ehad868 · Cited by 28
Self-citationLewis, E., Steenson, S., Haslam, R. P., McDonald, E., Sharman, M., Τράκα, Μ., Stanton, A. V., Napier, J. A., Sweeting, A., Saleh, R. N. M., et al. (2025) · Nutrition Research Reviews · doi:10.1017/s0954422425100127 · Cited by 30
Kidney disease trials for the 21st century: innovations in design and conduct
Herrington, W. G., Staplin, N., & Haynes, R. (2019) · Nature Reviews Nephrology · doi:10.1038/s41581-019-0212-x · Cited by 25
Self-citationKeng, M. J., Leal, J., Mafham, M. M., Bowman, L. J., Armitage, J., & Mihaylova, B. (2021) · Value in Health · doi:10.1016/j.jval.2021.09.005 · Cited by 24
Self-citationDecrements in health‐related quality of life associated with adverse events in people with diabetes
Keng, M. J., Leal, J., Bowman, L. J., Armitage, J., Mihaylova, B., & ASCEND Study Collaborative Group (2021) · Diabetes Obesity and Metabolism · doi:10.1111/dom.14610 · Cited by 25
Self-citationExploring the therapeutic potential of omega-3 fatty acids in depression
Sikka, P., Behl, T., Sharma, S., Sehgal, A., Bhatia, S., Al‐Harrasi, A., Singh, S., Sharma, N., & Aleya, L. (2021) · Environmental Science and Pollution Research · doi:10.1007/s11356-021-14884-5 · Cited by 22
Huseynov, A., Reinhardt, J., Chandra, L., Dürschmied, D., & Langer, H. F. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076280 · Cited by 24
Diabetes Care Editors’ Expert Forum 2018: Managing Big Data for Diabetes Research and Care
Riddle, M. C., Blonde, L., Gerstein, H. C., Gregg, E. W., Holman, R. R., Lachin, J. M., Nichols, G. A., Turchin, A., & Cefalu, W. T. (2019) · Diabetes Care · doi:10.2337/dci19-0020 · Cited by 21
Rijjal, D. A., Liu, Y., Lai, M., Song, Y., Danaei, Z., Wu, A., Mohan, H., Li, W., Schopfer, F. J., Dai, F. F., et al. (2021) · iScience · doi:10.1016/j.isci.2021.102909 · Cited by 19
Gill, R., Al‐Badr, M., Al-Ghouti, M. A., Mohamed, N. A., Abou-Saleh, H., & Rahman, M. M. (2024) · Marine Drugs · doi:10.3390/md22060256 · Cited by 19
Diabetes and cardiovascular disease in older adults
Bilal, A., & Pratley, R. E. (2024) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.15259 · Cited by 18
Hull, M. A., Sprange, K., Hepburn, T., Tan, W., Shafayat, A., Rees, C. J., Clifford, G. M., Logan, R. F., Loadman, P. M., Williams, E. A., et al. (2019) · Efficacy and Mechanism Evaluation · doi:10.3310/eme06040 · Cited by 17
N-3 polyunsaturated fatty acids for cardiovascular risk
Goff, Z. D., & Nissen, S. E. (2022) · Current Opinion in Cardiology · doi:10.1097/hco.0000000000000962 · Cited by 17
Triglycerides and Cardiovascular Outcomes—Can We REDUCE-IT ?
Pradhan, A. K., Bhandari, M., Vishwakarma, P., & Sethi, R. (2020) · International Journal of Angiology · doi:10.1055/s-0040-1701639 · Cited by 18
Laferrière, C., Moazzami, C., Belley‐Côté, E. P., Bainey, K. R., Marquis‐Gravel, G., Fama, A., Lordkipanidzé, M., & Potter, B. J. (2023) · CJC Open · doi:10.1016/j.cjco.2023.08.011 · Cited by 19
González‐Juanatey, C., Anguita-Sánchez, M. P., Barrios, V., Nuñez-Gil, I. J., Gómez-Doblas, J. J., García–Moll, X., Gormaz, C. L., Rollán-Gómez, M. J., Peral-Disdie, V., Martínez‐Dolz, L., et al. (2022) · PLoS ONE · doi:10.1371/journal.pone.0263277 · Cited by 16
Lima, M. R., Lopes, P. M., & Ferreira, A. M. (2024) · Therapeutic Advances in Cardiovascular Disease · doi:10.1177/17539447241249650 · Cited by 19
Sammons, E. L., Buck, G. A. N., Bowman, L. J., Stevens, W. M., Hammami, I., Parish, S., Armitage, J., Sammons, E. L., Bowman, L. J., Stevens, W., et al. (2023) · Ophthalmology · doi:10.1016/j.ophtha.2023.11.030 · Cited by 16
Self-citationMogul, A., Leppien, E. E., Laughlin, E., & Spinler, S. A. (2020) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2020.1817389 · Cited by 15
Springer, S. P., Mor, M. K., Sileanu, F. E., Zhao, X., Aspinall, S. L., Ersek, M. T., Niznik, J. D., Hanlon, J. T., Hunnicutt, J. N., Gellad, W. F., et al. (2020) · Journal of the American Geriatrics Society · doi:10.1111/jgs.16346 · Cited by 15
Ganda, O. P. (2020) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000694 · Cited by 11
Liu, X., Gong, M., & Wu, N. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1503704 · Cited by 11
Aspirin for Primary Stroke Prevention; Evidence for a Differential Effect in Men and Women
Gdovinová, Z., Kremer, C., Lorenzano, S., Dawson, J., Lal, A., & Caso, V. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.856239 · Cited by 13
Approach to Lipid Management in the Patient With Diabetes
Kim, S. J., & Subramanian, S. (2025) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaf018 · Cited by 12
Hospital costs associated with adverse events in people with diabetes in the UK
Keng, M. J., Leal, J., Bowman, L. J., Armitage, J., Mihaylova, B., & ASCEND Study Collaborative Group (2022) · Diabetes Obesity and Metabolism · doi:10.1111/dom.14796 · Cited by 9
Self-citationPolyunsaturated Fatty Acids: Impact on Health and Disease Status
Akbar, S., Bhatti, M. Z., Saeed, R. F., & Qazi, A. S. (2021) · Life and Science · doi:10.37185/lns.1.1.85 · Cited by 8
Kayani, T., Ahmad, B., Chang, R., Qian, F., Sahinoz, M., Rehan, M., Giaimo, A., Spatz, E. S., & Hu, J. (2024) · Pharmacoepidemiology · doi:10.3390/pharma3010009 · Cited by 9
Role of Aspirin for Primary Prevention in Persons with Diabetes Mellitus and in the Elderly
Patel, N., & Baliga, R. R. (2020) · Current Cardiology Reports · doi:10.1007/s11886-020-01296-z · Cited by 7
Sammons, E. L., Bowman, L. J., Stevens, W., Buck, G. A. N., Wallendszus, K., Hammami, I., Parish, S., & Armitage, J. (2023) · Contemporary Clinical Trials Communications · doi:10.1016/j.conctc.2023.101184 · Cited by 8
Self-citationChandra, A., Røsjø, H. R., Eide, I. A., Vigen, T., Ihle‐Hansen, H., Orstad, E. B., Rønning, O. M., Lyngbakken, M. N., Berge, T., Schmidt, E. B., et al. (2019) · European Journal of Nutrition · doi:10.1007/s00394-019-02007-3 · Cited by 8
Current Understanding of Diabetic Dyslipidemia: A Review
Gupta, A., & Gupta, R. (2022) · Journal of the Indian Institute of Science · doi:10.1007/s41745-022-00346-5 · Cited by 6
Harper, C., Mafham, M. M., Herrington, W. G., Staplin, N., Stevens, W., Wallendszus, K., Haynes, R., Landray, M., Parish, S., Bowman, L. J., et al. (2023) · Heart · doi:10.1136/heartjnl-2023-322616 · Cited by 7
Self-citationSammons, E. L., Buck, G. A. N., Bowman, L. J., Stevens, W. M., Hammami, I., Parish, S., Armitage, J., Sammons, E., Bowman, L., Stevens, W., et al. (2024) · Ophthalmology · doi:10.1016/j.ophtha.2024.01.018 · Cited by 8
Self-citationStreamlined mail-based methods for large randomised trials: lessons learnt from the ASCEND study
Mafham, M. M., Bowman, L. J., Haynes, R., & Armitage, J. (2019) · Diabetologia · doi:10.1007/s00125-019-05049-8 · Cited by 6
Self-citationAmedei, A., Lamminpää, I., & Parolini, C. (2025) · Biomedicines · doi:10.3390/biomedicines13102428 · Cited by 6
Mollace, R., Gliozzi, M., Macrì, R., Tavernese, A., Musolino, V., Carresi, C., Maiuolo, J., Muscoli, C., Tomino, C., Rosano, G., et al. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14010187 · Cited by 6
Cardiovascular Prevention: Migrating From a Binary to a Ternary Classification
Doneen, A. L., Bale, B. F., Vigerust, D. J., & Leimgruber, P. P. (2020) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2020.00092 · Cited by 5
McRae, M., & Wang, C. C. L. (2022) · Primary Care Clinics in Office Practice · doi:10.1016/j.pop.2021.11.012 · Cited by 7
Parish, S., Buck, G. A. N., Aung, T., Mafham, M. M., Clark, S. J., Hill, M., Collins, R., Bowman, L. J., Armitage, J., & on behalf of the ASCEND Study Collaborative Group (2023) · Trials · doi:10.1186/s13063-023-07198-z · Cited by 5
Self-citationde Jong, A. J., Zuidgeest, M. G. P., Santa‐Ana‐Téllez, Y., Hallgreen, C. E., van Sloten, T. T., de Boer, A., & Gardarsdóttir, H. (2025) · Drug Discovery Today · doi:10.1016/j.drudis.2025.104304 · Cited by 4
Tan, S. Y., Cronin, H., Byrne, S., O’Donovan, A., & Tuthill, A. (2021) · Irish Journal of Medical Science (1971 -) · doi:10.1007/s11845-021-02649-5 · Cited by 4
Aspirin in a diabetic retinopathy setting: Insights from NO BLIND study
Pafundi, P. C., Galiero, R., Caturano, A., Acierno, C., de Sio, C., Vetrano, E., Nevola, R., Gelso, A., Bono, V., Costagliola, C., et al. (2020) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2020.06.021 · Cited by 4
Wang, I. E., Yi, S., Block, R., & Mousa, S. A. (2021) · Nutrition Research Reviews · doi:10.1017/s0954422421000238 · Cited by 4
Kang, S. H., Lee, J., Kim, J. H., & Jang, A. Y. (2025) · Medicina · doi:10.3390/medicina61101730 · Cited by 4
Nouveaux outils d’évaluation du risque cardiovasculaire
Bauduceau, B., & Bordier, L. (2019) · Médecine des Maladies Métaboliques · doi:10.1016/s1957-2557(19)30020-3 · Cited by 3
Platelet Implication in Atherosclerosis Pathogenesis
Poznyak, A. V., Orekhova, V. A., Sukhorukov, V. N., Melnichenko, A. A., Pleshko, E. M., & Orekhov, A. N. (2024) · Journal of Angiotherapy · doi:10.25163/angiotherapy.819385 · Cited by 4
Effect of Low-Dose Aspirin on the Elderly
Darraj, A. (2024) · Cureus · doi:10.7759/cureus.54658 · Cited by 3
Emirates consensus recommendations on cardiovascular risk management in type 2 diabetes
Sabbour, H. M., Almahmeed, W. A., Alawadi, F., Shehab, A. M., Zubaidi, A. A., Bashier, A. M., Ghulam, A. R., Rashid, F., Zaky, H., Kassem, H. H., et al. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1395630 · Cited by 3
Funck, K. L., Borregaard, B., Egstrup, K., Fredslund, E. K., Hansen, T. W., Kallestrup, P., Olsen, M. H., Reventlow, S. D., Rossing, P. R., Sandbæk, A., et al. (2025) · BMJ Open · doi:10.1136/bmjopen-2025-106018 · Cited by 3
Paul, M., Song, W. J., & Im, J. (2026) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2026.126602 · Cited by 2
Anticoagulation and Antiplatelet Agents in Peripheral Arterial Interventions
Taylor, J., Stiepel, H. R., & Keefe, N. (2022) · Seminars in Interventional Radiology · doi:10.1055/s-0042-1757314 · Cited by 2
Antithrombotic therapy in patients with diabetes mellitus
Kryukov, E., Kuchmin, A., Umanskaya, E. P., Nagorny, M. B., Shevelev, A. A., & Rozhkova, A. (2023) · Bulletin of the Russian Military Medical Academy · doi:10.17816/brmma108793 · Cited by 2
Urinary thromboxane and risk of cardiovascular events: role of aspirin
Eikelboom, J. W., & Kruger, P. C. (2024) · European Heart Journal · doi:10.1093/eurheartj/ehae003 · Cited by 2
Sammons, E. L., Bowman, L. J., Stevens, W., Buck, G. A. N., Hammami, I., Parish, S., & Armitage, J. (2025) · BMJ Open · doi:10.1136/bmjopen-2024-090605 · Cited by 2
Self-citationCapodanno, D. (2018) · EuroIntervention · doi:10.4244/eijv14i11a207 · Cited by 2
Vasquez, A., & Pizzorno, J. E. (2019) · PubMed Central · Cited by 2
A Systematic Review of Methods used to Conduct Decentralised Clinical Trials
Rogers, A. (2022) · doi:10.26226/m.619bb9febe545488cfae505f · Cited by 2
Primärprävention der koronaren Herzkrankheit
Mühleck, F., & Laufs, U. (2019) · Herz · doi:10.1007/s00059-019-04873-3 · Cited by 1
Current Evidence and Future Directions of Omega-3 Supplementation and Cardiovascular Disease Risk
Dwiputra, B., Santoso, A., Purwowiyoto, B. S., Radi, B., Pandhita, B. A. W., Fatrin, S., & Ambari, A. M. (2023) · International Journal of Angiology · doi:10.1055/s-0043-1777258 · Cited by 3
2025 Egyptian guidelines for the management of dyslipidemia
Reda, A., Taha, H., Badran, H. M., Khamis, H., Kamal, S., Elserafy, A. S., Dawoud, M. H., Elamragy, A. A., Bendary, A., & Shaker, M. M. (2026) · The Egyptian Heart Journal · doi:10.1186/s43044-026-00716-9 · Cited by 1
Hammami, I., Mafham, M. M., Emberson, J., Offer, A. R., Hopewell, J. C., Armitage, J., Baigent, C., & Parish, S. (2025) · Heart · doi:10.1136/heartjnl-2024-324841 · Cited by 1
Self-citationMonitoring of Aspirin Therapy in Patients with Cerebrovascular Pathology
Tanashyan, M. M., Раскуражев, А. А., Корнилова, А. А., Шабалина, А. А., Абаимов, Д. А., & Naminov, A. V. (2021) · Rational Pharmacotherapy in Cardiology · doi:10.20996/1819-6446-2021-08-15 · Cited by 1
Targeting triglycerides for cardiovascular risk reduction
Maiorca, C., Tramontano, D., Di Costanzo, A., & D’Erasmo, L. (2026) · Internal and Emergency Medicine · doi:10.1007/s11739-026-04383-1
REDUCE-IT: Omega-3-Fettsäuren in der kardiovaskulären Primär- und Sekundärprävention
Müller, S. (2019) · Der Kardiologe · doi:10.1007/s12181-018-0296-8
Current status of cardiovascular disease prevention in diabetic foot patients
Ferreira, L., Pereira, T., Fonseca, L., Amado, A., & Carvalho, R. (2019) · Revista Portuguesa de Endocrinologia Diabetes e Metabolismo · doi:10.26497/ao180025
Gui, Q., Liang, X., Ge, Z. Z., Xiong, H., Zhu, Q., & Lü, H. (2020) · Research Square · doi:10.21203/rs.3.rs-37915/v1
Luna, J. A. G., López‐Medina, E., Maldonado-Vargas, N. D., & Smith, A. D. (2021) · Wellcome Open Research · doi:10.12688/wellcomeopenres.17036.1
ウエイトトレーニング時のウォーミングアップ(2)クイックリフト実施時の各種競技アスリートの実践例
槇野, 陽., 下嶽, 進., & 砂川, 力. (2008)
(2018) · Wiley eBooks · doi:10.1002/9781118829875.refs
Imaging Atherosclerosis for Risk Stratification
Agha, A. M., & Nambi, V. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-88286-6.00010-8
Comorbidies of Blood Pressure and Blood Glucose: Challenges and Future TrendsPreprint
Ashisha, G. R., Mary, X. A., Karthik, C., & Gheisari, M. (2024) · Preprints.org · doi:10.20944/preprints202403.1154.v1
Zając, A., Sroczyńska, K., & Miszczyk, J. U. (2024) · Current Issues in Pharmacy and Medical Sciences · doi:10.2478/cipms-2024-0010
Sammons, E. L., Buck, G. A. N., Bowman, L. J., Stevens, W. M., Hammami, I., Parish, S., Armitage, J., & on behalf of the ASCEND Study Collaborative Group (2024) · BMC Ophthalmology · doi:10.1186/s12886-024-03741-x
Self-citationHoellger, M., Kehrer, M., Wirtz, D. C., & Kohlhof, H. (2025) · Advances in Geriatric Medicine and Research · doi:10.20900/agmr20250004
Sammons, E. L., Bowman, L. J., Mafham, M. M., & Armitage, J. (2025) · Contemporary Clinical Trials Communications · doi:10.1016/j.conctc.2025.101474
Self-citation
Metadata
- Authors
- Bowman, L., Mafham, M., Stevens, W., Haynes, R., Aung, T., Chen, F., Buck, G., Collins, R., & Armitage, J.
- Affiliations
- University of Oxford (GB)
- Royal Berkshire Hospital (GB)
- Corresponding author
- Bowman, Louise
- ORCID
- Venue
- American Heart Journal
- Publisher
- Elsevier BV
- Published
- 2018-04
- Volume
- 198
- Pages
- 135-144
- ISSN
- 0002-8703 (ISSN-L)
- PMC
- PMC5971211
- OpenAlex
- W2779357131
- Cited by
- 106
- References
- 39
- Citations by year
- 2026: 5 · 2025: 13 · 2024: 14 · 2023: 11 · 2022: 16 · 2021: 13 · 2020: 13 · 2019: 12 · 2018: 8
- FWCI
- 6.98
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- American Heart Journal (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- National Institute for Health and Care Research
- British Heart Foundation (SP/08/010/25939, SP/14/3/31114)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Antiplatelet Therapy and Cardiovascular Diseases
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Health Sciences › Medicine › Pharmacology (medical) › Inflammatory mediators and NSAID effects
- Keywords
- aspirin, omega-3 fatty acids, diabetes mellitus, cardiovascular disease prevention, primary prevention, antiplatelet therapy, cancer prevention, gastrointestinal bleeding, factorial trial, baseline characteristics, HbA1c, serum lipids
- MeSH terms
- Aged, Aspirin, Cardiovascular Diseases, Diabetes Mellitus, Dose-Response Relationship, Drug, Drug Administration Schedule, Female, United Kingdom, Humans, Male, Middle Aged, Prognosis, Reference Values, Retrospective Studies, Fatty Acids, Omega-3, Survival Rate, Treatment Outcome, Risk Assessment, Patient Selection, Secondary Prevention
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
