Genome-wide analysis indicates more Asian than Melanesian ancestry of Polynesians
Open accessAbstract
Analyses of mitochondrial DNA (mtDNA) and nonrecombining Y chromosome (NRY) variation in the same populations are sometimes concordant but sometimes discordant. Perhaps the most dramatic example known of the latter concerns Polynesians, in which about 94% of Polynesian mtDNAs are of East Asian origin, while about 66% of Polynesian Y chromosomes are of Melanesian origin. Here we analyze on a genome-wide scale, to our knowledge for the first time, the origins of the autosomal gene pool of Polynesians by screening 377 autosomal short tandem repeat (STR) loci in 47 Pacific Islanders and compare the results with those obtained from 44 Chinese and 24 individuals from Papua New Guinea. Our data indicate that on average about 79% of the Polynesian autosomal gene pool is of East Asian origin and 21% is of Melanesian origin. The genetic data thus suggest a dual origin of Polynesians with a high East Asian but also considerable Melanesian component, reflecting sex-biased admixture in Polynesian history in agreement with the Slow Boat model. More generally, these results also demonstrate that conclusions based solely on uniparental markers, which are frequently used in population history studies, may not accurately reflect the history of the autosomal gene pool of a population.
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Kayser et al. identified 79% Asian and 21% Melanesian ancestry for Polynesians using 377 microsatellite markers in 47 Pacific Islanders.
“Recently, Kayser et al. [32] surveyed the nuclear genome with 377 microsatellite markers in 47 Pacific Islanders and identified 79% Asian and 21% Melanesian proportions of ancestry for Polynesians.”
From Population Genetic Structure and Origins of Native Hawaiians in the Multiethnic Cohort Study (2012) · cites this paper as [32]
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- Authors
- Kayser, M., Lao, O., Saar, K., Brauer, S., Wang, X., Nürnberg, P., Trent, R. J., & Stoneking, M.
- Affiliations
- Erasmus MC (NL)
- Max Delbrück Center (DE)
- Netherlands Forensic Institute (NL)
- Fu Wai Hospital (CN)
- University of Cologne (DE)
- The University of Sydney (AU)
- Max Planck Institute for Evolutionary Anthropology (DE)
- Corresponding author
- Kayser, Manfred
- Venue
- The American Journal of Human Genetics
- Publisher
- Elsevier BV
- Published
- 2008-01
- Volume
- 82
- Issue
- 1
- Pages
- 194-198
- ISSN
- 0002-9297 (ISSN-L)
- PMC
- PMC2253960
- OpenAlex
- W1984706655
- Cited by
- 174
- References
- 31
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 57 · 2023: 2 · 2022: 1 · 2021: 4 · 2020: 7 · 2019: 2 · 2018: 9 · 2017: 7 · 2016: 5 · 2015: 7 · 2014: 6 · 2013: 8 · 2012: 9
- FWCI
- 8.76
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- The American Journal of Human Genetics (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
- RePub (Erasmus University Rotterdam) (submittedVersion, other-oa)
- Max Planck Institute for Plasma Physics (submittedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- RePub (Erasmus University Rotterdam) (submittedVersion)
- Funders
- Max-Planck-Gesellschaft
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Forensic and Genetic Research
- Social Sciences › Geography, Planning and Development › Pacific and Southeast Asian Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
- Keywords
- Polynesians, East Asian ancestry, sex-biased admixture, Pacific Islanders, microsatellite markers, uniparental markers, demographic history, Chinese, Papua New Guinea
- MeSH terms
- DNA, Mitochondrial, Genetics, Medical, Humans, Microsatellite Repeats, Chromosomes, Human, Y, Asian People, Native Hawaiian or Other Pacific Islander
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