Phosphodiesterase 8B Gene Variants Are Associated with Serum TSH Levels and Thyroid Function

Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

Benjamini, Y., & Hochberg, Y. (1995) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1995.tb02031.x · Cited by 109,482 · see citing works

Quantifying heterogeneity in a meta‐analysis

Higgins, J. P. T., & Thompson, S. G. (2002) · Statistics in Medicine · doi:10.1002/sim.1186 · Cited by 36,763 · see citing works

A haplotype map of the human genome

The International HapMap Consortium (2005) · Nature · doi:10.1038/nature04226 · Cited by 5,858 · see citing works

Merlin—rapid analysis of dense genetic maps using sparse gene flow trees

Abecasis, G. R., Cherny, S. S., Cookson, W., & Cardon, L. R. (2001) · Nature Genetics · doi:10.1038/ng786 · Cited by 3,323 · see citing works

Multipoint Quantitative-Trait Linkage Analysis in General Pedigrees

Almasy, L. A., & Blangero, J. (1998) · The American Journal of Human Genetics · doi:10.1086/301844 · Cited by 3,007 · see citing works

Physiological and Molecular Basis of Thyroid Hormone Action

Yen, P. M. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.3.1097 · Cited by 2,011 · see citing works

Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use

Bender, A. T., & Beavo, J. A. (2006) · Pharmacological Reviews · doi:10.1124/pr.58.3.5 · Cited by 1,787 · see citing works

Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits

Scuteri, A., Sanna, S., Chen, W.-M., Uda, M., Albai, G., Strait, J., Najjar, S., Nagaraja, R., Orrú, M., Usala, G., et al. (2007) · PLoS Genetics · doi:10.1371/journal.pgen.0030115 · Cited by 1,724 · see citing works

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

Willer, C. J., Sanna, S., Jackson, A. U., Scuteri, A., Bonnycastle, L. L., Clarke, R., Heath, S. C., Timpson, N. J., Najjar, S. S., Stringham, H. M., et al. (2008) · Nature Genetics · doi:10.1038/ng.76 · Cited by 1,585 · see citing works

Construction of multilocus genetic linkage maps in humans.

Lander, E. S., & Green, P. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.8.2363 · Cited by 1,440 · see citing works

The Syndromes of Resistance to Thyroid Hormone*

Refetoff, S., Weiss, R. E., & Usala, S. J. (1993) · Endocrine Reviews · doi:10.1210/edrv-14-3-348 · Cited by 873 · see citing works

Subsystems Contributing to the Decline in Ability to Walk: Bridging the Gap Between Epidemiology and Geriatric Practice in the InCHIANTI Study

Ferrucci, L., Bandinelli, S., Benvenuti, E., Iorio, A. D., Macchi, C., Harris, T. B., & Guralnik, J. M. (2000) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2000.tb03873.x · Cited by 797 · see citing works

GOLD—Graphical Overview of Linkage Disequilibrium

Abecasis, G. R., & Cookson, W. (2000) · Bioinformatics · doi:10.1093/bioinformatics/16.2.182 · Cited by 776 · see citing works

Narrow Individual Variations in Serum T₄and T₃in Normal Subjects: A Clue to the Understanding of Subclinical Thyroid Disease

Andersen, S., Pedersen, K. M., Bruun, N. H., & Laurberg, P. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.3.8165 · Cited by 686 · see citing works

Genome-wide association study shows <i>BCL11A</i> associated with persistent fetal hemoglobin and amelioration of the phenotype of β-thalassemia

Uda, M., Galanello, R., Sanna, S., Lettre, G., Sankaran, V. G., Chen, W., Usala, G., Busonero, F., Maschio, A., Albai, G., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711566105 · Cited by 672 · see citing works

The Thyrotropin Receptor and the Regulation of Thyrocyte Function and Growth*

Vassart, G., & Dumont, J. E. (1992) · Endocrine Reviews · doi:10.1210/edrv-13-3-596 · Cited by 642 · see citing works

Heritability of Cardiovascular and Personality Traits in 6,148 Sardinians

Pilia, G., Chen, W., Scuteri, A., Orrù, M., Albai, G., Dei, M., Lai, S., Usala, G., Lai, M., Loi, P., et al. (2006) · PLoS Genetics · doi:10.1371/journal.pgen.0020132 · Cited by 543 · see citing works

The Thyroid: A Fundamental and Clinical Text

WERNER, S. C. (1956) · The American Journal of the Medical Sciences · doi:10.1097/00000441-195610000-00020 · Cited by 460 · see citing works

A Mutation in the POU-Homeodomain of Pit-1 Responsible for Combined Pituitary Hormone Deficiency

Radovick, S., Nations, M., Du, Y., Berg, L. A., Weintraub, B. D., & Wondisford, F. E. (1992) · Science · doi:10.1126/science.257.5073.1115 · Cited by 447 · see citing works

Family-Based Association Tests for Genomewide Association Scans

Chen, W., & Abecasis, G. R. (2007) · The American Journal of Human Genetics · doi:10.1086/521580 · Cited by 398 · see citing works

Common variants in the GDF5-UQCC region are associated with variation in human height

Sanna, S., Jackson, A., Nagaraja, R., Willer, C. J., Chen, W., Bonnycastle, L. L., Shen, H., Timpson, N. J., Lettre, G., Usala, G., et al. (2008) · Nature Genetics · doi:10.1038/ng.74 · Cited by 391 · see citing works

Thyroid-Pituitary Interaction: Feedback Regulation of Thyrotropin Secretion by Thyroid Hormones

Bleich, H. L., Moore, M. J., & Larsen, P. R. (1982) · New England Journal of Medicine · doi:10.1056/nejm198201073060107 · Cited by 357 · see citing works

A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia

Horvath, A., Boikos, S., Giatzakis, C., Robinson-White, A., Groussin, L., Griffin, K. J., Stein, E., Levine, E., Delimpasi, G., Hsiao, H. P., et al. (2006) · Nature Genetics · doi:10.1038/ng1809 · Cited by 352 · see citing works

The GLUT9 Gene Is Associated with Serum Uric Acid Levels in Sardinia and Chianti Cohorts

Li, S., Sanna, S., Maschio, A., Busonero, F., Usala, G., Mulas, A., Lai, S., Dei, M., Orrù, M., Albai, G., et al. (2007) · PLoS Genetics · doi:10.1371/journal.pgen.0030194 · Cited by 305 · see citing works

Cyclic-3′,5′-nucleotide phosphodiesterase isozymes in cell biology and pathophysiology of the kidney

Dousa, T. P. (1999) · Kidney International · doi:10.1046/j.1523-1755.1999.00233.x · Cited by 277 · see citing works

Mutation in PDE8B, a Cyclic AMP–Specific Phosphodiesterase in Adrenal Hyperplasia

Horvath, A., Verónica Mericq, G., & Stratakis, C. A. (2008) · New England Journal of Medicine · doi:10.1056/nejmc0706182 · Cited by 190 · see citing works

Age‐Associated Declines in Complex Walking Task Performance: The Walking InCHIANTI Toolkit

Shumway‐Cook, A., Guralnik, J. M., Phillips, C. L., Coppin, A. K., Ciol, M. A., Bandinelli, S., & Ferrucci, L. (2006) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2006.00962.x · Cited by 182 · see citing works

Somatostatin and Somatostatin Receptor Physiology

Barnett, P. S. (2003) · Endocrine · doi:10.1385/endo:20:3:255 · Cited by 175 · see citing works

IRAK-M Is Involved in the Pathogenesis of Early-Onset Persistent Asthma

Balaci, L., Spada, M. C., Olla, N., Sole, G., Loddo, L., Anedda, F., Naitza, S., Zuncheddu, M. A., Maschio, A., Altea, D., et al. (2007) · The American Journal of Human Genetics · doi:10.1086/518259 · Cited by 169 · see citing works

The Genetic Basis of Thyroid Autoimmunity

Jacobson, E. M., & Tomer, Y. (2007) · Thyroid · doi:10.1089/thy.2007.0153 · Cited by 150 · see citing works

Cloning and characterization of PDE7B, a cAMP-specific phosphodiesterase

Hetman, J., Soderling, S. H., Glavas, N. A., & Beavo, J. A. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.1.472 · Cited by 148 · see citing works

Alterations on phosphodiesterase type 7 and 8 isozyme mRNA expression in Alzheimer’s disease brains examined by in situ hybridization

Pérez-Torres, S., Cortés, R., Tolnay, M., Probst, A., Palacios, J. M., & Mengod, G. (2003) · Experimental Neurology · doi:10.1016/s0014-4886(03)00042-6 · Cited by 134 · see citing works

Molecular Cloning and Characterization of Human PDE8B, a Novel Thyroid-Specific Isozyme of 3′,5′-Cyclic Nucleotide Phosphodiesterase

Hayashi, M., Matsushima, K., Ohashi, H., Tsunoda, H., Murase, S., Kawarada, Y., & Tanaka, T. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.9379 · Cited by 130 · see citing works

Thyrocyte-specific Gq/G11 deficiency impairs thyroid function and prevents goiter development

Kero, J., Ahmed, K., Wettschureck, N., Tunaru, S., Wintermantel, T., Greiner, E., Schütz, G., & Offermanns, S. (2007) · Journal of Clinical Investigation · doi:10.1172/jci30380 · Cited by 124 · see citing works

cAMP Is a Ligand for the Tandem GAF Domain of Human Phosphodiesterase 10 and cGMP for the Tandem GAF Domain of Phosphodiesterase 11

Groß-Langenhoff, M., Hofbauer, K., Weber, J. H., Schultz, A. C. F., & Schultz, J. E. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m511468200 · Cited by 122 · see citing works

The genetic response to short-term interventions affecting cardiovascular function: Rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study

Mitchell, B. D., McArdle, P. F., Shen, H., Rampersaud, E., Pollin, T. I., Bielak, L. F., Jaquish, C. E., Douglas, J. A., Roy‐Gagnon, M., Sack, P., et al. (2008) · American Heart Journal · doi:10.1016/j.ahj.2008.01.019 · Cited by 118 · see citing works

Short Term Feedback Regulation of cAMP in FRTL-5 Thyroid Cells

Oki, N., Takahashi, S., Hidaka, H., & Conti, M. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.15.10831 · Cited by 107 · see citing works

Therapeutic benefit of PDE4 inhibitors in inflammatory diseases.

Dastidar, S. G., Rajagopal, D., & Ray, A. (2007) · PubMed · Cited by 105 · see citing works

Genetic Variation in Adiponectin Receptor 1 and Adiponectin Receptor 2 Is Associated With Type 2 Diabetes in the Old Order Amish

Damcott, C., Ott, S. H., Pollin, T. I., Reinhart, L. J., Wang, J., O’Connell, J. R., Mitchell, B. D., & Shuldiner, A. R. (2005) · Diabetes · doi:10.2337/diabetes.54.7.2245 · Cited by 96 · see citing works

Low Prevalence of Thyrotropin Receptor Mutations in a Large Series of Subjects with Sporadic and Familial Nonautoimmune Subclinical Hypothyroidism

Tonacchera, M., Perri, A., Marco, G. D., Agretti, P., Banco, M., Cosmo, C. D., Grasso, L., Vitti, P., Chiovato, L., & Pinchera, A. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1243 · Cited by 72 · see citing works

Molecular cloning and characterization of human PDE8B, a novel thyroid-specific isozyme of 3',5'-cyclic nucleotide phosphodiesterase

林, 正. (1998) · doi:10.11501/3151235 · Cited by 70 · see citing works

Induction of Specific Phosphodiesterase Isoforms by Constitutive Activation of the cAMP Pathway in Autonomous Thyroid Adenomas1

Persani, L., Lania, A. G., Alberti, L., Romoli, R., Mantovani, G., Filetti, S., Spada, A., & Conti, M. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.8.6712 · Cited by 69 · see citing works

Thyroid Hormone Synthesis

Kopp, P. A., & Solís‐S, J. C. (2009) · Elsevier eBooks · doi:10.1016/b978-1-4160-4745-2.00003-1 · Cited by 65 · see citing works

Induction of Specific Phosphodiesterase Isoforms by Constitutive Activation of the cAMP Pathway in Autonomous Thyroid Adenomas

Persani, L. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.85.8.2872 · Cited by 50 · see citing works

Diminished Phosphodiesterase-8B Potentiates Biphasic Insulin Response to Glucose

Dov, A., Abramovitch, E., Warwar, N., & Nesher, R. (2007) · Endocrinology · doi:10.1210/en.2007-0968 · Cited by 48 · see citing works

Relevant cAMP-Specific Phosphodiesterase Isoforms in Human Pituitary: Effect of Gsα Mutations

Persani, L., Borgato, S., Lania, A. G., Filopanti, M., Mantovani, G., Conti, M., & Spada, A. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.8.7779 · Cited by 45 · see citing works

Genomic organization, chromosomal localization, and alternative splicing of the human phosphodiesterase 8B gene

Hayashi, M., Shimada, Y., Nishimura, Y., Hama, T., & Tanaka, T. (2002) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)02371-9 · Cited by 45 · see citing works

A Genome-Wide Scan for Autoimmune Thyroiditis in the Old Order Amish: Replication of Genetic Linkage on Chromosome 5q11.2-q14.3

Allen, E. M., Hsueh, W.-C., Sabra, M. M., Pollin, T. I., Ladenson, P. W., Silver, K. D., Mitchell, B. D., & Shuldiner, A. R. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-020634 · Cited by 40 · see citing works

A central negative feedback action of thyroid hormones on thyrotropin- releasing hormone secretion

Dahl, G. E., Evans, N. P., Thrun, L. A., & Karsch, F. J. (1994) · Endocrinology · doi:10.1210/endo.135.6.7988422 · Cited by 39 · see citing works

Exploring the genetics of longevity in the Old Order Amish

Sorkin, J. D., Post, W. S., Pollin, T. I., O’Connell, J. R., Mitchell, B. D., & Shuldiner, A. R. (2004) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2004.08.027 · Cited by 37 · see citing works

The Thyroid: A Fundamental and Clinical Text

(1956) · Diabetes · doi:10.2337/diab.5.4.330a · Cited by 11 · see citing works

Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues

Lakics, V., Karran, E. H., & Boess, F. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2010.05.004 · Cited by 468 · see citing works

2012 ETA Guidelines: The Use of L-T4 + L-T3 in the Treatment of Hypothyroidism

Wiersinga, W. M., Duntas, L., Fadeyev, V., Nygaard, B., & Vanderpump, M. P. J. (2012) · European Thyroid Journal · doi:10.1159/000339444 · Cited by 427 · see citing works

Age-Related Changes in Thyroid Function: A Longitudinal Study of a Community-Based Cohort

Bremner, A. P., Feddema, P., Leedman, P. J., Brown, S. J., Beilby, J. P., Lim, E. M., Wilson, S. G., O'Leary, P. C., & Walsh, J. P. (2012) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jc.2011-3020 · Cited by 336 · see citing works

Clinical and Molecular Genetics of the Phosphodiesterases (PDEs)

Azevedo, M. F., Faucz, F. R., Bimpaki, E. I., Horvath, A., Levy, I., de Alexandre, R. B., Ahmad, F., Manganiello, V. C., & Stratakis, C. A. (2013) · Endocrine Reviews · doi:10.1210/er.2013-1053 · Cited by 326 · see citing works

Treatment with thyroid hormone

Biondi, B., & Wartofsky, L. (2014) · Endocrine Reviews · doi:10.1210/er.2013-1083 · Cited by 259 · see citing works

Variants Near FOXE1 Are Associated with Hypothyroidism and Other Thyroid Conditions: Using Electronic Medical Records for Genome- and Phenome-wide Studies

Denny, J. C., Crawford, D. C., Ritchie, M. D., Bielinski, S. J., Basford, M., Bradford, Y., Chai, H. S., Bastarache, L. A., Zuvich, R. L., Peissig, P. L., et al. (2011) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2011.09.008 · Cited by 249 · see citing works

Discovery of common variants associated with low TSH levels and thyroid cancer risk

Guðmundsson, J., Sulem, P., Gudbjartsson, D. F., Jonasson, J. G., Másson, G., He, H., Jónasdóttir, Á., Sigurðsson, Á., Stacey, S., Johannsdottir, H., et al. (2012) · Nature Genetics · doi:10.1038/ng.1046 · Cited by 246 · see citing works

A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function

Porcu, E., Medici, M., Pistis, G., Volpato, C. B., Wilson, S. G., Cappola, A. R., Bos, S. D., Deelen, J., den Heijer, M., Freathy, R. M., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003266 · Cited by 229 · see citing works

Treatment for primary hypothyroidism: current approaches and future possibilities

Vaidya, B., Chakera, A. J., & Pearce, S. H. S. (2011) · Drug Design Development and Therapy · doi:10.2147/dddt.s12894 · Cited by 202 · see citing works

A Genome-Wide Association Scan on the Levels of Markers of Inflammation in Sardinians Reveals Associations That Underpin Its Complex Regulation

Naitza, S., Porcu, E., Steri, M., Taub, D. D., Mulas, A., Xiao, X., Strait, J., Dei, M., Lai, S., Busonero, F., et al. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002480 · Cited by 148 · see citing works

Novel Associations for Hypothyroidism Include Known Autoimmune Risk Loci

Eriksson, N., Tung, J. Y., Kiefer, A. K., Hinds, D. A., Francke, U., Mountain, J. L., & Do, C. B. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034442 · Cited by 145 · see citing works

Molecular aspects of thyroid hormone transporters, including MCT8, MCT10, and OATPs, and the effects of genetic variation in these transporters

van der Deure, W. M., Peeters, R. P., & Visser, T. J. (2010) · Journal of Molecular Endocrinology · doi:10.1677/jme-09-0042 · Cited by 130 · see citing works

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia

Sanna, S., Busonero, F., Maschio, A., McArdle, P. F., Usala, G., Dei, M., Lai, S., Mulas, A., Piras, M. G., Perseu, L., et al. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp203 · Cited by 126 · see citing works

Paradigm shifts in thyroid hormone replacement therapies for hypothyroidism

Wiersinga, W. M. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2013.258 · Cited by 114 · see citing works

Genetics and phenomics of hypothyroidism due to TSH resistance

Persani, L., Calebiro, D., Cordella, D., Weber, G., Gelmini, G., Libri, D., de Filippis, T., & Bonomi, M. (2010) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2010.01.008 · Cited by 107 · see citing works

Whole-genome sequence-based analysis of thyroid function

Taylor, P. N., Porcu, E., Chew, S., Campbell, P. J., Traglia, M., Brown, S. J., Mullin, B. H., Shihab, H. A., Min, J., Walter, K., et al. (2015) · Nature Communications · doi:10.1038/ncomms6681 · Cited by 104 · see citing works

Subclinical Hypothyroidism in Children and Adolescents: A Wide Range of Clinical, Biochemical, and Genetic Factors Involved

Rapa, A., Monzani, A., Moia, S., Vivenza, D., Bellone, S., Petri, A., Teofoli, F., Cassio, A., Cesaretti, G., Corrias, A., et al. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-0375 · Cited by 103 · see citing works

Thyroid function in childhood obesity and metabolic comorbidity

Pacifico, L., Anania, C., Ferraro, F., Andreoli, G. M., & Chiesa, C. (2011) · Clinica Chimica Acta · doi:10.1016/j.cca.2011.11.013 · Cited by 99 · see citing works

Genome-Wide Association Studies in an Isolated Founder Population from the Pacific Island of Kosrae

Lowe, J. K., Maller, J., Pe’er, I., Neale, B. M., Salit, J., Kenny, E. E., Shea, J., Burkhardt, R., Smith, J. G., Ji, W., et al. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000365 · Cited by 98 · see citing works

Genetic determination of the hypothalamic–pituitary–thyroid axis: where do we stand?

Medici, M., Visser, W. E., Visser, T. J., & Peeters, R. P. (2015) · Endocrine Reviews · doi:10.1210/er.2014-1081 · Cited by 92 · see citing works

Novel insights into thyroid hormones from the study of common genetic variation

Dayan, C. M., & Panicker, V. (2009) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2009.19 · Cited by 110 · see citing works

Phosphodiesterase 4B inhibition: a potential novel strategy for treating pulmonary fibrosis

Kolb, M., Crestani, B., & Maher, T. M. (2023) · European Respiratory Review · doi:10.1183/16000617.0206-2022 · Cited by 85 · see citing works

Kinetic and Structural Studies of Phosphodiesterase-8A and Implication on the Inhibitor Selectivity

Wang, H., Yan, Z., Yang, S., Cai, J., Robinson, H. H., & Ke, H. (2008) · Biochemistry · doi:10.1021/bi801487x · Cited by 82 · see citing works

Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels

Pichler, I., Minelli, C., Sanna, S., Tanaka, T., Schwienbacher, C., Naitza, S., Porcu, E., Pattaro, C., Busonero, F., Zanon, A., et al. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq552 · Cited by 76 · see citing works

Thyroid Function Changes in the Elderly and Their Relationship to Cardiovascular Health: A Mini-Review

Barbesino, G. (2018) · Gerontology · doi:10.1159/000490911 · Cited by 73 · see citing works

Gender-specific regulation of response to thyroid hormone in aging

Suzuki, S., Nishio, S., Takeda, T., & Komatsu, M. (2012) · Thyroid Research · doi:10.1186/1756-6614-5-1 · Cited by 72 · see citing works

Genetic Predisposition to Familial Nonmedullary Thyroid Cancer: An Update of Molecular Findings and State-of-the-Art Studies

Bonora, E., Tallini, G., & Romeo, G. (2010) · Journal of Oncology · doi:10.1155/2010/385206 · Cited by 71 · see citing works

A large-scale association analysis of 68 thyroid hormone pathway genes with serum TSH and FT4 levels

Medici, M., van der Deure, W. M., Verbiest, M., Vermeulen, S. H., Hansen, P. S., Kiemeney, L. A., Hermus, A. R. M. M., Breteler, M. M., Hofman, A., Hegedüs, L., et al. (2011) · European Journal of Endocrinology · doi:10.1530/eje-10-1130 · Cited by 68 · see citing works

Phosphodiesterase function and endocrine cells: links to human disease and roles in tumor development and treatment

Levy, I., Horvath, A., Azevedo, M. F., de Alexandre, R. B., & Stratakis, C. A. (2011) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2011.10.003 · Cited by 65 · see citing works

Transcriptome Analyses Identify a Metabolic Gene Signature Indicative of Dedifferentiation of Papillary Thyroid Cancer

Ma, B., Jiang, H., Wen, D., Hu, J., Han, L., Liu, W., Xu, W., Xiao Hua, S. H. I., Wei, W., Liao, T., et al. (2019) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2018-02686 · Cited by 62 · see citing works

Genetics of thyroid function and disease.

Panicker, V. (2011) · Europe PMC (PubMed Central) · Cited by 61 · see citing works

Phosphodiesterase type 5 and cancers: progress and challenges

Barone, I., Giordano, C., Bonofiglio, D., Andò, S., & Catalano, S. (2017) · Oncotarget · doi:10.18632/oncotarget.21837 · Cited by 61 · see citing works

Contribution of ATM and FOXE1 (TTF2) to risk of papillary thyroid carcinoma in Belarusian children exposed to radiation

Damiola, F., Byrnes, G. B., Moissonnier, M., Pertesi, M., Deltour, I., Fillon, A., Calvez‐Kelm, F. L., Tenet, V., McKay‐Chopin, S., McKay, J., et al. (2013) · International Journal of Cancer · doi:10.1002/ijc.28483 · Cited by 61 · see citing works

A Locus on Chromosome 1p36 Is Associated with Thyrotropin and Thyroid Function as Identified by Genome-wide Association Study

Panicker, V., Wilson, S. G., Walsh, J. P., Richards, J. B., Brown, S. J., Beilby, J. P., Bremner, A., Surdulescu, G. L., Qweitin, E., Gillham‐Nasenya, I., et al. (2010) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2010.08.005 · Cited by 55 · see citing works

Assay of Thyroid Hormones and Related Substances

Spencer, C. A. (2013) · Europe PMC (PubMed Central) · Cited by 53 · see citing works

Inactivation of Pde8b enhances memory, motor performance, and protects against age‐induced motor coordination decay

Tsai, L.-C. L., Chan, G. C. ‐., Nangle, S. N., Shimizu‐Albergine, M., Jones, G. L., Storm, D. R., Beavo, J. A., & Zweifel, L. S. (2012) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2012.00836.x · Cited by 48 · see citing works

Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function

Rawal, R., Teumer, A., Völzke, H., Wallaschofski, H., Ittermann, T., Åsvold, B. O., Bjøro, T., Greiser, K. H., Tiller, D., Werdan, K., et al. (2012) · Human Molecular Genetics · doi:10.1093/hmg/dds136 · Cited by 46 · see citing works

The Genetic Basis of Thyroid Function: Novel Findings and New Approaches

Kuś, A., Chaker, L., Teumer, A., Peeters, R. P., & Medici, M. (2020) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/clinem/dgz225 · Cited by 44 · see citing works

The FOXE1 locus is a major genetic determinant for familial nonmedullary thyroid carcinoma

Bonora, E., Rizzato, C., Diquigiovanni, C., Oudot‐Mellakh, T., Campa, D., Vargiolu, M., Guedj, M., McKay, J., Romeo, G. C., Canzian, F., et al. (2013) · International Journal of Cancer · doi:10.1002/ijc.28543 · Cited by 44 · see citing works

Phosphodiesterases in endocrine physiology and disease

Vezzosi, D., & Bertherat, J. Y. (2011) · European Journal of Endocrinology · doi:10.1530/eje-10-1123 · Cited by 44 · see citing works

Identification and Consequences of Polymorphisms in the Thyroid Hormone Receptor Alpha and Beta Genes

Sørensen, H., van der Deure, W. M., Hansen, P. S., Peeters, R. P., Breteler, M. M. B., Kyvik, K. O., Sørensen, T. I. A., Hegedűs, L. D., & Visser, T. J. (2008) · Thyroid · doi:10.1089/thy.2008.0236 · Cited by 41 · see citing works

A meta-analysis of the associations between common variation in the PDE8B gene and thyroid hormone parameters, including assessment of longitudinal stability of associations over time and effect of thyroid hormone replacement

Taylor, P. N., Panicker, V., Sayers, A., Shields, B., Iqbal, A., Bremner, A. P., Beilby, J. P., Leedman, P. J., Hattersley, A. T., Vaidya, B., et al. (2011) · European Journal of Endocrinology · doi:10.1530/eje-10-0938 · Cited by 41 · see citing works

The relationship of deiodinase 1 genotype and thyroid function to lifetime history of major depression in three independent populations

Philibert, R. A., Beach, S. R. H., Gunter, T. D., Todorov, A. A., Brody, G. H., Vijayendran, M., Elliott, L., Hollenbeck, N. J., Russell, D. W., & Cutrona, C. E. (2011) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.31200 · Cited by 41 · see citing works

Genetic Variants Associated with Serum Thyroid Stimulating Hormone (TSH) Levels in European Americans and African Americans from the eMERGE Network

Malinowski, J. R., Denny, J. C., Bielinski, S. J., Basford, M., Bradford, Y., Peissig, P. L., Carrell, D., Crosslin, D. R., Pathak, J., Rasmussen, L. V., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111301 · Cited by 41 · see citing works

A genome-wide association study on thyroid function and anti-thyroid peroxidase antibodies in Koreans

Kwak, S. H., Park, Y. J., Go, M. J., Lee, K. E., Kim, S., Choi, H. S., Kim, T. H., Choi, S. H., Lim, S. K., Kim, K. W., et al. (2014) · Human Molecular Genetics · doi:10.1093/hmg/ddu145 · Cited by 38 · see citing works

cAMP/PKA signaling defects in tumors: Genetics and tissue-specific pluripotential cell-derived lesions in human and mouse

Stratakis, C. A. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2013.01.015 · Cited by 38 · see citing works

Quantitative assessment of preoperative serum thyrotropin level and thyroid cancer

Zheng, J., Li, C., Lu, W., Wang, C., & Ai, Z. (2016) · Oncotarget · doi:10.18632/oncotarget.9201 · Cited by 38 · see citing works

Applying semantic web technologies for phenome-wide scan using an electronic health record linked Biobank

Pathak, J., Kiefer, R. C., Bielinski, S. J., & Chute, C. G. (2012) · Journal of Biomedical Semantics · doi:10.1186/2041-1480-3-10 · Cited by 37 · see citing works

p54nrb/NONO Regulates Cyclic AMP-Dependent Glucocorticoid Production by Modulating Phosphodiesterase mRNA Splicing and Degradation

Lu, J., & Sewer, M. B. (2015) · Molecular and Cellular Biology · doi:10.1128/mcb.00993-14 · Cited by 34 · see citing works

Physiology of the Hypothalamic-Pituitary-Thyroid Axis

Mariotti, S., & Beck‐Peccoz, P. (2016) · Cited by 35 · see citing works

Genetic Susceptibility to Joint Occurrence of Polycystic Ovary Syndrome and Hashimoto’s Thyroiditis: How Far Is Our Understanding?

Żeber‐Lubecka, N., & Hennig, E. E. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.606620 · Cited by 33 · see citing works

Genome-wide association study identifies a novel susceptibility gene for serum TSH levels in Chinese populations

Zhan, M., Chen, G., Pan, C., Gu, Z., Zhao, S., Liu, W. Y., Wang, H.-N., Ye, X.-P., Xie, H.-J., Yu, S.-S., et al. (2014) · Human Molecular Genetics · doi:10.1093/hmg/ddu250 · Cited by 32 · see citing works

Linkage and association of successful aging to the 6q25 region in large Amish kindreds

Edwards, D. R. V., Gilbert, J. R., Hicks, J. E., Myers, J. L., Jiang, L., Cummings, A. C., Guo, S., Gallins, P. J., Konidari, I., Caywood, L. J., et al. (2012) · AGE · doi:10.1007/s11357-012-9447-1 · Cited by 32 · see citing works

Genetics of thyroid function

Medici, M., Visser, T. J., & Peeters, R. P. (2017) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2017.04.002 · Cited by 32 · see citing works

Setpoints and susceptibility: do small differences in thyroid function really matter?*

Walsh, J. P. (2011) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2011.04036.x · Cited by 29 · see citing works

Genome-wide association analysis suggests novel loci for Hashimoto’s thyroiditis

Brčić, L., Barić, A., Gračan, S., Brekalo, M., Kaličanin, D., Gunjača, I., Lovrić, V. T., Tokić, S., Radman, M., Škrabić, V., et al. (2018) · Journal of Endocrinological Investigation · doi:10.1007/s40618-018-0955-4 · Cited by 30 · see citing works

Genetic Loci Linked to Pituitary-Thyroid Axis Set Points: A Genome-Wide Scan of a Large Twin Cohort

Panicker, V., Wilson, S. G., Spector, T. D., Brown, S. J., Kato, B. S., Reed, P., Falchi, M., Richards, J. B., Surdulescu, G. L., Lim, E. M., et al. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-2650 · Cited by 30 · see citing works

Phosphodiesterase 8B Gene Polymorphism Is Associated with Subclinical Hypothyroidism in Pregnancy

Shields, B. M., Freathy, R. M., Knight, B. A., Hill, A., Weedon, M. N., Frayling, T. M., Hattersley, A. T., & Vaidya, B. (2009) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jc.2009-1298 · Cited by 35 · see citing works

Migraine and thyroid dysfunction: Co‐occurrence, shared genes and biological mechanisms

Tasnim, S., & Nyholt, D. R. (2023) · European Journal of Neurology · doi:10.1111/ene.15753 · Cited by 27 · see citing works

Thyroid Function and Longevity: New Insights into an Old Dilemma

Peeters, R. P. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2198 · Cited by 23 · see citing works

Heredity and lifestyle in the determination of between-subject variation in thyroid hormone levels in euthyroid men

Roef, G. L., Taes, Y., Toye, K. R. C., Goemaere, S., Fiers, T., Verstraete, A., & Kaufman, J. (2013) · European Journal of Endocrinology · doi:10.1530/eje-13-0265 · Cited by 23 · see citing works

Comparative Transcriptomic Analysis of the Pituitary Gland between Cattle Breeds Differing in Growth: Yunling Cattle and Leiqiong Cattle

Lu, X., Arbab, A. A. I., Zhang, Z., Fan, Y., Han, Z., Gao, Q., Sun, Y., & Yang, Z. (2020) · Animals · doi:10.3390/ani10081271 · Cited by 22 · see citing works

Transcriptomic Signature of Human Embryonic Thyroid Reveals Transition From Differentiation to Functional Maturation

Dom, G., Dmitriev, P., Lambot, M.-A., Vliet, G. V., Glinoer, D., Libert, F., Lefort, A., Dumont, J. E., & Maenhaut, C. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.669354 · Cited by 20 · see citing works

Association of established hypothyroidism-associated genetic variants with Hashimoto’s thyroiditis

Barić, A., Brčić, L., Gračan, S., Lovrić, V. T., Gunjača, I., Šimunac, M., Brekalo, M., Boban, M., Polašek, O., Barbalić, M., et al. (2017) · Journal of Endocrinological Investigation · doi:10.1007/s40618-017-0660-8 · Cited by 19 · see citing works

Contaminants in Atlantic walruses in Svalbard Part 2: Relationships with endocrine and immune systems

Routti, H., Diot, B., Panti, C., Duale, N., Fossi, M. C., Harju, M., Kovacs, K. M., Lydersen, C., Scotter, S. E., Villanger, G. D., et al. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2018.11.097 · Cited by 19 · see citing works

A novel mutation of PDE 8 B Gene in a J apanese family with autosomal‐dominant striatal degeneration

Azuma, R., Ishikawa, K., Hirata, K., Hashimoto, Y., Takahashi, M., Ishii, K., Inaba, A., Yokota, T., & Orimo, S. (2015) · Movement Disorders · doi:10.1002/mds.26345 · Cited by 18 · see citing works

Impact of phosphodiesterase 8B gene rs4704397 variation on thyroid homeostasis in childhood obesity

Grandone, A., Perrone, L., Cirillo, G., Sessa, A. D., Corona, A. M., Amato, A., Cresta, N., Romano, T., & del Giudice, E. M. (2011) · European Journal of Endocrinology · doi:10.1530/eje-11-0703 · Cited by 17 · see citing works

Refolding and kinetic characterization of the phosphodiesterase-8A catalytic domain

Yan, Z., Wang, H., Cai, J., & Ke, H. (2008) · Protein Expression and Purification · doi:10.1016/j.pep.2008.10.005 · Cited by 17 · see citing works

A genome-wide association study of thyroid stimulating hormone and free thyroxine in Danish children and adolescents

Nielsen, T. R. H., Appel, E. V. R., Svendstrup, M., Ohrt, J. D., Dahl, M., Fonvig, C. E., Hollensted, M., Have, C. T., Kadarmideen, H. N., Pedersen, O. B., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0174204 · Cited by 15 · see citing works

INTEGRATING CLINICAL LABORATORY MEASURES AND ICD-9 CODE DIAGNOSES IN PHENOME-WIDE ASSOCIATION STUDIES

Verma, A., Leader, J. B., Verma, S. S., Frase, A., Wallace, J. R., DUDEK, S. M., Lavage, D. R., Hout, C. V. V., Dewey, F. E., PENN, J., et al. (2015) · Pacific Symposium on Biocomputing (PSB) · doi:10.1142/9789814749411_0016 · Cited by 15 · see citing works

Haplotype Analysis of the Promoter Region of Phosphodiesterase Type 8B ( PDE8B ) in Correlation with Inactivating PDE8B Mutation and the Serum Thyroid-Stimulating Hormone Levels

Horvath, A., Faucz, F. R., Finkielstain, G. P., Nikita, M. E., Rothenbühler, A., Almeida, M. Q., Verónica Mericq, G., & Stratakis, C. A. (2010) · Thyroid · doi:10.1089/thy.2009.0260 · Cited by 15 · see citing works

Uncovering the shared genetic components of thyroid disorders and reproductive health

Figuerêdo, J., Krebs, K., Pujol‐Gualdo, N., Haller, T., Võsa, U., Volke, V., Laisk, T., Mägi, R., Metspalu, A., Milani, L. A., et al. (2024) · European Journal of Endocrinology · doi:10.1093/ejendo/lvae094 · Cited by 13 · see citing works

A Comprehensive Metabolic Modeling of Thyroid Pathway in Relation to Thyroid Pathophysiology and Therapeutics

Gupta, M., Singh, D. B., Shukla, R., & Misra, K. (2013) · OMICS A Journal of Integrative Biology · doi:10.1089/omi.2013.0007 · Cited by 13 · see citing works

Cyclic AMP, Protein Kinase A, and Phosphodiesterases: Proceedings of an International Workshop

Stratakis, C. A. (2012) · Hormone and Metabolic Research · doi:10.1055/s-0031-1301327 · Cited by 12 · see citing works

Genetic features of thyroid hormone receptors

Rebaï, M., Kallel, I., & Rebaï, A. (2012) · Journal of Genetics · doi:10.1007/s12041-012-0179-x · Cited by 11 · see citing works

Thyroid-stimulating Hormone

Sarapura, V. D., Gordon, D. F., & Samuels, M. H. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-380926-1.10006-9 · Cited by 11 · see citing works

The associations of polymorphisms of TSH receptor and thyroid hormone receptor genes with L-thyroxine treatment in hypothyroid patients

Al-Azzam, S. I., Alzoubi, K. H., Khabour, O. F., & AlAzzeh, O. (2014) · HORMONES · doi:10.14310/horm.2002.1488 · Cited by 11 · see citing works

The Phosphodiesterase 8B Gene rs4704397 is Associated with Thyroid Function, Risk of Myocardial Infarction, and Body Height: The Tromsø Study

Jorde, R., Schirmer, H., Wilsgaard, T., Joakimsen, R. M., Mathiesen, E. B., Njølstad, I., Løchen, M., Figenschau, Y., Svartberg, J. B., Hutchinson, M. S., et al. (2013) · Thyroid · doi:10.1089/thy.2013.0177 · Cited by 11 · see citing works

Sex, Genetics, and the Control of Thyroxine and Thyrotropin in Mice

McLachlan, S. M., Hamidi, S., Aliesky, H. A., Williams, R. W., & Rapoport, B. (2014) · Thyroid · doi:10.1089/thy.2014.0003 · Cited by 11 · see citing works

Pediatric reference values of TSH should be personalized according to BMI and ethnicity

Oron, T., Lazar, L., Feldhamer, I., Manor, M., Koren-Morag, N., Tenenbaum, A., & Meyerovitch, J. (2020) · European Journal of Endocrinology · doi:10.1530/eje-20-0239 · Cited by 10 · see citing works

Persistent symptoms in euthyroid Hashimoto’s thyroiditis: current hypotheses and emerging management strategies

Zhang, H., Tong, W., Zeng, W., Luo, H., Zhang, L., Feng, J., Xiao, Y., & Wang, G. A. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1627787 · Cited by 12 · see citing works

Thyroid-Stimulating Hormone

Sarapura, V. D., & Samuel, M. H. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804169-7.00006-4 · Cited by 10 · see citing works

Regulation of the Pituitary-Thyroid Axis in Adulthood Is Not Related to Birth Weight: Evidence from Extremely Birth Weight–Discordant Monozygotic Danish Twin Pairs

Frost, M., Petersen, I., Hegedűs, L. D., Christiansen, L., Brix, T. H., & Christensen, K. (2012) · Thyroid · doi:10.1089/thy.2012.0095 · Cited by 10 · see citing works

Phosphodiesterase 8B gene polymorphism in women with recurrent miscarriage: A retrospective case control study

Granfors, M., Karypidis, H., Hosseini, F., Skjöldebrand‐Sparre, L., Stavreus-Evers, A. C., Bremme, K. A., Landgren, B.-M., Poromaa, I. S., Wikström, A., & Åkerud, H. (2012) · BMC Medical Genetics · doi:10.1186/1471-2350-13-121 · Cited by 9 · see citing works

Ecological Genetics of Thyroid Hormone Physiology in Humans and Wild Animals

Ishikawa, A., & Kitano, J. (2012) · InTech eBooks · doi:10.5772/45969 · Cited by 8 · see citing works

Association between rs12045440 Polymorphism in the CAPZB Intron and Serum TSH Concentrations in Chinese Thyroid Tumor Patients

Feng, S., Lin, S., Zou, J., Wang, Y., Ji, Q., & Lv, Z. (2015) · International Journal of Endocrinology · doi:10.1155/2015/250542 · Cited by 7 · see citing works

Genetic associations with neonatal thyroid-stimulating hormone levels

Alul, F. Y., Shchelochkov, O. A., Berberich, S. L., Murray, J. C., & Ryckman, K. K. (2013) · Pediatric Research · doi:10.1038/pr.2013.18 · Cited by 8 · see citing works

Gene network analysis of small molecules with autoimmune disease associated genes predicts a novel strategy for drug efficacy

Maiti, A. K., & Nath, S. K. (2012) · Autoimmunity Reviews · doi:10.1016/j.autrev.2012.09.001 · Cited by 7 · see citing works

Distinct Genetic Signatures for Variability in Total and Free Serum Thyroxine Levels in Four Sets of Recombinant Inbred Mice

McLachlan, S. M., Lu, L., Aliesky, H. A., Williams, R. W., & Rapoport, B. (2011) · Endocrinology · doi:10.1210/en.2010-1138 · Cited by 6 · see citing works

Common genetic variants in pituitary–thyroid axis genes and the risk of differentiated thyroid cancer

Pastor, S., Akdi, A., González, E. R., Castell‐Conesa, J., Biarnés, J., Marcos, R., & Velázquez, A. (2012) · Endocrine Connections · doi:10.1530/ec-12-0017 · Cited by 6 · see citing works

Physiology of the Hypothalamic-Pituitary Thyroidal System.

Mariotti, S. (2011) · UNICA IRIS Institutional Research Information System (University of Cagliari) · Cited by 6 · see citing works

Genetic variation in phosphodiesterase (PDE) 7B in chronic lymphocytic leukemia: overview of genetic variants of cyclic nucleotide PDEs in human disease

Peiró, A. M., Tang, C., Murray, F., Zhang, L., Brown, L. M., Chou, D., Rassenti, L. Z., Kipps, T. J., & Insel, P. A. (2011) · Journal of Human Genetics · doi:10.1038/jhg.2011.80 · Cited by 6 · see citing works

Linkage and association analysis of hyperthyrotropinaemia in an Alpine population reveal two novel loci on chromosomes 3q28-29 and 6q26-27

Volpato, C. B., Grandi, A. D., Gögele, M., Taliun, D., Fuchsberger, C., Facheris, M., Minelli, C., Pattaro, C., Pramstaller, P. P., & Hicks, A. A. (2011) · Journal of Medical Genetics · doi:10.1136/jmg.2010.088583 · Cited by 6 · see citing works

Plasma TSH and cardiovascular disease in the general population: A Mendelian randomization study of 105,224 individuals

Dalila, N., Frikke‐Schmidt, R., Nordestgaard, B. G., & Tybjærg‐Hansen, A. (2023) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2023.05.018 · Cited by 5 · see citing works

Frequency and effect on serum TSH of phosphodiesterase 8B (PDE8B) gene polymorphisms in patients with sporadic nonautoimmune subclinical hypothyroidism

Agretti, P., Marco, G. D., Cosmo, C. D., Bagattini, B., Ferrarini, E., Montanelli, L., Vitti, P., & Tonacchera, M. (2014) · Journal of Endocrinological Investigation · doi:10.1007/s40618-013-0036-7 · Cited by 5 · see citing works

Genetic Linkages for Thyroxine Released in Response to Thyrotropin Stimulation in Three Sets of Recombinant Inbred Mice Provide Evidence for Shared and Novel Genes Controlling Thyroid Function

Hamidi, S., Aliesky, H. A., Williams, R. W., Rapoport, B., & McLachlan, S. M. (2012) · Thyroid · doi:10.1089/thy.2012.0338 · Cited by 5 · see citing works

An Erythropoietin-Independent Mechanism of Erythrocytic Precursor Proliferation Underlies Hypoxia Tolerance in Sea Nomads

Ilardo, M. A., dos Santos, M. C. F., Beverborg, N. G., Rajan, M., Said, M. A., Verweij, N., van der Harst, P., van der Meer, P., & Leibold, E. A. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2021.760851 · Cited by 5 · see citing works

Common genetic variants associated with thyroid function may be risk alleles for Hashimoto's disease and Graves' disease

Campbell, P. J., Brix, T. H., Wilson, S. G., Ward, L., Hui, J., Beilby, J. P., Hegedűs, L. D., & Walsh, J. P. (2015) · Clinical Endocrinology · doi:10.1111/cen.12746 · Cited by 5 · see citing works

Thyroid-Stimulating Hormone

Gordon, D. F., Sarapura, V. D., Samuels, M. H., & Ridgway, E. C. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-5583-9.00073-3 · Cited by 5 · see citing works

Strength of Genetic Associations with Thyrotropin Values Differs Between Populations with Similarity to African and European Reference Populations

Wade, A. N., Guare, L. A., Hayat, M., Straub, P., Gao, Z., Medici, M., Teumer, A., Davis, L. K., Ramsay, M., Ritchie, M. D., et al. (2025) · Thyroid · doi:10.1089/thy.2024.0525 · Cited by 4 · see citing works

ARTICLE Phosphodiesterase 8B Gene Variants Are Associated with Serum TSH Levels and Thyroid Function

Arnaud-Lopez, L., Usala, G., Ceresini, G., Mitchell, B. D., Pilia, M. G., Piras, M. G., Sestu, N., Maschio, A., Busonero, F., Dei, M., et al. (2014)

Phosphodiesterase 8B (PDE8B) gene variants and TSH levels

Mariotti, S., S, N., & A., C. (2010) · UNICA IRIS Institutional Research Information System (University of Cagliari)

Haplotype Analysis of the Promoter Region of Phosphodiesterase Type 8B ( PDE8B ) in Correlation with Inactivating PDE8B Mutation and the Serum Thyroid-Stimulating Hormone Levels

Horvath, A., Faucz, F. R., Finkielstain, G. P., Nikita, M. E., Rothenbühler, A., Almeida, M. Q., Verónica Mericq, G., & Stratakis, C. A. (2010) · Thyroid · doi:10.1089/thy.2009.0260 · Cited by 15 · see citing works

Impact of rs2046045 SNP in PDE8B on TSH Levels: Insights into Genetic Susceptibility to Hypothyroidism

Khan, S., Rani, N., Yadav, A., & Gupta, R. (2024) · Biochemical Genetics · doi:10.1007/s10528-024-11005-y

A meta-analysis of the associations between common variation in the PDE8B gene and thyroid hormone parameters, including assessment of longitudinal stability of associations over time and effect of thyroid hormone replacement

Taylor, P. N., Panicker, V., Sayers, A., Shields, B., Iqbal, A., Bremner, A. P., Beilby, J. P., Leedman, P. J., Hattersley, A. T., Vaidya, B., et al. (2011) · European Journal of Endocrinology · doi:10.1530/eje-10-0938 · Cited by 41 · see citing works