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Antiphospholipid antibody profile based obstetric outcomes of primary antiphospholipid syndrome: the PREGNANTS study
Open accessAbstract
Background Antiphospholipid syndrome is an autoimmune, hypercoagulable state that is caused by antiphospholipid antibodies. Anticardiolipin antibodies, anti-β2 glycoprotein-I, and lupus anticoagulant are the main autoantibodies found in antiphospholipid syndrome. Despite the amassed body of clinical knowledge, the risk of obstetric complications that are associated with specific antibody profile has not been well-established. Objective The purpose of this study was to assess the risk of obstetric complications in women with primary antiphospholipid syndrome that is associated with specific antibody profile. Study design The Pregnancy In Women With Antiphospholipid Syndrome study is a multicenter, retrospective, cohort study. Diagnosis and classification of antiphospholipid syndrome were based on the 2006 International revised criteria. All women included in the study had at least 1 clinical criteria for antiphospholipid syndrome, were positive for at least 1 antiphospholipid antibody (anticardiolipin antibodies, anti-β2 glycoprotein-I, and/or lupus anticoagulant), and were treated with low-dose aspirin and prophylactic low molecular weight heparin from the first trimester. Only singleton pregnancies with primary antiphospholipid syndrome were included. The primary outcome was live birth, defined as any delivery of a live infant after 22 weeks gestation. The secondary outcomes were preeclampsia with and without severe features, intrauterine growth restriction, and stillbirth.…
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“In observational studies, treatment with LDA and therapeutic dose heparin was associated with live births in 79% of pregnancies on average.52 61–64”
From EULAR recommendations for the management of antiphospholipid syndrome in adults (2019) · cites this paper as [64]
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Cites
von Elm, E., Altman, D. G., Egger, M., Pocock, S. J., Gøtzsche, P. C., Vandenbroucke, J. P., & Initiative, F. T. S. (2007) · PLoS Medicine · doi:10.1371/journal.pmed.0040296 · Cited by 23,020
von Elm, E., Altman, D. G., Egger, M., Pocock, S. J., Gøtzsche, P. C., & Vandenbroucke, J. P. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61602-x · Cited by 21,320
MIYAKIS, S., LOCKSHIN, M. D., ATSUMI, T., BRANCH, D. W., BREY, R. L., CERVERA, R., DERKSEN, R. H. W. M., DE GROOT, P. G., KOIKE, T., MERONI, P. L., et al. (2006) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2006.01753.x · Cited by 7,203
(2013) · doi:10.1097/01.aog.0000437382.03963.88 · Cited by 3,961
Levine, J. S., Branch, D. W., & Rauch, J. (2002) · New England Journal of Medicine · doi:10.1056/nejmra002974 · Cited by 1,524
Update of the guidelines for lupus anticoagulant detection
PENGO, V., TRIPODI, A., REBER, G., RAND, J. H., ORTEL, T. L., GALLI, M., & DE GROOT, P. G. (2009) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2009.03555.x · Cited by 1,197
Thrombophilia in pregnancy: a systematic review
Robertson, L., Wu, O., Langhorne, P., Twaddle, S., Clark, P., Lowe, G. D. O., Walker, I. D., Greaves, M., Brenkel, I., Regan, L., et al. (2005) · British Journal of Haematology · doi:10.1111/j.1365-2141.2005.05847.x · Cited by 853
Lees, C. C., Marlow, N., van Wassenaer-Leemhuis, A., Arabin, B., Bilardo, C. M., Brezinka, C., Calvert, S., Derks, J. B., Diemert, A., Duvekot, J. J., et al. (2015) · The Lancet · doi:10.1016/s0140-6736(14)62049-3 · Cited by 479
Self-citationHarris, E. N. (1990) · American Journal of Clinical Pathology · doi:10.1093/ajcp/94.4.476 · Cited by 416
Branch, D. W., Peaceman, A. M., Druzin, M. L., Silver, R. K., El-Sayed, Y. Y., Silver, R. M., Esplin, M. S., Spinnato, J. A., & Harger, J. H. (2000) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(00)70500-x · Cited by 315
Recurrent pregnancy loss with antiphospholipid antibody: a systematic review of therapeutic trials
Empson, M. B. (2002) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(01)01646-5 · Cited by 293
Regression modelling and other methods to control confounding
McNamee, R. (2005) · Occupational and Environmental Medicine · doi:10.1136/oem.2002.001115 · Cited by 251
Alijotas‐Reig, J., Esteve‐Valverde, E., Ferrer‐Oliveras, R., Comet, L. S., Lefkou, E. E., MEKINIAN, A., Belizna, C. C., Ruffatti, A., Tincani, A., Marozio, L., et al. (2019) · Autoimmunity Reviews · doi:10.1016/j.autrev.2018.12.006 · Cited by 220
Self-citation(2012) · Obstetrics and Gynecology · doi:10.1097/01.aog.0000423816.39542.0f · Cited by 209
Dewhurst, C. (1964) · The Lancet · doi:10.1016/s0140-6736(64)90397-6 · Cited by 187
Kim, M., Buyon, J. P., Guerra, M. M., Rana, S., Zhang, D., Laskin, C. A., Petri, M., Lockshin, M. D., Sammaritano, L. R., Branch, D. W., et al. (2015) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.09.066 · Cited by 176
LUPUS ANTICOAGULANT AND RECURRENT FETAL LOSS: SUCCESSFUL TREATMENT WITH GAMMAGLOBULIN
Carreras, L., Pérez, G., Vega, H. R., & CASAVILLA, F. A. (1988) · The Lancet · doi:10.1016/s0140-6736(88)92859-0 · Cited by 173
Alijotas‐Reig, J., Ferrer‐Oliveras, R., Ruffatti, A., Tincani, A., Lefkou, E. E., Bertero, M. T., Coloma, E., Carolis, S. D., Espinosa, G., Rovere, P. Q., et al. (2014) · Autoimmunity Reviews · doi:10.1016/j.autrev.2014.12.010 · Cited by 152
Self-citationScott, J. R., Branch, D. W., Kochenour, N. K., & Ward, K. J. (1988) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(88)90411-5 · Cited by 136
Smith, A. H., & Bates, M. N. (1992) · Epidemiology · doi:10.1097/00001648-199209000-00011 · Cited by 128
Intravenous immunoglobulin therapy for the antiphospholipid syndrome in pregnancy
Spinnato, J. A., Clark, A. L., Pierangeli, S. S., & Harris, E. N. (1995) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(95)90595-2 · Cited by 114
Association of Anticardiolipin Antibodies With Preeclampsia
do Prado, A. D., Piovesan, D. M., Staub, H. L., & Horta, B. L. (2010) · Obstetrics and Gynecology · doi:10.1097/aog.0b013e3181fe02ec · Cited by 110
Recurrent pregnancy loss with antiphospholipid antibody: a systematic review of therapeutic trials
Rote, N. S. (2002) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(02)02061-6 · Cited by 77
Chighizola, C. B., Ubiali, T., & Meroni, P. L. (2015) · Journal of Immunology Research · doi:10.1155/2015/951424 · Cited by 67
Coumarin derivatives and breast-feeding
Clark, S. L. (2000) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(00)00809-7 · Cited by 66
Blackhouse, G., Gaebel, K., Xie, F., Campbell, K., Assasi, N., Tarride, J., O’Reilly, D. J., Chalk, C., Levine, M., & Goeree, R. A. (2010) · Cost Effectiveness and Resource Allocation · doi:10.1186/1478-7547-8-14 · Cited by 58
Yelnik, C. M., Porter, T. F., Branch, D. W., Laskin, C. A., Merrill, J. T., Guerra, M. M., Lockshin, M. D., Buyon, J. P., Petri, M., Sammaritano, L. R., et al. (2016) · Arthritis & Rheumatology · doi:10.1002/art.39668 · Cited by 54
Recurrent first trimester spontaneous abortion associated with antiphospholipid antibodies:
Marzusch, K., Dietl, J., Klein, R., Hornung, D., Neuer, A., & Berg, P. A. (1996) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016349609055029 · Cited by 52
Harris, E. N., & Pierangeli, S. S. (1998) · Scandinavian Journal of Rheumatology · doi:10.1080/03009742.1998.11720777 · Cited by 26
Anti‐β2 glycoprotein I antibodies and pregnancy outcome in antiphospholipid syndrome
Liu, X. L., Xiao, J., & Zhu, F. (2012) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.12038 · Cited by 10
Wilson (1999) · doi:10.1002/1529-0131(199907)42:7
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EULAR recommendations for the management of antiphospholipid syndrome in adults
Tektonidou, M. G., Andreoli, L., Limper, M., Amoura, Z., Cervera, R., Costedoat-Chalumeau, N., Cuadrado, M. J., Dörner, T., Ferrer-Oliveras, R., Hambly, K., et al. (2019) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2019-215213 · Cited by 1,318
Interferons and Proinflammatory Cytokines in Pregnancy and Fetal Development
Yockey, L. J., & Iwasaki, A. (2018) · Immunity · doi:10.1016/j.immuni.2018.07.017 · Cited by 588
Jung, E., Romero, R. J., Yeo, L., Gomez‐Lopez, N., Chaemsaithong, P., Jaovisidha, A., Gotsch, F., & Erez, O. (2022) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2021.11.1356 · Cited by 648
Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management
Knight, J. S., Branch, D. W., & Ortel, T. L. (2023) · BMJ · doi:10.1136/bmj-2021-069717 · Cited by 299
Malosso, E. R. M., Saccone, G., Tommaso, M. D., Roman, A., & Berghella, V. (2017) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.13151 · Cited by 259
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Metadata
- Authors
- Saccone, G., Berghella, V., Maruotti, G. M., Ghi, T., Rizzo, G., Simonazzi, G., Rizzo, N., Facchinetti, F., Dall’Asta, A., Visentin, S., Sarno, L., Xodo, S., Bernabini, D., Monari, F., Roman, A., Eke, A. C., Hoxha, A., Ruffatti, A., Schuit, E., & Martinelli, P.
- Affiliations
- University of Naples Federico II (IT)
- Thomas Jefferson University (US)
- University of Parma (IT)
- University of Rome Tor Vergata (IT)
- IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola (IT)
- University of Modena and Reggio Emilia (IT)
- University of Padua (IT)
- University of Udine (IT)
- Johns Hopkins University (US)
- Stanford Medicine (US)
- Corresponding author
- Saccone, Gabriele
- ORCID
- Venue
- American Journal of Obstetrics and Gynecology
- Publisher
- Elsevier BV
- Published
- 2017-05
- Volume
- 216
- Issue
- 5
- Pages
- 525.e1-525.e12
- ISSN
- 0002-9378 (ISSN-L)
- OpenAlex
- W2580867287
- Cited by
- 205
- References
- 31
- Citations by year
- 2026: 7 · 2025: 17 · 2024: 24 · 2023: 22 · 2022: 31 · 2021: 19 · 2020: 21 · 2019: 35 · 2018: 20 · 2017: 9
- FWCI
- 20.34
- Type
- journal article
- Language
- en
- Open access
- Licence
- Locations
- American Journal of Obstetrics and Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Cineca Institutional Research Information System (Tor Vergata University) (submittedVersion)
- Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna) (submittedVersion, cc-by-nc-nd)
- Utrecht University Repository (Utrecht University) (submittedVersion)
- IRIS UNIMORE (University of Modena and Reggio Emilia) (submittedVersion, cc-by)
- IRIS Research product catalog (Sapienza University of Rome) (submittedVersion)
- Padua Research Archive (University of Padova) (submittedVersion)
- Topics
- Health Sciences › Medicine › Rheumatology › Systemic Lupus Erythematosus Research
- Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Keywords
- primary antiphospholipid syndrome, pregnancy complications, live birth, preeclampsia, fetal growth restriction, stillbirth, anticardiolipin antibodies, anti-beta2-glycoprotein I antibodies, lupus anticoagulant, low-dose aspirin, low molecular weight heparin, pregnancy outcomes
- MeSH terms
- Adult, Anticoagulants, Aspirin, Female, Fetal Growth Retardation, Heparin, Low-Molecular-Weight, Humans, Italy, Platelet Aggregation Inhibitors, Pre-Eclampsia, Pregnancy, Pregnancy Complications, Retrospective Studies, Cohort Studies, Antiphospholipid Syndrome, Antibodies, Antiphospholipid, Stillbirth, Live Birth, beta 2-Glycoprotein I
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