Engineering Synechococcus sp. PCC 7002 for sustainable production of sucrose

What is the maximum efficiency with which photosynthesis can convert solar energy into biomass?

Zhu, X.-G., Long, S. P., & Ort, D. R. (2008) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2008.02.004 · Cited by 1,145 · see citing works

Rerouting Carbon Flux to Enhance Photosynthetic Productivity

Ducat, D. C., Avelar-Rivas, J. A., Way, J. C., & Silver, P. A. (2012) · Applied and Environmental Microbiology · doi:10.1128/aem.07901-11 · Cited by 362 · see citing works

Engineering Cyanobacteria To Synthesize and Export Hydrophilic Products

Niederholtmeyer, H., Wolfstädter, B. T., Savage, D. F., Silver, P. A., & Way, J. C. (2010) · Applied and Environmental Microbiology · doi:10.1128/aem.00202-10 · Cited by 243 · see citing works

Improved Free Fatty Acid Production in Cyanobacteria with Synechococcus sp. PCC 7002 as Host

Ruffing, A. M. (2014) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2014.00017 · Cited by 181 · see citing works

Osmotic adjustment and organic solute accumulation in unicellular cyanobacteria from freshwater and marine habitats

Reed, R. H., & Stewart, W. D. P. (1985) · Marine Biology · doi:10.1007/bf00393037 · Cited by 159 · see citing works

Engineering of photosynthetic mannitol biosynthesis from CO2 in a cyanobacterium

Jacobsen, J. H., & Frigaard, N. (2013) · Metabolic Engineering · doi:10.1016/j.ymben.2013.11.004 · Cited by 153 · see citing works

A synthetic, light-driven consortium of cyanobacteria and heterotrophic bacteria enables stable polyhydroxybutyrate production

Weiss, T. L., Young, E. J., & Ducat, D. C. (2017) · Metabolic Engineering · doi:10.1016/j.ymben.2017.10.009 · Cited by 152 · see citing works

Sucrose andSaccharomyces cerevisiae: a relationship most sweet

Marques, W. L., Raghavendran, V., Stambuk, B. U., & Gombert, A. K. (2015) · FEMS Yeast Research · doi:10.1093/femsyr/fov107 · Cited by 145 · see citing works

The potential of Synechococcus elongatus UTEX 2973 for sugar feedstock production

Song, K., Tan, X., Liang, Y., & Lü, X. (2016) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-016-7510-z · Cited by 135 · see citing works

Exploring the photosynthetic production capacity of sucrose by cyanobacteria

Du, W., Liang, F., Duan, Y., Tan, X., & Lü, X. (2013) · Metabolic Engineering · doi:10.1016/j.ymben.2013.05.001 · Cited by 133 · see citing works

Altered carbohydrate metabolism in glycogen synthase mutants of Synechococcus sp. strain PCC 7002: Cell factories for soluble sugars

Xu, Y., Guerra, T., Li, Z., Ludwig, M., Dismukes, G. C., & Bryant, D. A. (2012) · Metabolic Engineering · doi:10.1016/j.ymben.2012.12.002 · Cited by 131 · see citing works

Salt-Regulated Accumulation of the Compatible Solutes Sucrose and Glucosylglycerol in Cyanobacteria and Its Biotechnological Potential

Kirsch, F., Klähn, S., & Hagemann, M. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.02139 · Cited by 125 · see citing works

Enhanced production of sucrose in the fast-growing cyanobacterium Synechococcus elongatus UTEX 2973

Lin, P.-C., Zhang, F., & Pakrasi, H. B. (2020) · Scientific Reports · doi:10.1038/s41598-019-57319-5 · Cited by 124 · see citing works

Glucosylglycerate: a secondary compatible solute common to marine cyanobacteria from nitrogen‐poor environments

Klähn, S., Steglich, C., Hess, W. R., & Hagemann, M. (2009) · Environmental Microbiology · doi:10.1111/j.1462-2920.2009.02045.x · Cited by 121 · see citing works

Genetic tools for advancement of Synechococcus sp. PCC 7002 as a cyanobacterial chassis

Ruffing, A. M., Jensen, T. J., & Strickland, L. M. (2016) · Microbial Cell Factories · doi:10.1186/s12934-016-0584-6 · Cited by 110 · see citing works

Sucrose may play an additional role to that of an osmolyte in Synechocystis sp. PCC 6803 salt-shocked cells

Desplats, P., Folco, E. J. E., & Salerno, G. L. (2005) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2005.01.008 · Cited by 69 · see citing works

Sucrose addition directionally enhances bacterial community convergence and network stability of the shrimp culture system

Guo, H., Dong, P., Gao, F., Huang, L., Wang, S., Wang, R., Yan, M., & Zhang, D. (2022) · npj Biofilms and Microbiomes · doi:10.1038/s41522-022-00288-x · Cited by 65 · see citing works

Functional characterization of Synechococcus amylosucrase and fructokinase encoding genes discovers two novel actors on the stage of cyanobacterial sucrose metabolism

Perez-Cenci, M., & Salerno, G. L. (2014) · Plant Science · doi:10.1016/j.plantsci.2014.04.003 · Cited by 63 · see citing works

Unlocking the Constraints of Cyanobacterial Productivity: Acclimations Enabling Ultrafast Growth

Bernstein, H. C., McClure, R., Hill, E. A., Markillie, L. M., Chrisler, W., Romine, M. F., McDermott, J., Posewitz, M. C., Bryant, D. A., Konopka, A. E., et al. (2016) · mBio · doi:10.1128/mbio.00949-16 · Cited by 54 · see citing works

Systematic Approaches to Efficiently Produce 2,3-Butanediol in a Marine Cyanobacterium

Nozzi, N. E., Case, A. E., Carroll, A. L., & Atsumi, S. (2017) · ACS Synthetic Biology · doi:10.1021/acssynbio.7b00157 · Cited by 50 · see citing works

Cyanobacteria as cell factories: the roles of host and pathway engineering and translational research

Jaiswal, D., Sahasrabuddhe, D., & Wangikar, P. P. (2021) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2021.09.010 · Cited by 44 · see citing works

Engineering ethanol production in a marine cyanobacterium Synechococcus sp. PCC7002 through simultaneously removing glycogen synthesis genes and introducing ethanolgenic cassettes

Wang, M., Luan, G., & Lü, X. (2020) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2020.04.002 · Cited by 42 · see citing works

Expression of the ggpS Gene, Involved in Osmolyte Synthesis in the Marine Cyanobacterium Synechococcus sp. Strain PCC 7002, Revealed Regulatory Differences between This Strain and the Freshwater Strain Synechocystis sp. Strain PCC 6803

Engelbrecht, F., Marin, K., & Hagemann, M. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.11.4822-4829.1999 · Cited by 38 · see citing works

Inactivation of invertase enhances sucrose production in the cyanobacterium Synechocystis sp. PCC 6803

Kirsch, F., Luo, Q., Lü, X., & Hagemann, M. (2018) · Microbiology · doi:10.1099/mic.0.000708 · Cited by 35 · see citing works

Photosynthetic conversion of CO2 to hyaluronic acid by engineered strains of the cyanobacterium Synechococcus sp. PCC 7002

Zhang, L., Selão, T. T., Nixon, P. J., & Norling, B. (2019) · Algal Research · doi:10.1016/j.algal.2019.101702 · Cited by 35 · see citing works

A Highly Compatible Phototrophic Community for Carbon‐Negative Biosynthesis

Li, C., Wang, R., Wang, J., Liu, L., Li, H., Zheng, H., & Ni, J. (2022) · Angewandte Chemie International Edition · doi:10.1002/anie.202215013 · Cited by 26 · see citing works

Engineering of Synechococcus sp. strain PCC 7002 for the photoautotrophic production of light-sensitive riboflavin (vitamin B2)

Kachel, B., & Mack, M. (2020) · Metabolic Engineering · doi:10.1016/j.ymben.2020.09.010 · Cited by 25 · see citing works

Microbiota associated with the large-scale outdoor cultivation of the cyanobacterium Synechococcus sp. PCC 7002

Davies, F. K., Fricker, A. D., Robins, M. M., Dempster, T. A., McGowen, J. A., Charania, M. A., Beliaev, A. S., Lindemann, S. R., & Posewitz, M. C. (2021) · Algal Research · doi:10.1016/j.algal.2021.102382 · Cited by 20 · see citing works

Sugar Recognition by CscB and LacY

Sugihara, J., Смирнова, И. Н., Kasho, V. N., & Kaback, H. R. (2011) · Biochemistry · doi:10.1021/bi201592y · Cited by 18 · see citing works

One-step plasmid construction for generation of knock-out mutants in cyanobacteria: studies of glycogen metabolism in Synechococcus sp. PCC 7002

Jacobsen, J. H., Rosgaard, L., Sakuragi, Y., & Frigaard, N. (2011) · Photosynthesis Research · doi:10.1007/s11120-010-9613-1 · Cited by 15 · see citing works

Enhanced hydrogen production from sucrose-derived carbon quantum dots-supported Ru catalysts: A comparative study of KBH4 and NaBH4 hydrolysis

Onat, E., İzgi̇, M. S., Şahi̇n, Ö., & Ekıncı, S. (2025) · Renewable Energy · doi:10.1016/j.renene.2025.123692 · Cited by 31 · see citing works

Synthetic biology strategies for cyanobacterial systems to heterologously produce cyanobacterial natural products

Chen, M., Dhakal, D., Eckhardt, C. W., Luesch, H., & Ding, Y. (2025) · Natural Product Reports · doi:10.1039/d5np00009b · Cited by 21 · see citing works

Rewiring photosynthetic carbon flow: Engineered cyanobacterial factories for sustainable carbohydrate production and carbon-negative biomanufacturing

Bai, X., Zhang, G., Xu, L., Li, K., Zhang, M., & Huang, Y. (2025) · Bioresource Technology · doi:10.1016/j.biortech.2025.132850 · Cited by 11 · see citing works

Impact of irradiance and inorganic carbon availability on heterologous sucrose production in Synechococcus elongatus PCC 7942

Yun, L., Zegarac, R., & Ducat, D. C. (2024) · Frontiers in Plant Science · doi:10.3389/fpls.2024.1378573 · Cited by 6 · see citing works

Repurposing endogenous Type I-D CRISPR-Cas system for genome editing in Synechococcus sp. PCC7002

Yang, S., Zhang, Y., Li, C., & Tan, X. (2024) · Microbiological Research · doi:10.1016/j.micres.2024.127884 · Cited by 3 · see citing works

Carbon capture, storage, and utilization in cyanobacteria

Majhi, B. K. (2026) · Carbon Resources Conversion · doi:10.1016/j.crcon.2025.100388 · Cited by 2 · see citing works

Cyanobacteria as a Photosynthetic Chassis for Metabolic Pathway Engineering with Heterologous Gene Expression

Walshe, J., & Saha, S. K. (2026) · Current Issues in Molecular Biology · doi:10.3390/cimb48060638 · Cited by 1 · see citing works

Photosynthetic sorbitol production in Synechococcus sp. PCC 7002 is enhanced by addressing phosphatase promiscuity, nutrient availability and Calvin cycle bottlenecks

Kamoku, C., Bhavaraju, P., Travis, C., Taquillo, L., & Nielsen, D. R. (2025) · Metabolic Engineering · doi:10.1016/j.ymben.2025.04.008 · Cited by 1 · see citing works

Marine enzymes for food and animal feed: a systematic review of current applications and future perspectives

Pandey, D., Khanal, P., & Atanassova, M. (2026) · Future Foods · doi:10.1016/j.fufo.2026.100988 · Cited by 1 · see citing works

Marine Algae-Derived Materials for Environmental Applications

Malak, S., Ceballos, M. W. G., Ramesh, S. K., Rasgo, J. R. F., & Ajala, S. O. (2026) · Springer eBooks · doi:10.1007/978-981-92-0347-5_3

Exploring the photosynthetic production capacity of sucrose by cyanobacteria

Du, W., Liang, F., Duan, Y., Tan, X., & Lü, X. (2013) · Metabolic Engineering · doi:10.1016/j.ymben.2013.05.001 · Cited by 133 · see citing works

Sucrose secreted by the engineered cyanobacterium and its fermentability

Duan, Y., Luo, Q., Liang, F., & Lü, X. (2016) · Journal of Ocean University of China · doi:10.1007/s11802-016-3007-8 · Cited by 29 · see citing works

Enhanced production of sucrose in the fast-growing cyanobacterium Synechococcus elongatus UTEX 2973

Lin, P.-C., Zhang, F., & Pakrasi, H. B. (2020) · Scientific Reports · doi:10.1038/s41598-019-57319-5 · Cited by 124 · see citing works

Engineering Cyanobacteria Cell Factories for Photosynthetic Production of Sucrose

Zhang, S., Sun, H., Sun, J., Luo, Q., Luan, G., & Lü, X. (2021) · Springer eBooks · doi:10.1007/978-981-16-4873-1_17 · Cited by 4 · see citing works

基因工程聚球藻 PCC7942 产蔗糖研究

梁飞燕 (2013)