Objectively Measured Physical Activity and Mortality Risk Among American Adults
Abstract
Introduction One major limitation of prior studies examining the influence of physical activity on mortality is use of self-reported measures. This study examined the association between objectively measured light physical activity (LPA) and moderate to vigorous physical activity (MVPA) and all-cause mortality.Methods This study included 5,562 adults from the 2003-2006 National Health and Nutrition Examination Survey. LPA and MVPA were measured over 4-7 days using Actigraph AM-7164 accelerometers. For both activity intensities, the first quintile defined low participation and the remaining quintiles defined modest to high participation. Information on age, sex, race, SES, diet, smoking, and alcohol were collected and controlled for. Survival status through December 31, 2011, was determined. Average follow-up was 6.7 years. Data were analyzed in 2015.Results In women, the all-cause mortality hazard ratio (HR) was 0.58 (95% CI=0.38, 0.88) for modest to high LPA and 0.34 (95% CI=0.20, 0.57) for modest to high MVPA. Corresponding HRs in men were 1.02 (95% CI=0.64, 1.61) and 0.39 (95% CI=0.27, 0.56). Compared with women with a low LPA/low MVPA combination, mortality risk was reduced in the modest to high LPA/low MVPA (HR=0.42, 95% CI=0.26, 0.70), low LPA/modest to high MVPA (HR=0.16, 95% CI=0.07, 0.34), and modest to high LPA/modest to high MVPA (HR=0.17, 95% CI=0.09, 0.36) combinations. In men, mortality risk was not reduced with modest to high LPA/low MVPA.Conclusions MVPA was associated with a substantially lower mortality risk. LPA was associated with lower mortality risk, but only within women with low MVPA.
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Objectively measured physical activity levels, categorized into sedentary behaviour, light PA and MVPA, can be used to assess the risk of cardiovascular and all-cause death.
“Objectively measured PA levels, categorized into sedentary behaviour, light PA and MVPA, can be used to assess the risk of cardiovascular and all-cause death”
From Smart wearable devices in cardiovascular care: Where we are and how to move forward (2021) · cites this paper as [34]
Wearable-measured physical activity has an inverse dose-dependent relationship with all-cause mortality.
“Several studies have shown wearable-measured physical activity to have an inverse dose-dependent relationship with all-cause mortality5,34–38.”
From Smart wearable devices in cardiovascular care: Where we are and how to move forward (2021) · cites this paper as [34]
MVPA measured with triaxial accelerometers is associated with lower mortality than light physical activity or sedentary behaviour in several US cohorts and a Swedish population-based cohort.
“Moderate-to-vigorous physical activity (MVPA), measured with the use of triaxial accelerometers, was associated with a lower mortality than light physical activity or sedentary behaviour in several US cohorts and in a Swedish population-based cohort34–38.”
From Smart wearable devices in cardiovascular care: Where we are and how to move forward (2021) · cites this paper as [34]
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- Authors
- Borgundvaag, E., & Janssen, I.
- Affiliations
- Queen's University (CA)
- Corresponding author
- Janssen, Ian
- Venue
- American Journal of Preventive Medicine
- Publisher
- Elsevier BV
- Published
- 2017-01
- Volume
- 52
- Issue
- 1
- Pages
- e25-e31
- ISSN
- 0749-3797 (ISSN-L)
- OpenAlex
- W2546771643
- Cited by
- 38
- References
- 28
- Citations by year
- 2026: 4 · 2025: 2 · 2024: 1 · 2023: 3 · 2022: 3 · 2021: 3 · 2020: 7 · 2019: 5 · 2018: 10
- FWCI
- 4.02
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Preventive Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Canada Research Chairs
- Topics
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Keywords
- physical activity, all-cause mortality, light physical activity, moderate-to-vigorous physical activity, accelerometer-measured activity, sex differences, physical inactivity, mortality risk
- MeSH terms
- Adult, Aged, Female, Humans, Male, Middle Aged, Mortality, Prospective Studies, United States, Exercise, Young Adult, Actigraphy
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