Cited by 160Electronic Health Records SystemsClinical Laboratory Practices and Quality ControlPatient Safety and Medication Errors

The DOI matches its Crossref record; 26 of the 30 references it cites were found in a registry or an index; none of the 24 sources its claims cite is checked for support yet.

Notification of Abnormal Lab Test Results in an Electronic Medical Record: Do Any Safety Concerns Remain?

Open access

Abstract

Background: Follow-up of abnormal outpatient laboratory test results is a major patient safety concern. Electronic medical records can potentially address this concern through automated notification. We examined whether automated notifications of abnormal laboratory results (alerts) in an integrated electronic medical record resulted in timely follow-up actions. Methods: We studied four alerts: hemoglobin A1c (HbA1c) ≥15%, positive hepatitis C antibody (HCV), prostate specific antigen (PSA) ≥15 ng/mL, and thyroid stimulating hormone (TSH) ≥ 15 mIU/L. An alert tracking system determined whether the alert was acknowledged (i.e. provider clicked on and opened the message) within two weeks of transmission; acknowledged alerts were considered read. Within 30 days of result transmission, record review and provider contact determined follow-up actions (e.g. patient contact, treatment etc.). Multivariable logistic regression models analyzed predictors for lack of timely follow-up. Results: Between May 2008 and December 2008, 78,158 tests (HbA1c, HCV, TSH and PSA) were performed, of which 1163 (1.48%) were transmitted as alerts; 10.2% of these (119/1163) were unacknowledged. Timely follow-up was lacking in 79 (6.8%) and was statistically not different for acknowledged and unacknowledged alerts (6.4% vs. 10.1%; p =.13). Two-hundred two alerts (17.4% of 1163) arose from unnecessarily ordered (redundant) tests. Alerts for a new versus known diagnosis were more likely to lack timely follow-up (OR: 7.35; 95% CI: 4.16-12.97) whereas alerts related to redundant tests were less likely to lack timely follow-up (OR: 0.24; 95% CI: 0.07-0.84). Conclusions: Safety concerns related to timely patient follow-up remain despite automated notification of non-life threatening abnormal laboratory results in the outpatient setting.

Overview

Integrity signals

Registry

Crossref · 10.1016/j.amjmed.2009.07.027

Cites

26 of 26 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Verification

Claims the paper makes

14 Own result · 7 Not checked yet · 5 Own method · 5 Own interpretation

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  • It may state two separate claims as one. 8
  • Probably not a substantial claim. 5
12 of 12
  • The paper relies on this without support.

    Follow-up of an abnormal result depends on providers reviewing and acting on the electronic communication of the result.

    “Abnormal result follow-up, however, will occur only if electronic communication of test results (either through alerts or direct access of test result) is reviewed and acted upon by providers.”
  • The paper relies on this without support.

    A substantial share of outpatient lab results are not urgent enough to require verbal reporting to the ordering clinician.

    “many laboratory test results in the outpatient setting may not be immediately life threatening and hence not verbally reported to the ordering provider.”
2 of 2

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Metadata

Authors
Singh, H., Thomas, E. J., Sittig, D. F., Wilson, L., Espadas, D., Khan, M. M., & Petersen, L. A.
Affiliations
  • Michael E. DeBakey VA Medical Center (US)
  • Memorial Hermann (US)
Corresponding author
Singh, Hardeep
Venue
The American Journal of Medicine
Publisher
Elsevier BV
Published
2010-03
Volume
123
Issue
3
Pages
238-244
ISSN
0002-9343 (ISSN-L)
OpenAlex
W1981106602
Cited by
160
References
30
Citations by year
2026: 3 · 2025: 4 · 2024: 2 · 2023: 4 · 2022: 9 · 2021: 6 · 2020: 10 · 2019: 13 · 2018: 12 · 2017: 14 · 2016: 11 · 2015: 12 · 2014: 11 · 2013: 16 · 2012: 10
FWCI
28.08
Type
journal article
Language
en
Open access
Locations
  • The American Journal of Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • Digital Commons-TMC (Texas Medical Center) (submittedVersion)
Funders
  • National Institutes of Health (K23CA125585)
  • VA National Center for Patient Safety (R18 HS17244-02)
Topics
  • Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
  • Health Sciences › Health Professions › Medical Laboratory Technology › Clinical Laboratory Practices and Quality Control
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Patient Safety and Medication Errors
Keywords
laboratory abnormalities, electronic health records, patient safety, HbA1c, anti-HCV antibodies, prostate-specific antigen, thyroid-stimulating hormone, outpatient care
MeSH terms
Communication, Diagnostic Errors, Female, Follow-Up Studies, Hepatitis C, Humans, Male, Practice Patterns, Physicians', Primary Health Care, Retrospective Studies, United States, Medical Records Systems, Computerized

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