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Cited by 121Colorectal Cancer Surgical TreatmentsEnhanced Recovery After SurgeryGastric Cancer Management and Outcomes

The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

Anastomotic leakage after laparoscopic resection of rectal cancer: The impact of fibrin glue

Huh, Jung Wook, Kim, Hyeong Rok, Kim, Young Jin·2010·The American Journal of Surgery

Abstract

Background The aim of this study was to evaluate whether the use of fibrin glue as a sealant over an anastomosis is a risk factor for anastomotic leakage after laparoscopic rectal cancer surgery. Methods Prospective data were collected from 223 patients with rectal cancer who underwent laparoscopic resection without defunctioning stoma. Results A total of 104 patients underwent laparoscopic rectal resection, followed by the application of fibrin glue over the stapled anastomosis, while 119 underwent surgery alone. No difference in clinically significant leakage was observed between the fibrin and the nonfibrin groups (5.8% vs 10.9%, P = .169). In multivariate analysis, extraperitoneal tumor location and operation duration >220 minutes were independently associated with anastomotic leakage. Conclusions Significant predictors of anastomotic leakage include extraperitoneal tumor location and operation length >220 minutes. Fibrin glue application over the stapled anastomosis was not found to be significantly associated with anastomotic leakage.

Overview

Integrity signals

Registry

Crossref · 10.1016/j.amjsurg.2009.01.018

Cites

39 of 39 references verified0 citation errors · 0 not checkable

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Metadata

Authors
Huh, J. W., Kim, H. R., & Kim, Y. J.
Affiliations
Chonnam National University (KR)
Corresponding author
Kim, Hyeong Rok
Venue
The American Journal of Surgery
Publisher
Elsevier BV
Published
2010-04
Volume
199
Issue
4
Pages
435-441
ISSN
0002-9610 (ISSN-L)
OpenAlex
W2150925808
Cited by
114
References
38
Citations by year
2026: 5 · 2025: 1 · 2024: 3 · 2023: 10 · 2022: 9 · 2021: 3 · 2020: 10 · 2019: 7 · 2018: 4 · 2017: 4 · 2016: 8 · 2015: 3 · 2014: 14 · 2013: 11 · 2012: 7
FWCI
3.47
Type
journal article
Language
en
Open access
closed
Licence
  • www.elsevier.com/tdm/userlicense/1.0/ (tdm)
  • www.elsevier.com/legal/tdmrep-license (tdm)
Locations
  • The American Journal of Surgery (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Oncology › Colorectal Cancer Surgical Treatments
  • Health Sciences › Medicine › Surgery › Enhanced Recovery After Surgery
  • Health Sciences › Medicine › Oncology › Gastric Cancer Management and Outcomes
Keywords
anastomotic leakage, fibrin glue, rectal cancer, laparoscopic rectal resection, stapled anastomosis, operation duration, risk factors
MeSH terms
Adult, Aged, Aged, 80 and over, Anastomosis, Surgical, Female, Humans, Male, Middle Aged, Neoplasm Staging, Laparoscopy, Prospective Studies, Rectal Neoplasms, Risk Factors, Surgical Staplers, Surgical Wound Dehiscence, Time Factors, Tissue Adhesives, Fibrin Tissue Adhesive, Multivariate Analysis, Odds Ratio, Treatment Outcome

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CoChat. (2026). Citation check: Anastomotic leakage after laparoscopic resection of rectal cancer: The impact of fibrin glue. https://app.cochat.ai/papers/10.1016/j.amjsurg.2009.01.018
The paper
Huh, J. W., Kim, H. R., & Kim, Y. J. (2010). Anastomotic leakage after laparoscopic resection of rectal cancer: The impact of fibrin glue. The American Journal of Surgery. https://doi.org/10.1016/j.amjsurg.2009.01.018

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.