The DOI matches its Crossref record; 141 of the 142 references it cites were found in a registry or an index.
Impact of intermittent fasting on health and disease processes
Open accessAbstract
Humans in modern societies typically consume food at least three times daily, while laboratory animals are fed ad libitum. Overconsumption of food with such eating patterns often leads to metabolic morbidities (insulin resistance, excessive accumulation of visceral fat, etc.), particularly when associated with a sedentary lifestyle. Because animals, including humans, evolved in environments where food was relatively scarce, they developed numerous adaptations that enabled them to function at a high level, both physically and cognitively, when in a food-deprived/fasted state. Intermittent fasting (IF) encompasses eating patterns in which individuals go extended time periods (e.g., 16–48h) with little or no energy intake, with intervening periods of normal food intake, on a recurring basis. We use the term periodic fasting (PF) to refer to IF with periods of fasting or fasting mimicking diets lasting from 2 to as many as 21 or more days. In laboratory rats and mice IF and PF have profound beneficial effects on many different indices of health and, importantly, can counteract disease processes and improve functional outcome in experimental models of a wide range of age-related disorders including diabetes, cardiovascular disease, cancers and neurological disorders such as Alzheimer’s disease Parkinson’s disease and stroke. Studies of IF (e.g., 60% energy restriction on 2 days per week or every other day), PF (e.g., a 5 day diet providing 750–1100 kcal) and time-restricted feeding (TRF; limiting the daily period of food intake to 8 h or less) in normal and overweight human subjects have demonstrated efficacy for weight loss and improvements in multiple health indicators including insulin resistance and reductions in risk factors for cardiovascular disease. The cellular and molecular mechanisms by which IF improves health and counteracts disease processes involve activation of adaptive cellular stress response signaling pathways that enhance mitochondrial health, DNA repair and autophagy. PF also promotes stem cell-based regeneration as well as long-lasting metabolic effects. Randomized controlled clinical trials of IF versus PF and isoenergetic continuous energy restriction in human subjects will be required to establish the efficacy of IF in improving general health, and preventing and managing major diseases of aging.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source doesn’t support the claim as written.
In the citing paper
“Intermittent fasting can protect neurons in animal models of disease, reduce the number of dopaminergic neurons and improve motor function in Parkinson's disease.250”
From The role of gut dysbiosis in Parkinson’s disease: mechanistic insights and therapeutic options (2021) · cites this paper as [250]
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Intermittent fasting (e.g., one day without nutrients, followed by one day of ad libitum feeding) can avoid long-term weight loss induced by caloric restriction, yet increases lifespan in mice 148 and improves biomarkers of health in clinical trials 153,154 .”
From Hallmarks of aging: An expanding universe (2023) · cites this paper as [153]
Experimental — accuracy not yet measuredIn the citing paper
“Besides, inducing starvation via dietary regimens of alternate-day fasting [38] or intermittent fasting [39] has shown to reduce caloric intake and improve health markers related to cardiovascular risk in populations irrespective of obesity status.”
In the citing paper
“Therefore, healthy lifestyles, such as regular physical activity and healthy diet, are associated with weigh loss and reduced the risk of dementia by 0.68 times.375,376”
From Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances (2025) · cites this paper as [375]
In the citing paper
“Intermittent fasting in rodents improved insulin and leptin sensitivity increases ketone body levels and reduced adiposity and inflammation (235).”
From Metabolic Flexibility as an Adaptation to Energy Resources and Requirements in Health and Disease (2018) · cites this paper as [235]
In the citing paper
“Interestingly, time-restricted eating, which involves regular periods of fasting, has emerged in the last few years as an intervention with the potential to improve mitochondrial health and increase health span [170,171].”
From Mitochondrial Dynamics and Mitophagy in Skeletal Muscle Health and Aging (2021) · cites this paper as [171]
In the citing paper
“Various regimens of intermittent fasting have also been found to impact stem and progenitor cells in aged animals213.”
From Ageing and rejuvenation of tissue stem cells and their niches (2023) · cites this paper as [213]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Physiology and neurobiology of stress and adaptation: central role of the brain
McEwen, B. S. (2007) · Physiological Reviews · doi:10.1152/physrev.00041.2006 · Cited by 5,429 · cited 1×
“It has been hown that chronic uncontrollable stress reduces expression of he mineralocorticoid receptor (MR), while glucocorticoid receptor GR) levels are sustained, in hippocampal neurons which increases he vulnerability of the neurons to excitotoxic and metabolic stress McEwen, 2007).”
Renehan, A. G., Tyson, M., Egger, M., Heller, R. F., & Zwahlen, M. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60269-x · Cited by 5,219
Hatori, M., Vollmers, C., Zarrinpar, A., DiTacchio, L., Bushong, E. A., Gill, S., Leblanc, M., Chaix, A., Joens, M., Fitzpatrick, J. A. J., et al. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.04.019 · Cited by 1,986
Comparison of Weight-Loss Diets with Different Compositions of Fat, Protein, and Carbohydrates
Sacks, F. M., Bray, G. A., Carey, V. J., Smith, S. R., Ryan, D. H., Anton, S. D., McManus, K., Champagne, C. M., Bishop, L. M., Laranjo, N., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0804748 · Cited by 1,966 · cited 1×
“The differences in overall carbohydrate intake between the diet groups were modest (41% and 37% of energy for the two IF diets compared to 47% of energy for CER, which is unlikely to account for any differences in adherence and reductions in adiposity between the diets (Sacks et al., 2009).”
Long-term weight loss maintenance
Wing, R. R., & Phelan, S. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/82.1.222s · Cited by 1,941 · cited 1×
“Estimates of successful weight loss maintenance with CER (defined as >10% weight loss maintained at ≥12 months), vary between 20% and 50% (Anastasiou et al., 2015; Wing and Phelan, 2005), which depends on the level of ongoing support.”
Fasting: molecular mechanisms and clinical applications
Longo, V. D., & Mattson, M. P. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2013.12.008 · Cited by 1,425
Self-citationFasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan
Longo, V. D., & Panda, S. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.06.001 · Cited by 1,013
Self-citationCellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives
Mattson, M. P. (1997) · Physiological Reviews · doi:10.1152/physrev.1997.77.4.1081 · Cited by 1,006 · cited 1×
“A is generated from APP by sequential enzymatic cleavages by - and -secretases, and presenilin 1 is the enzymatic subunit of the -secretase enzyme complex (Mattson, 1997).”
Self-citationChaix, A., Zarrinpar, A., Miu, P., & Panda, S. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2014.11.001 · Cited by 956 · cited 4×
“…70% energy restriction every other day (Johnson t al., 2007; Varady et al., 2015); consuming only 500–700 cal two onsecutive days/week (Harvie et al., 2011); and restricting food ntake to a 6–8 h time period daily, which has also been termed time restricted feeding’ (TRF) (Chaix et al., 2014).”
InfluentialBrandhorst, S., Choi, I. Y., Wei, M., Cheng, C. W., Sedrakyan, S., Navarrete, G., Dubeau, L., Yap, L. P., Park, R., Vinciguerra, M., et al. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.05.012 · Cited by 850
Self-citation
Flagged first, then by citations
1 of the 142 references couldn’t be matched to a known paper.
Research works printed but not linked: 3
- Harvie, 2013, The effect of intermittent energy and carbohydrate restriction v. daily energy restriction on weight loss and metabolic disease risk markers in overweight women, Br. J. Nutr., 1
- Hill, 1989, Evaluation of an alternating-calorie diet with and without exercise in the treatment of obesity, Am. J. Clin. Nutr., 50, 248, 10.1093/ajcn/50.2.248 · DOI · Paper page
- WCRF. (1-6-2014). Systematic review on diet, nutrition, physical activity and survival and second cancers in breast cancer survivors. 7-1-2016. Ref Type: Online Source.
Cited by
Sorted by citations
Items 901–1,000 of 1,000
Helping your obese patient achieve a healthier weight
Eichorn (2021) · The Journal of Family Practice · doi:10.12788/jfp.0169 · Cited by 1
Efeitos do jejum intermitente na composição corporal e no rendimento físico
Correia, J. M., Pezarat‐Correia, P., & Mendonça, G. V. (2021) · Acta Portuguesa de Nutrição · doi:10.21011/apn.2021.2706
Aging, Cellular Senescence and Diabetes Mellitus: Clinicopathological Correlates, Trends and Targets
(2020) · Archives of Health Science · doi:10.31829/2641-7456/ahs2020-4(1)-131 · Cited by 2
Vilgis, T. A. (2022) · Springer eBooks · doi:10.1007/978-3-662-65108-7_6 · Cited by 1
Paulino, A. H. D. S., Todescato, A. P., Paula, B. M. D., Rodrigues, K. L., Silva, M. Z., Teodoro, M. A., Júnior, S. I. D. S., de Brito, T. R. P., & da Silva, W. R. (2023) · ARCHIVES OF HEALTH INVESTIGATION · doi:10.21270/archi.v12i.6097
Firmansyah, D., Karumiadri, M., & Maksum, M. N. R. (2023) · AT TA DIB · doi:10.21111/attadib.v18i1.9588 · Cited by 1
EFFECT OF MONDAY THURSDAY FASTING ON WORKING MEMORY AFTER ACUTE STRESS EXPOSURE
Faqih, A., Jusup, S. A., Wiyono, N., & Qadrijati, I. (2023) · International Journal of Islamic and Complementary Medicine · doi:10.55116/ijicm.v4i2.54 · Cited by 1
Obesity and Metabolic Syndrome
Katsagoni, C. N., Kokkinos, P. F., & Sidossis, L. S. (2023) · Wiley eBooks · doi:10.1002/9781119833475.ch18 · Cited by 1
Natur, Naturheilkunde, Naturwissenschaft: Vom Monte Verità zur Molekularmedizin
Michalsen, A. (2018) · Complementary Medicine Research · doi:10.1159/000490440 · Cited by 1
Hammer, S. S., Vieira, C. P., McFarland, D., Sandler, M., Levitsky, Y., Dorweiler, T. F., Lydic, T. A., Asare‐Bediako, B., Adu-Agyeiwaah, Y., Sielski, M. S., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/871822 · Cited by 1
Machine Learning to Summarize and Provide Context for Sleep and Eating SchedulesPreprint
Chen, T., Chen, Y., Gao, J., Gao, P., Moon, J. H., Ren, J.-Y., Zhu, R., Song, S., Clark, J. M., Bennett, W. L., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.12.31.424983 · Cited by 1
Xie, F., Fu, R., Hong, J., Ni, H., Yu, K., & Gu, L. (2022) · Research Square · doi:10.21203/rs.3.rs-1442328/v1 · Cited by 1
Effect of fasting therapy on vitamin D, vitality and quality of life. A randomized control trialPreprint
Tewani, G. R., Silwal, K., Sharma, G., Yadav, D., Siddiqui, A., Kriplani, S., Nathani, V. V., Sharma, N., Keswani, J., Sharma, H., et al. (2022) · medRxiv · doi:10.1101/2022.04.08.22273614 · Cited by 1
Chelikam, N., Akella, S. A., Lakhanpal, M. R., Lahori, S., Singh, A., Zafar, S., Shivashankar, P. G., Manjani, L., Ilyassov, R., Ali, A. I., et al. (2023) · Preprints.org · doi:10.20944/preprints202309.1017.v1 · Cited by 1
Rathomi, H. S. (2024) · Preprints.org · doi:10.20944/preprints202402.1492.v1
Intermittent fasting attenuates CNS inflammaging - rebalancing the transposonomePreprint
Cummins, M. J., Cresswell, E. T., & Smith, D. W. (2025) · Research Square · doi:10.21203/rs.3.rs-6165725/v1 · Cited by 1
Clarifying fasting-based dietary strategies: toward alignment with emerging consensus terminology
Mhamdi, S., Saad, H. B., & Ghram, A. (2025) · Libyan Journal of Medicine · doi:10.1080/19932820.2025.2573518 · Cited by 1
Arthrose multidimensional behandeln
Pinsger, M. (2017) · Manuelle Medizin · doi:10.1007/s00337-017-0246-8
Cararo-Lopes, M. M. (2017) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.42.2017.tde-14072017-092741
Aufbruch in der Fastentherapie
Michalsen, A. (2018) · Zeitschrift für Komplementärmedizin · doi:10.1055/a-0591-8783 · Cited by 1
Walker, S. E., Tacinelli, A. M., Wu, H., Pendergraft, S., Horsfall, K., & Dridi, S. (2018) · Advanced in Food Technology and Nutritional Sciences - Open Journal · doi:10.17140/aftnsoj-4-e015 · Cited by 1
Diet and cardiovascular health – What is the data?
Benhayoun, N., Corbasson, I., Karl, M., & Santini, A. (2018) · Annals of Clinical Nutrition · doi:10.33582/2638-1370/1005
RUOLO DEL DIGIUNO E DELLA RESTRIZIONE CALORICA NELLA TERAPIA DEL DIABETE TIPO 2
Cioffi, I., Ponzo, V., & Bo, S. (2018) · il Diabete · doi:10.30682/ildia1804b
Modifiability of Longevity and Quality-of-Life Predictors of Older Adults
Stephens, J., Fiedler, M., Lidell, M., & Gatchel, R. J. (2018) · Handbooks in health, work, and disability · doi:10.1007/978-3-030-03916-5_2
Effektive Gewichtsreduktion bei gynäkologischen Tumorerkrankungen
Paepke, D. (2019) · Der Gynäkologe · doi:10.1007/s00129-019-4460-4
Addressing Obesity in Orthopedics
Aston, B. C. (2019) · JBJS Journal of Orthopaedics for Physician Assistants · doi:10.2106/jbjs.jopa.19.00004
Intermittent fasting and adding more days to life
Mohiuddin, A. K. (2019) · Journal of Drugs and Pharmaceutical Science · doi:10.31248/jdps2019.026
Efeitos do jejum intermitente no peso corporal e perfil lipídico em Rattus norvergicus
Reis, R. D. C., Pinho, T., Rocha, D., de Oliveira, F. L. P., & Sabino, E. (2019) · Journal of Health & Biological Sciences · doi:10.12662/2317-3076jhbs.v7i4.2671.p399-404.2019
Positive impact of intermittent fasting on cardioprotection
Farooq, J., & Ahmed, N. (2019) · eCommons - AKU (Aga Khan University)
Litovka, I. G., Vesselsky, S. P., Magomedov, S., Bogomolets, C. P., Yanko, R. V., & Berezovsky, V. Y. (2020) · Fìzìologìčnij žurnal · doi:10.15407/fz66.01.010
Intermittent Fasting for Treatment of Metabolic Disorders
Itrat, N. (2020) · Emerging contaminants and associated treatment technologies · doi:10.1007/978-3-030-45923-9_26
Verschlackt und übersäuert: Was von Detox-Diäten und Fasten zu halten ist
Bürger, K. (2020) · Springer eBooks · doi:10.1007/978-3-662-61464-8_14
Novel Approaches to Improving Opioid Analgesic Therapy
Duron, D. I. (2020) · UA Campus Repository (The University of Arizona)
Biochemical, Metabolic and Clinical Effects of Intermittent Fasting
Gore, M., Jyothidasan, A., & Nagarajan, V. (2020) · Springer eBooks · doi:10.1007/978-3-030-47336-5_20
Kampet, C., Günzel, S., Hanstein, G., Dimroth, K., Daase, F., Schaepers-Feese, G., Hopfenmüller, W., & Dippel, F. W. (2020) · Ernährung & Medizin · doi:10.1055/a-1115-9709
Reduced ech-6 Expression Attenuates Fat-induced Premature Aging in C. elegansPreprint
Liu, Y. J., Gao, A. W., Smith, R. L., Janssens, G. E., Panneman, D. M., Jongejan, A., van Weeghel, M., Vaz, F. M., Silvestrini, M. J., Lapierre, L. R., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.11.02.364760
From brain to muscle and back : novel approaches to harness the benefits of exercise
Kelahmetoglu, Y. (2020) · Figshare
Yeni Bir Yaklaşım Olan Aralıklı Açlık Yöntemleri ve Sağlık Üzerine Etkileri
Yıldırım, A., & Erge, S. (2020) · Journal of Nutrition and Dietetics · doi:10.33076/2020.bdd.1291
Human survival after age 100: Good luck or good health?Preprint
Álvarez, J.-A., Medford, A., Strozza, C., Thinggaard, M., & Christensen, K. (2021) · Research Square · doi:10.21203/rs.3.rs-219605/v1
Maślanka, R., & Zadrąg‐Tęcza, R. (2021) · Postępy Biochemii · doi:10.18388/pb.2021_369
Intermittent fasting in non-communicable diseases: current evidence
Nolly-Loyaga, A., Perez-Mantilla, S., Aguilar-Ydiáquez, C., Otiniano-Ramos, L. F., Perez-Plasencia, A., Poma-Reyes, I., Aguirre-Flores, R., & Reyes-Beltrán, M. (2021) · Revista Médica de Trujillo · doi:10.17268/rmt.2021.v16i02.10
Updates on mitochondria, calorie restriction, and aging
Yousefsani, B. S., Dadmehr, M., & Pourahmad, J. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-822416-8.00005-1
Modulation of muscle cell insulin receptor signalling, transcription and trafficking by insulin
Cen, H. H. (2021) · cIRcle (University of British Columbia) · doi:10.14288/1.0401784
Talemal, L. (2021) · Journal of Nutritional Medicine and Diet Care · doi:10.23937/2572-3278/1510052
Targeting autophagy: lifestyle and pharmacological approaches
Briones‐Herrera, A., Gómez‐Sierra, T., Martínez‐Klimova, E., Bellido, B., & Pedraza‐Chaverrí, J. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-822003-0.00010-3
Liu, L., Lin, Q.-Z., Zang, X.-Y., Fu, Y. H. H., Wen, X.-Y., & Liu, Q. (2021) · Research Square · doi:10.21203/rs.3.rs-1195738/v1
Saeed, M., & Tian, X. (2021) · Springer eBooks · doi:10.1007/978-3-030-22009-9_1070
Jorge, P. A. M., Martins, J. S. A., de Almeida, J. G., Camilo, N. B., Oliveira, G. R., Gonçalves, L. C., Silva, N. M., da Silva, P. A. N., Passos, X. S., & Bordin, C. C. D. (2022) · Brazilian Journal of Health Review · doi:10.34119/bjhrv5n1-061
JEJUM INTERMITENTE: UMA VISÃO SOBRE A DIABETES E A OBESIDADE
Romero, R. B., Jorge, L. F., Neto, S. A. M., Rocha, C. M., Alvarenga, G. H. F., & Silvério, A. C. P. (2022) · RECIMA21 - Revista Científica Multidisciplinar · doi:10.47820/recima21.v3i2.1096
Myers, T. R., & Goldhamer, A. C. (2020) · Elsevier eBooks · doi:10.1016/b978-0-323-43044-9.00037-6
Dominguez, L. J., & Barbagallo, M. (2022) · Wiley eBooks · doi:10.1002/9781119484288.ch115
Obaideen, K., Shihab, K. A., Madkour, M. I., & Faris, M. E. (2022) · Research Square · doi:10.21203/rs.3.rs-1383372/v1
Oaf, S., Elwakeel, G., Mostafa, A. F., Gad, S., & Mansour, A. (2022) · Egyptian Journal of Chemistry · doi:10.21608/ejchem.2022.118886.5385
Ketogenic Diet and Ketones for Improving Neurologic Outcomes after Acute Neurotrauma
Seira, O., Kolehmainen, K., Plunet, W. T., Yarar‐Fisher, C., & Tetzlaff, W. (2022) · doi:10.1093/med/9780197501207.003.0018
Eating and nutrition links to cancer
Anisman, H., & Kusnecov, A. W. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91904-3.00008-2
Saeed, M., & Tian, X. (2019) · Springer eBooks · doi:10.1007/978-3-319-69892-2_1070-1 · Cited by 1
Systems-wide effects of short-term feed deprivation in obese micePreprint
Andersen, D., Roager, H. M., Zhang, L., Moll, J. M., Frandsen, H. L., Danneskiold‐Samsøe, N. B., Hansen, A. K., Kristiansen, K., Licht, T. R., & Brix, S. (2020) · Research Square · doi:10.21203/rs.3.rs-44356/v1
Obesity Updates: Understanding Obesity as a Disease and Intermittent Fasting
(2021) · The Singapore Family Physician · doi:10.33591/sfp.47.1.u3
Regulatory mechanisms of fasting
Ruppert, P. M. M. (2020) · doi:10.18174/527117
Profile of Ramadhan Fasting Effects On Lipid and Insulin Resistance In Obesity Patients
Lubis, F., Syafril, S., & Lindarto, D. (2021) · International Journal of Scientific and Research Publications · doi:10.29322/ijsrp.11.06.2021.p11455
Seven time-savers for early career researchersPreprint
Ho, T. M. (2020) · OSF Preprints (OSF Preprints) · doi:10.31219/osf.io/79dp8
Fontana, L. (2017) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.732061632.793538504
Seven time-savers for early career researchersPreprint
Ho, T. M. (2020) · OSF Preprints (OSF Preprints) · doi:10.31219/osf.io/cv3mp
Chronic Mechanistic Target of Rapamycin Inhibition: Preventing Cancer to Delay Aging or Vice Versa?
Hambright, H. G., Hurez, V. J., & Curiel, T. J. (2020) · Springer eBooks · doi:10.1007/978-3-319-57415-8_81
Systems-wide effects of short-term feed deprivation in obese micePreprint
Andersen, D., Roager, H. M., Zhang, L., Moll, J. M., Frandsen, H. L., Danneskiold‐Samsøe, N. B., Hansen, A. K., Kristiansen, K., Licht, T. R., & Brix, S. (2020) · Research Square · doi:10.21203/rs.3.rs-44356/v2
López‐Lluch, G., & Navas, P. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.11281-4
Chronic Mechanistic Target of Rapamycin Inhibition: Preventing Cancer to Delay Aging or Vice Versa?
Hambright, H. G., Hurez, V. J., & Curiel, T. J. (2017) · Springer eBooks · doi:10.1007/978-3-319-44870-1_81-1
Chun, L., Pohorielov, O. V., & Бараненко, О. М. (2022) · Medicni perspektivi · doi:10.26641/2307-0404.2022.2.260228
Családi kapcsolatok és evési szokások, zavarok összefüggései
Péczka, A., Tanyi, Z., Kovács, D., Mészáros, V., Jakubovits, E., Szili, I., & Kövi, Z. (2021) · Psychologia Hungarica Caroliensis · doi:10.52993/psyhung.9.2021.1.2
Michael, A., & Baye, K. (2022) · Research Square · doi:10.21203/rs.3.rs-1846637/v1
Overview of various antiaging strategies
Kumar, D., & Ahmad, F. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90235-9.00008-2
Ciric, J., Tešić, V., Milovanovic, N., Macura, I. J., Ivković, S., Kanazir, S., & Perović, M. (2022) · Brain Sciences · doi:10.3390/brainsci12101297
Obesity Updates: Understanding Obesity as Disease and Intermittent Fasting
(2022) · The Singapore Family Physician · doi:10.33591/sfp.48.1.u3
Weight Change Before and After 30 Days of Intermittent Fasting among University Students in Pakistan
Khan, A. A., Qamar, K., Khalid, A., Rashmi, F. N. U., Kumar, A., Nawaz, S. M. A., & Memon, U. (2022) · Journal of Advances in Medicine and Medical Research · doi:10.9734/jammr/2022/v34i224829
Dietary restriction, vegetarian diet, and aging intervention
Suttajit, M., Thangaleela, S., Sivamaruthi, B. S., & Charoensin, S. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90581-7.00023-2 · Cited by 1
Editorial: Mediterranean diet and cancer: Experimental and epidemiological perspectives
Talib, W. H., Waly, M. I., Elkord, E., & Kury, L. T. A. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1064503
Components of an Optimal Weight Loss Diet: What Darwin Would Say About Survival of the Fittest
Bell, S. J., & MacGregor, C. (2022) · Acta Scientifci Nutritional Health · doi:10.31080/asnh.2022.06.1143
The effects of fasting on ischemic infarcts in the ratPreprint
Schneider, A. M., Buchan, A. M., & Couch, Y. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.11.15.516543
Représentations et pratiques du jeûne et des régimes restrictifs pendant la chimiothérapie
Kalecinski, J., Werlen, A.-L., Sene, M.-T., Bertholet, M., Granottier, M., Moundir, K., Salque, C., Vazille, C., Brosse, C., Langlet, H., et al. (2022) · Santé Publique · doi:10.3917/spub.224.0481
Impactos do Jejum Intermitente na perda de peso
Torres, M. T., Martins, E. C. B., Pereira, L. N. J., & Kury, C. M. H. (2022) · Revista Científica da Faculdade de Medicina de Campos · doi:10.29184/1980-7813.rcfmc.542.vol.17.n2.2022
Moderne Therapieformen der Adipositas
Rabast, U. (2022) · Springer eBooks · doi:10.1007/978-3-662-65230-5_17
The Potential Benefits of Fasting Do Not Include Regenerative Stem Cells
Nimmons, A., & Gallicchio, V. S. (2022) · Journal of Medical - Clinical Research & Reviews · doi:10.33425/2639-944x.1303
Schoonakker, M. P., van den Burg, E. L., van Peet, P. G., Lamb, H. J., Numans, M. E., & Pijl, H. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-822186-0.00025-0 · Cited by 1
O QUE O JEJUM INTERMITENTE TEM A DIZER SOBRE CÂNCER, SAÚDE CARDIOVASCULAR E SAÚDE CÉREBRO-MENTAL
Romero, R. B., Rocha, C. M., Neto, S. A. M., Alvarenga, G. H. F., Cruz, R. B., Jorge, L. F., & Silvério, A. C. P. (2023) · RECIMA21 - Revista Científica Multidisciplinar · doi:10.47820/recima21.v4i1.2638
Beslenmede Metilasyon Döngüsü Kavramı ve Hastalık İlişkileri
Yıldırım, Z., & Küçükkendirci, H. (2023) · Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi · doi:10.46237/amusbfd.1039164
The Effect Of Functional Training And Intermittent Fasting One Some Body Components For Women
Mohamed, S., Mohamed, M., & Talaat, D. (2022) · International Journal of Sports Science and Arts · doi:10.21608/eijssa.2022.146804.1166
Effect of Prolonged Fasting on Uric Acid Metabolism and Its Regulation Mechanism
Sui, X., Zhifeng, G. U. O., Zhang, H., Wang, H., Wu, F., Yang, C., Guo, Y., Ting, M. A., Li, Y., & Dai, Z. (2023) · Chinese Journal of Space Science · doi:10.11728/cjss2023.01.220225021
The Impact of the Hypercaloric Diet versus the Mediterranean Diet on Insulin Sensitivity
Radu, F. I., Ranetti, A.-E., Vasile, M., Sirbu, A. M., Axelerad, A. D., & Sîrbu, C. A. (2023) · Romanian Journal of Military Medicine · doi:10.55453/rjmm.2023.126.3.6 · Cited by 1
Lewis, S. A., Britt, W. M., Koch, R. L., Razavi, A. C., Patel, P., Sperling, L. S., & Souza, M. S. D. (2023) · The Journal of Cardiovascular Aging · doi:10.20517/jca.2023.1 · Cited by 1
Effect of Prolonged Fasting on Uric Acid Metabolism and Its Regulation Mechanism
Sui, X., Zhifeng, G. U. O., Zhang, H., Wang, H., Wu, F., Yang, C., Guo, Y., Ting, M. A., Li, Y., & Dai, Z. (2023) · Chinese Journal of Space Science · doi:10.11728/cjss2023.02.220225021
Aortic Regeneration is Promoted by Intermittent Fasting in Aged Rats
Teker, H. T., & Ceylani, T. (2023) · Sakarya University Journal of Science · doi:10.16984/saufenbilder.1209954
Wang, Y. (2023) · Theoretical and Natural Science · doi:10.54254/2753-8818/4/20220509
Lubczyńska, Z., POPRAVKO, Y., Lewandowski, M. M., Bienia, G., ŻOŁNIEREK, M., ŚWIĘTOCHOWSKI, J., SIEKIERKO, N., KOTUSIEWICZ, W., Jędrzejewska, B., & Kotulska, M. (2023) · Journal of Education Health and Sport · doi:10.12775/jehs.2023.38.01.005 · Cited by 1
Peinado, J. (2022) · Digital Commons - Andrews University (Andrews University) · doi:10.32597/dmin/760/
ESTRATÉGIAS DE PROMOÇÃO DE SAÚDE BUCAL EM GESTANTES: REVISÃO DE LITERATURA
Duarte, A. V. M., de Carvalho, H. M. A., Alves, I. P. D. C., Borges, J. M. D. S., Lopes, K. F. D. S., de Freitas, K. N., Honorato, L. B., da Silva, L. D. C. P., Cavalcante, M. R. D. S., & Vieira, F. C. R. (2023) · Paulo Sérgio da Paz Silva Filho eBooks · doi:10.56161/sci.ed.20230527c13
CUIDADO FARMACÊUTICO RELACIONADO A SUPLEMENTOS ALIMENTARES
Mouzinho, C. P. B., Santos, C. A., Lemos, M. F. R. P., & de Queiroz, M. D. S. R. (2023) · Paulo Sérgio da Paz Silva Filho eBooks · doi:10.56161/sci.ed.20230527c11
CUIDADO FARMACÊUTICO NO ATENDIMENTO DA PESSOA COM OBESIDADE
Lima, A. H., Guimarães, A. M. P. L., Pereira, C. S., Silva, J. A. D. S., Carvalho, L. S., Andrade, M., de Azevedo, T. M., dos Santos, V. M., & de Queiroz, M. D. S. R. (2023) · Paulo Sérgio da Paz Silva Filho eBooks · doi:10.56161/sci.ed.20230527c10
AGRESSÕES NA INFÂNCIA E OS POSSÍVEIS IMPACTOS PSICOLÓGICOS: UMA REVISÃO INTEGRATIVA
Neto, I. B., Pereira, A. V., de Medeiros, A. L. G., de Souza, C. W. N., & Reinaldo, M. L. (2023) · Paulo Sérgio da Paz Silva Filho eBooks · doi:10.56161/sci.ed.20230527c4
ALEITAMENTO MATERNO NA UNIDADE DE TERAPIA INTENSIVA NEONATAL: REVISÃO DE LITERATURA
do Nascimento, B. T. S., Frese, B., Ferreira, G. S., Rabelo, N. N. D. F., Domingos, T. M. R., Rodrigues, R. D. D. S., da Silva, M. H. N., Ferreira, L. F., da Silva, J. M., & do Nascimento, I. T. S. (2023) · Paulo Sérgio da Paz Silva Filho eBooks · doi:10.56161/sci.ed.20230527c5
Metadata
- Authors
- Mattson, M. P., Longo, V. D., & Harvie, M.
- Affiliations
- Johns Hopkins University (US)
- University of Southern California (US)
- Wythenshawe Hospital (GB)
- Corresponding author
- Mattson, Mark P.
- Venue
- Ageing Research Reviews
- Publisher
- Elsevier BV
- Published
- 2017-10
- Volume
- 39
- Pages
- 46-58
- ISSN
- 1568-1637 (ISSN-L)
- PMC
- PMC5411330
- OpenAlex
- W2542468576
- Semantic Scholar
- 9368e04d8de55f82fdeabf816d930cd45e879039
- Cited by
- 1,187
- References
- 142
- Citations by year
- 2026: 89 · 2025: 154 · 2024: 152 · 2023: 141 · 2022: 155 · 2021: 175 · 2020: 121 · 2019: 92 · 2018: 69 · 2017: 39
- FWCI
- 7.83
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Ageing Research Reviews (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Institute on Aging (ZIAAG000331, ZIAAG000315, ZIAAG000317)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Dietary Effects on Health
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
- Health Sciences › Medicine › Geriatrics and Gerontology › Sirtuins and Resveratrol in Medicine
- Keywords
- intermittent fasting, fasting-mimicking diet, time-restricted feeding, caloric restriction, insulin resistance, metabolic disorders, aging, autophagy, mitochondrial health, DNA repair, stem cell regeneration, weight loss, cardiovascular disease, diabetes mellitus, neurodegenerative diseases, cancer, cellular stress response
- MeSH terms
- Healthy Aging, Animals, Energy Intake, Cardiovascular Diseases, Chronic Disease, Diet, Eating, Fasting, Feeding Behavior, Humans, Insulin Resistance, Obesity, Weight Loss, Caloric Restriction
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
