Longo, Valter D.

Extending Healthy Life Span—From Yeast to Humans

Fontana, L., Partridge, L., & Longo, V. D. (2010) · Science

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 3,023

Fasting: molecular mechanisms and clinical applications

Longo, V. D., & Mattson, M. P. (2014) · Cell Metabolism

Dietary Effects on HealthGenetics, Aging, and Longevity in Model Organisms

Cited by 1,425

Impact of intermittent fasting on health and disease processes

Mattson, M. P., Longo, V. D., & Harvie, M. (2017) · Ageing Research Reviews

Dietary Effects on HealthGenetics, Aging, and Longevity in Model Organisms

Cited by 1,187

Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan

Longo, V. D., & Panda, S. (2016) · Cell Metabolism

Dietary Effects on HealthGenetics, Aging, and Longevity in Model Organisms

Cited by 1,013

Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population

Levine, M. E., Suarez, J. A., Brandhorst, S., Balasubramanian, P., Cheng, C.-W., Madia, F., Fontana, L., Mirisola, M. G., Guevara-Aguirre, J., Wan, J., et al. (2014) · Cell Metabolism

Dietary Effects on HealthGenetics, Aging, and Longevity in Model Organisms

Cited by 910

A periodic diet that mimics fasting promotes multi-system regeneration, enhanced cognitive performance, and healthspan

Brandhorst, S., Choi, I. Y., Wei, M., Cheng, C. W., Sedrakyan, S., Navarrete, G., Dubeau, L., Yap, L. P., Park, R., Vinciguerra, M., et al. (2015) · Cell Metabolism

Dietary Effects on HealthGenetics, Aging, and Longevity in Model Organisms

Cited by 850

Association of animal and plant protein intake with all-cause and cause-specific mortality.

Song, M., Fung, T. T., Hu, F. B., Willett, W. C., Longo, V. D., Chan, A. T., & Giovannucci, E. L. (2016) · JAMA Internal Medicine

Nutritional Studies and DietAgriculture Sustainability and Environmental Impact

Cited by 735

Sirtuins in aging and age-related disease

Longo, V. D., & Kennedy, B. K. (2006) · Cell

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 628

Replicative and chronological aging in Saccharomyces cerevisiae

Longo, V. D., Shadel, G. S., Kaeberlein, M., & Kennedy, B. (2012) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 595

Interventions to slow aging in humans: are we ready?

Longo, V. D., Antebi, A., Bartke, A., Barzilai, N., Brown‐Borg, H. M., Caruso, C., Curiel, T. J., Cabo, R., Franceschi, C., Gems, D., et al. (2015) · Aging Cell

Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine

Cited by 592

Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy.

Raffaghello, L., Lee, C., Safdie, F. M., Wei, M., Madia, F., Bianchi, G., & Longo, V. D. (2008) · Proceedings of the National Academy of Sciences

Cell death mechanisms and regulationRedox biology and oxidative stress

Cited by 587

Evolutionary medicine: from dwarf model systems to healthy centenarians?

Longo, V. D., & Finch, C. E. (2003) · Science

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 575

Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease

Wei, M., Brandhorst, S., Shelehchi, M., Mirzaei, H., Cheng, C. W., Budniak, J., Groshen, S., Mack, W. J., Guen, E., Di Biase, S., et al. (2017) · Science Translational Medicine

Dietary Effects on HealthGenetics, Aging, and Longevity in Model Organisms

Cited by 553

SIRT1 Is Essential for Normal Cognitive Function and Synaptic Plasticity

Michan, S., Li, Y., Chou, M. M.-H., Parrella, E., Ge, H., Long, J. M., Allard, J. S., Lewis, K., Miller, M., Xu, W., et al. (2010) · Journal of Neuroscience

Sirtuins and Resveratrol in MedicineNeuroscience and Neuropharmacology Research

Cited by 541

Fasting and cancer: molecular mechanisms and clinical application

Nencioni, A., Caffa, I., Cortellino, S., & Longo, V. D. (2018) · Nature Reviews Cancer

Dietary Effects on HealthCancer, Lipids, and Metabolism

Cited by 518

Calorie restriction and cancer prevention: metabolic and molecular mechanisms

Longo, V. D., & Fontana, L. (2010) · Trends in Pharmacological Sciences

Dietary Effects on HealthGenetics, Aging, and Longevity in Model Organisms

Cited by 378

Superoxide is a mediator of an altruistic aging program in Saccharomyces cerevisiae

Fabrizio, P., Battistella, L., Vardavas, R., Gattazzo, C., Liou, L.-L., Diaspro, A., Dossen, J. W., Gralla, E. B., & Longo, V. D. (2004) · The Journal of Cell Biology

Genetics, Aging, and Longevity in Model OrganismsEvolution and Genetic Dynamics

Cited by 355

SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons

Li, Y., Xu, W., McBurney, M. W., & Longo, V. D. (2008) · Cell Metabolism

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 331

Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology

Rangan, P., Choi, I., Wei, M., Navarrete, G., Guen, E., Brandhorst, S., Enyati, N., Pasia, G., Maesincee, D., Ocon, V., et al. (2019) · Cell Reports

Inflammatory Bowel DiseaseDietary Effects on Health

Cited by 312

Peroxynitrite Mediates Neurotoxicity of Amyloid β-Peptide 1–42 - and Lipopolysaccharide-Activated Microglia

Xie, Z., Wei, M., Morgan, T. E., Fabrizio, P., Han, D., Finch, C. E., & Longo, V. D. (2002) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 272

Targeting Cancer Metabolism: Dietary and Pharmacologic Interventions

Vernieri, C., Casola, S., Foiani, M., Pietrantonio, F., de Braud, F., & Longo, V. (2016) · Cancer Discovery

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 202

Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models

Bianchi, G., Martella, R., Ravera, S., Marini, C., Capitanio, S., Orengo, A., Emionite, L., Lavarello, C., Amaro, A., Petretto, A., et al. (2015) · Oncotarget

Dietary Effects on HealthCancer, Hypoxia, and Metabolism

Cited by 173

Starvation, Stress Resistance, and Cancer

Buono, R., & Longo, V. D. (2018) · Trends in Endocrinology & Metabolism

Dietary Effects on HealthMetabolism, Diabetes, and Cancer

Cited by 162

Fasting-mimicking diet blocks triple-negative breast cancer and cancer stem cell escape

Salvadori, G., Zanardi, F., Iannelli, F., Lobefaro, R., Vernieri, C., & Longo, V. D. (2021) · Cell Metabolism

Dietary Effects on HealthCancer, Hypoxia, and Metabolism

Cited by 159