C-reactive protein and alcohol consumption: Is there a U-shaped association? Results from a population-based study in Russia

Averina, Maria; Nilssen, Odd; Arkhipovsky, V.L.; Kalinin, A.G.; Brox, Jan

doi:10.1016/j.atherosclerosis.2005.11.007

Cited by 24Alcohol Consumption and Health EffectsSubstance Abuse Treatment and OutcomesAdipokines, Inflammation, and Metabolic Diseases

C-reactive protein and alcohol consumption: Is there a U-shaped association? Results from a population-based study in Russia

Averina, Maria, Nilssen, Odd, Arkhipovsky, V.L., Kalinin, A.G., Brox, Jan·2006·Atherosclerosis

DOI 10.1016/j.atherosclerosis.2005.11.007

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Abstract

Background Little is known about association between markers of inflammation and alcohol consumption in Russian population where binge drinking pattern is prevalent.Methods and results C-reactive protein was measured by a highly sensitive particle-enhanced immunoturbidimetric assay (hsCRP) in 1963 men and 1734 women, aged 18-90 years, in a population-based cross-sectional study. Total alcohol consumption consisted mainly of binge vodka intake. A revealed U-shaped association between hsCRP and total alcohol intake was due to high hsCRP levels in ex-drinkers. Ex-drinkers of both sexes were older and reported more diseases than non-abstainers. This U-shaped association became non-significant in both sexes after adjustment for age, BMI, smoking status, diabetes mellitus and cardiovascular medication. When analysis was performed separately only for non-abstainers, hsCRP showed a positive linear association with total weekly alcohol consumption and with weekly vodka consumption in both sexes.Conclusions The U-shaped association between hsCRP and weekly alcohol consumption was due to higher hsCRP levels in ex-drinkers than in non-abstainers. Factors other than the current level of alcohol consumption might be responsible for high hsCRP levels in ex-drinkers. When abstainers were excluded from analyses, the results indicated a pro-inflammatory effect of binge alcohol consumption in non-abstainers.

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C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women
Ridker, P. M., Hennekens, C. H., Buring, J. E., & Rifai, N. (2000) · New England Journal of Medicine · doi:10.1056/nejm200003233421202 · Cited by 5,850 · see citing works
Comparison of C-Reactive Protein and Low-Density Lipoprotein Cholesterol Levels in the Prediction of First Cardiovascular Events
Ridker, P. M., Rifai, N., Rose, L., Buring, J. E., & Cook, N. R. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa021993 · Cited by 3,604 · see citing works
C-Reactive Protein, a Sensitive Marker of Inflammation, Predicts Future Risk of Coronary Heart Disease in Initially Healthy Middle-Aged Men
Köenig, W., Sund, M., Fröhlich, M., Fischer, H.-G., Löwel, H., Döring, A., Hutchinson, W. L., & Pepys, M. B. (1999) · Circulation · doi:10.1161/01.cir.99.2.237 · Cited by 1,952 · see citing works
Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine
Frankel, E. N., German, J. B., Kinsella, J. E., Parks, E. J., & Kanner, J. (1993) · The Lancet · doi:10.1016/0140-6736(93)90206-v · Cited by 1,646 · see citing works
Plasma Concentration of C-Reactive Protein and Risk of Ischemic Stroke and Transient Ischemic Attack: The Framingham Study
Rost, N. S., Wolf, P. A., Kase, C. S., Kelly‐Hayes, M., Silbershatz, H., Massaro, J. M., D’Agostino, R. B., Franzblau, C., & Wilson, P. W. F. (2001) · Stroke · doi:10.1161/hs1101.098151 · Cited by 799 · see citing works
Effect of alcohol consumption on systemic markers of inflammation
Imhof, A., Froehlich, M., Brenner, H., Boeing, H., Pepys, M. B., & Koenig, W. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04170-2 · Cited by 559 · see citing works
Prospective Study of C-Reactive Protein, Homocysteine, and Plasma Lipid Levels as Predictors of Sudden Cardiac Death
Albert, C. M., Ma, J., Rifai, N., Stampfer, M. J., & Ridker, P. M. (2002) · Circulation · doi:10.1161/01.cir.0000017493.03108.1c · Cited by 532 · see citing works
Comparison of C-Reactive Protein and Low-Density Lipoprotein Cholesterol Levels in the Prediction of First Cardiovascular Events
Ridker, P. M., Rifai, N., Rose, L. M., Buring, J. E., & Cook, N. R. (2003) · Obstetrical & Gynecological Survey · doi:10.1097/01.ogx.0000058687.18516.14 · Cited by 390 · see citing works
Alcohol Consumption and Plasma Concentration of C-Reactive Protein
Albert, M. A., Glynn, R. J., & Ridker, P. M. (2003) · Circulation · doi:10.1161/01.cir.0000045669.16499.ec · Cited by 325 · see citing works
Beer binging and mortality: results from the kuopio ischaemic heart disease risk factor study, a prospective population based study
Kauhanen, J., Kaplan, G. A., Goldberg, D. E., & Salonen, J. T. (1997) · BMJ · doi:10.1136/bmj.315.7112.846 · Cited by 278 · see citing works
Different effects of red wine and gin consumption on inflammatory biomarkers of atherosclerosis: a prospective randomized crossover trial
Estruch, R., Sacanella, E., Badı́a, E., Antúnez, E., Nicolas, J. M., Fernández‐Solà, J., Rotilio, D., de Gaetano, G., Rubin, E., & Urbano-Márquez, A. (2004) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2004.03.006 · Cited by 269 · see citing works
Alcohol Volume, Drinking Pattern, and Cardiovascular Disease Morbidity and Mortality: Is There a U-shaped Function?
Murray, R. P., Connett, J. E., Tyas, S. L., Bond, R., Ekuma, O., Silversides, C. K., & Barnes, G. E. (2002) · American Journal of Epidemiology · doi:10.1093/aje/155.3.242 · Cited by 266 · see citing works
Alcohol consumption in a national sample of the Russian population
Bobák, M., McKee, M., Rose, R., & Marmot, M. G. (1999) · Addiction · doi:10.1046/j.1360-0443.1999.9468579.x · Cited by 229 · see citing works
Overall alcohol intake, beer, wine, and systemic markers of inflammation in western Europe: results from three MONICA samples (Augsburg, Glasgow, Lille)
IMHOF, A., WOODWARD, M., DOERING, A., HELBECQUE, N., LOEWEL, H., AMOUYEL, P., LOWE, G., & KOENIG, W. (2004) · European Heart Journal · doi:10.1016/j.ehj.2004.09.032 · Cited by 204 · see citing works
Relationship of Alcohol Intake With Inflammatory Markers and Plasminogen Activator Inhibitior-1 in Well-Functioning Older Adults: The Health, Aging, and Body Composition Study
Volpato, S., Pahor, M., Ferrucci, L., Simonsick, E. M., Guralnik, J. M., Kritchevsky, S. B., Fellin, R., & Harris, T. B. (2004) · Circulation · doi:10.1161/01.cir.0000109503.13955.00 · Cited by 176 · see citing works
Development of a new microparticle-enhanced turbidimetric assay for C-reactive protein with superior features in analytical sensitivity and dynamic range
Eda, S., Kaufmann, J., Roos, W., & Pohl, S. (1998) · Journal of Clinical Laboratory Analysis · doi:10.1002/(sici)1098-2825(1998)12:3 · Cited by 162 · see citing works
Alcohol is Implicated in the Fluctuations in Cardiovascular Disease in Russia Since the 1980s
McKee, M., Школьников, В. М., & Leon, D. A. (2001) · Annals of Epidemiology · doi:10.1016/s1047-2797(00)00080-6 · Cited by 124 · see citing works
Development and validation of a particle-enhanced turbidimetric immunoassay for C-reactive protein
Price, C. P., Trull, A. K., Berry, D., & Gorman, E. G. (1987) · Journal of Immunological Methods · doi:10.1016/0022-1759(87)90129-3 · Cited by 124 · see citing works
Increased mortality related to heavy alcohol intake pattern
Laatikainen, T. K., Manninen, L., Poikolainen, K., & Vartiainen, E. (2003) · Journal of Epidemiology & Community Health · doi:10.1136/jech.57.5.379 · Cited by 116 · see citing works
Ethanol and Oxidative Stress
Sun, A. Y., Ingelman‐Sundberg, M., Neve, E. P. A., Matsumoto, H., Nishitani, Y., Minowa, Y., Fukui, Y., Bailey, S. M., Patel, V. B., CUNNINGHAM, C. C., et al. (2001) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2001.tb02402.x · Cited by 104 · see citing works
Ethanol and Oxidative Stress
Sun, A. Y., Ingelman‐Sundberg, M., Neve, E. P. A., Matsumoto, H., Nishitani, Y., Minowa, Y., Fukui, Y., Bailey, S. M., Patel, V. B., CUNNINGHAM, C. C., et al. (2001) · Alcoholism Clinical and Experimental Research · doi:10.1097/00000374-200105051-00038 · Cited by 100 · see citing works
The effects of different alcoholic drinks on lipids, insulin and haemostatic and inflammatory markers in older men
Lowe, G. D. O., Shaper, G., Whincup, P. H., Rumley, A., Walker, M., LENNON, L. T., & Wannamethee, S. G. (2003) · Thrombosis and Haemostasis · doi:10.1160/th03-04-0221 · Cited by 80 · see citing works
Cardiovascular risk factors in the former communist countries
GINTER, E. (1995) · European Journal of Epidemiology · doi:10.1007/bf01719488 · Cited by 77 · see citing works
Relation between alcohol consumption and C-reactive protein levels in the adult US population.
Stewart, S., Mainous, A. G., & Gilbert, G. E. (2002) · PubMed · Cited by 63 · see citing works
ADVANCED GLYCATION END-PRODUCTS IN PATIENTS WITH CHRONIC ALCOHOL MISUSE
Marta, K. (2004) · Alcohol and Alcoholism · doi:10.1093/alcalc/agh058 · Cited by 53 · see citing works
Association of high-density-lipoprotein cholesterol with mortality and other risk factors for major chronic noncommunicable diseases in samples of US and Russian men
Nv, P., Оганов, Р. Г., Williams, D. H., Irving, S. H., Abernathy, J. R., Деев, А. Д., Шестов, Д. Б., Zhukovsky, G., DAVIS, C. E., & Tyroler, H. A. (1995) · Annals of Epidemiology · doi:10.1016/1047-2797(94)00104-2 · Cited by 47 · see citing works
High cardiovascular mortality in Russia cannot be explained by the classical risk factors. The Arkhangelsk study 2000
Averina, M., Nilssen, O., Brenn, T., Brox, J. H., Kalinin, A. G., & Arkhipovsky, V. L. (2003) · European Journal of Epidemiology · doi:10.1023/a:1025626202235 · Cited by 46 · see citing works
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ALCOHOL MISUSE INCREASES SERUM ANTIBODIES TO OXIDIZED LDL AND C-REACTIVE PROTEIN
Alho, H. (2004) · Alcohol and Alcoholism · doi:10.1093/alcalc/agh059 · Cited by 38 · see citing works
Anti-oxidized LDL Antibodies and Wine Consumption
Bari, M. D., Zacchei, S., Kritchevsky, S. B., Anichini, M., Cesaretti, S., Chiarlone, M., Masotti, G., & Marchionni, N. (2003) · Annals of Epidemiology · doi:10.1016/s1047-2797(02)00262-4 · Cited by 12 · see citing works
The effects of different alcoholic drinks on haemostatic and inflammatory markers, lipids and insulin in older men: British Regional Heart Study
Lowe, G. D. O., Wannamethee, S. G., Shaper, A. G., Whincup, P. H., Rumley, A., Walker, M., & LENNON, L. T. (2003) · UCL Discovery (University College London) · Cited by 4 · see citing works

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Dietary factors and low-grade inflammation in relation to overweight and obesity
Calder, P. C., Ahluwalia, N., Brouns, F., Buetler, T., Clement, K., Cunningham, K., Esposito, K., Jönsson, L. S., Kolb, H., Lansink, M., et al. (2011) · British Journal of Nutrition · doi:10.1017/s0007114511005460 · Cited by 1,098 · see citing works
Fruit Polyphenols: A Review of Anti-inflammatory Effects in Humans
Joseph, S. V., Edirisinghe, I., & Burton‐Freeman, B. M. (2015) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2013.767221 · Cited by 282 · see citing works
“Binge drinking of alcohol has been associated with increased systemic inflammation and cardiovascular morbidity (de Lange et al., 2004; Averina et al., 2006).”
Background
Exposure-dependent effects of ethanol on the innate immune system
Goral, J., Karavitis, J., & Kovacs, E. J. (2008) · Alcohol · doi:10.1016/j.alcohol.2008.02.003 · Cited by 152 · see citing works
Alcohol consumption: Risks and benefits
Mukamal, K. J., & Rimm, E. B. (2008) · Current Atherosclerosis Reports · doi:10.1007/s11883-008-0083-2 · Cited by 109 · see citing works
“When assessed across a broad spectrum of alcohol intake, the general relationship is a U-shaped association for most markers of infl ammation [16].”
Background
High Sensitivity C-reactive Protein (hsCRP) and its Implications in Cardiovascular Outcomes
Denegri, A., & Boriani, G. (2020) · Current Pharmaceutical Design · doi:10.2174/1381612826666200717090334 · Cited by 92 · see citing works
Prevalence of the metabolic syndrome and its components in Northwest Russia: the Arkhangelsk study
Sidorenkov, O., Nilssen, O., Brenn, T., Martiushov, S., Arkhipovsky, V. L., & Grjibovski, A. M. (2010) · BMC Public Health · doi:10.1186/1471-2458-10-23 · Cited by 70 · see citing works
“More details about the study, recruitment details, sample and data collection protocols are presented elsewhere [21, 22 ].”
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Association between Combined Lifestyle Factors and Non-Restorative Sleep in Japan: A Cross-Sectional Study Based on a Japanese Health Database
Wakasugi, M., Kazama, J. J., Narita, I., Iseki, K., Moriyama, T., Yamagata, K., Fujimoto, S., Tsuruya, K., Asahi, K., Konta, T., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0108718 · Cited by 65 · see citing works
Socioeconomic position, health behaviors, and C-reactive protein: A moderated-mediation analysis.
Kershaw, K. N., Mezuk, B. R., Abdou, C. M., Rafferty, J. A., & Jackson, J. S. (2010) · Health Psychology · doi:10.1037/a0019286 · Cited by 62 · see citing works
Evidence for a Direct Harmful Effect of Alcohol on Myocardial Health: A Large Cross‐Sectional Study of Consumption Patterns and Cardiovascular Disease Risk Biomarkers From Northwest Russia, 2015 to 2017
Iakunchykova, O. P., Averina, M., Kudryavtsev, A. V., Wilsgaard, T., Soloviev, A. G., Schirmer, H., Cook, S., & Leon, D. A. (2019) · Journal of the American Heart Association · doi:10.1161/jaha.119.014491 · Cited by 31 · see citing works
Self-citation
Why does Russia have such high cardiovascular mortality rates? Comparisons of blood-based biomarkers with Norway implicate non-ischaemic cardiac damage
Iakunchykova, O. P., Averina, M., Wilsgaard, T., Watkins, H. C., Malyutina, S. K., Ragino, Y. I., Keogh, R. H., Kudryavtsev, A. V., Govorun, V. M., Cook, S., et al. (2020) · Journal of Epidemiology & Community Health · doi:10.1136/jech-2020-213885 · Cited by 21 · see citing works
Self-citation
Premature cardiovascular mortality and alcohol consumption before death in Arkhangelsk, Russia: an analysis of a consecutive series of forensic autopsies
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Associations of cigarette smoking, betel quid chewing and alcohol consumption with high-sensitivity C-reactive protein in early radiographic knee osteoarthritis: a cross-sectional study
Zhang, Y., Zeng, C., Wei, J., Li, H., Yang, T., Yang, Y., Deng, Z., Ding, X., & Lei, G. (2016) · BMJ Open · doi:10.1136/bmjopen-2015-010763 · Cited by 13 · see citing works
The Significant Role of Alcohol in the Relationship between C-Reactive Protein and Self-Reported Osteoarthritis
He, K., & Huang, H. (2024) · Journal of Nutrition · doi:10.1016/j.tjnut.2024.01.009 · Cited by 9 · see citing works
Dietary calcium intake is associated with serum high-sensitivity C-reactive protein level in the general Japanese population
Katsuura‐Kamano, S., Uemura, H., Yamaguchi, M., Nakamoto, M., Bahari, T., Miki, K., Ishizu, M., Sawachika, F., & Arisawa, K. (2017) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.17-48 · Cited by 8 · see citing works
Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population
Алексеевна, М. О., Kholmatova, K., Постоева, А. В., Николаевна, К. Г., Malyutina, S. K., & Kudryavtsev, A. V. (2023) · Biomolecules · doi:10.3390/biom13050835 · Cited by 5 · see citing works
Alcohol consumption and heart failure: a dose-response meta-analysis
Wong, B., Ryan, C. A., Fagbamigbe, A. F., Bray, J. J. H., McNamee, B., Niranjan, V. R., Zhou, S., Bogdanet, D., Reddin, C., McDonald, K., et al. (2024) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd015398 · Cited by 3 · see citing works
Alcohol consumption and binge drinking as risk factors for cardiovascular diseases and depression
Sundell, L. (2010) · STM:n Hallinnonalan avoin julkaisuarkisto (Julkari) · Cited by 3 · see citing works
Relationship between hs-CRP and cardiac efficiency in chronic alcoholics
Latha, R., & Shenoy, K. C. (2008) · Indian Journal of Clinical Biochemistry · doi:10.1007/s12291-008-0063-x · Cited by 2 · see citing works
“The U-shaped association between hs-CRP and alcohol consumption has been reported from studies conducted in Russia ( 14 ).”
The Longitudinal Relationship between Moderate Alcohol Use and Cognitive Aging among Older Adults.
Herring, D. (2016) · Journal of International Crisis and Risk Communication Research · Cited by 2 · see citing works
С-reactive Protein and Its Role in Pathogenesis of Heart Disorders (Literature Review and Own Data)
Strilchuk, L. M. (2019) · Family Medicine · doi:10.30841/2307-5112.2.2019.175680 · Cited by 1 · see citing works
A study of effect of alcohol consumption on cardiovascular biomarkers in a tertiary care centre in the Kumaon Region
Shukla, D. P., Joshi, B., Singh, S., & Kumar, A. (2022) · Panacea Journal of Medical Sciences · doi:10.18231/j.pjms.2022.097
Association of alcohol consumption with circulating biomarkers of atrial fibrillation-related pathways in a population at high cardiometabolic risk
Alam, A. B., Toledo, E., Romaguera, D., Alonso‐Gómez, Á. M., Martínez‐González, M. Á., Tojal‐Sierra, L., Razquín, C., Mora, M. N., Li, L., Subramanya, V., et al. (2026) · British Journal Of Nutrition · doi:10.1017/s0007114526107922
Prevalence of alcohol use disorder and its association with disease severity in symptomatic peripheral arterial disease
Biscetti, F., Rando, M. M., Danese, M., Nicolazzi, M. A., Massetti, M., Gasbarrini, A., Addolorato, G., & Flex, A. (2026) · Scientific Reports · doi:10.1038/s41598-026-44431-6
Alcohol Consumption and Cardiovascular and All-Cause Mortality in Poland and the Wider Central and Eastern European Region: A Scoping Review
Sendrowski, D., Sendrowska, M. K., & Kozłowski, D. (2026) · Sci · doi:10.3390/sci8090221

Effect of alcohol consumption on systemic markers of inflammation
Imhof, A., Froehlich, M., Brenner, H., Boeing, H., Pepys, M. B., & Koenig, W. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04170-2 · Cited by 559 · see citing works
Long-term and short-term alcohol consumption and levels of C-reactive protein
Raum, E., Gebhardt, K., Buchner, M., Schiltenwolf, M., & Brenner, H. (2006) · International Journal of Cardiology · doi:10.1016/j.ijcard.2006.08.104 · Cited by 25 · see citing works
Relation between alcohol consumption and C-reactive protein levels in the adult US population.
Stewart, S., Mainous, A. G., & Gilbert, G. E. (2002) · PubMed · Cited by 63 · see citing works
Alcohol Consumption and Plasma Concentration of C-Reactive Protein
Albert, M. A., Glynn, R. J., & Ridker, P. M. (2003) · Circulation · doi:10.1161/01.cir.0000045669.16499.ec · Cited by 325 · see citing works
ORIGINAL ARTICLES Relation Between Alcohol Consumption and C- Reactive Protein Levels in the Adult US Population
Stewart, S. H., Mainous, A. G., & Gilbert, G. (2015)

Authors: Averina, M., Nilssen, O., Arkhipovsky, V. L., Kalinin, A. G., & Brox, J.
Affiliations: UiT The Arctic University of Norway (NO)
Central Clinical Hospital No 2 named Semashko (RU)
Northern State Medical University (RU)
University Hospital of North Norway (NO)
Corresponding author: Averina, Maria
ORCID: Averina, Maria
Kalinin, A.G.
Brox, Jan
Venue: Atherosclerosis
Publisher: Elsevier BV
Published: 2006-10
Volume: 188
Issue: 2
Pages: 309-315
ISSN: 0021-9150 (ISSN-L)
DOI: 10.1016/j.atherosclerosis.2005.11.007
OpenAlex: W127986995
Cited by: 24
References: 30
Citations by year: 2026: 3 · 2024: 2 · 2023: 1 · 2022: 1 · 2020: 2 · 2019: 2 · 2017: 1 · 2016: 2 · 2015: 1 · 2014: 1
FWCI: 0.67
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Atherosclerosis (publishedVersion)
PubMed (publishedVersion)
Funders: Norges Forskningsråd
Topics: Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
Keywords: C-reactive protein, alcohol consumption, binge drinking, vodka, inflammation, ex-drinkers, alcohol abstinence, U-shaped relationship, Russian population
MeSH terms: Adolescent, Adult, Age Factors, Alcohol Drinking, C-Reactive Protein, Female, Humans, Male, Middle Aged, Nephelometry and Turbidimetry, Russia, Smoking, Body Mass Index

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C-reactive protein and alcohol consumption: Is there a U-shaped association? Results from a population-based study in Russia

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