Cited by 219Diet and metabolism studiesDietary Effects on HealthNutritional Studies and Diet

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The ketogenic diet: Pros and cons

O'Neill, Blair, Raggi, Paolo·2020·Atherosclerosis

DOI 10.1016/j.atherosclerosis.2019.11.021

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Abstract

Diets have been at the center of animated debates for decades and many claims have been made in one direction or the other by supporters of opposite camps, often with limited evidence. At times emphasis has been put on a single new aspect that the previous diets had overlooked and the new one was to embrace in order to improve weight loss and well-being. Unfortunately, very few randomized clinical trials involving diets have addressed the combined question of weight loss and cardiovascular outcomes. The recently introduced ketogenic diet requires a rigorous limitation of carbohydrates while allowing a liberal ingestion of fats (including saturated fats) and has generated a flurry of interest with many taking the pro position and as many taking the cons position. The ketogenic diet causes a rapid and sensible weight loss along with favourable biomarker changes, such as a reduction in serum hemoglobin A1c in patients with diabetes mellitus type 2. However, it also causes a substantial rise in low density lipoprotein cholesterol levels and many physicians are therefore hesitant to endorse it. In view of the popular uptake of the keto diet even among subjects not in need of weight loss, there is some preoccupation with the potential long-term consequences of a wide embrace of this diet by large segments of the population. On the contrary, numerous lines of evidence show that plant-based diets are associated with reduction in oncological and cardiovascular diseases and a prolonged life span. The debate reproduced in this article took place during a continuous medical education program between two cardiologists with largely differing views on the matter of effectiveness, sustainability, and safety of the ketogenic diet compared to alternative options.

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Effect of a high-fat Mediterranean diet on bodyweight and waist circumference: a prespecified secondary outcomes analysis of the PREDIMED randomised controlled trial
Estruch, R., Martínez-González, M. A., Corella, D., Salas-Salvadó, J., Fitó, M., Chiva-Blanch, G., Fiol, M., Gómez-Gracia, E., Arós, F., Lapetra, J., et al. (2019) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(19)30074-9 · Cited by 147
Retracted
Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel
Ference, B. A., Ginsberg, H. N., Graham, I., Ray, K. K., Packard, C. J., Bruckert, E., Hegele, R. A., Krauss, R. M., Raal, F. J., Schunkert, H., et al. (2017) · European Heart Journal · doi:10.1093/eurheartj/ehx144 · Cited by 3,962
Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts
Estruch, R., Ros, E., Salas-Salvadó, J., Covas, M.-I., Corella, D., Arós, F., Gómez-Gracia, E., Ruiz-Gutiérrez, V., Fiol, M., Lapetra, J., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1800389 · Cited by 3,616
Bariatric Surgery versus Intensive Medical Therapy for Diabetes — 5-Year Outcomes
Schauer, P. R., Bhatt, D. L., Kirwan, J. P., Wolski, K., Aminian, A., Brethauer, S. A., Navaneethan, S. D., Singh, R. P., Pothier, C. E., Nissen, S. E., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1600869 · Cited by 2,934
Mediterranean Diet, Traditional Risk Factors, and the Rate of Cardiovascular Complications After Myocardial Infarction: Final Report of the Lyon Diet Heart Study
de Lorgeril, M., Salen, P., Martin, J.-L., Monjaud, I., Delaye, J., & Mamelle, N. (1999) · Circulation · doi:10.1161/01.cir.99.6.779 · Cited by 2,910
Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease
de Lorgeril, M., Renaud, S., Salen, P., Monjaud, I., Mamelle, N., Martin, J. L., Guidollet, J., Touboul, P., & Delaye, J. (1994) · The Lancet · doi:10.1016/s0140-6736(94)92580-1 · Cited by 2,122
THE DIET AND 15-YEAR DEATH RATE IN THE SEVEN COUNTRIES STUDY
KEYS, A., MIENOTTI, A., KARVONEN, M. J., ARAVANIS, C., BLACKBURN, H., BUZINA, R., DJORDJEVIC, B. S., DONTAS, A. S., FIDANZA, F., KEYS, M. H., et al. (1986) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114480 · Cited by 1,790
Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease
Siri-Tarino, P. W., Sun, Q., Hu, F. B., & Krauss, R. M. (2010) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.27725 · Cited by 1,253
A 14-Item Mediterranean Diet Assessment Tool and Obesity Indexes among High-Risk Subjects: The PREDIMED Trial
Martínez-González, M. A., García-Arellano, A., Toledo, E., Salas-Salvadó, J., Buil-Cosiales, P., Corella, D., Covas, M. I., Schröder, H., Arós, F., Gómez-Gracia, E., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0043134 · Cited by 1,150
Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study
Dehghan, M., Mente, A., Zhang, X., Swaminathan, S., Li, W., Mohan, V., Iqbal, R., Kumar, R., Wentzel-Viljoen, E., Rosengren, A., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)32252-3 · Cited by 1,101
Effects of Low-Carbohydrate vs Low-Fat Diets on Weight Loss and Cardiovascular Risk Factors: A Meta-analysis of Randomized Controlled Trials
Nordmann, A. J., Nordmann, A., Briel, M., Keller, U., Yancy, W. S., Brehm, B. J., & Bucher, H. C. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.3.285 · Cited by 973
Twenty Year Trends and Sex Differences in Young Adults Hospitalized With Acute Myocardial Infarction
Arora, S., Stouffer, G. A., Kucharska‐Newton, A., Qamar, A., Vaduganathan, M., Pandey, A., Porterfield, D. S., Blankstein, R., Rosamond, W. D., Bhatt, D. L., et al. (2019) · Circulation · doi:10.1161/circulationaha.118.037137 · Cited by 795
Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials
Bueno, N. B., de Melo, I. S. V., de Oliveira, S. L., & da Rocha Ataide, T. (2013) · British Journal of Nutrition · doi:10.1017/s0007114513000548 · Cited by 778
Association of animal and plant protein intake with all-cause and cause-specific mortality.
Song, M., Fung, T. T., Hu, F. B., Willett, W. C., Longo, V. D., Chan, A. T., & Giovannucci, E. L. (2016) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2016.4182 · Cited by 735
Fruit, vegetable, and legume intake, and cardiovascular disease and deaths in 18 countries (PURE): a prospective cohort study
Miller, V., Mente, A., Dehghan, M., Rangarajan, S., Zhang, X., Swaminathan, S., Dagenais, G. R., Gupta, R., Mohan, V., Lear, S. A., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)32253-5 · Cited by 684
Trans Fatty Acids and Coronary Heart Disease
Ascherio, A., Katan, M. B., Zock, P. L., Stampfer, M. J., & Willett, W. C. (1999) · New England Journal of Medicine · doi:10.1056/nejm199906243402511 · Cited by 569
Effects of Saturated Fat, Polyunsaturated Fat, Monounsaturated Fat, and Carbohydrate on Glucose-Insulin Homeostasis: A Systematic Review and Meta-analysis of Randomised Controlled Feeding Trials
Imamura, F., Micha, R., Wu, J. H. Y., Otto, M. C. D. O., Otite, F. O., Abioye, A. I., & Mozaffarian, D. (2016) · PLoS Medicine · doi:10.1371/journal.pmed.1002087 · Cited by 499
Availability, affordability, and consumption of fruits and vegetables in 18 countries across income levels: findings from the Prospective Urban Rural Epidemiology (PURE) study
Miller, V., Yusuf, S., Chow, C. K., Dehghan, M., Corsi, D. J., Lock, K., Popkin, B. M., Rangarajan, S., Khatib, R., Lear, S. A., et al. (2016) · The Lancet Global Health · doi:10.1016/s2214-109x(16)30186-3 · Cited by 455
Effect of a lifestyle intervention program with energy-restricted Mediterranean diet and exercise on weight loss and cardiovascular risk factors: one-year results of the predimed-plus trial
Salas-Salvadó, J., Díaz-López, A., Ruiz-Canela, M., Basora, J., Fitó, M., Corella, D., Serra-Majem, L., Wärnberg, J., Romaguera, D., Estruch, R., et al. (2019) · Diabetes Care · doi:10.2337/dc18-0836 · Cited by 445
Effects of low-carbohydrate diets v. low-fat diets on body weight and cardiovascular risk factors: a meta-analysis of randomised controlled trials
Mansoor, N., Vinknes, K. J., Veierød, M. B., & Retterstøl, K. (2016) · British Journal of Nutrition · doi:10.1017/s0007114515004699 · Cited by 439
Association of dairy intake with cardiovascular disease and mortality in 21 countries from five continents (PURE): a prospective cohort study
Dehghan, M., Mente, A., Rangarajan, S., Sheridan, P., Mohan, V., Iqbal, R., Gupta, R., Lear, S. A., Wentzel‐Viljoen, E., Avezum, Á., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(18)31812-9 · Cited by 438
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Hallberg, S. J., McKenzie, A. L., Williams, P. T., Bhanpuri, N. H., Peters, A. L., Campbell, W. W., Hazbun, T. L., Volk, B. M., McCarter, J. P., Phinney, S. D., et al. (2018) · Diabetes Therapy · doi:10.1007/s13300-018-0373-9 · Cited by 406
Clinical implications of discordance between low-density lipoprotein cholesterol and particle number
Otvos, J. D., Mora, S., SHALAUROVA, I. Y., Greenland, P., Mackey, R. H., & Goff, D. C. (2011) · Journal of clinical lipidology · doi:10.1016/j.jacl.2011.02.001 · Cited by 385
LDL particle subclasses, LDL particle size, and carotid atherosclerosis in the Multi-Ethnic Study of Atherosclerosis (MESA)
Mora, S., Szklo, M., Otvos, J. D., Greenland, P., Psaty, B. M., Goff, D. C., O’Leary, D. H., Saad, M. F., Tsai, M. Y., & Sharrett, A. R. (2007) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2006.05.007 · Cited by 380
Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73)
Ramsden, C. E., Zamora, D., Majchrzak‐Hong, S. F., Faurot, K. R., Broste, S. K., Frantz, R. P., Davis, J. M., Ringel, A., Suchindran, C., & Hibbeln, J. R. (2016) · BMJ · doi:10.1136/bmj.i1246 · Cited by 373
Hyperinsulinemia Predicts Coronary Heart Disease Risk in Healthy Middle-aged Men
Pyörälä, M., Miettinen, H., Laakso, M., & Pyörälà, K. (1998) · Circulation · doi:10.1161/01.cir.98.5.398 · Cited by 346
Energy expenditure and body composition changes after an isocaloric ketogenic diet in overweight and obese men
Hall, K. D., Chen, K. Y., Guo, J., Lam, Y. Y., Leibel, R. L., Mayer, L. E., Reitman, M. L., Rosenbaum, M., Smith, S. R., Walsh, B. T., et al. (2016) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.133561 · Cited by 330
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Separate effects of reduced carbohydrate intake and weight loss on atherogenic dyslipidemia
Krauss, R. M., Blanche, P. J., Rawlings, R. S., Fernstrom, H. S., & Williams, P. T. (2006) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/83.5.1025 · Cited by 321
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Teo, K., Lear, S., Islam, S., Mony, P., Dehghan, M., Li, W., Rosengren, A., Lopez-Jaramillo, P., Diaz, R., Oliveira, G., et al. (2013) · JAMA · doi:10.1001/jama.2013.3519 · Cited by 305
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Kwiterovich, P. O. (2003) · JAMA · doi:10.1001/jama.290.7.912 · Cited by 289
Association of dietary nutrients with blood lipids and blood pressure in 18 countries: a cross-sectional analysis from the PURE study
Mente, A., Dehghan, M., Rangarajan, S., McQueen, M., Dagenais, G., Wielgosz, A., Lear, S., Li, W., Chen, H., Yi, S., et al. (2017) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(17)30283-8 · Cited by 268
The Metabolic Syndrome, LDL Particle Size, and Atherosclerosis
Hulthe, J., Bokemark, L., Wikstrand, J., & Fagerberg, B. (2000) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.20.9.2140 · Cited by 249
Selective Insulin Resistance and the Development of Cardiovascular Diseases in Diabetes: The 2015 Edwin Bierman Award Lecture
King, G. L., Park, K., & Li, Q. (2016) · Diabetes · doi:10.2337/db16-0152 · Cited by 232
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Keys, A. B. (1957) · JAMA · doi:10.1001/jama.1957.62980170024007e · Cited by 228
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Tahara, N., Kai, H., Yamagishi, S., Mizoguchi, M., Nakaura, H., Ishibashi, M., Kaida, H., Baba, K., Hayabuchi, N., & Imaizumi, T. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.11.046 · Cited by 224
Dietary Intervention for Overweight and Obese Adults: Comparison of Low-Carbohydrate and Low-Fat Diets. A Meta-Analysis
Sackner-Bernstein, J., Kanter, D., & Kaul, S. (2015) · PLOS ONE · doi:10.1371/journal.pone.0139817 · Cited by 220
Differential Role of Adipose Tissues in Obesity and Related Metabolic and Vascular Complications
Gómez‐Hernández, A., Beneit, N., Díaz-Castroverde, S., & Escribano, Ó. (2016) · International Journal of Endocrinology · doi:10.1155/2016/1216783 · Cited by 211
Dietary carbohydrate restriction improves metabolic syndrome independent of weight loss
Hyde, P. N., Sapper, T. N., Crabtree, C. D., LaFountain, R. A., Bowling, M. L., Buga, A., Fell, B., McSwiney, F. T., Dickerson, R. M., Miller, V. J., et al. (2019) · JCI Insight · doi:10.1172/jci.insight.128308 · Cited by 210
Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality in a Japanese Cohort
Budhathoki, S., Sawada, N., Iwasaki, M., Yamaji, T., Goto, A., Kotemori, A., Ishihara, J., Takachi, R., Charvat, H., Mizoue, T., et al. (2019) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2019.2806 · Cited by 203
Cardiovascular disease risk factor responses to a type 2 diabetes care model including nutritional ketosis induced by sustained carbohydrate restriction at 1 year: an open label, non-randomized, controlled study
Bhanpuri, N. H., Hallberg, S. J., Williams, P. T., McKenzie, A. L., Ballard, K. D., Campbell, W. W., McCarter, J. P., Phinney, S. D., & Volek, J. S. (2018) · Cardiovascular Diabetology · doi:10.1186/s12933-018-0698-8 · Cited by 190
Diet, lifestyle, and the etiology of coronary artery disease: the Cornell China Study
Campbell, T. C., Parpia, B., & Chen, J. (1998) · The American Journal of Cardiology · doi:10.1016/s0002-9149(98)00718-8 · Cited by 178
Evidence from randomised controlled trials did not support the introduction of dietary fat guidelines in 1977 and 1983: a systematic review and meta-analysis
Harcombe, Z., Baker, J. S., Cooper, S. M., Davies, B., Sculthorpe, N. F., DiNicolantonio, J. J., & Grace, F. (2015) · Open Heart · doi:10.1136/openhrt-2014-000196 · Cited by 165
Systematic review: association of low-density lipoprotein subfractions with cardiovascular outcomes.
Ip, S., Lichtenstein, A. H., Chung, M., Lau, J., & Balk, E. M. (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-150-7-200904070-00007 · Cited by 163
Association of apolipoprotein B and nuclear magnetic resonance spectroscopy-derived LDL particle number with outcomes in 25 clinical studies: assessment by the AACC Lipoprotein and Vascular Diseases Division Working Group on Best Practices
Cole, T. G., Contois, J. H., Csako, G., McConnell, J. P., Remaley, A. T., Devaraj, S., Hoefner, D. M., Mallory, T., Sethi, A. A., & Warnick, G. R. (2013) · Clinical Chemistry · doi:10.1373/clinchem.2012.196733 · Cited by 122
Letter on Corpulence, Addressed to the Public
Banting, W. (1993) · Obesity Research · doi:10.1002/j.1550-8528.1993.tb00605.x · Cited by 120
Association between red meat consumption and metabolic syndrome in a Mediterranean population at high cardiovascular risk: Cross-sectional and 1-year follow-up assessment
Babió, N., Sorlí, M., Bulló, M., Basora, J., Ibarrola-Jurado, N., Fernandez-Ballart, J. D., Martínez‐González, M. Á., Serra‐Majem, L., González-Pérez, R., & Salas‐Salvadó, J. (2010) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2010.06.011 · Cited by 114
Effect of low carbohydrate high fat diet on LDL cholesterol and gene expression in normal-weight, young adults: A randomized controlled study
Retterstøl, K., Svendsen, M., Narverud, I., & Holven, K. B. (2018) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2018.10.013 · Cited by 104
Associations between very low concentrations of low density lipoprotein cholesterol, high sensitivity C-reactive protein, and health outcomes in the Reasons for Geographical and Racial Differences in Stroke (REGARDS) study
Penson, P. E., Long, D. L., Howard, G., Toth, P. P., Muntner, P., Howard, V. J., Safford, M. M., Jones, S. R., Martin, S. S., Mazidi, M., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy533 · Cited by 89
Statistical review of US macronutrient consumption data, 1965–2011: Americans have been following dietary guidelines, coincident with the rise in obesity
Cohen, E., Cragg, M. I., deFonseka, J., Hite, A. H., Rosenberg, M., & Zhou, B. (2015) · Nutrition · doi:10.1016/j.nut.2015.02.007 · Cited by 86
Fat, Sugar, Whole Grains and Heart Disease: 50 Years of Confusion
Temple, N. J. (2018) · Nutrients · doi:10.3390/nu10010039 · Cited by 85
Cardiovascular risk in patients achieving low-density lipoprotein cholesterol and particle targets
Toth, P. P., Grabner, M., Punekar, R. S., Quimbo, R. A., Cziraky, M. J., & Jacobson, T. A. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.05.914 · Cited by 62
Comparative prognostic utility of conventional and novel lipid parameters for cardiovascular disease risk prediction: Do novel lipid parameters offer an advantage?
Manickam, P., Rathod, A. D., Panaich, S., Hari, P., Veeranna, V., Badheka, A., Jacob, S., & Afonso, L. (2010) · Journal of clinical lipidology · doi:10.1016/j.jacl.2010.12.001 · Cited by 31
The Seven Countries Study
Pett, K. D., Willett, W. C., Vartiainen, E. A., & Katz, D. L. (2017) · European Heart Journal · doi:10.1093/eurheartj/ehx603 · Cited by 26
Coronary Heart Disease Deaths And Decreased Smoking Prevalence in Massachusetts, 1993–2003
Kabir, Z., Connolly, G. N., Clancy, L., Koh, H. K., & Capewell, S. (2008) · American Journal of Public Health · doi:10.2105/ajph.2007.129924 · Cited by 19
Association of low-density lipoprotein pattern with mortality after myocardial infarction: Insights from the TRIUMPH study
Pokharel, Y., Tang, Y., Bhardwaj, B., Patel, K., Qintar, M., O’Keefe, J. H., Kulkarni, K. R., Jones, P. H., Martin, S. S., Virani, S. S., et al. (2017) · Journal of clinical lipidology · doi:10.1016/j.jacl.2017.09.002 · Cited by 18
Association between fasting insulin and high-sensitivity C reactive protein in Korean adults
Yang, J. S., Gerber, J. N., & You, H. J. (2017) · BMJ Open Sport & Exercise Medicine · doi:10.1136/bmjsem-2017-000236 · Cited by 11
Oxidized LDL as A Biomarker in Metabolic Syndrome
Ali, W., Kushwaha, U., Wamique, M., Vishwakarma, P., Tasleem, M., Khan, M., & Kumar, A. (2017) · Journal of Diabetes & Metabolism · doi:10.4172/2155-6156.1000764 · Cited by 4
Abstract P3054: A Cultural Dance Program Proves Efficacious for Hypertension Control: A Randomized Controlled Trial
Kaholokula, J. K., Mabellos, T., Choi, S. Y., Seto, T. B., Wills, T. A., de Silva, M., Dillard, A. Y., Gonsalves, J., Seabury, A. A., Vegas, J. K., et al. (2019) · Hypertension · doi:10.1161/hyp.74.suppl_1.p3054 · Cited by 1

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Authors: O'Neill, B., & Raggi, P.
Affiliations: University of Alberta (CA)
Corresponding author: Raggi, Paolo
ORCID: Raggi, Paolo
Venue: Atherosclerosis
Publisher: Elsevier BV
Published: 2020-01
Volume: 292
Pages: 119-126
ISSN: 0021-9150 (ISSN-L)
DOI: 10.1016/j.atherosclerosis.2019.11.021
OpenAlex: W2990060012
Cited by: 219
References: 59
Citations by year: 2026: 17 · 2025: 37 · 2024: 45 · 2023: 45 · 2022: 31 · 2021: 29 · 2020: 15
FWCI: 2.21
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Atherosclerosis (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Physiology (medical) › Diet and metabolism studies
Health Sciences › Medicine › Physiology (medical) › Dietary Effects on Health
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Keywords: ketogenic diet, weight loss, cardiovascular risk, LDL cholesterol, type 2 diabetes, glycemic control, saturated fat, plant-based diet, diet sustainability, diet safety
MeSH terms: Diet, Reducing, Humans, Diet, Ketogenic

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The ketogenic diet: Pros and cons

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