A longitudinal study of speech production in primary progressive aphasia and behavioral variant frontotemporal dementia
Open accessAbstract
We examined longitudinal change in language expression during a semi-structured speech sample in 48 patients with primary progressive aphasia (PPA) or behavioral variant frontotemporal dementia (bvFTD) and related this to longitudinal neuroimaging of cortical thickness available in 25 of these patients. All patient groups declined significantly on measures of both speech fluency and grammar, although patients with nonfluent/agrammatic PPA (naPPA) declined to a greater extent than patients with the semantic variant, the logopenic variant, and bvFTD. These patient groups also declined on several neuropsychological measures, but there was no correlation between decline in speech expression and decline in neuropsychological performance. Longitudinal decline in grammaticality, assessed by the number of well-formed sentences produced, was associated with longitudinal progression of gray matter atrophy in left frontal operculum/insula and bilateral temporal cortex.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Semi-structured speech samples captured decline of fluency and grammaticality (2 years), associated with frontotemporal atrophy (N = 14).
“Promising digital tools may increase the sensitivity of cognitive assessment, such as semi-structured speech samples that captured decline of fluency and grammaticality (2 years), associated with frontotemporal atrophy (N = 14) (Ash et al., 2019).”
From The pursuit for markers of disease progression in behavioral variant frontotemporal dementia: a scoping review to optimize outcome measures for clinical trials (2024) · cites this paper as Ash et al., 2019
In behavioural variant frontotemporal dementia, ASLA captures prosodic and linguistic alterations as well as their worsening in the course of disease.
“In behavioural variant frontotemporal dementia, they capture prosodic 24 and linguistic 72 alterations as well as their worsening in the course of dis ease. 57”
From Speech and language markers of neurodegeneration: a call for global equity (2023) · cites this paper as [57]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia
Rascovsky, K., Hodges, J. R., Knopman, D., Mendez, M. F., Kramer, J. H., Neuhaus, J., van Swieten, J. C., Seelaar, H., Dopper, E. G. P., Onyike, C. U., et al. (2011) · Brain · doi:10.1093/brain/awr179 · Cited by 5,221 · see citing works
Self-citationClassification of primary progressive aphasia and its variants
Gorno-Tempini, M. L., Hillis, A. E., Weintraub, S., Kertesz, A., Mendez, M., Cappa, S. F., Ogar, J. M., Rohrer, J. D., Black, S., Boeve, B. F., et al. (2011) · Neurology · doi:10.1212/wnl.0b013e31821103e6 · Cited by 5,141 · see citing works
Self-citationForman, S. D., Cohen, J. D., Fitzgerald, M., Eddy, W. F., Mintun, M. A., & Noll, D. C. (1995) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910330508 · Cited by 3,202 · see citing works
Weıntraub, S. (1990) · Archives of Neurology · doi:10.1001/archneur.1990.00530120075013 · Cited by 3,012 · see citing works
Appelhof, B., Bakker, C., den IJssel, J. C. L. V. D., Zwijsen, S. A., Smalbrugge, M., Verhey, F. R. J., de Vugt, M. E., Zuidema, S. U., & Koopmans, R. T. C. M. (2017) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000477087 · Cited by 2,773 · see citing works
Qualitative Assessment of Verbal Fluency Performance in Frontotemporal Dementia
van den Berg, E., Jiskoot, L. C., Grosveld, M. J. H., Swieten, J. C. V., & Papma, J. M. (2017) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000477538 · Cited by 2,061 · see citing works
Hécaen, H. (1983) · Neuropsychologia · doi:10.1016/0028-3932(83)90089-1 · Cited by 1,700 · see citing works
Cognition and anatomy in three variants of primary progressive aphasia
Gorno‐Tempini, M. L., Dronkers, N. F., Rankin, K. P., Ogar, J. M., Phengrasamy, L., Rosen, H. J., Johnson, J. K., Weiner, M. W., & Miller, B. L. (2004) · Annals of Neurology · doi:10.1002/ana.10825 · Cited by 1,608 · see citing works
Grammatical structures written at three grade levels
Hunt, K. W. (1965) · Cited by 996 · see citing works
FMRI Clustering in AFNI: False-Positive Rates Redux
Cox, R., Chen, G., Glen, D., Reynolds, R., & Taylor, P. (2017) · Brain Connectivity · doi:10.1089/brain.2016.0475 · Cited by 792 · see citing works
Semantic dementia: a unique clinicopathological syndrome
Hodges, J. R., & Patterson, K. (2007) · The Lancet Neurology · doi:10.1016/s1474-4422(07)70266-1 · Cited by 772 · see citing works
Boston diagnostic aphasia examination
Goodglass, H. (2013) · SpringerReference · doi:10.1007/springerreference_183639 · Cited by 696 · see citing works
Large-scale evaluation of ANTs and FreeSurfer cortical thickness measurements
Tustison, N. J., Cook, P. A., Klein, A., Song, G., Das, S. R., Duda, J. T., Kandel, B. M., van Strien, N., Stone, J. R., Gee, J. C., et al. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2014.05.044 · Cited by 670 · see citing works
An Open Source Multivariate Framework for n-Tissue Segmentation with Evaluation on Public Data
Avants, B., Tustison, N. J., Wu, J., Cook, P. A., & Gee, J. C. (2011) · Neuroinformatics · doi:10.1007/s12021-011-9109-y · Cited by 559 · see citing works
Connected speech production in three variants of primary progressive aphasia
Wilson, S. M., Henry, M. L., Besbris, M., Ogar, J. M., Dronkers, N. F., Jarrold, W., Miller, B. L., & Gorno-Tempini, M. L. (2010) · Brain · doi:10.1093/brain/awq129 · Cited by 546 · see citing works
Linear mixed-effects modeling approach to FMRI group analysis
Chen, G., Saad, Z. S., Britton, J. C., Pine, D. S., & Cox, R. W. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.01.047 · Cited by 440 · see citing works
Primary progressive aphasia: clinicopathological correlations
Grossman, M. (2010) · Nature Reviews Neurology · doi:10.1038/nrneurol.2009.216 · Cited by 414 · see citing works
Self-citationPrimary progressive aphasia and the evolving neurology of the language network
Mesulam, M. M., Rogalski, E. J., Wieneke, C., Hurley, R. S. E., Geula, C., Bigio, E. H., Thompson, C. K., & Weıntraub, S. (2014) · Nature Reviews Neurology · doi:10.1038/nrneurol.2014.159 · Cited by 386 · see citing works
Quantitative classification of primary progressive aphasia at early and mild impairment stages
Mesulam, M. M., Wieneke, C., Thompson, C. K., Rogalski, E., & Weıntraub, S. (2012) · Brain · doi:10.1093/brain/aws080 · Cited by 342 · see citing works
Progressive non-fluent aphasia is associated with hypometabolism centred on the left anterior insula
Nestor, P. J. (2003) · Brain · doi:10.1093/brain/awg240 · Cited by 322 · see citing works
Nonfluent progressive aphasia and semantic dementia: A comparative neuropsychological study
Hodges, J. R., & Patterson, K. E. (1996) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617700001685 · Cited by 301 · see citing works
Progressive logopenic/phonological aphasia: Erosion of the language network
Rohrer, J. D., Ridgway, G. R., Crutch, S. J., Hailstone, J. C., Goll, J. C., Clarkson, M. J., Mead, S., Beck, J. A., Mummery, C. J., Sebastien Ourselin, A., et al. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.08.002 · Cited by 294 · see citing works
Quantitative Template for Subtyping Primary Progressive Aphasia
Mesulam, M. M., Wieneke, C. A., Rogalski, E. J., Cobia, D. J., Thompson, C. K., & Weıntraub, S. (2009) · Archives of Neurology · doi:10.1001/archneurol.2009.288 · Cited by 257 · see citing works
Progression of language decline and cortical atrophy in subtypes of primary progressive aphasia
Rogalski, E., Cobia, D., Harrison, T. M., Wieneke, C., Weintraub, S., & Mesulam, M.-M. (2011) · Neurology · doi:10.1212/wnl.0b013e31821ccd3c · Cited by 252 · see citing works
The non-fluent/agrammatic variant of primary progressive aphasia
Grossman, M. (2012) · The Lancet Neurology · doi:10.1016/s1474-4422(12)70099-6 · Cited by 231 · see citing works
Self-citationGrossman, M., Mickanin, J., Onishi, K., Hughes, E., D’Esposito, M., Xin-sheng, D., Alavi, A. A., & Reivich, M. (1996) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.1996.8.2.135 · Cited by 216 · see citing works
Self-citationAnatomy of Language Impairments in Primary Progressive Aphasia
Rogalski, E. J., Cobia, D. J., Harrison, T. M., Wieneke, C. A., Thompson, C. K., Weıntraub, S., & Mesulam, M. M. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.5544-10.2011 · Cited by 209 · see citing works
Ash, S., Moore, P., Antani, S., McCawley, G., Work, M., & Grossman, M. (2006) · Neurology · doi:10.1212/01.wnl.0000210435.72614.38 · Cited by 204 · see citing works
Self-citationPrevalence of amyloid‐β pathology in distinct variants of primary progressive aphasia
Bergeron, D., Gorno‐Tempini, M. L., Rabinovici, G. D., Santos‐Santos, M. A., Seeley, W., Miller, B. L., Pijnenburg, Y., Keulen, M. A., Groot, C., van Berckel, B. N. M., et al. (2018) · Annals of Neurology · doi:10.1002/ana.25333 · Cited by 203 · see citing works
Self-citationFrom the left to the right: How the brain compensates progressive loss of language function
Thiel, A., Habedank, B., Herholz, K., Kessler, J., Winhuisen, L., Haupt, W. F., & Heiss, W. (2006) · Brain and Language · doi:10.1016/j.bandl.2006.01.007 · Cited by 183 · see citing works
Differentiating primary progressive aphasias in a brief sample of connected speech
Ash, S., Evans, E., O'Shea, J., Powers, J., Boller, A., Weinberg, D., Haley, J., McMillan, C., Irwin, D. J., Rascovsky, K., et al. (2013) · Neurology · doi:10.1212/wnl.0b013e31829c5d0e · Cited by 171 · see citing works
Self-citationCroot, K., Ballard, K. J., Leyton, C. E., & Hodges, J. R. (2012) · Journal of Speech Language and Hearing Research · doi:10.1044/1092-4388(2012/11-0323 · Cited by 156 · see citing works
Patterns of language decline in non-fluent primary progressive aphasia
Thompson, C. K., Ballard, K. J., Tait, M. E., Weıntraub, S., & Mesulam, M. M. (1997) · Aphasiology · doi:10.1080/02687039708248473 · Cited by 149 · see citing works
Clinical marker for Alzheimer disease pathology in logopenic primary progressive aphasia
Giannini, L. A. A., Irwin, D. J., McMillan, C. T., Ash, S., Rascovsky, K., Wolk, D. A., Van Deerlin, V. M., Lee, E. B., Trojanowski, J. Q., & Grossman, M. (2017) · Neurology · doi:10.1212/wnl.0000000000004034 · Cited by 144 · see citing works
Self-citationNon-fluent speech in frontotemporal lobar degeneration
Ash, S., Moore, P., Vesely, L., Gunawardena, D., McMillan, C. T., Anderson, C., Avants, B., & Grossman, M. (2009) · Journal of Neurolinguistics · doi:10.1016/j.jneuroling.2008.12.001 · Cited by 140 · see citing works
Self-citationTurkstra, L. S. (2018) · Springer eBooks · doi:10.1007/978-3-319-56782-2_937-3 · Cited by 134 · see citing works
Patterns of longitudinal brain atrophy in the logopenic variant of primary progressive aphasia
Rohrer, J. D., Caso, F., Mahoney, C., Henry, M. L., Rosen, H. J., Rabinovici, G. D., Rossor, M. N., Miller, B. L., Warren, J. D., Fox, N. C., et al. (2013) · Brain and Language · doi:10.1016/j.bandl.2012.12.008 · Cited by 130 · see citing works
Making sense of progressive non-fluent aphasia: an analysis of conversational speech
Knibb, J. A., Woollams, A. M., Hodges, J. R., & Patterson, K. E. (2009) · Brain · doi:10.1093/brain/awp207 · Cited by 125 · see citing works
Right hemisphere grey matter structure and language outcomes in chronic left hemisphere stroke.
Xing, S.-H., Lacey, E., Skipper-Kallal, L. M., Jiang, X., Harris-Love, M., Zeng, J.-S., & Turkeltaub, P. (2016) · Brain : a journal of neurology · doi:10.1093/brain/awv323 · Cited by 124 · see citing works
Bonner, M., Ash, S., & Grossman, M. (2010) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-010-0140-4 · Cited by 119 · see citing works
Self-citationHope, T. M. H., Leff, A. P., Prejawa, S., Bruce, R. M., Haigh, Z., Lim, L., Ramsden, S., Oberhuber, M., Ludersdorfer, P., Crinion, J., et al. (2017) · Brain · doi:10.1093/brain/awx086 · Cited by 106 · see citing works
Ballard, K. J., Savage, S., Leyton, C. E., Vogel, A. P., Hornberger, M., & Hodges, J. R. (2014) · PLoS ONE · doi:10.1371/journal.pone.0089864 · Cited by 105 · see citing works
Asymmetry of cortical decline in subtypes of primary progressive aphasia
Rogalski, E. J., Cobia, D. J., Martersteck, A., RADEMAKER, A. W., Wieneke, C. A., Weıntraub, S., & Mesulam, M. M. (2014) · Neurology · doi:10.1212/wnl.0000000000000824 · Cited by 100 · see citing works
Brambati, S. M., Amici, S., Racine, C. A., Neuhaus, J. M., Miller, Z., Ogar, J., Dronkers, N., Miller, B. L., Rosen, H., & Gorno‐Tempini, M. L. (2015) · NeuroImage Clinical · doi:10.1016/j.nicl.2015.01.011 · Cited by 96 · see citing works
Why are patients with progressive nonfluent aphasia nonfluent?
Gunawardena, D., Ash, S., McMillan, C. T., Avants, B., Gee, J. C., & Grossman, M. (2010) · Neurology · doi:10.1212/wnl.0b013e3181ed9c7d · Cited by 95 · see citing works
Self-citationGrossman, M., Powers, J., Ash, S., McMillan, C. T., Burkholder, L., Irwin, D. J., & Trojanowski, J. Q. (2012) · Brain and Language · doi:10.1016/j.bandl.2012.10.005 · Cited by 91 · see citing works
Self-citationBrain and ventricular volumetric changes in frontotemporal lobar degeneration over 1 year
Knopman, D. S., Jack, C. R., Kramer, J. H., Boeve, B. F., Caselli, R. J., Graff-Radford, N. R., Mendez, M. F., Miller, B. L., & Mercaldo, N. D. (2009) · Neurology · doi:10.1212/wnl.0b013e3181a71236 · Cited by 85 · see citing works
Bright, P., Moss, H. E., Stamatakis, E. A., & TYLER, L. K. (2008) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2008.02.019 · Cited by 81 · see citing works
Sentence Processing in Frontotemporal Dementia
Grossman, M., Rhee, J., & Moore, P. (2005) · Cortex · doi:10.1016/s0010-9452(08)70295-8 · Cited by 72 · see citing works
Self-citationLongitudinal structural and molecular neuroimaging in agrammatic primary progressive aphasia
Tetzloff, K. A., Duffy, J. R., Clark, H. M., Strand, E. A., Machulda, M. M., Schwarz, C. G., Senjem, M. L., Reid, R. I., Spychalla, A. J., Tosakulwong, N., et al. (2017) · Brain · doi:10.1093/brain/awx293 · Cited by 62 · see citing works
Automatic measurement of prosody in behavioral variant FTD
Nevler, N., Ash, S., Jester, C., Irwin, D. J., Liberman, M., & Grossman, M. (2017) · Neurology · doi:10.1212/wnl.0000000000004236 · Cited by 61 · see citing works
Self-citationVisuospatial Functioning in the Primary Progressive Aphasias
Watson, C., Possin, K., Allen, I., Hubbard, H., Meyer, M., Welch, A. E., Rabinovici, G., Rosen, H., Rankin, K. P., Miller, Z., et al. (2017) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617717000984 · Cited by 59 · see citing works
Peelle, J. E., Cooke, A., Moore, P., Vesely, L., & Grossman, M. (2007) · Journal of Neurolinguistics · doi:10.1016/j.jneuroling.2007.04.002 · Cited by 59 · see citing works
Self-citationA longitudinal study of sentence comprehension difficulty in primary progressive aphasia
Grossman, M. (2005) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2004.039966 · Cited by 58 · see citing works
Self-citationGrammatical comprehension deficits in non-fluent/agrammatic primary progressive aphasia
Charles, D., Olm, C. A., Powers, J., Ash, S., Irwin, D. J., McMillan, C. T., Rascovsky, K., & Grossman, M. (2013) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2013-305749 · Cited by 58 · see citing works
Self-citationCousins, K. A. Q., York, C., Bauer, L., & Grossman, M. (2016) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2016.02.025 · Cited by 57 · see citing works
Self-citationVariable disruption of a syntactic processing network in primary progressive aphasia
Wilson, S. M., DeMarco, A. T., Henry, M. L., Gesierich, B. G., Babiak, M. C., Miller, B. L., & Gorno‐Tempini, M. L. (2016) · Brain · doi:10.1093/brain/aww218 · Cited by 57 · see citing works
Tu, S., Leyton, C. E., Hodges, J. R., Piguet, O., & Hornberger, M. (2015) · Journal of Alzheimer s Disease · doi:10.3233/jad-150626 · Cited by 56 · see citing works
Anterior temporal laterality in primary progressive aphasia shifts to the right
Vandenbulcke, M., Peeters, R. R., Hecke, P. V., & Vandenberghe, R. R. (2005) · Annals of Neurology · doi:10.1002/ana.20588 · Cited by 56 · see citing works
Linguistic Aspects of Primary Progressive Aphasia
Grossman, M. (2017) · Annual Review of Linguistics · doi:10.1146/annurev-linguistics-011516-034253 · Cited by 44 · see citing works
Self-citationDissociable substrates underlie the production of abstract and concrete nouns
Cousins, K. A. Q., Ash, S., Irwin, D. J., & Grossman, M. (2016) · Brain and Language · doi:10.1016/j.bandl.2016.11.003 · Cited by 37 · see citing works
Self-citationEtcheverry, L., Seidel, B., Grande, M., Schulte, S., Pieperhoff, P., Südmeyer, M., Minnerop, M., Binkofski, F., Huber, W., Grodzinsky, Y., et al. (2012) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2012.03.028 · Cited by 34 · see citing works
Cousins, K. A. Q., Ash, S., Olm, C. A., & Grossman, M. (2018) · eneuro · doi:10.1523/eneuro.0197-18.2018 · Cited by 30 · see citing works
Self-citationNelissen, N., Dupont, P. J., Vandenbulcke, M., Tousseyn, T., Peeters, R. R., & Vandenberghe, R. R. (2011) · Journal of Molecular Neuroscience · doi:10.1007/s12031-011-9603-6 · Cited by 29 · see citing works
Healey, M. L., McMillan, C. T., Golob, S., Spotorno, N., Rascovsky, K., Irwin, D. J., Clark, R., & Grossman, M. (2015) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2015.01.028 · Cited by 28 · see citing works
Self-citationOlm, C. A., Kandel, B. M., Avants, B., Detre, J. A., Gee, J. C., Grossman, M., & McMillan, C. T. (2016) · Journal of Neurology · doi:10.1007/s00415-016-8221-1 · Cited by 27 · see citing works
Self-citationFaria, A. V., Sebastian, R., Newhart, M., Mori, S., & Hillis, A. E. (2014) · Aphasiology · doi:10.1080/02687038.2014.911241 · Cited by 22 · see citing works
Longitudinal changes in brains of patients with fluent primary progressive aphasia
Heim, S., Pieperhoff, P., Grande, M., Kuijsten, W., Wellner, B., Sáez, L. E., Schulte, S., Südmeyer, M., Caspers, S., Minnerop, M., et al. (2013) · Brain and Language · doi:10.1016/j.bandl.2013.05.012 · Cited by 18 · see citing works
Lack of Frank Agrammatism in the Nonfluent Agrammatic Variant of Primary Progressive Aphasia
Graham, N. L., Léonard, C., Tang‐Wai, D. F., Black, S. E., Chow, T. W., Scott, C. J. M., McNeely, A. A., Masellis, M., & Rochon, E. A. (2016) · Dementia and Geriatric Cognitive Disorders Extra · doi:10.1159/000448944 · Cited by 16 · see citing works
Tree, J. J., & Kay, J. (2014) · Journal of Neuropsychology · doi:10.1111/jnp.12045 · Cited by 14 · see citing works
Cousins, K. A. Q., & Grossman, M. (2017) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000498 · Cited by 14 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Frontotemporal lobar degeneration
Grossman, M., Seeley, W. W., Boxer, A. L., Hillis, A. E., Knopman, D. S., Ljubenov, P. A., Miller, B., Piguet, O., Rademakers, R., Whitwell, J. L., et al. (2023) · Nature Reviews Disease Primers · doi:10.1038/s41572-023-00447-0 · Cited by 178 · see citing works
Self-citationSpeech and language markers of neurodegeneration: a call for global equity
García, A. M., de Leon, J., Tee, B. L., Blasi, D. E., & Gorno-Tempini, M. L. (2023) · Brain · doi:10.1093/brain/awad253 · Cited by 102 · see citing works
Speech and language impairments in behavioral variant frontotemporal dementia: A systematic review
Geraudie, A., Battista, P., García, A. M., Allen, I. E., Miller, Z. A., Gorno-Tempini, M. L., & Montembeault, M. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.10.015 · Cited by 80 · see citing works
The natural history of primary progressive aphasia: beyond aphasia
Ulugut, H., Stek, S., Wagemans, L. E. E., Jutten, R. J., Keulen, M. A., Bouwman, F. H., Prins, N. D., Lemstra, A. W., Krudop, W. A., Teunissen, C. E., et al. (2021) · Journal of Neurology · doi:10.1007/s00415-021-10689-1 · Cited by 63 · see citing works
Suárez‐González, A., Cassani, A., Gopalan, R., Stott, J., & Savage, S. (2021) · Alzheimer's & Dementia: Translational Research & Clinical Interventions · doi:10.1002/trc2.12205 · Cited by 46 · see citing works
Modelling the cascade of biomarker changes in GRN-related frontotemporal dementia
Panman, J. L., Venkatraghavan, V., van der Ende, E. L., Steketee, R. M. E., Jiskoot, L. C., Poos, J. M., Dopper, E. G. P., Meeter, L. H. H., Kaat, L. D., Rombouts, S. A. R. B., et al. (2021) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2020-323541 · Cited by 38 · see citing works
Sablonnière, J. D. L., Tastevin, M., Lavoie, M., & Laforce, R. J. (2021) · Brain Sciences · doi:10.3390/brainsci11091209 · Cited by 38 · see citing works
García, A. M., Johann, F., Echegoyen, R. E., Calcaterra, C., Riera, P., Belloli, L. M. L., & Carrillo, F. (2023) · Behavior Research Methods · doi:10.3758/s13428-023-02240-z · Cited by 29 · see citing works
Tastevin, M., Lavoie, M., Sablonnière, J. D. L., Carrier‐Auclair, J., & Laforce, R. J. (2021) · Brain Sciences · doi:10.3390/brainsci11091113 · Cited by 28 · see citing works
Mapping behavioural, cognitive and affective transdiagnostic dimensions in frontotemporal dementia
Ramanan, S., El-Omar, H., Roquet, D., Ahmed, R. M., Hodges, J. R., Piguet, O., Ralph, M. A. L., & Irish, M. (2022) · Brain Communications · doi:10.1093/braincomms/fcac344 · Cited by 26 · see citing works
Digital Speech Analysis in Progressive Supranuclear Palsy and Corticobasal Syndromes
Parjane, N., Cho, S., Ash, S., Cousins, K. A. Q., Shellikeri, S., Liberman, M., Shaw, L. M., Irwin, D. J., Grossman, M., & Nevler, N. (2021) · Journal of Alzheimer's Disease · doi:10.3233/jad-201132 · Cited by 24 · see citing works
Self-citationHaley, K. L., Jacks, A., Jarrett, J., Ray, T., Cunningham, K. T., Gorno‐Tempini, M. L., & Henry, M. L. (2021) · Journal of Speech Language and Hearing Research · doi:10.1044/2020_jslhr-20-00445 · Cited by 24 · see citing works
Volkmer, A., Cross, L., Highton, L., Jackson, C., Smith, C., Brotherhood, E., Harding, E., Mummery, C. J., Rohrer, J. D., Weil, R. S., et al. (2024) · International Journal of Language & Communication Disorders · doi:10.1111/1460-6984.13018 · Cited by 21 · see citing works
Brain changes underlying progression of speech motor programming impairment
Landín-Romero, R., Liang, C. T., Monroe, P., Higashiyama, Y., Leyton, C. E., Hodges, J. R., Piguet, O., & Ballard, K. J. (2021) · Brain Communications · doi:10.1093/braincomms/fcab205 · Cited by 21 · see citing works
Four dimensions of naturalistic language production in aphasia after stroke
Casilio, M., Kasdan, A. V., Bryan, K. M., Shibata, K., Schneck, S. M., Levy, D. F., Entrup, J. L., Onuscheck, C. F., de Riesthal, M. R., & Wilson, S. M. (2024) · Brain · doi:10.1093/brain/awae195 · Cited by 12 · see citing works
Montembeault, M., Miller, Z., Geraudie, A., Pressman, P., Slegers, A., Millanski, C., Licata, A. E., Ratnasiri, B. M., Mandelli, M. L., Henry, M. L., et al. (2023) · Brain Communications · doi:10.1093/braincomms/fcad077 · Cited by 11 · see citing works
Gkintoni, E., & Michou, E. (2024) · Brain Sciences · doi:10.3390/brainsci14121234 · Cited by 11 · see citing works
The neurobiology of sentence production: A narrative review and meta-analysis
Yeaton, J. (2025) · Brain and Language · doi:10.1016/j.bandl.2025.105549 · Cited by 9 · see citing works
Robin, J., Xu, M., Kaufman, L. D., Simpson, W. S., McCaughey, S. M., Tatton, N. A., Wolfus, C., & Ward, M. E. (2023) · Cognitive and Behavioral Neurology · doi:10.1097/wnn.0000000000000356 · Cited by 9 · see citing works
Graviotto, H. G., Sorbara, M., Turizo-Rodriguez, C. M., & Serrano, C. M. (2022) · Dementia & Neuropsychologia · doi:10.1590/1980-5764-dn-2021-0043 · Cited by 9 · see citing works
Fieldhouse, J. L. P., van Paassen, D. N., van Engelen, M.-P. E., De Boer, S. C. M., Hartog, W. L., Braak, S., Schoonmade, L. J., Schouws, S. N. T. M., Krudop, W. A., Oudega, M. L., et al. (2024) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2024.1382593 · Cited by 8 · see citing works
Language in behavioral variant frontotemporal dementia: Another stone to be turned in Latin America
Geraudie, A., Díaz Rivera, M., Montembeault, M., & García, A. M. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.702770 · Cited by 7 · see citing works
Nevler, N., Cho, S., Cousins, K. A. Q., Ash, S., Olm, C. A., Shellikeri, S., Agmon, G., Gonzalez-Recober, C., Xie, S. X., Barker, M. S., et al. (2024) · Neurology · doi:10.1212/wnl.0000000000207926 · Cited by 7 · see citing works
Self-citationDeveloping a Memory and Communication App for Persons Living With Dementia: An 8-Step Process
Brown, E. L., Ruggiano, N., Allala, S. C., Clarke, P., Davis, D. L., Roberts, L., Framil, C. V., Muñoz, M. T. H., Hough, M. S., & Bourgeois, M. S. (2023) · JMIR Aging · doi:10.2196/44007 · Cited by 7 · see citing works
Connected Speech Alterations and Progression in Patients With Primary Progressive Aphasia Variants
Canu, E., Agosta, F., Lumaca, L., Basaia, S., Castelnovo, V., Santicioli, S., Pisano, S., Gatti, E., Lamanuzzi, A., Spinelli, E. G., et al. (2025) · Neurology · doi:10.1212/wnl.0000000000213524 · Cited by 6 · see citing works
Tröger, J., Baltes, J., Baykara, E., Kasper, E., Kring, M., Linz, N., Robin, J., Schäfer, S., Schneider, A., & Hermann, A. (2023) · Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration · doi:10.1080/21678421.2023.2239312 · Cited by 6 · see citing works
Cai, Y., Peng, Z., He, Q., & Sun, P. (2024) · BMC Medical Genomics · doi:10.1186/s12920-024-01819-5 · Cited by 6 · see citing works
Lavoie, M., Black, S. E., Tang‐Wai, D. F., Graham, N. L., Stewart, S., Freedman, M., Léonard, C., & Rochon, E. A. (2022) · Aphasiology · doi:10.1080/02687038.2022.2084707 · Cited by 5 · see citing works
Prodromal language impairment in genetic frontotemporal dementia within the GENFI cohort
Samra, K., MacDougall, A. M., Bouzigues, A., Bocchetta, M., Cash, D. M., Greaves, C. V., Convery, R. S., Swieten, J. C. V., Jiskoot, L. C., Seelaar, H., et al. (2023) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2023.120711 · Cited by 5 · see citing works
Comparing Individuals With PPA to Individuals With AD: Cognitive and Linguistic Profiles
Karpathiou, N., & Kambanaros, M. (2022) · Frontiers in Communication · doi:10.3389/fcomm.2022.893471 · Cited by 6 · see citing works
Brown, E. L., Ruggiano, N., Roberts, L., Clarke, P., Davis, D. L., Agronin, M., Geldmacher, D., Hough, M. S., Muñoz, M. H., Framil, C. V., et al. (2021) · Research in Gerontological Nursing · doi:10.3928/19404921-20210825-02 · Cited by 4 · see citing works
Baqué, L., Ayuso, M. J. M., & Santos‐Santos, M. (2022) · Revista de Neurología · doi:10.33588/rn.7402.2021197 · Cited by 4 · see citing works
Rethinking the diagnosis of primary progressive aphasia: current challenges and future directions
Macoir, J., Lavoie, M., Duboisdindien, G., & Laforce, R. J. (2025) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2025.1736855 · Cited by 3 · see citing works
Historical Review of Research in Discourse Deficits and Its Recent Advancement
Stark, B. C. (2023) · Springer eBooks · doi:10.1007/978-3-031-45190-4_1 · Cited by 3 · see citing works
Grasso, S. M., Berstis, K., Schaffer, K. M., Keegan-Rodewald, W. R., Wauters, L., Europa, E., Hubbard, H. I., Dial, H. R., Hixon, J. G., Gorno‐Tempini, M. L., et al. (2024) · Cortex · doi:10.1016/j.cortex.2024.09.019 · Cited by 2 · see citing works
Koukoulioti, V., Stavrakaki, S., Mamouli, D., & Ioannidis, P. (2024) · Applied Sciences · doi:10.3390/app14135390 · Cited by 1 · see citing works
Anwia, M. A., Lowe, M., Matis, S., Carrick, J., Piguet, O., Landin-Romero, R., & Ballard, K. (2025) · Cortex; a journal devoted to the study of the nervous system and behavior · doi:10.1016/j.cortex.2025.11.011 · Cited by 1 · see citing works
Tian, Y., & Whitwell, J. L. (2026) · NeuroImage · doi:10.1016/j.neuroimage.2026.121984 · Cited by 1 · see citing works
Haeger, A., Muising, J., Romanzetti, S., Fimm, B., Matz, O., Schulz, J. B., Heim, S., & Reetz, K. (2024) · Brain and Behavior · doi:10.1002/brb3.3420
Advances in Primary Progressive Aphasia
Matías‐Guiu, J. A., Laforce, R. J., & Utianski, R. L. (2022) · MDPI eBooks · doi:10.3390/books978-3-0365-4407-6
Park, J., Sung, J. E., & Kim, Y. T. (2023) · Eon'eo cheong'gag jang'ae yeon'gu/Communication sciences & disorders · doi:10.12963/csd.22919
Dysfluency in primary progressive aphasia: Temporal speech parameters
Baqué, L., & Ayuso, M. J. M. (2024) · Clinical Linguistics & Phonetics · doi:10.1080/02699206.2024.2378345 · Cited by 1 · see citing works
Discourse in primary progressive aphasia: Longitudinal changes and neural correlatesPreprint
Anwia, M. A., Lowe, M., Matis, S., Carrick, J., Piguet, O., Landin-Romero, R., & Ballard, K. (2025) · medRxiv · doi:10.1101/2025.05.26.25328350
Semi-spontaneous language production in Dutch-speaking individuals with primary progressive aphasia
Wets, I., Jiskoot, L. C., van den Berg, E., Janssen, N., & Piai, V. (2025) · Cognitive Neuropsychology · doi:10.1080/02643294.2025.2556493
Language in behavioral variant frontotemporal dementia
Géraudie, A., & Montembeault, M. (2025) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780198888482.013.0017
Henderson, S. K., Russell-Meill, M., Shivers, E., Sivakumar, D., & Kiran, S. (2026) · medRxiv · doi:10.64898/2026.05.14.26353233
Progression of language profiles in primary progressive aphasia: A bicentric longitudinal study
Dubos, A. M., Maso, S., Siguier, P. L. M., Deneve, A., Trogneux, L., Geraudie, A., Carpentier, C., Forestier, N., Delrutte, S., Manteaux, A., et al. (2026) · Cortex · doi:10.1016/j.cortex.2026.08.004
- Authors
- Ash, S., Nevler, N., Phillips, J., Irwin, D. J., McMillan, C. T., Rascovsky, K., & Grossman, M.
- Affiliations
- University of Pennsylvania (US)
- Corresponding author
- Ash, Sharon
- Venue
- Brain and Language
- Publisher
- Elsevier BV
- Published
- 2019-07
- Volume
- 194
- Pages
- 46-57
- ISSN
- 0093-934X (ISSN-L)
- PMC
- PMC6656376
- OpenAlex
- W2943955580
- Cited by
- 47
- References
- 71
- Citations by year
- 2026: 3 · 2025: 7 · 2024: 9 · 2023: 11 · 2022: 6 · 2021: 11
- FWCI
- 3.39
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Brain and Language (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (AG017586, AG054519, AG052943, K23NS088341, K043503)
- Institute on Aging (AG04350)
- Alzheimer’s Association (AACSF-18-567-131)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
- Health Sciences › Medicine › Neurology › Amyotrophic Lateral Sclerosis Research
- Keywords
- primary progressive aphasia, behavioral variant frontotemporal dementia, speech production, language loss, cortical thickness, gray matter atrophy, speech fluency, grammaticality, temporal cortex, neuropsychological decline
- MeSH terms
- Aged, Cerebral Cortex, Female, Humans, Longitudinal Studies, Magnetic Resonance Imaging, Male, Middle Aged, Semantics, Speech, Aphasia, Primary Progressive, Frontotemporal Dementia, Gray Matter
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
