Inhibiting NF-κB activation by small molecules as a therapeutic strategy

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

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Signaling to NF-κB

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Activators and target genes of Rel/NF-κB transcription factors

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Missing Pieces in the NF-κB Puzzle

Ghosh, S., & Karin, M. (2002) · Cell · doi:10.1016/s0092-8674(02)00703-1 · Cited by 3,638 · cited 1×

Activators and Target Genes of Rel/NF-кB Transcription Factors

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NF-κB: linking inflammation and immunity to cancer development and progression

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Multiple nuclear factors interact with the immunoglobulin enhancer sequences

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Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase

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Novel lung adenocarcinoma and nuclear factor-kappa B (NF-κB) inhibitors: Synthesis and evaluation of lantadene congeners

Suthar, S. K., Boon, H. L., & Sharma, M. (2014) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2013.12.052 · Cited by 14

Synthesis of coumaperine derivatives: Their NF-κB inhibitory effect, inhibition of cell migration and their cytotoxic activity

Nandakumar, N., Muthuraman, S., Gopinath, P., Nithya, P., Gopas, J., & Rajendran, S. (2016) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2016.10.047 · Cited by 14

Anti-survivin effect of the small molecule inhibitor YM155 in RCC cells is mediated by time-dependent inhibition of the NF-κB pathway

Sim, M. Y., Yuen, J. S. P., & Go, M. (2018) · Scientific Reports · doi:10.1038/s41598-018-28213-3 · Cited by 14

Synthetic human monoclonal antibody targets hIL1 receptor accessory protein chain with therapeutic potential in triple-negative breast cancer

Zheng, P., Zhang, Y., Zhang, B., Wang, Y., Wang, Y., & Yang, L. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.07.099 · Cited by 14

Controlling Nuclear NF-κB Dynamics by β-TrCP—Insights from a Computational Model

Benary, U., & Wolf, J. (2019) · Biomedicines · doi:10.3390/biomedicines7020040 · Cited by 13

Anti-inflammatory Activity of Etlingera elatior (Jack) R.M. Smith Flower on Gastric Ulceration-induced Wistar Rats

Juwita, T., Pakpa, W. H. P., Puspita, I. M., Saptarini, N. M., & Levita, J. (2020) · Pakistan Journal of Biological Sciences · doi:10.3923/pjbs.2020.1193.1200 · Cited by 14

Epoxyazadiradione exhibit activities in head and neck squamous cell carcinoma by targeting multiple pathways

Rai, V., Aggarwal, S. K., Verma, S. S., Awasthee, N., Dhasmana, A., Aggarwal, S., Das, S. N., Nair, M. S., Yadav, S., & Gupta, S. C. (2020) · APOPTOSIS · doi:10.1007/s10495-020-01633-1 · Cited by 14

Eriodictyol Suppresses Porphyromonas gingivalis-Induced Reactive Oxygen Species Production by Gingival Keratinocytes and the Inflammatory Response of Macrophages

Maquera-Huacho, P. M., Spolidório, D. M. P., Manthey, J. A., & Grenier, D. (2022) · Frontiers in Oral Health · doi:10.3389/froh.2022.847914 · Cited by 13

Mechanisms underlying corticosteroid resistance in patients with asthma: a review of current knowledge

Milara, J., Morell, A., Roger, I., Montero, P., & Cortijo, J. (2023) · Expert Review of Respiratory Medicine · doi:10.1080/17476348.2023.2255124 · Cited by 14

BMP1 Promotes Keloid by Inducing Fibroblast Inflammation and Fibrogenesis

Wang, Y., Chen, Y., Wu, J., & Shi, X. (2024) · Journal of Cellular Biochemistry · doi:10.1002/jcb.30609 · Cited by 15

A Cell-Specific Nuclear Factor-Kappa B–Activating Gene Expression Strategy for Delivering Cancer Immunotherapy

Wang, D., Dai, W., & Wang, J. (2018) · Human Gene Therapy · doi:10.1089/hum.2018.093 · Cited by 11

NO-Donor Nitrosyl Iron Complex with 2-Aminophenolyl Ligand Induces Apoptosis and Inhibits NF-κB Function in HeLa Cells

Stupina, T. S., Балакина, А. А., Kondrat’eva, T., Козуб, Г. И., Санина, Н. А., & Терентьев, А. А. (2018) · Scientia Pharmaceutica · doi:10.3390/scipharm86040046 · Cited by 13

CARMA3 Promotes Colorectal Cancer Cell Motility and Cancer Stemness via YAP-Mediated NF-κB Activation

Chang, T.-Y., Wu, C., Sheu, M., Yang, R., & Liu, S. (2021) · Cancers · doi:10.3390/cancers13235946 · Cited by 13

Molecular Mechanism of Curcumin and Its Analogs as Multifunctional Compounds against Pancreatic Cancer

Huang, Q., Zhang, Y., Zheng, Y., Yang, H., Yang, Y., Mo, Y., Li, L., & Zhang, H. (2022) · Nutrition and Cancer · doi:10.1080/01635581.2022.2071451 · Cited by 13

Functional Toll-like receptor 4 expressed in lactotrophs mediates LPS-induced proliferation in experimental pituitary hyperplasia

Sabatino, M. E., Sosa, L. D. V., Petiti, J. P., Mukdsi, J. H., Mascanfroni, I. D., Pellizas, C. G., Gutiérrez, S., Torres, A. I., & Paul, A. L. D. (2013) · Experimental Cell Research · doi:10.1016/j.yexcr.2013.08.012 · Cited by 13

Molecular Genetic and Epigenetic Basis of Multiple Sclerosis

Hojati, Z. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-47861-6_6 · Cited by 14

NF-kappaB Regulates Redox Status in Breast Cancer Subtypes

Pires, B. R. B., Binato, R., Ferreira, G. M., Cecchini, R., Panis, C., & Abdelhay, E. S. F. W. (2018) · Genes · doi:10.3390/genes9070320 · Cited by 13

Inflammasomes as Potential Therapeutic Targets to Prevent Chronic Active Viral Myocarditis—Translating Basic Science into Clinical Practice

Przytuła, N., Podolec, J., Przewłocki, T., Podolec, P. S., & Kabłak-Ziembicka, A. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262211003 · Cited by 12

Chemical modulation of transcription factors

Wiedemann, B. M., Weisner, J., & Rauh, D. (2018) · MedChemComm · doi:10.1039/c8md00273h · Cited by 12

The ethanolic extract of Curcuma longa grown in Korea exhibits anti-neuroinflammatory effects by activating of nuclear transcription factor erythroid-2-related factor 2/heme oxygenase-1 signaling pathway

Kim, K.-W., Lee, Y., Yoon, D., Kim, G., & Lee, D. (2022) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-022-03825-5 · Cited by 14

Non-Psychoactive Phytocannabinoids Inhibit Inflammation-Related Changes of Human Coronary Artery Smooth Muscle and Endothelial Cells

Teichmann, E., Blessing, E., & Hinz, B. (2023) · Cells · doi:10.3390/cells12192389 · Cited by 12

Microglial NOX2 as a therapeutic target in traumatic brain injury: Mechanisms, consequences, and potential for neuroprotection

Bano, N., Khan, S., Ahamad, S., Dar, N. J., Alanazi, H. H., Nazir, A., & Bhat, S. A. (2025) · Ageing Research Reviews · doi:10.1016/j.arr.2025.102735 · Cited by 13

Evaluation of the anti-inflammatory/chondroprotective activity of aldose reductase inhibitors in human chondrocyte cultures

Panico, A., Maccari, R., Cardile, V., Avondo, S., Crascì, L., & Ottanà, R. (2015) · MedChemComm · doi:10.1039/c4md00556b · Cited by 12

Tunability enhancement of gene regulatory motifs through competition for regulatory protein resources

Das, S., & Choubey, S. (2020) · Physical review. E · doi:10.1103/physreve.102.052410 · Cited by 10

Atg7 deficiency in microglia drives an altered transcriptomic profile associated with an impaired neuroinflammatory response

Frieß, L., Cheray, M., Keane, L., Grabert, K., & Joseph, B. (2021) · Molecular Brain · doi:10.1186/s13041-021-00794-7 · Cited by 11

Disabling the Nuclear Translocalization of RelA/NF-κB by a Small Molecule Inhibits Triple-Negative Breast Cancer Growth

Kanzaki, H., Chatterjee, A., Ariani, H. H. N., Zhang, X., Chung, S., Deng, N., Ramanujan, V. K., Cui, X., Greene, M. I., & Murali, R. (2021) · Breast Cancer Targets and Therapy · doi:10.2147/bctt.s310231 · Cited by 12

Supplementation of oat ( Avena sativa L.) extract abates alcohol-induced acute liver injury in a mouse model

Mir, S. M., Sahu, B. D., Koneru, M., Kuncha, M., Jerald, M. K., Ravuri, H. G., Kanjilal, S., & Sistla, R. (2018) · Nutrition Research · doi:10.1016/j.nutres.2018.04.002 · Cited by 12

Honeycomb-structured metasurfaces for the adaptive nesting of endothelial cells under hemodynamic loads

Bachmann, B. J., Giampietro, C., Bayram, A., Stefopoulos, G., Michos, C., Graeber, G., Falk, V., Dimos Poulikakos, A., & Ferrari, A. (2018) · Biomaterials Science · doi:10.1039/c8bm00660a · Cited by 13

Involvement of the NF-κB signaling pathway in proliferation and invasion inhibited by Zwint-1 deficiency in Pancreatic Cancer Cells

Kim, J. H., Youn, Y., Lee, J.-C., Kim, J., & Hwang, J. (2020) · Journal of Cancer · doi:10.7150/jca.46173 · Cited by 12

The Transcription Factor NF-κB Mediates Thyrotropin-Stimulated Expression of Thyroid Differentiation Markers

Geysels, R. C., Peyret, V., Martín, M., Nazar, M., Reale, C., Barquero, C. E. B., Miranda, L., Marti, M. A., Vito, P., Masini-Repiso, A. M., et al. (2020) · Thyroid · doi:10.1089/thy.2020.0208 · Cited by 12

Effect of Diallyl Trisulfide on TNF-α-induced CCL2/MCP-1 Release in Genetically Different Triple-negative Breast Cancer Cells

Kanga, K. J. W., MENDONCA, P., Soliman, K. F. A., Ferguson, D. T., & Darling‐Reed, S. (2021) · Anticancer Research · doi:10.21873/anticanres.15411 · Cited by 13

Transcriptional induction of NF-κB-inducing kinase by E2F4/5 facilitates collective invasion of GBM cells

Pflug, K. M., Lee, D. W., McFadden, K., Herrera, L., & Sitcheran, R. (2023) · Scientific Reports · doi:10.1038/s41598-023-38996-9 · Cited by 11

Okadaic acid enhances NfKB, TLR-4, caspase 3, ERK ½, c-FOS, and 8-OHdG signaling pathways activation in brain tissues of zebrafish larvae

Topal, A., Oğuş, H., Sulukan, E., Çomaklı, S., & Ceyhun, S. B. (2024) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2024.109529 · Cited by 11

Nitric Oxide Inhibits NF-κB-mediated Survival Signaling: Possible Role in Overcoming TRAIL Resistance

Bauer, J. A., Lupica, J. A., DiDonato, J. A., & Lindner, D. J. (2020) · Anticancer Research · doi:10.21873/anticanres.14698 · Cited by 11

Immunomodulatory effect of pentagalloyl glucose in LPS-stimulated RAW264.7 macrophages and PAO1-induced Caenorhabditis elegans

Zhang, X., Li, W., Feng, K., Xiao, J., Du, J., Cao, Y., & Chen, Y. (2021) · Experimental Gerontology · doi:10.1016/j.exger.2021.111388 · Cited by 11

The Inhibitory Effects of Vanillin on the Growth of Melanoma by Reducing Nuclear Factor-κB Activation

Pourhadi, M., Ghasemi, A., Abediny, R., Javanmard, S. H., & Vaseghi, G. (2022) · Advanced Biomedical Research · doi:10.4103/abr.abr_280_21 · Cited by 11

The spin trap 5,5-dimethyl-1-pyrroline N-oxide inhibits lipopolysaccharide-induced inflammatory response in RAW 264.7 cells

Zhai, Z., Gomez-Mejiba, S., Zhu, H., Lupu, F., & Ramírez, D. C. (2012) · Life Sciences · doi:10.1016/j.lfs.2011.12.018 · Cited by 11

Inhibitors of transcription factor nuclear factor-kappa beta (NF-κβ)-DNA binding

Sharma, R. K., Otsuka, M., Gaba, G., & Mehta, S. (2012) · RSC Advances · doi:10.1039/c2ra21852f · Cited by 11

Regulation of transcription factors by the epigallocatechin-3-gallate in poultry reared under heat stress

Şahin, K., & Smith, M. O. (2016) · World s Poultry Science Journal · doi:10.1017/s0043933916000209 · Cited by 11

X-linked Dystonia-Parkinsonism patient cells exhibit altered signaling via nuclear factor-kappa B

Vaine, C. A., Shin, D. S., Liu, C. H., Hendriks, W. T. J., Dhakal, J., Shin, K., Sharma, N., & Bragg, D. C. (2016) · Neurobiology of Disease · doi:10.1016/j.nbd.2016.12.016 · Cited by 12

Nf-κb-Dependent Inhibition of HIV-1 Transcription by Withaferin A

Shi, T., Wilhelm, E., Bell, B., & Dumais, N. (2017) · HIV Current Research · doi:10.4172/2572-0805.1000119 · Cited by 11

Anti-Müllerian Hormone Type II Receptor Expression in Endometrial Cancer Tissue

Gowkielewicz, M., Lipka, A., Majewska, M., Piotrowska, A., Szadurska-Noga, M., Nowakowski, J. J., Wiszpolska, M., Dzięgiel, P., Waśniewski, T., Majewski, M. K., et al. (2020) · Cells · doi:10.3390/cells9102312 · Cited by 11

Effects of Compounds Isolated from Lindera erythrocarpa on Anti-Inflammatory and Anti-Neuroinflammatory Action in BV2 Microglia and RAW264.7 Macrophage

Yoon, C., Lee, H., Liu, Z., Lee, H., & Lee, D. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23137122 · Cited by 11

LASSBio‐1829 Hydrochloride: Development of a New Orally Active N‐Acylhydrazone IKK2 Inhibitor with Anti‐inflammatory Properties

Guedes, I. A., de Freitas, R. H. C. N., Cordeiro, N. D. M., do Nascimento, T. S., Valerio, T. S., Fernandes, P. D., Dardenne, L. E., & Fraga, C. A. M. (2015) · ChemMedChem · doi:10.1002/cmdc.201500266 · Cited by 11

Establishment of Stable Reporter Expression for In Vivo Imaging of Nuclear Factor-κB Activation in Mouse Liver

Yan, S., Fu, Q., Zhou, Y. K., Zhang, N., Zhou, Q., Wang, X., Yuan, Z., Wang, X., Du, J., Zhang, G., et al. (2013) · Theranostics · doi:10.7150/thno.6997 · Cited by 11

Prevention of Inflammatory Disorders in the Preterm Neonate: An Update with a Special Focus on Bronchopulmonary Dysplasia

Glaser, K., Jensen, E. A., & Wright, C. J. (2024) · Neonatology · doi:10.1159/000539303 · Cited by 10

A Kinome-Wide siRNA Screen Identifies Multiple Roles for Protein Kinases in Hypoxic Stress Adaptation, Including Roles for IRAK4 and GAK in Protection against Apoptosis in VHL–/– Renal Carcinoma Cells, Despite Activation of the NF-κB Pathway

Pan, J., Zhang, J., Hill, A., LaPan, P., Berasi, S., Bates, B., Miller, C., & Haney, S. A. (2013) · SLAS DISCOVERY · doi:10.1177/1087057113484803 · Cited by 10

Clinicopathological implications of nuclear factor κB signal pathway activation in diffuse large B-cell lymphoma

Zhao, Q., Fu, W., Jiang, H., Du, J., Zhang, C., Xi, H., Zhou, F., Li, R., & Hou, J. (2014) · Human Pathology · doi:10.1016/j.humpath.2014.06.032 · Cited by 10

The Role of 2-Oxoglutarate-Dependent Oxygenases in Hypoxia Sensing

Wilkins, S. E., Flashman, E., Scotti, J. S., Hopkinson, R. J., Chowdhury, R., & Schofield, C. J. (2015) · Royal Society of Chemistry eBooks · doi:10.1039/9781782621959-00169 · Cited by 10

Tomato Powder Modulates NF-κB, mTOR, and Nrf2 Pathways during Aging in Healthy Rats

Şahin, K., Orhan, C., Tuzcu, M., Taştan, H., Bilir, B., Şahin, N., Öner, D. A., & Küçük, Ö. (2019) · Journal of Aging Research · doi:10.1155/2019/1643243 · Cited by 10

Therapeutic Role of Fibroblast Growth Factor 21 (FGF21) in the Amelioration of Chronic Diseases

Opoku, Y. K., Liu, Z., Afrifa, J., Khoso, M. H., Ren, G., & Li, D. (2019) · International Journal of Peptide Research and Therapeutics · doi:10.1007/s10989-019-09820-8 · Cited by 10

Exploring public health benefits of Dolichos lablab as a dietary supplement during the COVID-19 outbreak: A computational study

Purwanti, E., Hermanto, F. E., Souhaly, J. W., Prihanta, W., & Permana, T. I. (2021) · Journal of Applied Pharmaceutical Science · doi:10.7324/japs.2021.110217 · Cited by 12

NF-κB and Related Autoimmune and Autoinflammatory Diseases

Freigeh, G. E., & Michniacki, T. F. (2023) · Rheumatic Disease Clinics of North America · doi:10.1016/j.rdc.2023.06.008 · Cited by 10

Fetuin-B Overexpression Promotes Inflammation in Diabetic Retinopathy Through Activating Microglia and the NF-κB Signaling Pathway

Zhang, W., Yao, J., Chen, C., Wang, J., & Zhou, A. (2023) · Current Eye Research · doi:10.1080/02713683.2023.2276683 · Cited by 10

Synthesis and Biological Screening of Silicon-Containing Ibuprofen Derivatives: A Study of Their NF-?ß Inhibitory Activity, Cytotoxicity, and Their Ability to Bind IKKß

Pérez, D. J., Zakai, U. I., Guo, S., Guzei, I. A., Gómez‐Sandoval, Z., Razo‐Hernández, R. S., West, R., & Ramos-Organillo, Á. (2015) · Australian Journal of Chemistry · doi:10.1071/ch15527 · Cited by 10

An Insight into Purine, Tyrosine and Tryptophan Derived Marine Antineoplastic Alkaloids

Palkar, M. B., Rane, R. A., Thapliyal, N. B., Shaikh, M. S., Alwan, W. S., Jain, K., Karunanidhi, S., Patel, H., Hampannavar, G. A., & Karpoormath, R. V. (2015) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/1871520615666150101143520 · Cited by 10

Identification of novel NF‐κB transcriptional targets in TNFα‐treated HeLa and HepG2 cells

Zhou, F., Xu, X., Wang, D., Wu, J., & Wang, J. (2017) · Cell Biology International · doi:10.1002/cbin.10762 · Cited by 11

Study of the inhibitory effects on TNF ‐α‐induced NF ‐κB activation of IMD 0354 analogs

Li, Y., Lin, C., Huang, C., Wong, Y.-H., Hsieh, C., Wu, H., Chen, J. J. W., & Wu, Y. (2017) · Chemical Biology & Drug Design · doi:10.1111/cbdd.13032 · Cited by 10

INH14, a Small‐Molecule Urea Derivative, Inhibits the IKKα/β‐Dependent TLR Inflammatory Response

Drexel, M., Kirchmair, J., & Santos‐Sierra, S. (2018) · ChemBioChem · doi:10.1002/cbic.201800647 · Cited by 10

Replication of Crohn’s Disease Mucosal E. coli Isolates inside Macrophages Correlates with Resistance to Superoxide and Is Dependent on Macrophage NF-kappa B Activation

Tawfik, A., Knight, P., Duckworth, C. A., Pritchard, D. M., Rhodes, J. M., & Campbell, B. J. (2019) · Pathogens · doi:10.3390/pathogens8020074 · Cited by 12

C7ORF41 Regulates Inflammation by Inhibiting NF‐κB Signaling Pathway

Zhou, J., Zhou, Q., Zhang, T., & Fan, J. (2021) · BioMed Research International · doi:10.1155/2021/7413605 · Cited by 10

Neuroendocrine regulation of cholangiocarcinoma: A status quo review

Sha, M., Cao, J., Sun, H., Tong, Y., & Xia, Q. (2019) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2019.05.005 · Cited by 10

Targeting 7-ketocholesterol-induced oxidative stress and inflammation: Guggulsterone as a novel vascular protectant

Sabarathinam, S., & Ganamurali, N. (2025) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2025.106846 · Cited by 9

Moringin, an isothiocyanate modulates multiple cellular signalling molecules in breast cancer cells

Srivastava, A., Mishra, S., Avadhesh, A., Shekher, A., Rai, V., Dhasmana, A., Das, J., Perenzoni, D., Iori, R., & Gupta, S. C. (2024) · Cellular Signalling · doi:10.1016/j.cellsig.2024.111181 · Cited by 9

Effects of VitabridC12on Skin Inflammation

Lee, J. H., Jeon, Y.-J., Choi, J. H., Kim, H. Y., & Kim, T. (2017) · Annals of Dermatology · doi:10.5021/ad.2017.29.5.548 · Cited by 9

A negative feedback loop involving NF-κB/TIR8 regulates IL-1β-induced epithelial- myofibroblast transdifferentiation in human tubular cells

Jiang, K., Zhang, Y., He, F., Zhang, M., Li, T., Tu, Z., Xu, D., Zhang, M., Han, L., Guo, L., et al. (2021) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-021-00620-8 · Cited by 9

What Nutraceuticals Can Do for Duchenne Muscular Dystrophy: Lessons Learned from Amino Acid Supplementation in Mouse Models

Paepe, B. D. (2023) · Biomedicines · doi:10.3390/biomedicines11072033 · Cited by 9

Stochastic dynamics of genetic broadcasting networks

Potoyan, D. A., & Wolynes, P. G. (2017) · Physical review. E · doi:10.1103/physreve.96.052305 · Cited by 9

Investigation the mechanism of the apoptosis induced by lactacystin in gastric cancer cells

Li, Y., Gao, H., Wang, Y., & Dai, C. (2014) · Tumor Biology · doi:10.1007/s13277-014-2982-x · Cited by 8

Influence of glucosamine on the bioactivity of insulin delivered subcutaneously and in an oral nanodelivery system

Omari, M. A., Al-Kurdi, Z. I., Chowdhry, B. Z., Leharne, S. A., Qinna, N. A., & Badwan, A. A. (2015) · Drug Design Development and Therapy · doi:10.2147/dddt.s91974 · Cited by 8

The role of dendritic cells in neuroblastoma: Implications for immunotherapy

Zafari, R., Razi, S., & Rezaei, N. (2022) · Immunobiology · doi:10.1016/j.imbio.2022.152293 · Cited by 8

Exosome proteomics study of the effects of traditional cigarettes and electronic cigarettes on human bronchial epithelial cells

Weiling, W., Zeng, R., Liu, M., Chen, M., Wei, S., Li, B., & Yu, S. (2022) · Toxicology in Vitro · doi:10.1016/j.tiv.2022.105516 · Cited by 8

Synthesis and evaluation of the effects of solid lipid nanoparticles of ivermectin and ivermectin on cuprizone-induced demyelination via targeting the TRPA1/NF-kB/GFAP signaling pathway.

Noori, T., Dehpour, A. R., Alavi, S. D., Hosseini, S. Z., Korani, S., Sureda, A., Esmaeili, J., & Shirooie, S. (2023) · PubMed Central · doi:10.22038/ijbms.2023.71309.15493 · Cited by 8

Acetylharpagide Protects Mice from Staphylococcus Aureus-Induced Acute Lung Injury by Inhibiting NF-κB Signaling Pathway

Zhang, Z., Wang, Y., Shan, Y., & Wu, Y. (2020) · Molecules · doi:10.3390/molecules25235523 · Cited by 9

Building the drug-GO function network to screen significant candidate drugs for myasthenia gravis

Li, S., Cao, Y., Li, L., Zhang, H., Lu, X., Bo, C., Kong, X., Liu, Z., Chen, L., Liu, P., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0214857 · Cited by 8

Trichostatin A augments esophageal squamous cell carcinoma cells migration by inducing acetylation of RelA at K310 leading epithelia–mesenchymal transition

Huang, K., Liu, Y., Gu, C., Liu, D., & Zhao, B. (2020) · Anti-Cancer Drugs · doi:10.1097/cad.0000000000000927 · Cited by 8

Design, synthesis, and biological evaluation of potent 1,2,3,4-tetrahydroisoquinoline derivatives as anticancer agents targeting NF-κB signaling pathway

Sim, S., Lee, S., Ko, S., Bui, B. P., Nguyen, P. L., Cho, J., Lee, K., Kang, J. S., Jung, J., & Lee, H. (2021) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2021.116371 · Cited by 8

The nuclear factor kappa-B signaling pathway as a therapeutic target against thyroid cancers

Li, X., Abdel‐Mageed, A. B., Mondal, D., & Kandil, E. H. (2012) · Thyroid · doi:10.1089/thy.2012-0237 · Cited by 8

Chuanxiong-Renshen medicine pair ameliorates neuroinflammation in Alzheimer’s disease through modulation of the PKC-α/NF-κB signaling pathway

Wang, X., Wang, Y., Zhang, J., Li, Q., Yu, T., & Yang, Y. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.157161 · Cited by 7

A computational workflow for assessing drug effects on temporal signaling dynamics reveals robustness in stimulus-specific NFκB signaling

Bozich, E. R., Guo, X., Wilson, J. L., & Hoffmann, A. (2025) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1013344 · Cited by 11

Bacterial EVs contain small RNAs and transfer RNAs that regulate inflammation in lung infections

Charpentier, L. A., & Stanton, B. A. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1677190 · Cited by 8

Chlorella improves inflammatory profiles and quality of life of prediabetes and diabetes patients

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Low-level Cu-fortification of bovine lactoferrin: Focus on its effect on in vitro anti-inflammatory activity in LPS-stimulated macrophages

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