The DOI matches its Crossref record; 68 of the 68 references it cites were found in a registry or an index.
Lipid imaging with time-of-flight secondary ion mass spectrometry (ToF-SIMS)
Open accessAbstract
Fundamental advances in secondary ion mass spectrometry (SIMS) now allow for the examination and characterization of lipids directly from biological materials. The successful application of SIMS-based imaging in the investigation of lipids directly from tissue and cells are demonstrated. Common complications and technical pitfalls are discussed. In this review, we examine the use of cluster ion sources and cryogenically compatible sample handling for improved ion yields and to expand the application potential of SIMS. Methodological improvements, including pre-treating the sample to improve ion yields and protocol development for 3-dimensional analyses (i.e. molecular depth profiling), are also included in this discussion. New high performance SIMS instruments showcasing the most advanced instrumental developments, including tandem MS capabilities and continuous ion beam compatibility, are described and the future direction for SIMS in lipid imaging is evaluated.
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Cites
Basal Lipid Peroxidation in Substantia Nigra Is Increased in Parkinson's Disease
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Fast atom bombardment of solids (F.A.B.): a new ion source for mass spectrometry
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Sublimation as a method of matrix application for mass spectrometric imaging
Hankin, J. A., Barkley, R. M., & Murphy, R. C. (2007) · Journal of the American Society for Mass Spectrometry · doi:10.1016/j.jasms.2007.06.010 · Cited by 598
A concise review of mass spectrometry imaging
Amstalden van Hove, E. R., Smith, D. F., & Heeren, R. M. A. (2010) · Journal of Chromatography A · doi:10.1016/j.chroma.2010.01.033 · Cited by 416
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Mass Spectrometric Imaging of Highly Curved Membranes During Tetrahymena Mating
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Self-citationAn update of MALDI-TOF mass spectrometry in lipid research
Fuchs, B., Süß, R., & Schiller, J. (2010) · Progress in Lipid Research · doi:10.1016/j.plipres.2010.07.001 · Cited by 324
Mass Spectrometric Imaging of Lipids in Brain Tissue
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Cited by
Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis
Wood, W. G., Li, L., Müller, W. E., & Eckert, G. P. (2014) · Journal of Neurochemistry · doi:10.1111/jnc.12637 · Cited by 194
Körber, A., Anthony, I. G. M., & Heeren, R. M. A. (2025) · Analytical Chemistry · doi:10.1021/acs.analchem.4c05249 · Cited by 88
Metadata
- Authors
- Passarelli, M. K., & Winograd, N.
- Venue
- Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- Publisher
- Elsevier BV
- Published
- 2011-11
- Volume
- 1811
- Issue
- 11
- Pages
- 976-990
- ISSN
- 1388-1981 (ISSN-L)
- OpenAlex
- W2077692714
- Cited by
- 314
- References
- 68
- FWCI
- 24.84
- Type
- journal article
- Language
- en
- Open access
- green
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- Passarelli, M. K., & Winograd, N. (2011). Lipid imaging with time-of-flight secondary ion mass spectrometry (ToF-SIMS). Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. https://doi.org/10.1016/j.bbalip.2011.05.007
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
