The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Surface LDLR is a major receptor for lipoprotein(a) clearance in male mice lacking PCSK9
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“Although mice do not produce endogenous Lp(a), studies of their catabolism of exogenous human Lp(a) have also yielded mixed results, with some demonstrating LDLR-dependent35,36 and some LDLR-independent25,32 clearance.”
From Functional interrogation of cellular Lp(a) uptake by genome-scale CRISPR screening (2025) · cites this paper as [36]
Citations
Cites
Lipoprotein (a): truly a direct prothrombotic factor in cardiovascular disease?
Boffa, M. B., & Koschinsky, M. L. (2016) · Journal of Lipid Research · doi:10.1194/jlr.r060582 · Cited by 309
Self-citationRoubtsova, A., Garçon, D., Lacoste, S., Chamberland, A., Marcinkiewicz, J., Métivier, R., Sotin, T., Paquette, M., Bernard, S., Cariou, B., et al. (2022) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2022.159217 · Cited by 22
Self-citation
Research works printed but not linked: 15
- Pare, 2019, Lipoprotein(a) levels and the risk of myocardial infarction among 7 ethnic groups, Circulation, 139, 1472, 10.1161/CIRCULATIONAHA.118.034311 · DOI
- McKenney, 2012, Safety and efficacy of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 serine protease, SAR236553/REGN727, in patients with primary hypercholesterolemia receiving ongoing stable atorvastatin therapy, J. Am. Coll. Cardiol., 59, 2344, 10.1016/j.jacc.2012.03.007 · DOI
- Raal, 2014, Reduction in lipoprotein(a) with PCSK9 monoclonal antibody evolocumab (AMG 145): a pooled analysis of more than 1,300 patients in 4 phase II trials, J. Am. Coll. Cardiol., 63, 1278, 10.1016/j.jacc.2014.01.006 · DOI
- Seidah, 2022, The multifaceted biology of PCSK9, Endocr. Rev., 43, 558, 10.1210/endrev/bnab035 · DOI · Paper page
- Zaid, 2008, Proprotein convertase subtilisin/kexin type 9 (PCSK9): hepatocyte-specific low-density lipoprotein receptor degradation and critical role in mouse liver regeneration, Hepatology, 48, 646, 10.1002/hep.22354 · DOI · Paper page
- Romagnuolo, 2015, Lipoprotein(a) catabolism is regulated by proprotein convertase subtilisin/kexin type 9 through the low density lipoprotein receptor, J. Biol. Chem., 290, 11649, 10.1074/jbc.M114.611988 · DOI · Paper page
- Romagnuolo, 2017, Roles of the low density lipoprotein receptor and related receptors in inhibition of lipoprotein(a) internalization by proprotein convertase subtilisin/kexin type 9, PLoS ONE, 12, 10.1371/journal.pone.0180869 · DOI
- Koschinsky, 1991, Apolipoprotein(a): expression and characterization of a recombinant form of the protein in mammalian cells, Biochemistry, 30, 5044, 10.1021/bi00234a029 · DOI
- Roubtsova, 2015, PCSK9 deficiency unmasks a sex/tissue-specific subcellular distribution of the LDL and VLDL receptors in mice, J. Lipid Res., 56, 2133, 10.1194/jlr.M061952 · DOI · Paper page
- Cain, 2005, Lipoprotein [a] is cleared from the plasma primarily by the liver in a process mediated by apolipoprotein [a], J. Lipid Res., 46, 2681, 10.1194/jlr.M500249-JLR200 · DOI · Paper page
- Hofmann, 1990, Overexpression of human low density lipoprotein receptors leads to accelerated catabolism of Lp(a) lipoprotein in transgenic mice, J. Clin. Invest., 85, 1542, 10.1172/JCI114602 · DOI · Paper page
- Reyes-Soffer, 2017, Effects of PCSK9 inhibition with alirocumab on lipoprotein metabolism in healthy humans, Circulation, 135, 352, 10.1161/CIRCULATIONAHA.116.025253 · DOI · Paper page
- Ying, 2022, PCSK9 inhibition with alirocumab decreases plasma lipoprotein(a) concentration by a dual mechanism of action in statin-treated patients with very high apolipoprotein(a) concentration, J. Intern. Med., 291, 870, 10.1111/joim.13457 · DOI
- Cordero, 2022, Sex differences in low-density lipoprotein cholesterol reduction with PCSK9 inhibitors in real-world patients: the LIPID-REAL registry, J. Cardiovasc. Pharmacol., 79, 523, 10.1097/FJC.0000000000001205 · DOI
- Sever, 2021, LDL-cholesterol lowering with evolocumab, and outcomes according to age and sex in patients in the FOURIER trial, Eur. J. Prev. Cardiol., 28, 805, 10.1177/2047487320902750 · DOI
Cited by
Sorted by citations
Functional interrogation of cellular Lp(a) uptake by genome-scale CRISPR screening
Khan, T. G., Bragazzi Cunha, J., Raut, C., Burroughs, M., Vyas, H. S., Leix, K., Goonewardena, S. N., Smrcka, A. V., Speliotes, E. K., & Emmer, B. T. (2025) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2025.119174 · Cited by 6
Metadata
- Authors
- Roubtsova, A., Scipione, C. A., Garçon, D., Boffa, M. B., Seidah, N. G., Koschinsky, M. L., & Prat, A.
- Venue
- Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- Publisher
- Elsevier BV
- Published
- 2023-04
- Volume
- 1868
- Issue
- 4
- Pages
- 159288
- ISSN
- 1388-1981
- Cited by
- 5
- References
- 2
- Language
- en
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