The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Synthetic antibiofilm peptides
Open accessAbstract
Bacteria predominantly exist as multicellular aggregates known as biofilms that are associated with at least two thirds of all infections and exhibit increased adaptive resistance to conventional antibiotic therapies. Therefore, biofilms are major contributors to the global health problem of antibiotic resistance, and novel approaches to counter them are urgently needed. Small molecules of the innate immune system called host defense peptides (HDPs) have emerged as promising templates for the design of potent, broad-spectrum antibiofilm agents. Here, we review recent developments in the new field of synthetic antibiofilm peptides, including mechanistic insights, synergistic interactions with available antibiotics, and their potential as novel antimicrobials against persistent infections caused by biofilms. This article is part of a Special Issue entitled: Antimicrobial peptides edited by Karl Lohner and Kai Hilpert.
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Citations
Cites
Bacterial Biofilms: A Common Cause of Persistent Infections
Costerton, J. W., Stewart, P. S., & Greenberg, E. P. (1999) · Science · doi:10.1126/science.284.5418.1318 · Cited by 12,167
Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?
Brogden, K. A. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1098 · Cited by 5,829
An anti-infective peptide that selectively modulates the innate immune response
Scott, M. G., Dullaghan, E., Mookherjee, N., Glavas, N., Waldbrook, M., Thompson, A., Wang, A., Lee, K., Doria, S., Hamill, P., et al. (2007) · Nature Biotechnology · doi:10.1038/nbt1288 · Cited by 403
Self-citation
Cited by
Antimicrobial host defence peptides: functions and clinical potential
Mookherjee, N., Anderson, M. A., Haagsman, H. P., & Davidson, D. J. (2020) · Nature Reviews Drug Discovery · doi:10.1038/s41573-019-0058-8 · Cited by 1,502
Mechanisms of Action for Antimicrobial Peptides With Antibacterial and Antibiofilm Functions
Raheem, N., & Straus, S. K. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.02866 · Cited by 369
Reassessing the Host Defense Peptide Landscape
Haney, E. F., Straus, S. K., & Hancock, R. E. W. (2019) · Frontiers in Chemistry · doi:10.3389/fchem.2019.00043 · Cited by 359
Self-citationAction of Antimicrobial Peptides against Bacterial Biofilms
Yasir, M., Willcox, M. D. P., & Dutta, D. (2018) · Materials · doi:10.3390/ma11122468 · Cited by 319
Antimicrobial and Antibiofilm Peptides
Di Somma, A., Moretta, A., Canè, C., Cirillo, A., & Duilio, A. (2020) · Biomolecules · doi:10.3390/biom10040652 · Cited by 258
Metadata
- Authors
- de la Fuente-Núñez, C., Cardoso, M. H., de Souza Cândido, E., Franco, O. L., & Hancock, R. E. W.
- Venue
- Biochimica et Biophysica Acta (BBA) - Biomembranes
- Publisher
- Elsevier BV
- Published
- 2016-05
- Volume
- 1858
- Issue
- 5
- Pages
- 1061-1069
- ISSN
- 0005-2736 (ISSN-L)
- OpenAlex
- W2206136994
- Cited by
- 214
- References
- 3
- FWCI
- 10.52
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- de la Fuente-Núñez, C., Cardoso, M. H., de Souza Cândido, E., Franco, O. L., & Hancock, R. E. W. (2016). Synthetic antibiofilm peptides. Biochimica et Biophysica Acta (BBA) - Biomembranes. https://doi.org/10.1016/j.bbamem.2015.12.015
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