A comprehensive overview of exosomes as drug delivery vehicles — Endogenous nanocarriers for targeted cancer therapy

Johnsen, Kasper Bendix, Gudbergsson, Johann Mar, Skov, Martin Najbjerg, Pilgaard, Linda, Moos, Torben, Duroux, Meg·2014·Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Cited by (703)

Items 301–400 of 703

  1. Exosomes in Cancer Disease
    Margot Zöller · 2015 · Methods in molecular biology
  2. Janus-Faced Myeloid-Derived Suppressor Cell Exosomes for the Good and the Bad in Cancer and Autoimmune Disease
    Margot Zöller · 2018 · Frontiers in Immunology
  3. Challenges in the Development of Drug Delivery Systems Based on Small Extracellular Vesicles for Therapy of Brain Diseases
    Loch-Neckel, Gecioni, Matos, Ana Teresa, Vaz, Ana Rita, Brites, Dora · 2022 · Frontiers in Pharmacology
  4. Targeted si-RNA with liposomes and exosomes (extracellular vesicles): How to unlock the potential
    Sophia G. Antimisiaris, Spyridon Mourtas, Κωνσταντίνα Παπαδιά · 2017 · International Journal of Pharmaceutics
  5. Extracellular Vesicles in Neurodegenerative Diseases: A Double-Edged Sword
    Ji Yong Lee, Han-Soo Kim · 2017 · Tissue Engineering and Regenerative Medicine
  6. An updated review on exosomes: biosynthesis to clinical applications
    Sheela Modani, Devendrasingh Tomar, Suma Tangirala, Anitha Sriram, Neelesh Kumar Mehra, Rahul Kumar, Dharmendra Kumar Khatri, Pankaj Kumar Singh · 2021 · Journal of drug targeting
  7. Expanding the toolbox of exosome-based modulators of cell functions
    Qinqin Cheng, Zhefu Dai, Xiaojing Shi, Xinping Duan, Yiling Wang, Tianling Hou, Yong Zhang · 2021 · Biomaterials
  8. The emerging roles of extracellular vesicles as intercellular messengers in liver physiology and pathology
    Youngseok Lee, Jong‐Hoon Kim · 2022 · Clinical and Molecular Hepatology
  9. Extracellular vesicles derived from Plasmodium-infected and non-infected red blood cells as targeted drug delivery vehicles
    Lívia Neves Borgheti-Cardoso, Sander A. A. Kooijmans, Lucía Gutiérrez-Chamorro, Arnau Biosca, Elena Lantero, Miriam Ramírez, Yunuen Avalos‐Padilla, Isabel Crespo, Irene Fernández, Carmen Fernández-Becerra et al. · 2020 · International Journal of Pharmaceutics
  10. Role of chemokines in hepatocellular carcinoma (Review)
    Dongdong Xue, Ya Zheng, Junye Wen, Jingzhao Han, Hongfang Tuo, Yifan Liu, Yanhui Peng · 2020 · Oncology Reports
  11. Exosomes: Insights and therapeutic applications in cancer
    Anita Raj Panigrahi, Srinivas Lankalapalli, Jagadeesh Panda · 2022 · Translational Oncology
  12. New insights of engineering plant exosome-like nanovesicles as a nanoplatform for therapeutics and drug delivery
    Shafiu A. Umar Shinge, Yin Xiao, Jiang Xia, Yujie Liang, Li Duan · 2022 · Extracellular Vesicles and Circulating Nucleic Acids
  13. Pathophysiological Role and Potential Therapeutic Exploitation of Exosomes in Ovarian Cancer
    Aasa Shimizu, Kenjiro Sawada, Tadashi Kimura · 2020 · Cells
  14. Exosomes: Structure, Biogenesis, Types and Application in Diagnosis and Gene and Drug Delivery
    Shriya Agarwal, Vinayak Agarwal, Mugdha Agarwal, Manisha Singh · 2020 · Current Gene Therapy
  15. Dysfunction of the Neurovascular Unit in Ischemic Stroke: Highlights on microRNAs and Exosomes as Potential Biomarkers and Therapy
    Timea Forró, Zoltán Bajkó, Adrian Florian Bălașa, Rodica Bălașa · 2021 · International Journal of Molecular Sciences
  16. Interest of extracellular vesicles in regards to lipid nanoparticle based systems for intracellular protein delivery
    Sarah Le Saux, Anne Aubert‐Pouëssel, Khaled Elhady Mohamed, Pierre Martineau, Laurence Guglielmi, Jean‐Marie Devoisselle, Philippe Legrand, Joël Chopineau, Marie Morille · 2021 · Advanced Drug Delivery Reviews
  17. Targeting Capabilities of Native and Bioengineered Extracellular Vesicles for Drug Delivery
    Liubov Frolova, Isaac T. S. Li · 2022 · Bioengineering
  18. Cancer-associated fibroblast-derived exosome microRNA-21 promotes angiogenesis in multiple myeloma
    Miaomiao Sun, Wang Xiao-qian, Yuwei Shou, Chen Chao, Chenbo Yang, Yinghao Liang, Yichen Hong, Shu Jiao, Chen Kuisheng · 2023 · Scientific Reports
  19. Enhanced therapeutic effect of PEDF-loaded mesenchymal stem cell-derived small extracellular vesicles against oxygen-induced retinopathy through increased stability and penetrability of PEDF
    Ruiyan Fan, Lin Su, Hui Zhang, Yilin Jiang, Zihao Yu, Xiaomin Zhang, Xiaorong Li · 2023 · Journal of Nanobiotechnology
  20. The application of extracellular vesicles in orthopedic diseases
    Yuexin Li, Haiyan Zhang, Yu Jiang, Jian Yang, Daozhang Cai, Xiaochun Bai · 2024 · Interdisciplinary medicine
  21. Pathological Effects of Exosomes in Mediating Diabetic Cardiomyopathy
    Esam Salem, Guo‐Chang Fan · 2017 · Advances in experimental medicine and biology
  22. Small extracellular vesicles containing miR-30a-3p attenuate the migration and invasion of hepatocellular carcinoma by targeting SNAP23 gene
    Chengdong Liu, Xiaohan Zhou, Long Qian, Hanyi Zeng, Qingcan Sun, Yuting Chen, Dehua Wu, Li Liu · 2020 · Oncogene
  23. Nanoapproaches to Modifying Epigenetics of Epithelial Mesenchymal Transition for Treatment of Pulmonary Fibrosis
    Melissa E. Skibba, Adam J. Drelich, Michael J. Poellmann, Seungpyo Hong, Allan R. Brasier · 2020 · Frontiers in Pharmacology
  24. The Role of Melanoma Cell-Derived Exosomes (MTEX) and Photodynamic Therapy (PDT) within a Tumor Microenvironment
    Bridgette Mkhobongo, Rahul Chandran, Heidi Abrahamse · 2021 · International Journal of Molecular Sciences
  25. Extracellular vesicle characteristics in stored red blood cell concentrates are influenced by the method of detection
    Ruqayyah J. Almizraq, Jerard Seghatchian, Jelena L. Holovati, Jason P. Acker · 2017 · Transfusion and Apheresis Science
  26. Milk/colostrum exosomes: A nanoplatform advancing delivery of cancer therapeutics
    Margaret Wallen, Farrukh Aqil, Wendy A. Spencer, Ramesh C. Gupta · 2023 · Cancer Letters
  27. The Opportunities and Challenges of Mesenchymal Stem Cells-Derived Exosomes in Theranostics and Regenerative Medicine
    Sachin Yadav, Priti Prasanna Maity, Kausik Kapat · 2024 · Cells
  28. MicroRNAs and altered metabolism of clear cell renal cell carcinoma: Potential role as aerobic glycolysis biomarkers
    Mariana Morais, Francisca Dias, Ana Luísa Teixeira, Rui Medeiros · 2017 · Biochimica et Biophysica Acta (BBA) - General Subjects
  29. Ginsenoside Rg3 Prevents Oxidative Stress-Induced Astrocytic Senescence and Ameliorates Senescence Paracrine Effects on Glioblastoma
    Jingang Hou, Sunchang Kim, Chang Keun Sung, Chulhee Choi · 2017 · Molecules
  30. Concise Review: Biomimetic Functionalization of Biomaterials to Stimulate the Endogenous Healing Process of Cartilage and Bone Tissue
    Francesca Taraballi, Guillermo Bauza, Patrick C. McCulloch, Joshua David Harris, Ennio Tasciotti · 2017 · Stem Cells Translational Medicine
  31. Extraction and identification of synovial tissue-derived exosomes by different separation techniques
    Pu Chen, Anmin Ruan, Jun Zhou, Liuwei Huang, Xiaozhe Zhang, Yufeng Ma, Qingfu Wang · 2020 · Journal of Orthopaedic Surgery and Research
  32. Recent Advancement and Technical Challenges in Developing Small Extracellular Vesicles for Cancer Drug Delivery
    Tianjiao Geng, Patrick Pan, Euphemia Yee Leung, Qi Chen, Larry Chamley, Zimei Wu · 2021 · Pharmaceutical Research
  33. Responsive Exosome Nano‐bioconjugates for Synergistic Cancer Therapy
    Weidong Nie, Guanghao Wu, Jinfeng Zhang, Li‐Li Huang, Jingjing Ding, Anqi Jiang, Yahui Zhang, Yanhong Liu, Jing Li, Kanyi Pu et al. · 2019 · Angewandte Chemie
  34. Progress in the application of exosomes as therapeutic vectors in tumor-targeted therapy
    Xudong Xie, Hongpei Wu, Mei Li, Xiaojun Chen, XU Xiao-yun, Wenkai Ni, Cuihua Lu, Runzhou Ni, Baijun Bao, Mingbing Xiao · 2019 · Cytotherapy
  35. Small extracellular vesicles as tumor biomarkers for glioblastoma
    Keon Mahmoudi, Alan M. Ezrin, Costas G. Hadjipanayis · 2015 · Molecular Aspects of Medicine
  36. Impact of Exosomes Released by Different Corneal Cell Types on the Wound Healing Properties of Human Corneal Epithelial Cells
    Desjardins, Pascale, Berthiaume, Rébecca, Couture, Camille, Le-Bel, Gaëtan, Roy, Vincent, Gros-Louis, François, Moulin, Véronique J., Proulx, Stéphanie, Chemtob, Sylvain, Germain, Lucie et al. · 2022 · International Journal of Molecular Sciences
  37. Pancreatic Cancer Exosomes: Shedding Off for a Meaningful Journey
    Girijesh Kumar Patel, Mary C. Patton · 2016 · Pancreatic Disorders and Therapy
  38. Glioblastoma Exosomes for Therapeutic Angiogenesis in Peripheral Ischemia
    Anthony J. Monteforte, Brian Lam, Michael B. Sherman, Kayla Henderson, Andrew D. Sligar, Adrianne Spencer, Brian Tang, Andrew K. Dunn, Aaron B. Baker · 2017 · Tissue Engineering Part A
  39. Exosomes—Small Players, Big Sound
    Diana Gulei, Alexandra Iulia Irimie, Roxana Cojocneanu, Joachim Ludwig Schultze, Ioana Berindan‐Neagoe · 2018 · Bioconjugate Chemistry
  40. Autologous Exosome Transfer: A New Personalised Treatment Concept to Prevent Colitis in a Murine Model
    Chunhua Yang, Mingzhen Zhang, Junsik J. Sung, Lixin Wang, Yunjin Jung, Didier Merlin · 2019 · Journal of Crohn s and Colitis
  41. Use of exosomes as vectors to carry advanced therapies
    María Sancho‐Albero, Ana Medel-Martínez, Pilar Martín‐Duque · 2020 · RSC Advances
  42. Exosomal ncRNAs in liquid biopsies for lung cancer
    Md Sadique Hussain, Gaurav Gupta, Nehmat Ghaboura, Ehssan H. O. Moglad, Waleed Hassan Almalki, Sami Ibrahim Alzarea, Imran Ahmed Kazmi, Haider Ali, Ronan J. MacLoughlin, Raimar Löebenberg et al. · 2024 · Clinica Chimica Acta
  43. Comparison of two endogenous delivery agents in cancer therapy: Exosomes and ferritin
    Le Li, Lianbing Zhang, Mato Knez · 2016 · Pharmacological Research
  44. Exosomes: Carriers of Pro-Fibrotic Signals and Therapeutic Targets in Fibrosis
    Mengyu Li, Mao Jiang, Jie Meng, Lijian Tao · 2019 · Current Pharmaceutical Design
  45. Brain Microvascular Endothelial Cell Derived Exosomes Potently Ameliorate Cognitive Dysfunction by Enhancing the Clearance of Aβ Through Up-Regulation of P-gp in Mouse Model of AD
    Junlu Pan, Ruyi He, Qinghao Huo, Yijie Shi, Liang Zhao · 2020 · Neurochemical Research
  46. Emerging biosensing platforms for quantitative detection of exosomes as diagnostic biomarkers
    Jiayi Tan, Yu Wen, Ming Li · 2021 · Coordination Chemistry Reviews
  47. Mycobacterium tuberculosis extracellular vesicles: exploitation for vaccine technology and diagnostic methods
    Roghayeh Mohammadzadeh, Kiarash Ghazvini, Hadi Farsiani, Saman Soleimanpour · 2020 · Critical Reviews in Microbiology
  48. Analyses of chemical components and their functions in single species plant-derived exosome like vesicle
    Si-Si Zhou, Yu Cao, Fanshu Shan, Pu-Zhen Huang, Yao Yang, Song-Qin Liu · 2023 · Trends in Analytical Chemistry (TrAC)
  49. Extracellular Vesicles: A New Perspective in Tumor Therapy
    Yanzi Sun, Junshan Ruan, Zongsheng Jiang, Ling Wang, Shaoming Wang · 2018 · BioMed Research International
  50. The therapeutic triad of extracellular vesicles: As drug targets, as drugs, and as drug carriers
    Milad Moloudizargari, Mohammad Hossein Asghari, Ajay Goel · 2021 · Biochemical Pharmacology
  51. Can the administration of platelet lysates to the brain help treat neurological disorders?
    Ouada Nebie, L. Buée, David Blum, T. Burnouf · 2022 · Cellular and Molecular Life Sciences
  52. Exosomes as Anticancer Drug Delivery Vehicles: Prospects and Challenges
    Yubo Zhang, Jian Li, Wei Gao, Na Xie · 2022 · Frontiers in Bioscience-Landmark
  53. Macrophage cell-derived exosomes/staphylococcal enterotoxin B against fibrosarcoma tumor
    Elham Behzadi, Hamideh Mahmoodzadeh Hosseini, Raheleh Halabian, Abbas Ali Imani Fooladi · 2017 · Microbial Pathogenesis
  54. Milk-derived Extracellular Vesicles for Therapeutic Delivery of Small Interfering RNAs
    Akiko Matsuda, Tushar C. Patel · 2018 · Methods in molecular biology
  55. Exosomes: Fighting Cancer With Cancer
    Hanin Alyamani, Mohammad A. Obeid, Rothwelle J. Tate, Valerie Anne Ferro · 2018 · Therapeutic Delivery
  56. A new level of complexity in parasite-host interaction: The role of extracellular vesicles
    Maibritt Mardahl, Anne Borup, Peter Lindberg Nejsum · 2019 · Advances in Parasitology/Advances in parasitology
  57. EVs delivery of miR-1915-3p improves the chemotherapeutic efficacy of oxaliplatin in colorectal cancer
    Zhenhuan Xiao, Yun Liu, Qun Li, Qinyuan Liu, Yong Liu, Yan Luo, Songzhi Wei · 2021 · Cancer Chemotherapy and Pharmacology
  58. A tumorsphere model of glioblastoma multiforme with intratumoral heterogeneity for quantitative analysis of cellular migration and drug response
    Johann Mar Gudbergsson, Serhii Kostrikov, Kasper Bendix Johnsen, Frederikke P. Fliedner, Christian Brøgger Stolberg, Nanna Humle, Anders E. Hansen, Bjarne Winther Kristensen, Gunna Christiansen, Andreas Kjær et al. · 2019 · Experimental Cell Research
  59. Exosomes for CRISPR-Cas9 Delivery: The Cutting Edge in Genome Editing
    Cynthia Aslan, Naime Majidi Zolbanin, Fatemeh Faraji, Reza Jafari · 2023 · Molecular Biotechnology
  60. Harnessing exosomes for targeted drug delivery systems to combat brain cancer
    Abdullah E Basyoni, Amira Atta, Maha M. Salem, Tarek Mostafa Mohamed · 2025 · Cancer Cell International
  61. Toward a world of theranostic medication: Programming biological sentinel systems for therapeutic intervention
    Ryosuke Kojima, Dominique Aubel, Martin Fussenegger · 2016 · Advanced Drug Delivery Reviews
  62. Nanoparticles and Their Applications
    Seyedsina Moeinzadeh, Esmaiel Jabbari · 2017 · Springer handbooks
  63. Delivery systems for theranostics in neurodegenerative diseases
    Yan Li, Ruiyuan Liu, Weihong Ji, Yanhui Li, Linying Liu, Xin Zhang · 2018 · Nano Research
  64. Managing efficacy and toxicity of drugs: Targeted delivery and excretion
    Pronab Kundu, Sinjan Das, Nitin Chattopadhyay · 2019 · International Journal of Pharmaceutics
  65. Potential Therapeutic Applications and Developments of Exosomes in Parkinson’s Disease
    Siqi Luo, Libo Du, Yan Cui · 2020 · Molecular Pharmaceutics
  66. Extracellular Vesicles as a Neprilysin Delivery System Memory Improvement in Alzheimer's Disease.
    Mehrnaz Izadpanah, Leila Dargahi, Jafar Ai, Afsaneh Asgari Taei, Somayeh Ebrahimi Barough, Seyed Javad Mowla, Gholamreza Tavoosidana, Maryam Farahmandfar · 2020 · PubMed Central
  67. Insulator Based Dielectrophoresis: Micro, Nano, and Molecular Scale Biological Applications
    Prateek Benhal, David Quashie, Y. Kim, Jamel Ali · 2020 · Sensors
  68. Synthetic Vehicles for Encapsulation and Delivery of CRISPR/Cas9 Gene Editing Machinery
    Valentina Carboni, Carine Maaliki, Mram Alyami, Shahad K. Alsaiari, Niveen M. Khashab · 2019 · Advanced Therapeutics
  69. Therapeutic Application of Small Extracellular Vesicles (sEVs): Pharmaceutical and Pharmacokinetic Challenges
    Yoshinobu Takakura, A. Matsumoto, Yuki Takahashi · 2020 · Biological and Pharmaceutical Bulletin
  70. Extracellular Vesicles Derived from Mesenchymal Stromal Cells Delivered during Hypothermic Oxygenated Machine Perfusion Repair Ischemic/Reperfusion Damage of Kidneys from Extended Criteria Donors
    Teresa Rampino, Marilena Gregorini, Giuliana Germinario, Eleonora Francesca Pattonieri, Fulvia Erasmi, Maria Antonietta Grignano, Stefano Bruno, Esra’a Alomari, Stefano Bettati, Annalia Asti et al. · 2022 · Biology
  71. Black phosphorus biomaterials for photo-controlled bone tissue engineering
    Lu Tan, Menghuan Li, Zhong Yuan Luo, Kaiyong Cai, Yan Hu · 2022 · Composites Part B Engineering
  72. Exosome drug delivery through the blood–brain barrier: experimental approaches and potential applications
    Druzhkova, T. A., Yakovlev, A. A. · 2018 · Neurochemical Journal
  73. Effective Refractive Index and Lipid Content of Extracellular Vesicles Revealed Using Optical Waveguide Scattering and Fluorescence Microscopy
    Déborah L. M. Rupert, Mokhtar Mapar, Ganesh Vilas Shelke, Karin Norling, Mathias Elmeskog, Jan O. Lötvall, Stephan Block, Marta Bally, Björn Agnarsson, Fredrik Höök · 2018 · Langmuir
  74. Exosomes as drug carriers for clinical application
    Cuixia Di, Qianjing Zhang, Yupei Wang, Fang Wang, Yuhong Chen, Lu Gan, Rong Zhou, Chao Sun, Hongyan Li, Xuetian Zhang et al. · 2018 · Artificial Cells Nanomedicine and Biotechnology
  75. Insights Into Extracellular Vesicles as Biomarker of NAFLD Pathogenesis
    Irma García‐Martinez, Rosa Alén, Patricia Rada, Ángela M. Valverde · 2020 · Frontiers in Medicine
  76. Immunoregulatory Roles of Extracellular Vesicles and Associated Therapeutic Applications in Lung Cancer
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  77. Stem Cell-Derived Exosomes Potential Therapeutic Roles in Cardiovascular Diseases
    Selvaraj Jayaraman, Dhanavathy Gnanasampanthapandian, Johnson Rajasingh, Kanagaraj Palaniyandi · 2021 · Frontiers in Cardiovascular Medicine
  78. Therapeutic Effects of Hypoxic and Pro-Inflammatory Priming of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Inflammatory Arthritis
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  79. Biochemistry of exosomes and their theranostic potential in human diseases
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  80. Therapeutic Potential of Nucleic Acids when Combined with Extracellular Vesicles
    Brian J. Jurgielewicz, Steven L. Stice, Yao Yao · 2021 · Aging and Disease
  81. Exosome-driven nano-immunotherapy: revolutionizing colorectal cancer treatment
    Masoud Lahouty, Manouchehr Fadaee, Dariush Shanehbandi, Tohid Kazemi · 2024 · Molecular Biology Reports
  82. A review on the biotechnological aspects of utilizing engineered nanoparticles as delivery systems in plants
    Indrani Manna, Maumita Bandyopadhyay · 2018 · Plant Gene
  83. Direct Drug Targeting into Intracellular Compartments: Issues, Limitations, and Future Outlook
    Gamaleldin I. Harisa, Tarek M. Faris · 2019 · The Journal of Membrane Biology
  84. Exosomes as Carriers for Antitumor Therapy
    Yanyan Li, Yongtai Zhang, Zhe Li, Kuan Zhou, Nianping Feng · 2019 · ACS Biomaterials Science & Engineering
  85. CAR (CARSKNKDC) Peptide Modified ReNcell-Derived Extracellular Vesicles as a Novel Therapeutic Agent for Targeted Pulmonary Hypertension Therapy
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  86. Recent Progress on Exosomes in RNA Virus Infection
    Liying Zhang, Yichen Ju, Si Emma Chen, Linzhu Ren · 2021 · Viruses
  87. Effects of exosomal miRNAs in the diagnosis and treatment of Alzheimer’s disease
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  88. Polymer Therapeutics: Biomarkers and New Approaches for Personalized Cancer Treatment
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  89. Exosomes in Atherosclerosis, a Double-Edged Sword: Their Role in Disease Pathogenesis and Their Potential as Novel Therapeutics
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  90. Recent advances to address challenges in extracellular vesicle-based applications for lung cancer
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  91. Exosomes and mimics as novel delivery platform for cancer therapy
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  92. Sonication is a suitable method for loading nanobody into glioblastoma small extracellular vesicles
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  93. Placenta-targeted Treatment Strategies for Preeclampsia and Fetal Growth Restriction: An Opportunity and Major Challenge
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  94. Exosome-based therapeutics in bone regeneration: from fundamental biology to clinical translation
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  95. Current approaches and prospective drug targeting to brain
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  98. Methods for the Determination of the Purity of Exosomes
    Katarzyna Kluszczyńska, Liliana Czernek, Wojciech Cypryk, Łukasz Pęczek, Markus Düchler · 2019 · Current Pharmaceutical Design
  99. Human megakaryocytic microparticles induce de novo platelet biogenesis in a wild-type murine model
    Christian Escobar, Chen‐Yuan Kao, Samik Das, Eleftherios Terry Papoutsakis · 2020 · Blood Advances
  100. Paper-based biosensors as point-of-care diagnostic devices for the detection of cancers: a review of innovative techniques and clinical applications
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