A comprehensive overview of exosomes as drug delivery vehicles — Endogenous nanocarriers for targeted cancer therapy

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

Valadi, H., Ekström, K., Bossios, A., Sjöstrand, M., Lee, J. J., & Lötvall, J. O. (2007) · Nature Cell Biology · doi:10.1038/ncb1596 · Cited by 12,834

Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review

Maeda, H., Wu, J., Sawa, T., Matsumura, Y., & Hori, K. (2000) · Journal of Controlled Release · doi:10.1016/s0168-3659(99)00248-5 · Cited by 6,565

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

Skog, J., Würdinger, T., van Rijn, S., Meijer, D. H., Gainche, L., Curry, W. T., Carter, B. S., Krichevsky, A. M., & Breakefield, X. O. (2008) · Nature Cell Biology · doi:10.1038/ncb1800 · Cited by 5,001

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

Alvarez-Erviti, L., Seow, Y., Yin, H., Betts, C., Lakhal, S., & Wood, M. J. A. (2011) · Nature Biotechnology · doi:10.1038/nbt.1807 · Cited by 4,930

Membrane vesicles as conveyors of immune responses

Théry, C., Ostrowski, M., & Segura, É. (2009) · Nature reviews. Immunology · doi:10.1038/nri2567 · Cited by 3,996

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

Trajković, K., Hsu, C., Chiantia, S., Rajendran, L., Wenzel, D., Wieland, F., Schwille, P., Brügger, B., & Simons, M. (2008) · Science · doi:10.1126/science.1153124 · Cited by 3,760

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

Peinado, H., Alečković, M., Lavotshkin, S., Matei, I., Costa-Silva, B., Moreno-Bueno, G., Hergueta-Redondo, M., Williams, C., García-Santos, G., Ghajar, C. M., et al. (2012) · Nature Medicine · doi:10.1038/nm.2753 · Cited by 3,715

Strategies in the design of nanoparticles for therapeutic applications

Petros, R. A., & DeSimone, J. M. (2010) · Nature Reviews Drug Discovery · doi:10.1038/nrd2591 · Cited by 3,651

Extracellular vesicles: biology and emerging therapeutic opportunities

EL Andaloussi, S., Mäger, I., Breakefield, X. O., & Wood, M. J. A. (2013) · Nature Reviews Drug Discovery · doi:10.1038/nrd3978 · Cited by 3,571

Epstein-Barr virus infection upregulates extracellular OLFM4 to activate YAP signaling during gastric cancer progression

Wen, F., Han, Y., Zhang, H., Zhao, Z., Wang, W., Chen, F., Qin, W., Ju, J., An, L., Yan, M., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-54850-6 · Cited by 30

Clinical Implications of Exosomes: Targeted Drug Delivery for Cancer Treatment

Massey, A. E., Malik, S., Sikander, M., Doxtater, K. D., Tripathi, M. K., Khan, S., Yallapu, M. M., Jaggi, M., Chauhan, S. C., & Hafeez, B. B. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22105278 · Cited by 27

Roles of the Exosomes Derived From Myeloid-Derived Suppressor Cells in Tumor Immunity and Cancer Progression

Chen, Z., Yuan, R., Hu, S., Yuan, W., & Sun, Z. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.817942 · Cited by 28

Extracellular Vesicles: A Novel Tool in Nanomedicine and Cancer Treatment

Stavrou, A., & Ortiz, A. (2022) · Cancers · doi:10.3390/cancers14184450 · Cited by 27

Fluorescence Spectroscopic Analysis of Lateral and Transbilayer Fluidity of Exosome Membranes

Yasuda, T., Watanabe, H., Hirosawa, K. M., Suzuki, K. G. N., Suga, K., & Hanashima, S. (2022) · Langmuir · doi:10.1021/acs.langmuir.2c02258 · Cited by 27

Unlocking Exosome-Based Theragnostic Signatures: Deciphering Secrets of Ovarian Cancer Metastasis

Mukherjee, S., Nag, S., Mukerjee, N., Maitra, S., Muthusamy, R., Fuloria, N. K., Fuloria, S., Adhikari, M. D., Anand, K., Thorat, N. D., et al. (2023) · ACS Omega · doi:10.1021/acsomega.3c02837 · Cited by 27

Acquired and intrinsic gemcitabine resistance in pancreatic cancer therapy: Environmental factors, molecular profile and drug/nanotherapeutic approaches

Ashrafizadeh, M., Luo, K., Zhang, W., Aref, A. R., & Zhang, X. (2023) · Environmental Research · doi:10.1016/j.envres.2023.117443 · Cited by 29

Strategies to target bioactive molecules to subcellular compartments. Focus on natural compounds

Biasutto, L., Mattarei, A., Spina, M. L., Azzolini, M., Parrasia, S., Szabó, I., & Zoratti, M. (2019) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2019.07.060 · Cited by 28

Highly efficient and label-free sensitive detection of tumor-derived exosome with an aptasensor-based microfluidic chip

Li, M., Yang, P., Wu, J., Ni, R., Yuan, H., Guo, Z., Zou, J., Gao, W., Cong, H., & Jin, Q. (2024) · Microchemical Journal · doi:10.1016/j.microc.2024.110875 · Cited by 26

Nanovesicle-mediated delivery of anticancer agents effectively induced cell death and regressed intrahepatic tumors in athymic mice

George, J., Yan, I. K., & Patel, T. C. (2018) · Laboratory Investigation · doi:10.1038/s41374-018-0053-4 · Cited by 26

Reprogramming Exosomes for Immunotherapy

Cheng, Q., Shi, X., & Zhang, Y. (2019) · Methods in molecular biology · doi:10.1007/978-1-0716-0203-4_12 · Cited by 27

Dual-Targeted Extracellular Vesicles to Facilitate Combined Therapies for Neuroendocrine Cancer Treatment

Si, Y., Guan, J.-S., Xu, Y., Chen, K., Kim, S., Zhou, L., Jaskula‐Sztul, R., & Liu, M. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12111079 · Cited by 26

Rapid isolation of extracellular vesicles from diverse biofluid matrices via capillary-channeled polymer fiber solid-phase extraction micropipette tips

Jackson, K. K., Powell, R. R., Bruce, T. F., & Marcus, R. K. (2021) · The Analyst · doi:10.1039/d1an00373a · Cited by 27

Exosome-Mediated Therapeutic Strategies for Management of Solid and Hematological Malignancies

Allegra, A., Petrarca, C., Gioacchino, M. D., Casciaro, M., Musolino, C., & Gangemi, S. (2022) · Cells · doi:10.3390/cells11071128 · Cited by 26

Current Update on the Role of Enhanced Permeability and Retention Effect in Cancer Nanomedicine

Jasim, A. A., Abdelghany, S., & Greish, K. F. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809717-5.00002-6 · Cited by 26

The Biological Function and Therapeutic Potential of Exosomes in Cancer: Exosomes as Efficient Nanocommunicators for Cancer Therapy

Choi, J. U., Park, I., Lee, Y.-K., & Hwang, S. R. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21197363 · Cited by 27

GFAP as Astrocyte-Derived Extracellular Vesicle Cargo in Acute Ischemic Stroke Patients—A Pilot Study

Forró, T., Manu, D. R., Băjenaru, O., & Bălașa, R. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25115726 · Cited by 25

Pathways for Modulating Exosome Lipids Identified By High-Density Lipoprotein-Like Nanoparticle Binding to Scavenger Receptor Type B-1

Angeloni, N. L., McMahon, K. M., Swaminathan, S., Plebanek, M. P., Osman, I., Volpert, O. V., & Thaxton, C. S. (2016) · Scientific Reports · doi:10.1038/srep22915 · Cited by 25

Exosomes in cancer

Bark, J. M., Kulasinghe, A., Amenábar, J. M., & Punyadeera, C. (2020) · Advances in clinical chemistry · doi:10.1016/bs.acc.2020.06.006 · Cited by 25

Characterization of Extracellular Vesicles by Size-Exclusion High-Performance Liquid Chromatography (HPLC)

Huang, T., & He, J. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-7253-1_15 · Cited by 25

Human placenta-derived amniotic epithelial cells as a new therapeutic hope for COVID-19-associated acute respiratory distress syndrome (ARDS) and systemic inflammation

Babajani, A., Moeinabadi‐Bidgoli, K., Niknejad, F., Rismanchi, H., Shafiee, S., Shariatzadeh, S., Jamshidi, E., Farjoo, M. H., & Niknejad, H. (2022) · Stem Cell Research & Therapy · doi:10.1186/s13287-022-02794-3 · Cited by 24

Mesenchymal Stem Cell-Derived Extracellular Vesicles and Their Therapeutic Use in Central Nervous System Demyelinating Disorders

Allegretta, C., D’Amico, E., Manuti, V., Avolio, C., & Conese, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073829 · Cited by 27

Decoding the role of extracellular vesicles in liver diseases

Deng, F., Magee, N. S., & Zhang, Y. (2017) · Liver Research · doi:10.1016/j.livres.2017.11.003 · Cited by 24

The Relationship between Exosomes and Cancer: Implications for Diagnostics and Therapeutics

Weston, W. W., Ganey, T. M., & Temple, H. T. (2019) · BioDrugs · doi:10.1007/s40259-019-00338-5 · Cited by 24

Exosome-mediated therapeutic delivery: A new horizon for human neurodegenerative disorders’ treatment (with a focus on siRNA delivery improvement)

Seyfizadeh, N., Seyfizadeh, N., Borzoueisileh, S., Elahimanesh, F., Hosseini, V., & Nouri, M. (2019) · Process Biochemistry · doi:10.1016/j.procbio.2019.06.025 · Cited by 24

In vivo CT imaging of gold nanoparticle-labeled exosomes in a myocardial infarction mouse model

Gong, L.-G., Weng, Y., Zhou, W., Zhang, K.-C., Li, W., Jiang, J., & Zhu, J. (2021) · Annals of Translational Medicine · doi:10.21037/atm-21-981 · Cited by 19

Exosomes in the Treatment of Pancreatic Cancer: A Moonshot to PDAC Treatment?

Papadakos, S. P., Dedes, N., Pergaris, A., Gazouli, M., & Theocharis, S. E. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073620 · Cited by 23

Impact of exosome therapy on pancreatic cancer and its progression

El‐Tanani, M., Nsairat, H., Matalka, I. I., Aljabali, A. A. A., Mishra, V. K., Mishra, Y., Naikoo, G. A., Chava, S. R., Charbe, N. B., & Tambuwala, M. M. (2023) · Medical Oncology · doi:10.1007/s12032-023-02101-x · Cited by 24

Extracellular vesicles: powerful candidates in nano-drug delivery systems

Liu, X., Cao, Y., Wang, S., Liu, J., & Hao, H. (2023) · Drug Delivery and Translational Research · doi:10.1007/s13346-023-01411-x · Cited by 24

Evidence of sequestration of triclabendazole and associated metabolites by extracellular vesicles of Fasciola hepatica

Davis, C. N., Winters, A. L., Milic, I., Devitt, A., Cookson, A., Brophy, P. M., & Morphew, R. M. (2020) · Scientific Reports · doi:10.1038/s41598-020-69970-4 · Cited by 23

New Optical Imaging Reporter-labeled Anaplastic Thyroid Cancer-Derived Extracellular Vesicles as a Platform for In Vivo Tumor Targeting in a Mouse Model

Gangadaran, P., Li, X. J., Kalimuthu, S., Oh, J. M., Hong, C. M., Rajendran, R. L., Lee, H., Zhu, L., Baek, S. H., Jeong, S. Y., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-31998-y · Cited by 22

Engineering of Exosomes: Steps Towards Green Production of Drug Delivery System

Sherif, A. Y., Harisa, G. I., Alanazi, F. K., & Youssof, A. M. E. (2019) · Current Drug Targets · doi:10.2174/1389450120666190715104100 · Cited by 22

Drug Delivery to the Bone Microenvironment Mediated by Exosomes: An Axiom or Enigma

Samal, S., Dash, P., & Dash, M. (2021) · International Journal of Nanomedicine · doi:10.2147/ijn.s307843 · Cited by 22

Isolation and Characterization of Crab Haemolymph Exosomes and Its Effects on Breast Cancer Cells (4T1).

Rezakhani, L., Alizadeh, M., Sharifi, E., Soleimannejad, M., & Alizadeh, A. (2021) · PubMed Central · doi:10.22074/cellj.2021.7595 · Cited by 22

Targeted EV to Deliver Chemotherapy to Treat Triple-Negative Breast Cancers

Si, Y., Chen, K., Ngo, H. G., Guan, J. S., Totoro, A., Zhou, Z. “., Kim, S., Kim, T. H., Zhou, L., & Liu, M. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14010146 · Cited by 22

Neutral ceramidase‐enriched exosomes prevent palmitic acid‐induced insulin resistance in H4 IIEC 3 hepatocytes

Zhu, Q., Zhu, R., & Jin, J. (2016) · FEBS Open Bio · doi:10.1002/2211-5463.12125 · Cited by 22

Exosomes: A Paradigm in Drug Development against Cancer and Infectious Diseases

Oves, M., Qari, H. A., Felemban, N. M., Khan, A. A. P., Rehan, M., Tabrez, S. S. M., Ahmed, F., Haque, A., Khan, M. S., Khan, J. M., et al. (2018) · Journal of Nanomaterials · doi:10.1155/2018/6895464 · Cited by 23

Highly Efficient Isolation and Sensitive Detection of Small Extracellular Vesicles Using a Paper-Based Device

Zhang, L., Yin, W., Tong, Y., Zhang, Y., Xu, Y., Liu, S., Dai, Z., & Zou, X. (2022) · Analytical Chemistry · doi:10.1021/acs.analchem.2c01378 · Cited by 21

A review on the use of extracellular vesicles for the delivery of drugs and biological therapeutics

Amina, S. J., Azam, T., Dagher, F., & Guo, B. (2024) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2024.2305115 · Cited by 21

Extracellular vesicles and ctDNA in lung cancer: biomarker sources and therapeutic applications

Huang, C.-L., Liu, S., Tong, X., & Fan, H. S. (2018) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-018-3586-8 · Cited by 22

Platelet microparticles: An effective delivery system for anti-viral drugs

Soleymani, S., Yari, F., Bolhassani, A., & Bakhshandeh, H. (2019) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2019.03.009 · Cited by 21

Intercellular Crosstalk Via Extracellular Vesicles in Tumor Milieu as Emerging Therapies for Cancer Progression

Pătraș, L., & Banciu, M. (2019) · Current Pharmaceutical Design · doi:10.2174/1381612825666190701143845 · Cited by 21

Exosome-Derived Noncoding RNAs as a Promising Treatment of Bone Regeneration

Yin, B., Ma, Q., Song, C., Zhao, L., Yu, F., Wang, C., Shi, Y., & Ye, L. (2021) · Stem Cells International · doi:10.1155/2021/6696894 · Cited by 20

Electrochemical microfluidic paper-based analytical devices for tumor marker detection

Yuan, Y., Liu, B., Wang, T., Li, N., Zhang, Z., & Zhang, H. (2022) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2022.116816 · Cited by 21

Analysis of Proteins and Peptides of Highly Purified CD9+ and CD63+ Horse Milk Exosomes Isolated by Affinity Chromatography

Sedykh, S. E., Purvinsh, L. V., Burkova, E. E., Dmitrenok, P. S., Ryabchikova, E. I., & Nevinsky, G. A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232416106 · Cited by 20

miR-124 delivered by BM-MSCs-derived exosomes targets MCT1 of tumor-infiltrating Treg cells and improves ovarian cancer immunotherapy

Gao, T. X., Lin, Y.-Q., Ye, H., & Lin, W.-M. (2023) · Neoplasma · doi:10.4149/neo_2023_230711n362 · Cited by 20

Exosomes as new generation vehicles for drug delivery systems

Dilsiz, N. (2024) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2024.105562 · Cited by 21

A review of RNA nanoparticles for drug/gene/protein delivery in advanced therapies: Current state and future prospects

Vosoughi, P., Naghib, S. M., Kangarshahi, B. M., & Mozafari, M. R. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.139532 · Cited by 23

Myocardial Regeneration via Progenitor Cell-Derived Exosomes

Maring, J. A., Beez, C. M., Falk, V., Seifert, M., & Stamm, C. (2017) · Stem Cells International · doi:10.1155/2017/7849851 · Cited by 21

Trends towards Biomimicry in Theranostics

Evangelopoulos, M., Parodi, A., Martinez, J. O., & Tasciotti, E. (2018) · Nanomaterials · doi:10.3390/nano8090637 · Cited by 20

Janus nanocarrier powered by bi-enzymatic cascade system for smart delivery

Jiménez‐Falcao, S., Joga, N., García‐Fernández, A., Llopis‐Lorente, A., Torres, D., de Luis, B., Sancenón, F., Martínez‐Ruiz, P., Martínez‐Máñez, R., & Villalonga, R. (2019) · Journal of Materials Chemistry B · doi:10.1039/c9tb00938h · Cited by 20

Clinical applications of extracellular vesicle long RNAs

Chen, S., Zhu, X., & Huang, S. (2020) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/10408363.2020.1751584 · Cited by 20

The physiological functions and therapeutic potential of exosomes during the development and treatment of polycystic ovary syndrome

Zhang, Z., Shi, C., & Wang, Z. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1279469 · Cited by 21

The Role of Exosomes in Cancer Progression and Therapy

Sergazy, S., Seydahmetova, R., Gulyayev, A., Shulgau, Z., & Aljofan, M. (2025) · Biology · doi:10.3390/biology14010027 · Cited by 23

Superfluorinated Extracellular Vesicles for In Vivo Imaging by 19F-MRI

Sancho‐Albero, M., Ayaz, N., Sebastián, V., Chirizzi, C., Encinas‐Giménez, M., Neri, G., Chaabane, L., Luján, L., Martín‐Duque, P., Metrangolo, P., et al. (2023) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c20566 · Cited by 20

A Single-Step Immunocapture Assay to Quantify HCC Exosomes Using the Highly Sensitive Fluorescence Nanoparticle-Tracking Analysis

Köksal, A. R., Ekmen, N., Aydın, Y., Núñez, K., Sandow, T. A., Delk, M., Moehlen, M., Thevenot, P., Cohen, A. J., & Dash, S. (2023) · Journal of Hepatocellular Carcinoma · doi:10.2147/jhc.s423043 · Cited by 20

Enhancement of cell uptake and antitumor activity of selenadiazole derivatives through interaction and delivery by serum albumin

Deng, S., Zeng, D., Luo, Y., Zhao, J., Li, X., Zhao, Z., & Chen, T. (2017) · RSC Advances · doi:10.1039/c6ra28801d · Cited by 19

Anticancer Phytocompounds

Aqil, F., Munagala, R., Agrawal, A. K., & Gupta, R. C. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-814619-4.00010-0 · Cited by 19

Exosome-Mediated Crosstalk Between Cancer Cells and Tumor Microenvironment

Saad, S. H., Kashanchi, A., Zadeh, M. A., Williams, A., & Batrakova, E. V. (2025) · Cells · doi:10.3390/cells14221750 · Cited by 25

Export of microRNAs: A Bridge between Breast Carcinoma and Their Neighboring Cells

Jahagirdar, D., Purohit, S., Jain, A. Y., & Sharma, N. K. (2016) · Frontiers in Oncology · doi:10.3389/fonc.2016.00147 · Cited by 18

Exosomal DEK removes chemoradiotherapy resistance by triggering quiescence exit of breast cancer stem cells

Yang, Y.-S., Jia, X.-Z., Lu, Q.-Y., Cai, S.-L., Huang, X.-T., Yang, S., Wood, C., Wang, Y., Zhou, J., Chen, Y., et al. (2022) · Oncogene · doi:10.1038/s41388-022-02278-x · Cited by 18

Engineered Exosomes as a Photosensitizer Delivery Platform for Cancer Photodynamic Therapy

Dao, A., Kushwaha, R., Kumar, A., Huang, H., & Banerjee, S. (2022) · ChemMedChem · doi:10.1002/cmdc.202200119 · Cited by 18

Comparison of Different Isolation Methods for Plasma-Derived Extracellular Vesicles in Patients with Hyperlipidemia

Ke, Z., Wei, X., Zhi, Z., Zhang, S., Cui, L., Li, Y., Chen, X., Yao, J., & Zhang, H. (2022) · Life · doi:10.3390/life12111942 · Cited by 18

Urinary exosomes: Diagnostic impact with a bioinformatic approach

Perpétuo, L., Ferreira, R. M., Thongboonkerd, V., Guedes, S. D. M., Amado, F. M. L., & Vitorino, R. M. P. (2022) · Advances in clinical chemistry · doi:10.1016/bs.acc.2022.07.002 · Cited by 21

Potential for Therapeutic-Loaded Exosomes to Ameliorate the Pathogenic Effects of α-Synuclein in Parkinson’s Disease

Rademacher, D. J. (2023) · Biomedicines · doi:10.3390/biomedicines11041187 · Cited by 18

Vacuole-inducing compounds that disrupt endolysosomal trafficking stimulate production of exosomes by glioblastoma cells

Li, Z., Mbah, N. E., & Maltese, W. A. (2017) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-017-3130-x · Cited by 18

Cellular Vesicles: New Insights in Engineering Methods, Interaction with Cells and Potential for Brain Targeting

Marazioti, A., Παπαδιά, Κ., Kannavou, M., Σπέλλα, Μ., Basta, A., de Lastic, A.-L., Rodi, M., Mouzaki, Α., Samiotaki, M. K., Panayotou, G., et al. (2019) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.119.257097 · Cited by 19

Soluble fms‐like tyrosine kinase‐1‐enriched exosomes suppress the growth of small cell lung cancer by inhibiting endothelial cell migration

Hao, D., Li, Y., Zhao, G.-F., & Zhang, M. (2019) · Thoracic Cancer · doi:10.1111/1759-7714.13175 · Cited by 18

Brain Targeting and Toxicological Assessment of the Extracellular Vesicle-Packaged Antioxidant Catalase-SKL Following Intranasal Administration in Mice

Hayes, S. H., Liu, Q., Selvakumaran, S., Haney, M. J., Batrakova, E. V., Allman, B. L., Walton, P. A., Kiser, P. K., & Whitehead, S. N. (2021) · Neurotoxicity Research · doi:10.1007/s12640-021-00390-6 · Cited by 18

Biological Roles and Clinical Significance of Exosome-Derived Noncoding RNAs in Bladder Cancer

Tong, Y., Liu, X., Ding, X., Peng, E., Yang, X., Liu, H., Ye, T., Wang, X., He, Y., Xu, H., et al. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.704703 · Cited by 18

Chondrocyte-derived Exosomal miR-195 Inhibits Osteosarcoma Cell Proliferation and Anti-Apoptotic by Targeting KIF4A in vitro and in vivo

Lu, Y., Cao, G., Lan, H., Liao, H., Hu, Y., Feng, H., Liu, X., & Huang, P. (2021) · Translational Oncology · doi:10.1016/j.tranon.2021.101289 · Cited by 18

Extracellular Vesicle Proteome in Prostate Cancer: A Comparative Analysis of Mass Spectrometry Studies

Bernardino, R. M. M., Leao, R. R. N., Henrique, R., Pinheiro, L. C., Kumar, P., Suravajhala, P., Beck, H. C., Carvalho, A. S., & Matthiesen, R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222413605 · Cited by 19

Texosome-based drug delivery system for cancer therapy: from past to present.

Hosseini, H. M., Halabian, R., Amin, M., & Fooladi, A. A. I. (2015) · Europe PMC (PubMed Central) · doi:10.7497/j.issn.2095-3941.2015.0045 · Cited by 18

MSC Exosomes Containing Valproic Acid Promote Wound Healing by Modulating Inflammation and Angiogenesis

Mu, Y., Zhang, X., Zhang, L., Luo, R., Zhang, Y., & Wang, M. (2024) · Molecules · doi:10.3390/molecules29174281 · Cited by 17

Extracellular Vesicle-Mediated siRNA Delivery, Protein Delivery, and CFTR Complementation in Well-Differentiated Human Airway Epithelial Cells

Singh, B. K., Cooney, A. L., Krishnamurthy, S., & Sinn, P. L. (2020) · Genes · doi:10.3390/genes11040351 · Cited by 17

Exosome surface modification and functionalization: a narrative review of emerging technologies and their application potential in precision medicine

Chao, T., Zhao, J., Gao, R., Wang, H., Guo, J., Gao, Z., & Wang, Y. (2025) · Advanced technology in neuroscience . · doi:10.4103/atn.atn-d-24-00025 · Cited by 21

Inducible RNAi system and its application in novel therapeutics

Liao, Y., & Tang, L. (2015) · Critical Reviews in Biotechnology · doi:10.3109/07388551.2014.1003030 · Cited by 17

The Biology and Therapeutic Applications of Red Blood Cell Extracellular Vesicles

Zhang, D. X., Kiomourtzis, T., Lam, C. K., & Le, M. T. N. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.81758 · Cited by 19

The Potential of Nanomedicine to Alter Cancer Stem Cell Dynamics: The Impact of Extracellular Vesicles

Gener, P., González‐Callejo, P., Seras‐Franzoso, J., Andrade, F., Rafael, D. F. D. S., Abasolo, I., & Schwartz, S. (2020) · Nanomedicine · doi:10.2217/nnm-2020-0099 · Cited by 17

Characterization of RNA in Extracellular Vesicles

Fischer, S., & Deindl, E. (2021) · Applied Sciences · doi:10.3390/app11167520 · Cited by 18

Genetically reprogrammed exosomes for immunotherapy of acute myeloid leukemia

Zhang, L., Kao, G., Zhao, Y., Zhang, Z., Kim, H. S., Shi, X., Cheng, Q., Hou, T., Lenz, H., & Zhang, Y. (2025) · Molecular Therapy · doi:10.1016/j.ymthe.2025.01.025 · Cited by 17

Advances in Research on Exosomal miRNAs in Central Nervous System Diseases

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Interleukin-4 Receptor Targeting Peptide Decorated Extracellular Vesicles as a Platform for In Vivo Drug Delivery to Thyroid Cancer

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