The DOI matches its Crossref record; 264 of the 264 references it cites were found in a registry or an index.
Metabolic reprogramming for cancer cells and their microenvironment: Beyond the Warburg Effect
Abstract
While metabolic reprogramming of cancer cells has long been considered from the standpoint of how and why cancer cells preferentially utilize glucose via aerobic glycolysis, the so-called Warburg Effect, the progress in the following areas during the past several years has substantially advanced our understanding of the rewired metabolic network in cancer cells that is intertwined with oncogenic signaling. First, in addition to the major nutrient substrates glucose and glutamine, cancer cells have been discovered to utilize a variety of unconventional nutrient sources for survival. Second, the deregulated biomass synthesis is intertwined with cell cycle progression to coordinate the accelerated progression of cancer cells. Third, the reciprocal regulation of cancer cell's metabolic alterations and the microenvironment, involving extensive host immune cells and microbiota, have come into view as critical mechanisms to regulate cancer progression. These and other advances are shaping the current and future paradigm of cancer metabolism.
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1 retracted
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From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
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Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors
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Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients
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Reyes-Farias, M., & Carrasco-Pozo, C. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20133177 · Cited by 689
Serine, glycine and one‑carbon metabolism in cancer (Review)
Pan, S., Fan, M., Liu, Z., Li, X., & Wang, H. (2020) · International Journal of Oncology · doi:10.3892/ijo.2020.5158 · Cited by 227
Cellular landscaping of cisplatin resistance in cervical cancer
Bhattacharjee, R., Dey, T., Kumar, L., Kar, S., Sarkar, R., Ghorai, M., Malik, S., Jha, N. K., Vellingiri, B., Kesari, K. K., et al. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113345 · Cited by 93
Zhang, Y., Liu, Z., Wang, X., Jian, H., Xiao, H., & Wen, T. (2022) · Cancer Gene Therapy · doi:10.1038/s41417-022-00470-5 · Cited by 47
Prognostic value of glycolysis markers in pancreatic cancer: A systematic review and meta-analysis
Wang, C., Xu, R., Song, J., Chen, Y., Yin, X., Ruze, R., & Xu, Q. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.1004850 · Cited by 6
Metadata
- Authors
- Sun, L., Suo, C., Li, S.-T., Zhang, H., & Gao, P.
- Venue
- Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
- Publisher
- Elsevier BV
- Published
- 2018-08
- Volume
- 1870
- Issue
- 1
- Pages
- 51-66
- ISSN
- 0304-419X (ISSN-L)
- OpenAlex
- W2810358408
- Cited by
- 363
- References
- 264
- FWCI
- 7.45
- Type
- journal article
- Language
- en
- Open access
- closed
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- Sun, L., Suo, C., Li, S.-T., Zhang, H., & Gao, P. (2018). Metabolic reprogramming for cancer cells and their microenvironment: Beyond the Warburg Effect. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. https://doi.org/10.1016/j.bbcan.2018.06.005
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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