Molecular biology of 5-HT receptors

High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor

Cherezov, V., Rosenbaum, D. M., Hanson, M. A., Rasmussen, S. G. F., Thian, F. S., Kobilka, T. S., Choi, H., Kühn, P., Weis, W. I., Kobilka, B. K., et al. (2007) · Science · doi:10.1126/science.1150577 · Cited by 3,280

A review of central 5-HT receptors and their function

Barnes, N. M., & Sharp, T. (1999) · Neuropharmacology · doi:10.1016/s0028-3908(99)00010-6 · Cited by 3,211

International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin).

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Molecular, pharmacological and functional diversity of 5-HT receptors

Hoyer, D., Hannon, J. P., & Martin, G. R. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00746-8 · Cited by 1,898

Multiple Serotonin Receptors: Differential Binding of [3H]5-Hydroxytryptamine, [3H]Lysergic Acid Diethylamide and [3H]Spiroperidol

Peroutka, S. J., & Snyder, S. H. (1979) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)13812-1 · Cited by 1,363

GPCR Engineering Yields High-Resolution Structural Insights into β 2 -Adrenergic Receptor Function

Rosenbaum, D. M., Cherezov, V., Hanson, M. A., Rasmussen, S. G. F., Thian, F. S., Kobilka, T. S., Choi, H., Yao, X.-J., Weis, W. I., Stevens, R. C., et al. (2007) · Science · doi:10.1126/science.1150609 · Cited by 1,335

Eating disorder and epilepsy in mice lacking 5-HT2C serotonin receptors

Tecott, L. H., Sun, L. M., Akana, S. F., Strack, A. M., Lowenstein, D. H., Dallman, M. F., & Julius, D. J. (1995) · Nature · doi:10.1038/374542a0 · Cited by 1,275

Proposals for the classification and nomenclature of functional receptors for 5-hydroxytryptamine

Bradley, P. B., Engel, G., Feniuk, W., Fozard, J. R., Humphrey, P. P. A., Middlemiss, D. N., Mylecharane, E. J., Richardson, B. P., & Saxena, P. R. (1986) · Neuropharmacology · doi:10.1016/0028-3908(86)90207-8 · Cited by 1,259

Regulation of serotonin-2C receptor G-protein coupling by RNA editing

Burns, C. M., Chu, H., Rueter, S. M., Hutchinson, L. K., Canton, H., Sanders-Bush, E., & Emeson, R. B. (1997) · Nature · doi:10.1038/387303a0 · Cited by 1,010

Primary Structure And Functional Expression of the 5HT 3 Receptor, A Serotonin-gated Ion Channel

Maricq, A. V., Peterson, A. S., Brake, A. J., Myers, R., & Julius, D. J. (1991) · Science · doi:10.1126/science.1718042 · Cited by 978

CBD and the 5-HT1A receptor: A medicinal and pharmacological review

Alexander, C., Jeon, J., Nickerson, K., Hassler, S. N., & Vasefi, M. (2025) · Biochemical Pharmacology · doi:10.1016/j.bcp.2025.116742 · Cited by 28

Serotonin, Kynurenine, and Indole Pathways of Tryptophan Metabolism in Humans in Health and Disease

Holeček, M. (2026) · Nutrients · doi:10.3390/nu18030507 · Cited by 30

5-hydroxytryptamine subtype 6 receptor modulators: a patent survey

Ivachtchenko, A. V., Ivanenkov, Y. A., & Tkachenko, S. E. (2010) · Expert Opinion on Therapeutic Patents · doi:10.1517/13543776.2010.494661 · Cited by 28

Autoradiographic study of serotonin transporter during memory formation

Tellez, R., Rocha, L., Castillo, C., & Meneses, A. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.03.015 · Cited by 28

Inhibition of serotonin receptor type 1 in acute myeloid leukemia impairs leukemia stem cell functionality: a promising novel therapeutic target

Etxabe, A., Lara-Castillo, M. C., Cornet-Masana, J. M., Banús‐Mulet, A., Nomdedéu, M., Torrente, M. Á., Pratcorona, M., Díaz‐Beyá, M., Esteve, J., & Risueño, R. M. (2017) · Leukemia · doi:10.1038/leu.2017.52 · Cited by 28

Antidepressive-like effect of imperatorin from Angelica dahurica in prenatally stressed offspring rats through 5-hydroxytryptamine system

Cao, Y., Liu, J., Wang, Q., Liu, M., Cheng, Y., Zhang, X., Lin, T., & Zhu, Z. (2017) · Neuroreport · doi:10.1097/wnr.0000000000000778 · Cited by 28

Contribution of Corticotropin-Releasing Factor Receptor 1 (CRF1) to Serotonin Receptor 5-HT2CR Function in Amygdala Neurons in a Neuropathic Pain Model

Ji, G., & Neugebauer, V. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20184380 · Cited by 28

Aberrant serotonergic signaling contributes to the hyperexcitability of CA1 pyramidal neurons in a mouse model of Alzheimer’s disease

Wang, J., Mei, Y., Zhang, X., Wei, X., Zhang, Y., Wang, D., Huang, J., Zhu, K., Peng, G., & Sun, B. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112152 · Cited by 30

Zinc Is Involved in Depression by Modulating G Protein-Coupled Receptor Heterodimerization

Tena-Campos, M., Ramon, E., Lupala, C., Pérez, J., Koch, K., & Garriga, P. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9153-y · Cited by 26

The relevance of preclinical research models for the development of antimigraine drugs: Focus on 5-HT1B/1D and CGRP receptors

Gupta, S. K., & Villalón, C. M. (2010) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2010.06.005 · Cited by 28

Essential Roles of Dopamine and Serotonin in Tooth Repair: Functional Interplay Between Odontogenic Stem Cells and Platelets

Baudry, A., Alleaume‐Butaux, A., Dimitrova-Nakov, S., Goldberg, M., Schneider, B., Launay, J., & Kellermann, O. (2015) · Stem Cells · doi:10.1002/stem.2037 · Cited by 28

The selective 5-HT2A receptor agonist 25CN-NBOH: Structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [3H]25CN-NBOH

Jensen, A. A., Halberstadt, A. L., Märcher-Rørsted, E., Odland, A. U., Chatha, M., Speth, N., Liebscher, G., Hansen, M., Bräuner-Osborne, H., Palner, M., et al. (2020) · Biochemical Pharmacology · doi:10.1016/j.bcp.2020.113979 · Cited by 28

Quantitative changes in intracellular calcium and extracellular-regulated kinase activation measured in parallel in CHO cells stably expressing serotonin (5-HT) 5-HT2A or 5-HT2Creceptors

Seitz, P. K., Bremer, N. M., McGinnis, A. G., Cunningham, K. A., & Watson, C. S. (2012) · BMC Neuroscience · doi:10.1186/1471-2202-13-25 · Cited by 27

Role of serotonin in vertebrate embryo development

Romero-Reyes, J., Molina‐Hernández, A., Díaz, N. F., & Camacho‐Arroyo, I. (2020) · Reproductive Biology · doi:10.1016/j.repbio.2020.100475 · Cited by 27

Herbal medicines for insomnia through regulating 5-hydroxytryptamine receptors: a systematic review

Haoran, W. A. N. G., Gu, Y., Khalid, R., Chen, X., & Han, T. (2023) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(23)60405-4 · Cited by 27

Serotonin receptor gene (5-HT1A) modulates alexithymic characteristics and attachment orientation

Gong, P., Liu, J., She, L., & Zhou, X. (2014) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2014.09.001 · Cited by 27

DPCPX, a selective adenosine A1 receptor antagonist, enhances the antidepressant-like effects of imipramine, escitalopram, and reboxetine in mice behavioral tests

Szopa, A., Poleszak, E., Bogatko, K., Wyska, E., Wośko, S., Doboszewska, U., Świąder, K., Właź, A., Dudka, J., Wróbel, A., et al. (2018) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-018-1551-z · Cited by 27

Conventional and Novel Pharmacological Approaches to Treat Dopamine-Related Disorders: Focus on Parkinson’s Disease and Schizophrenia

de la Mora, M. P., Hernández-Mondragón, J. C., Crespo‐Ramírez, M., Rejón-Orantes, J. D. C., Borroto‐Escuela, D. O., & Fuxé, K. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.07.026 · Cited by 28

5-HT3 receptor influences the washing phenotype and visual organization in obsessive-compulsive disorder supporting 5-HT3 receptor antagonists as novel treatment option

Lennertz, L., Wagner, M., Grabe, H. J., Franke, P. E., Guttenthaler, V., Rampacher, F., Schulze‐Rauschenbach, S., Vogeley, A., Benninghoff, J., Ruhrmann, S., et al. (2013) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2013.07.003 · Cited by 26

L-type calcium channels contribute to 5-HT3-receptor-evoked CaMKIIα and ERK activation and induction of emesis in the least shrew (Cryptotis parva)

Hutchinson, T. E., Zhong, W., Chebolu, S., Wilson, S. M., & Darmani, N. A. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2015.02.042 · Cited by 26

Neurotransmitter-based strategies for the treatment of cognitive dysfunction in Down syndrome

Das, D., Phillips, C., Hsieh, W., Sumanth, K., Dang, V., & Salehi, A. (2014) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2014.05.004 · Cited by 27

Serotonin

Hensler, J. G. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-374947-5.00015-8 · Cited by 31

Serotonin and Depression: Scrutiny of New Targets for Future Anti- Depressant Drug Development

Pannu, A. S., & Goyal, R. K. (2023) · Current Drug Targets · doi:10.2174/1389450124666230425233727 · Cited by 25

Phylogenetic Analysis and Selection Pressures of 5-HT Receptors in Human and Non-human Primates: Receptor of an Ancient Neurotransmitter

Anbazhagan, P., Purushottam, M., Kumar, H. B. K., Mukherjee, O., Jain, S., & Sowdhamini, R. (2010) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2010.10508573 · Cited by 25

Association of Polymorphisms within the Serotonin Receptor Genes5-HTR1A,5-HTR1B,5-HTR2Aand5-HTR2Cand Migraine Susceptibility in a Turkish Population

Yavuz, Y., Coşkun, S., Cengiz, B., Ozdemir, H. H., Uzar, E., Çim, A., Camkurt, M. A., & Aluçlu, M. U. (2016) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2016.14.3.250 · Cited by 25

Identification and functional characterisation of 5-HT4 receptor in sea cucumber Apostichopus japonicus (Selenka)

Wang, T., Yang, Z., Zhou, N., Sun, L., Lv, Z., & Wu, C. (2017) · Scientific Reports · doi:10.1038/srep40247 · Cited by 25

Insight into Ginkgo biloba L. Extract on the Improved Spatial Learning and Memory by Chemogenomics Knowledgebase, Molecular Docking, Molecular Dynamics Simulation, and Bioassay Validations

Chen, Y., Feng, Z., Shen, M., Lin, W., Wang, Y., Wang, S., Li, C., Wang, S., Chen, M., Shan, W., et al. (2020) · ACS Omega · doi:10.1021/acsomega.9b03960 · Cited by 27

5-HT2A receptor-mediated excitation on cerebellar fastigial nucleus neurons and promotion of motor behaviors in rats

Zhang, C.-Z., Zhuang, Q., He, Y.-C., Li, G.-Y., Zhu, J.-N., & Wang, J.-J. (2013) · Pflügers Archiv: European Journal of Physiology · doi:10.1007/s00424-013-1378-x · Cited by 22

Presynaptic Serotonergic Gating of the Subthalamonigral Glutamatergic Projection

Ding, S., Li, L., & Zhou, F.-M. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.4111-12.2013 · Cited by 23

Modulation of the subthalamic nucleus activity by serotonergic agents and fluoxetine administration

Aristieta, A., Morera‐Herreras, T., Ruíz-Ortega, J. Á., Miguélez, C., Vidaurrazaga, I., Arrúe, A., Zumárraga, M., & Ugedo, L. (2013) · Psychopharmacology · doi:10.1007/s00213-013-3333-0 · Cited by 24

Risk of prenatal depression and stress treatment: alteration on serotonin system of offspring through exposure to Fluoxetine

Pei, S., Liu, L., Zhong, Z., Wang, H., Lin, S., & Shang, J. (2016) · Scientific Reports · doi:10.1038/srep33822 · Cited by 27

Genetic Polymorphisms of 5-HT Receptors and Antipsychotic-Induced Metabolic Dysfunction in Patients with Schizophrenia

Paderina, D. Z., Boiko, A. S., Pozhidaev, I. V., Бочарова, А. В., Mednova, I. A., Fedorenko, O. Y., Kornetova, E. G., LOONEN, A. J. M., Semke, A. V., Bokhan, N. A., et al. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11030181 · Cited by 24

Activation of serotonin 5-HT1B receptor in the dorsal raphe nucleus affects REM sleep in the rat

Monti, J. M., Jantos, H., & Lagos, P. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.08.037 · Cited by 24

The therapeutic potential of G-protein coupled receptors in Huntington's disease

Dowie, M. J., Scotter, E. L., Molinari, E., & Glass, M. (2010) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2010.07.008 · Cited by 26

Enhanced Renewal of Erythroid Progenitors in Myelodysplastic Anemia by Peripheral Serotonin

Sibon, D., Coman, T., Rossignol, J., Lamarque, M., Kosmider, O., Bayard, E., Fouquet, G., Rignault‐Bricard, R., Topçu, S., Bonneau, P., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.02.071 · Cited by 23

Serotonin system is partially involved in immunomodulation of Nile tilapia (Oreochromis niloticus) immune cells

Li, Q., Jiang, B., Zhang, Z., Huang, Y., Xu, Z., Chen, X., Hou, X., Cai, J., Huang, Y. S., & Jian, J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.944388 · Cited by 23

Sonophoresis-assisted transdermal delivery of antimigraine-loaded nanolipomers: Radio-tracking, histopathological assessment and in-vivo biodistribution study

Tawfik, M. A., Taweel, M. M. E., Farag, M. M., Shamsel‐Din, H. A., & Ibrahim, A. B. (2023) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2023.123338 · Cited by 23

Identification of Glycyrrhiza as the rikkunshito constituent with the highest antagonistic potential on heterologously expressed 5-HT3A receptors due to the action of flavonoids

Herbrechter, R., Ziemba, P. M., Hoffmann, K. M., Hatt, H. H., Werner, M., & Gisselmann, G. (2015) · Frontiers in Pharmacology · doi:10.3389/fphar.2015.00130 · Cited by 23

5-HT4 Receptor Stimulation Leads to Soluble AβPPα Production Through MMP-9 Upregulation

Hashimoto, G., Sakurai, M., Teich, A. F., Saeed, F., Aziz, F., & Arancio, O. (2012) · Journal of Alzheimer s Disease · doi:10.3233/jad-2012-111235 · Cited by 25

Serotonin induces peripheral mechanical antihyperalgesic effects in mice

Aguiar, D. D., Petrocchi, J. A., Navarro, L. C., Souza, T. C., Castor, M. G. M. E., Perez, A. C., Duarte, I. D. G., & Romero, T. R. L. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2015.10.012 · Cited by 23

Computational Methods for the Identification of Molecular Targets of Toxic Food Additives. Butylated Hydroxytoluene as a Case Study

Tortosa, V., Pietropaolo, V., Brandi, V., Macari, G., Pasquadibisceglie, A., & Polticelli, F. (2020) · Molecules · doi:10.3390/molecules25092229 · Cited by 23

Effect of 5-HT2C receptor agonist and antagonist on chronic unpredictable stress (CUS) - Mediated anxiety and depression in adolescent Wistar albino rat: Implicating serotonin and mitochondrial ETC-I function in serotonergic neurotransmission

Wankhar, W., Syiem, D., Pakyntein, C. L., Thabah, D., & Sunn, S. E. (2020) · Behavioural Brain Research · doi:10.1016/j.bbr.2020.112780 · Cited by 22

New Approaches for the Treatment of Sleep Disorders

DeMartinis, N. A., Kamath, J., & Winokur, A. (2009) · Advances in pharmacology · doi:10.1016/s1054-3589(08)57005-0 · Cited by 23

Serotonin regulates dynamics of cerebellar granule cell activity by modulating tonic inhibition

Fleming, E., & Hull, C. (2018) · Journal of Neurophysiology · doi:10.1152/jn.00492.2018 · Cited by 23

Molecular biology of serotonergic systems in avian brains

Fujita, T., Aoki, N., Mori, C., Homma, K. J., & Yamaguchi, S. (2023) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2023.1226645 · Cited by 22

A new perspective on hippocampal synaptic plasticity and post‐stroke depression

Sun, N., Cui, W., Min, X., Zhang, G., Liu, J., & Wu, H. (2023) · European Journal of Neuroscience · doi:10.1111/ejn.16093 · Cited by 24

Eating disorders: Do PET and SPECT have a role? A systematic review of the literature.

Gianni, A. D., Donatis, D. D., Valente, S., Ronchi, D. D., & Atti, A. R. (2020) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2020.111065 · Cited by 22

Functional MRI to assess alterations of functional networks in response to pharmacological or genetic manipulations of the serotonergic system in mice

Razoux, F., Baltes, C., Mueggler, T., Seuwen, A., Russig, H., Mansuy, I. M., & Rudin, M. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.02.031 · Cited by 23

5-HT1A receptors transactivate the platelet-derived growth factor receptor type beta in neuronal cells

Kruk, J. S., Vasefi, M., Liu, H., Heikkila, J. J., & Beazely, M. A. (2012) · Cellular Signalling · doi:10.1016/j.cellsig.2012.09.021 · Cited by 22

The effect of sertraline and 8-OH-DPAT on the PTZ_induced seizure threshold: Role of the nitrergic system

Heydari, A., & Davoudi, S. (2016) · Seizure · doi:10.1016/j.seizure.2016.12.005 · Cited by 22

Outlining migrainous through dihydroergotamine–serotonin receptor interactions using quantum biochemistry

Neto, J. X., Soares-Rachetti, V. D. P., Albuquerque, E. L., Manzoni, V., & Fulco, U. L. (2018) · New Journal of Chemistry · doi:10.1039/c7nj03645k · Cited by 22

Serotonin and substance P: Synergy or competition in the control of breathing

Szereda‐Przestaszewska, M., & Kaczyńska, K. (2020) · Autonomic Neuroscience · doi:10.1016/j.autneu.2020.102658 · Cited by 22

Control of Breathing in Ectothermic Vertebrates

Milsom, W. K., Gilmour, K. M., Perry, S. F., Gargaglioni, L. H., Hedrick, M. S., Kinkead, R., & Wang, T. (2022) · Comprehensive physiology · doi:10.1002/cphy.c210041 · Cited by 30

Three-Dimensional Biologically Relevant Spectrum (BRS-3D): Shape Similarity Profile Based on PDB Ligands as Molecular Descriptors

Hu, B., Kuang, Z., Feng, S., Wang, D., He, S.-B., & De, K. (2016) · Molecules · doi:10.3390/molecules21111554 · Cited by 21

Effect of SSRI exposure on the proliferation rate and glucose uptake in breast and ovary cancer cell lines

Stapel, B., Melzer, C., von der Ohe, J., Hillemanns, P., Bleich, S., Kahl, K. G., & Hass, R. (2021) · Scientific Reports · doi:10.1038/s41598-020-80850-9 · Cited by 21

Cardamonin Modulates Neuropathic Pain through the Possible Involvement of Serotonergic 5-HT1A Receptor Pathway in CCI-Induced Neuropathic Pain Mice Model

Kaswan, N. K., Izham, N. A. B. M., Mohamad, T. T. T., Sulaiman, M., & Perimal, E. (2021) · Molecules · doi:10.3390/molecules26123677 · Cited by 16

Development and challenges in the discovery of 5-HT1A and 5-HT7 receptor ligands

Singh, D., Singh, P., Srivastava, P., Kakkar, D., Pathak, M., & Tiwari, A. K. (2022) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2022.106254 · Cited by 21

Dorsal raphe nucleus projecting retinal ganglion cells: Why Y cells?

Pickard, G. E., So, K., & Pu, M. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.08.004 · Cited by 21

Robust presynaptic serotonin 5-HT1Breceptor inhibition of the striatonigral output and its sensitization by chronic fluoxetine treatment

Ding, S., Li, L., & Zhou, F.-M. (2015) · Journal of Neurophysiology · doi:10.1152/jn.00831.2014 · Cited by 20

Dendrimeric tetravalent ligands for the serotonin-gated ion channel

Paolino, M., Mennuni, L., Giuliani, G., Anzini, M., Lanza, M., Caselli, G., Galimberti, C., Menziani, M. C., Donati, A., & Cappelli, A. (2014) · Chemical Communications · doi:10.1039/c4cc02502d · Cited by 21

Inhibition of serotonin reuptake in the prepubertal rat ovary by fluoxetine and effects on ovarian functions

Romero-Reyes, J., Cárdenas, M., Damián‐Matsumura, P., Domı́nguez, R., & Ayala, M. E. (2015) · Reproductive Toxicology · doi:10.1016/j.reprotox.2015.12.006 · Cited by 21

Dose related effects of buspirone on pain, learning / memory and food intake

Haleem, D. J., Nawaz, S., & Salman, T. (2018) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2018.09.017 · Cited by 21

Effects of diphenyl diselenide on depressive-like behavior in ovariectomized mice submitted to subchronic stress: involvement of the serotonergic system

da Rocha, J. T., Gai, B. M., Pinton, S., Sampaio, T. B., Nogueira, C. W., & Zeni, G. R. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2675-3 · Cited by 21

Modulation of Vasoactivity and Platelet Aggregation by Selective 5-HT Receptor Antagonism in Humans

Moerland, M., Kemme, M. J. B., Dijkmans, A. C., Bergougnan, L., & Burggraaf, J. (2011) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0b013e31822f6b8d · Cited by 21

Serotonergic modulation of basal ganglia circuits

Benarroch, E. E. (2009) · Neurology · doi:10.1212/wnl.0b013e3181b784e7 · Cited by 21

5-HT4 Receptor is Protective for MPTP-induced Parkinson’s Disease Mice Via Altering Gastrointestinal Motility or Gut Microbiota

Cui, C., Shi, Y. W., Hong, H., Zhou, Y., Qiao, C.-M., Zhao, L., Jia, X.-B., Zhao, W., & Shen, Y. (2023) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-023-10085-8 · Cited by 22

Class A and C GPCR Dimers in Neurodegenerative Diseases

Moreira, I. S., Caniceiro, A. B., Bueschbell, B., & Schiedel, A. C. (2022) · Current Neuropharmacology · doi:10.2174/1570159x20666220327221830 · Cited by 18

Psychedelics action and schizophrenia

Maćkowiak, M. (2023) · Pharmacological Reports · doi:10.1007/s43440-023-00546-5 · Cited by 22

A novel regulator of angiogenesis in endothelial cells: 5-hydroxytriptamine 4 receptor

Profirovic, J., Strekalova, E., Urao, N., Krbanjevic, A., Andreeva, A. V., Varadarajan, S., Fukai, T., Hen, R., Ushio‐Fukai, M., & Voyno-Yasenetskaya, T. (2012) · Angiogenesis · doi:10.1007/s10456-012-9296-7 · Cited by 22

Preventive effect of cyproheptadine hydrochloride in refractory patients with frequent migraine

Okuma, H., Iijima, K., Yasuda, T., Tokuoka, K., & Kitagawa, Y. (2013) · SpringerPlus · doi:10.1186/2193-1801-2-573 · Cited by 20

Serotonin and calcium homeostasis during the transition period

Weaver, S. R., Laporta, J., Moore, S. A. E., & Hernandez, L. L. (2016) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2015.11.004 · Cited by 20

Anti-dyskinetic efficacy of 5-HT3 receptor antagonist in the hemi-parkinsonian rat model

Aboulghasemi, N., Jahromy, M. H., & Ghasemi, A. (2018) · IBRO Reports · doi:10.1016/j.ibror.2018.12.001 · Cited by 20

Mirtazapine exerts an anxiolytic-like effect through activation of the median raphe nucleus-dorsal hippocampal 5-HT pathway in contextual fear conditioning in rats

An, Y., Chen, C., Inoue, T., Nakagawa, S., Kitaichi, Y., Wang, C., Izumi, T., & Kusumi, I. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2016.04.014 · Cited by 20

Serotonin in the orbitofrontal cortex enhances cognitive flexibilityPreprint

Hyun, J. H., Hannan, P., Iwamoto, H., Blakely, R., & Kwon, H. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.03.09.531880 · Cited by 18

Computational analysis of ligand recognition sites of homo- and heteropentameric 5-HT3 receptors

Barbosa, A. J. M., Rienzo, F. D., Ramos, M. J., & Menziani, M. C. (2010) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2010.07.039 · Cited by 19

The serotonin 2C receptor agonist WAY-163909 attenuates ketamine-induced hypothermia in mice

Murphy, T. J., & Murnane, K. S. (2018) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2018.11.003 · Cited by 19

Serotonin regulation of mitochondria in kidney diseases

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