Molecular biology of 5-HT receptors

High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor

Cherezov, V., Rosenbaum, D. M., Hanson, M. A., Rasmussen, S. G. F., Thian, F. S., Kobilka, T. S., Choi, H., Kühn, P., Weis, W. I., Kobilka, B. K., et al. (2007) · Science · doi:10.1126/science.1150577 · Cited by 3,280

A review of central 5-HT receptors and their function

Barnes, N. M., & Sharp, T. (1999) · Neuropharmacology · doi:10.1016/s0028-3908(99)00010-6 · Cited by 3,211

International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin).

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Molecular, pharmacological and functional diversity of 5-HT receptors

Hoyer, D., Hannon, J. P., & Martin, G. R. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00746-8 · Cited by 1,898

Multiple Serotonin Receptors: Differential Binding of [3H]5-Hydroxytryptamine, [3H]Lysergic Acid Diethylamide and [3H]Spiroperidol

Peroutka, S. J., & Snyder, S. H. (1979) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)13812-1 · Cited by 1,363

GPCR Engineering Yields High-Resolution Structural Insights into β 2 -Adrenergic Receptor Function

Rosenbaum, D. M., Cherezov, V., Hanson, M. A., Rasmussen, S. G. F., Thian, F. S., Kobilka, T. S., Choi, H., Yao, X.-J., Weis, W. I., Stevens, R. C., et al. (2007) · Science · doi:10.1126/science.1150609 · Cited by 1,335

Eating disorder and epilepsy in mice lacking 5-HT2C serotonin receptors

Tecott, L. H., Sun, L. M., Akana, S. F., Strack, A. M., Lowenstein, D. H., Dallman, M. F., & Julius, D. J. (1995) · Nature · doi:10.1038/374542a0 · Cited by 1,275

Proposals for the classification and nomenclature of functional receptors for 5-hydroxytryptamine

Bradley, P. B., Engel, G., Feniuk, W., Fozard, J. R., Humphrey, P. P. A., Middlemiss, D. N., Mylecharane, E. J., Richardson, B. P., & Saxena, P. R. (1986) · Neuropharmacology · doi:10.1016/0028-3908(86)90207-8 · Cited by 1,259

Regulation of serotonin-2C receptor G-protein coupling by RNA editing

Burns, C. M., Chu, H., Rueter, S. M., Hutchinson, L. K., Canton, H., Sanders-Bush, E., & Emeson, R. B. (1997) · Nature · doi:10.1038/387303a0 · Cited by 1,010

Primary Structure And Functional Expression of the 5HT 3 Receptor, A Serotonin-gated Ion Channel

Maricq, A. V., Peterson, A. S., Brake, A. J., Myers, R., & Julius, D. J. (1991) · Science · doi:10.1126/science.1718042 · Cited by 978

Adaptation in 5-HT2 receptors-CaMKII signaling in lateral habenula underlies increased nociceptive-sensitivity in ethanol-withdrawn rats

Zuo, W., Wu, L., Mei, Q., Zuo, Q., Zhou, Z., Fu, R., Li, W., Wu, W., Matthew, L., & Ye, J.-H. (2019) · Neuropharmacology · doi:10.1016/j.neuropharm.2019.107747 · Cited by 17

An Overview on the Hallucinogenic Peyote and Its Alkaloid Mescaline: The Importance of Context, Ceremony and Culture

Kleffens, M. D.-V., Zimmermann-Klemd, A. M., & Gründemann, C. (2023) · Molecules · doi:10.3390/molecules28247942 · Cited by 20

Acoustic trauma triggers upregulation of serotonin receptor genes

Smith, A. R., Kwon, J. H., Navarro, M. A., & Hurley, L. M. (2014) · Hearing Research · doi:10.1016/j.heares.2014.06.004 · Cited by 17

Impact of specific serotonin receptor modulation on restricted repetitive behaviors

Alvarez, B. D., Cavazos, C., Morales, C. A., Lopez, S. M., & Amodeo, D. A. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.1078983 · Cited by 17

Coriandrum sativum and Its Utility in Psychiatric Disorders

Santibáñez, A., Jiménez‐Ferrer, E., Angulo‐Bejarano, P. I., Sharma, A. K., & Herrera-Ruiz, M. L. (2023) · Molecules · doi:10.3390/molecules28145314 · Cited by 17

Lysergic Acid Diethylamide (LSD) for the Treatment of Anxiety Disorders: Preclinical and Clinical Evidence

Inserra, A., Piot, A., Gregorio, D. D., & Gobbi, G. (2023) · CNS Drugs · doi:10.1007/s40263-023-01008-5 · Cited by 19

Functional Evaluations of Genes Disrupted in Patients with Tourette’s Disorder

Sun, N., Tischfield, J. A., King, R. A., & Heiman, G. A. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00011 · Cited by 17

Novel optimized biopolymer-based nanoparticles for nose-to-brain delivery in the treatment of depressive diseases

Sorrentino, A., Cataldo, A., Curatolo, R., Tagliatesta, P., Mosca, L., & Stefano Bellucci, A. (2020) · RSC Advances · doi:10.1039/d0ra04212a · Cited by 17

The development of descending serotonergic modulation of the spinal nociceptive network: a life span perspective

de Kort, A. R., Joosten, E. A. J., Patijn, J., Tibboel, D., & van den Hoogen, N. J. (2021) · Pediatric Research · doi:10.1038/s41390-021-01638-9 · Cited by 17

Interplay between 5-HT2C and 5-HT1A receptors in the dorsal periaqueductal gray in the modulation of fear-induced antinociception in mice

Baptista‐de‐Souza, D., Pelarin, V., Canto‐de‐Souza, L., Nunes‐de‐Souza, R. L., & Canto‐de‐Souza, A. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.07.027 · Cited by 17

Molecular characterization, expression analysis, and functional properties of multiple 5-hydroxytryptamine receptors in Pacific abalone (Haliotis discus hannai)

Kim, K. S., Kim, M. A., & Sohn, Y. C. (2019) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2019.03.001 · Cited by 17

Sex and the serotonergic underpinnings of depression and migraine

Spies, M., Handschuh, P. A., Lanzenberger, R. R., & Kranz, G. S. (2020) · Handbook of clinical neurology · doi:10.1016/b978-0-444-64123-6.00009-6 · Cited by 17

Melanocortin 4 receptor stimulation prevents antidepressant-associated weight gain in mice caused by long-term fluoxetine exposure

Ortuño, M. J., Schneeberger, M., Ilanges, A., Marchildon, F., Pellegrino, K., Friedman, J. M., & Ducy, P. (2021) · Journal of Clinical Investigation · doi:10.1172/jci151976 · Cited by 18

Serotonin signaling regulates actomyosin contractility during morphogenesis in evolutionarily divergent lineages

Karki, S., Saadaoui, M., Dunsing, V., Kerridge, S., Silva, E. D., Philippe, J., Maurange, C., & Lecuit, T. (2023) · Nature Communications · doi:10.1038/s41467-023-41178-w · Cited by 16

Role of serotonin in the regulation of renal proximal tubular epithelial cells

Erikçi, A., Uçar, G., & Ciftci, S. Y. (2016) · Renal Failure · doi:10.1080/0886022x.2016.1194165 · Cited by 16

Cyanobacterial extract with serotonin receptor subtype 7 (5‐HT7R) affinity modulates depression and anxiety‐like behavior in mice

Lax, N. C., Parker, S. J., Hilton, E., Seliman, Y., Tidgewell, K. J., & Kolber, B. J. (2018) · Synapse · doi:10.1002/syn.22059 · Cited by 17

The dorsal arcopallium of chicks displays the expression of orthologs of mammalian fear related serotonin receptor subfamily genes

Fujita, T., Aoki, N., Mori, C., Fujita, E., Matsushima, T., Homma, K. J., & Yamaguchi, S. (2020) · Scientific Reports · doi:10.1038/s41598-020-78247-9 · Cited by 17

Bridging the gap between single receptor type activity and whole‐brain dynamics

Jancke, D., Herlitze, S., Kringelbach, M. L., & Deco, G. (2021) · FEBS Journal · doi:10.1111/febs.15855 · Cited by 17

Bivalent Ligands for the Serotonin 5-HT3 Receptor

Cappelli, A., Manini, M., Paolino, M., Gallelli, A., Anzini, M., Mennuni, L., Cadia, M. D., Rienzo, F. D., Menziani, M. C., & Vomero, S. (2011) · ACS Medicinal Chemistry Letters · doi:10.1021/ml2000388 · Cited by 16

Attenuation of serotonin-induced itch by sumatriptan: possible involvement of endogenous opioids

Haddadi, N., Foroutan, A., Shakiba, S., Afshari, K., Ostadhadi, S., Daneshpazhooh, M., & Dehpour, A. R. (2018) · Archives of Dermatological Research · doi:10.1007/s00403-018-1809-9 · Cited by 16

Activation of 5-HT1B receptors inhibits the vasodepressor sensory CGRPergic outflow in pithed rats

González‐Hernández, A., Muñoz‐Islas, E., Lozano‐Cuenca, J., Ramirez-Rosas, M. B., Sánchez‐López, A., Centurión, D., Juan, E. R., & Villalón, C. M. (2010) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2010.03.053 · Cited by 16

Molecular Cloning and Functional Characterization of Three 5-HT Receptor Genes (HTR1B, HTR1E, and HTR1F) in Chickens

Sun, C., Qiu, Y., Ren, Q., Zhang, X. L., Cao, B., Zou, Y., Li, J., Zhang, J., & Wang, Y. (2021) · Genes · doi:10.3390/genes12060891 · Cited by 15

Living, Heat-Killed Limosilactobacillus mucosae and Its Cell-Free Supernatant Differentially Regulate Colonic Serotonin Receptors and Immune Response in Experimental Colitis

Sun, Z., Huang, S., Yan, X., Zhang, X., Hao, Y., Jiang, L., & Dai, Z. (2024) · Nutrients · doi:10.3390/nu16040468 · Cited by 15

Targeting serotonin receptors with phytochemicals – an in-silico study

Elalouf, A., Yaniv‐Rosenfeld, A., & Maoz, H. (2024) · Scientific Reports · doi:10.1038/s41598-024-76329-6 · Cited by 16

Effect of central administration of the neurotrophic factors BDNF and GDNF on the functional activity and expression of 5-HT2A serotonin receptors in mice genetically predisposed to depressive-like behavior

Tsybko, A. S., Ilchibaeva, T. V., Kondaurova, E. M., Базовкина, Д. В., & Naumenko, V. S. (2014) · Molecular Biology · doi:10.1134/s0026893314060181 · Cited by 15

Evidence of fast serotonin transmission in frog slowly adapting type 1 responses

Press, D., Mutlu, S., & Güçlü, B. (2010) · Somatosensory & Motor Research · doi:10.3109/08990220.2010.516670 · Cited by 15

Supramolecular Glycodendrimer-Based Hybrid Drugs

Paolino, M., Komber, H., Mennuni, L., Caselli, G., Appelhans, D., Voit, B. I., & Cappelli, A. (2014) · Biomacromolecules · doi:10.1021/bm501057d · Cited by 15

Long-Term Effects of Chronic Buspirone during Adolescence Reduce the Adverse Influences of Neonatal Inflammatory Pain and Stress on Adaptive Behavior in Adult Male Rats

Буткевич, И. П., Михайленко, В. А., Vershinina, E. A., Aloisi, A. M., & Barr, G. A. (2017) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2017.00011 · Cited by 15

Bupropion Inhibits Serotonin Type 3AB Heteromeric Channels at Clinically Relevant Concentrations

Stuebler, A. G., & Jansen, M. (2019) · Molecular Pharmacology · doi:10.1124/mol.119.118349 · Cited by 15

5-Hydroxytryptamine Receptors and Tardive Dyskinesia in Schizophrenia

Pozhidaev, I. V., Paderina, D. Z., Fedorenko, O. Y., Kornetova, E. G., Semke, A. V., LOONEN, A. J. M., Bokhan, N. A., Wilffert, B., & Ivanova, S. А. (2020) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2020.00063 · Cited by 15

Molecular Biological Aspects of Depressive Disorders: A Modern View

Ushakova, V. M., Morozova, A. Y., Reznik, A. M., Kostyuk, G. P., & Chekhonin, V. P. (2020) · Molecular Biology · doi:10.1134/s0026893320050118 · Cited by 16

Serotonin receptor expression is dynamic in the liver during the transition period in Holstein dairy cows

Laporta, J., & Hernandez, L. L. (2014) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2014.11.005 · Cited by 17

Transcriptomic Analysis of the Mouse Mammary Gland Reveals New Insights for the Role of Serotonin in Lactation

Laporta, J., Peñagaricano, F., & Hernandez, L. L. (2015) · PLoS ONE · doi:10.1371/journal.pone.0140425 · Cited by 15

Activation of 5-HT2C (but not 5-HT1A) receptors in the amygdala enhances fear-induced antinociception: Blockade with local 5-HT2C antagonist or systemic fluoxetine

Tavares, L. R. R., Baptista‐de‐Souza, D., & Canto‐de‐Souza, A. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.03.008 · Cited by 15

Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder

Fuchs, C., Gennaccaro, L., Ren, E., Galvani, G., Trazzi, S., Medici, G., Loi, M., Conway, E., Devinsky, O., Rimondini, R., et al. (2019) · Neuropharmacology · doi:10.1016/j.neuropharm.2019.107746 · Cited by 17

Chronic Fluoxetine Impairs the Effects of 5-HT1A and 5-HT2C Receptors Activation in the PAG and Amygdala on Antinociception Induced by Aversive Situation in Mice

Baptista‐de‐Souza, D., Tavares, L. R. R., Furuya-da-Cunha, E. M., de Oliveira, P. E. C., Canto‐de‐Souza, L., Nunes‐de‐Souza, R. L., & Canto‐de‐Souza, A. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00260 · Cited by 15

Serotonin2B receptor blockade in the rat dorsal raphe nucleus suppresses cocaine-induced hyperlocomotion through an opposite control of mesocortical and mesoaccumbens dopamine pathways

Cathala, A., Devroye, C., Robert, É., Vallée, M., Revest, J., Artigas, F., & Spampinato, U. (2020) · Neuropharmacology · doi:10.1016/j.neuropharm.2020.108309 · Cited by 15

Sex differences in carcinoid syndrome: A gap to be closed

Ruggeri, R. M., Altieri, B., Grossrubatcher, E., Minotta, R., Tarsitano, M. G., Zamponi, V., MIsidori, A., Faggiano, A., Colao, A. M. L., & NIKE Group (2022) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-022-09719-8 · Cited by 15

Challenges for Developing PET Tracers: Isotopes, Chemistry, and Regulatory Aspects

Mach, R. H., & Schwarz, S. W. (2010) · PET Clinics · doi:10.1016/j.cpet.2010.02.002 · Cited by 15

Involvement of 5-HT2A, 5-HT2B and 5-HT2C receptors in mediating the ventrolateral orbital cortex-induced antiallodynia in a rat model of neuropathic pain

Xu, W.-J., Wang, Y., Zhao, Y., Jia, H., Tang, J., Huo, F.-Q., & Liu, H. (2019) · Neuroreport · doi:10.1097/wnr.0000000000001377 · Cited by 14

Is there an association of genetic polymorphisms of the catechol-O-methyltransferase gene (rs165656 and rs174675) and the 5-hydroxytryptamine receptor 2A gene (rs4941573 and rs6313) with sleep bruxism in individuals with obstructive sleep apnea?

Duarte, J., Pauletto, P., Polmann, H., Réus, J. C., de Souza, J. F., Gaio, D. C., Brancher, J. A., Vieira, A. R., Souza, C. M., Melo, G., et al. (2021) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2021.105315 · Cited by 14

5-HT4 receptor agonists treatment reduces tau pathology and behavioral deficit in the PS19 mouse model of tauopathy

Jiang, S., Sydney, E. J., Runyan, A. M., Serpe, R., Srikanth, M., Figueroa, H. Y., Yang, M., & Myeku, N. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1338502 · Cited by 14

Exploring the Asymmetric Body’s Influence on Interval Timing Behaviors of Drosophila melanogaster

Liu, Z., Sun, D., Song, Y., Zhang, T., & Kim, W. J. (2024) · Behavior Genetics · doi:10.1007/s10519-024-10193-y · Cited by 14

Serotonin Modulation of Dorsoventral Hippocampus in Physiology and Schizophrenia

Kandilakis, C. L., & Papatheodoropoulos, C. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26157253 · Cited by 14

Pharmacological studies of performance on the free-operant psychophysical procedure

Body, S., Cheung, T. H. C., Valencia-Torres, L., Olarte‐Sánchez, C. M., Fone, K. C. F., Bradshaw, C. M., & Szabadi, E. (2013) · Behavioural Processes · doi:10.1016/j.beproc.2013.02.004 · Cited by 14

The Appropriate Supplementary Level of Tryptophan in the Diet of Apis mellifera (Hymenoptera: Apidae) Worker Bees

Fengkui, Z., Xu, B., Ge, Z., & Hongfang, W. (2015) · Journal of Insect Science · doi:10.1093/jisesa/iev142 · Cited by 14

ROLE OF 5-HT2C RECEPTORS IN DYSKINESIA

LOONEN, A. J. M., & Ivanova, S. А. (2015) · University of Groningen research database (University of Groningen / Centre for Information Technology) · Cited by 14

Serotonin receptors nomenclature

Hoyer, D. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813323-1.00004-9 · Cited by 14

Therapeutic Targets for Neuroprotection and/or Enhancement of Functional Recovery Following Traumatic Brain Injury

Kelso, M. L., & Pauly, J. R. (2011) · Progress in molecular biology and translational science · doi:10.1016/b978-0-12-385506-0.00003-x · Cited by 14

The N-terminal region of the human 5-HT2C receptor has as a cleavable signal peptide

Jahnsen, J. A., & Uhlén, S. (2012) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2012.03.043 · Cited by 14

5-HT4-Receptors Modulate Induction of Long-Term Depression but Not Potentiation at Hippocampal Output Synapses in Acute Rat Brain Slices

Wawra, M., Fidzinski, P., Heinemann, U., Módy, I., & Behr, J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0088085 · Cited by 14

Microinjection of the 5-HT7 receptor antagonist SB-269970 into the rat brainstem and basal forebrain: Site-dependent effects on REM sleep

Monti, J. M., Leopoldo, M., Jantos, H., & Lagos, P. (2012) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2012.05.012 · Cited by 14

Chronic fluvoxamine treatment changes 5-HT2A/2C receptor-mediated behavior in olfactory bulbectomized mice

Oba, A., Nakagawasai, O., Onogi, H., Nemoto, W., Yaoita, F., Arai, Y., Tan–No, K., & Tadano, T. (2012) · Life Sciences · doi:10.1016/j.lfs.2012.11.005 · Cited by 14

Normal Distribution and Plasticity of Serotonin Receptors after Spinal Cord Injury and Their Impacts on Motor Outputs

Zhang, M. (2016) · InTech eBooks · doi:10.5772/63759 · Cited by 15

Serotonin Signalling in Flatworms: An Immunocytochemical Localisation of 5-HT7 Type of Serotonin Receptors in Opisthorchis felineus and Hymenolepis diminuta

Kreshchenko, N., Terenina, N., & Ermakov, A. (2021) · Biomolecules · doi:10.3390/biom11081212 · Cited by 10

5-Hydroxytryptamine G-Protein-Coupled Receptor Family Genes: Key Players in Cancer Prognosis, Immune Regulation, and Therapeutic Response

Liu, S., He, M., Sun, H., Wu, Y.-L. L. C., & Jin, W. (2024) · Genes · doi:10.3390/genes15121541 · Cited by 13

5-HT6 receptors: Contemporary views on their neurobiological and pharmacological relevance in neuropsychiatric disorders

Chagraoui, A., Thibaut, F., & Deurwaerdère, P. D. (2025) · Dialogues in Clinical Neuroscience · doi:10.1080/19585969.2025.2502028 · Cited by 16

Psychedelics, entactogens and psychoplastogens for depression and related disorders

Hoyer, D. (2025) · British Journal of Pharmacology · doi:10.1111/bph.70088 · Cited by 17

Effects of grazing different ergovaline concentrations on vasoactivity of bovine lateral saphenous vein1

Klotz, J. L., Aiken, G. E., Egert-McLean, A. M., Schrick, F. N., Chattopadhyay, N., & Harmon, D. L. (2018) · Journal of Animal Science · doi:10.1093/jas/sky163 · Cited by 13

Association and cis-mQTL analysis of variants in serotonergic genes associated with nicotine dependence in Chinese Han smokers

Han, H., Liu, Q., Yang, Z., Wang, M., Ma, Y., Cao, L., Cui, W., Yuan, W., Payne, T. J., Li, L., et al. (2018) · Translational Psychiatry · doi:10.1038/s41398-018-0290-8 · Cited by 13

Biophysics of Serotonin and the Serotonin1A Receptor

Sarkar, P., Kumar, G., Pal, S., & Chattopadhyay, A. (2019) · Serotonin · doi:10.1016/b978-0-12-800050-2.00001-2 · Cited by 14

S-adenosyl-l-methionine antidepressant-like effects involve activation of 5-HT1A receptors

Sales, A. J., Maciel, I. D. S., Crestani, C. C., Guimarães, F. S., & Joca, S. R. L. (2022) · Neurochemistry International · doi:10.1016/j.neuint.2022.105442 · Cited by 13

Gene identification in black cohosh (Actaea racemosa L.): expressed sequence tag profiling and genetic screening yields candidate genes for production of bioactive secondary metabolites

Spiering, M. J., Urban, L. A., Nuss, D. L., Gopalan, V., Stoltzfus, A., & Eisenstein, E. (2010) · Plant Cell Reports · doi:10.1007/s00299-010-0979-5 · Cited by 13

Postjunctional α2C-adrenoceptors mediate vasoconstriction in rat tail artery: influence of precontraction and temperature on vasoreactivity

Jantschak, F., Popp, A. M., Hofmann, R. A., Villalón, C. M., Centurión, D., & Pertz, H. H. (2010) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-010-0564-z · Cited by 13

Gene structure and expression of serotonin receptor HTR2Cin hypothalamic samples from infanticidal and control sows

Quilter, C. R., Bagga, M., Moinie, A., Junaid, F., & Sargent, C. A. (2012) · BMC Neuroscience · doi:10.1186/1471-2202-13-37 · Cited by 12

Convergent Synthesis of a 5HT7/5HT2 Dual Antagonist

Liang, J. T., Deng, X., & Mani, N. S. (2011) · Organic Process Research & Development · doi:10.1021/op2001194 · Cited by 13

Early antipsychotic treatment in juvenile rats elicits long-term alterations to the adult serotonin receptors

Santis, M. D., Huang, X., & Deng, C. (2018) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s158545 · Cited by 12

Serotonergic Drugs Inhibit Chikungunya Virus Infection at Different Stages of the Cell Entry Pathway

Bouma, E. M., van de Pol, D. P. I., Sanders, I. D., Rodenhuis‐Zybert, I. A., & Smit, J. M. (2020) · Journal of Virology · doi:10.1128/jvi.00274-20 · Cited by 13

Human Consciousness: The Role of Cerebral and Cerebellar Cortex, Vagal Afferents, and Beyond

Abdulgader, A. A. A. (2020) · IntechOpen eBooks · doi:10.5772/intechopen.95040 · Cited by 14

Role of peripheral 5-HT1D, 5-HT3 and 5-HT7 receptors in the mechanical allodynia induced by serotonin in mice

Junior, E. B. D. N., Romero, T. R. L., Dutra, M. M. G. B., Fiebich, B. L., Duarte, I. D. G., & Coelho, M. M. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.111210 · Cited by 13

Role of serotonergic system in thermoregulation in rats

Ishiwata, T. (2014) · The Journal of Physical Fitness and Sports Medicine · doi:10.7600/jpfsm.3.445 · Cited by 13

Study on the comorbid mechanisms of sarcopenia and late-life depression

Wu, J., Tang, J., Huang, D., Wang, Y., Zhou, E., Ru, Q., Xu, G., Chen, L., & Wu, Y. (2025) · Behavioural Brain Research · doi:10.1016/j.bbr.2025.115538 · Cited by 12

Targeting the serotonergic system in the treatment of neurodegenerative diseases—emerging therapies and unmet challenges

Brüge, A., Ponimaskin, E. G., & Labus, J. (2025) · Pharmacological Reviews · doi:10.1016/j.pharmr.2025.100071 · Cited by 13

Understanding Serotonin 5-HT2A Receptors-regulated cellular and molecular Mechanisms of Chronic Kidney Diseases

Kaur, G., & Krishan, P. (2020) · Renal Replacement Therapy · doi:10.1186/s41100-020-00268-x · Cited by 12

The Serotonergic System and Amyotrophic Lateral Sclerosis: A Review of Current Evidence

Lu, Y., Cheng, Y., Zhu, Y., Cui, L., & Li, X. (2023) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-023-01320-0 · Cited by 12

Acute Effects of Hallucinogens on Functional Connectivity: Psilocybin and Salvinorin-A

Bagdasarian, F. A., Hansen, H. D., Chen, J. E., Yoo, C., Placzek, M. S., Hooker, J. M., & Wey, H. (2024) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.4c00245 · Cited by 15

Pharmacological characterization of cannabidiol as a negative allosteric modulator of the 5-HT2A receptor

Billard, É., Torbey, A. G., Inserra, A., Grant, E., Bertazzo, A., Gregorio, D. D., Comai, S., Chatenet, D., Gobbi, G., & Hébert, T. E. (2025) · Cellular Signalling · doi:10.1016/j.cellsig.2025.111588 · Cited by 11

Functional characterization of 5-HT1A and 5-HT1B serotonin receptor signaling through G-protein-activated inwardly rectifying K+ channels in a fluorescence-based membrane potential assay

Gadgaard, C., & Jensen, A. A. (2020) · Biochemical Pharmacology · doi:10.1016/j.bcp.2020.113870 · Cited by 13

Modulatory Effect of Serotonergic System in Pentylenetetrazole-Induced Seizures and Associated Memory Deficit: Role of 5-HT1A and 5-HT2A/2C

Mishra, A., & Goel, R. K. (2020) · Journal of Epilepsy Research · doi:10.14581/jer.19012 · Cited by 12

Serotonin 2A (5-HT2A) receptor affects cell–matrix adhesion and the formation and maintenance of stress fibers in HEK293 cells

Jayakumar, J. A. K. J., Panicker, M. M., & Basu, B. (2020) · Scientific Reports · doi:10.1038/s41598-020-78595-6 · Cited by 12

Identification and characterization of a novel 5‐hydroxytryptamine receptor in the sea cucumber Apostichopus japonicus (Selenka)

Zhang, B., Yang, J., Han, T., Huang, D., Zhao, Z., Feng, J., Zhou, N., Xie, H., & Wang, T. (2021) · Journal of Experimental Zoology Part A Ecological and Integrative Physiology · doi:10.1002/jez.2450 · Cited by 12

Receptor-mediated biological effects of extracts obtained from three Asplenium species

Petkov, V., Ardasheva, R., Prissadova, N. A., Kristev, A. D., Stoyanov, P. S., & Argirova, M. (2021) · Zeitschrift für Naturforschung C · doi:10.1515/znc-2020-0223 · Cited by 12

Involvement of Serotonergic System in Oxaliplatin-Induced Neuropathic Pain

Lee, J. H., & Kim, W. (2021) · Biomedicines · doi:10.3390/biomedicines9080970 · Cited by 12

The roles of serotonin in cell adhesion and migration, and cytoskeletal remodeling

Jayakumar, J. A. K. J., & Panicker, M. M. (2021) · Cell Adhesion & Migration · doi:10.1080/19336918.2021.1963574 · Cited by 13

Midbrain raphe 5-HT 1A receptor activation alters the effects of ghrelin on appetite and performance in the elevated plus maze

Wauson, S. E. R., Sarkodie, K., Schuette, L. M., & Currie, P. J. (2015) · Journal of Psychopharmacology · doi:10.1177/0269881115581981 · Cited by 12

Homeostasis of glucose in the rainbow trout (Oncorhynchus mykissWalbaum): the role of serotonin

Tubio, R. I. C., Maceira, J. J. P., & Aldegunde, M. (2010) · Journal of Experimental Biology · doi:10.1242/jeb.035444 · Cited by 12

Novel insights into the potential involvement of 5-HT7 receptors in endocrine dysregulation in stress-related disorders

Terrón, J. A. (2014) · Reviews in the Neurosciences · doi:10.1515/revneuro-2014-0017 · Cited by 12

Serotonin in the Frontal Cortex: A Potential Therapeutic Target for Neurological Disorders

Lü, H., & Liu, Q.-S. (2017) · Biochemistry & Pharmacology Open Access · doi:10.4172/2167-0501.1000e184 · Cited by 10

Serotonin in stem cell based-dental repair and bone formation: A review

Baudry, A., Schneider, B., Launay, J., & Kellermann, O. (2018) · Biochimie · doi:10.1016/j.biochi.2018.07.030 · Cited by 12

5ʹUTR polymorphism in the serotonergic receptor HTR3A gene is differently associated with striatal Dopamine D2/D3 receptor availability in the right putamen in Fibromyalgia patients and healthy controls—Preliminary evidence

Ledermann, K., Hasler, G., Jenewein, J., Sprott, H., Schnyder, U., & Martin-Söelch, C. (2019) · Synapse · doi:10.1002/syn.22147 · Cited by 12

Serotonin Regulates β-Casein Expression via 5-HT7 Receptors in Human Mammary Epithelial MCF-12A Cells

Chiba, T., Kimura, S., Takahashi, K., Morimoto, Y., Maeda, T., Sanbe, A., Ueda, H., & Kudo, K. (2015) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b14-00723 · Cited by 12

Dual Role of Mosapride Citrate Hydrate on the Gastric Emptying Evaluated by the Breath Test in Conscious Rats

Uchida, M., Yamato, S., Shimizu, K., Amano, T., & Ariga, H. (2013) · Journal of Pharmacological Sciences · doi:10.1254/jphs.12237fp · Cited by 12

5-HT2A Receptor Activation Normalizes Exaggerated Fear Behavior in p-Chlorophenylalanine (PCPA)-Treated Rats

Hughes, C. R., Tran, L., & Keele, N. B. (2012) · Journal of Behavioral and Brain Science · doi:10.4236/jbbs.2012.24053 · Cited by 12

Blockade of 5-HT3 receptors at septal area increase blood pressure in unanaesthetized rats

Urzedo-Rodrigues, L. S., Ferreira, H. S., de Almeida, D. O., Medeiros, J. P., Batista, A. M., Silva, E. D. C. E., & Fregoneze, J. B. (2010) · Autonomic Neuroscience · doi:10.1016/j.autneu.2010.07.028 · Cited by 12

Central 5-HT3 receptor-induced hypothermia is associated with reduced metabolic rate and increased heat loss

Voronova, I. P., Naumenko, V. S., Khramova, G. M., Владимировна, К. Т., & Popova, N. K. (2011) · Neuroscience Letters · doi:10.1016/j.neulet.2011.09.024 · Cited by 12

The Substantia Nigra Pars Reticulata

Zhou, F. (2016) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-12-802206-1.00015-5 · Cited by 14

Effects of systemic 5-HT1B receptor compounds on ventral tegmental area intracranial self-stimulation thresholds in rats

Hayes, D. J., Graham, D. A., & Greenshaw, A. J. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2008.12.023 · Cited by 12

Deletion of the prion gene Prnp affects offensive aggression in mice

Büdefeld, T., Majer, A., Jerin, A., & Majdic, G. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.03.006 · Cited by 11

Reversal of electrophysiological and behavioral deficits mediated by 5-HT7 receptor upregulation following LP-211 treatment in an autistic-like rat model induced by prenatal valproic acid exposure

Rahdar, M., Davoudi, S., Dehghan, S., Javan, M., Hosseinmardi, N., Behzadi, G., & Janahmadi, M. (2024) · Neuropharmacology · doi:10.1016/j.neuropharm.2024.110057 · Cited by 11

Gain control of sensory input across polysynaptic circuitries in mouse visual cortex by a single G protein-coupled receptor type (5-HT2A)

Barzan, R., Bozkurt, B., Nejad, M. M., Süß, S. T., Surdin, T., Böke, H., Spoida, K., Azimi, Z., Grömmke, M., Eickelbeck, D., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-51861-1 · Cited by 12

Serotonin receptors nomenclature

Hoyer, D. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813323-1.00004-9 · Cited by 14

The 5-HT4 receptor: naughty, but nice

Clarke, D. E., Craig, D. A., & Fozard, J. R. (1989) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(89)90177-6 · Cited by 158

GR: Molecular, pharmacological and functional diversity of 5-HT receptors

Hoyer, D., Hannon, J. P., & Martin, G. R. (2014)

Molecular, pharmacological and functional diversity of 5-HT receptors

Hoyer, D., Hannon, J. P., & Martin, G. R. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00746-8 · Cited by 1,898

Classification and signaling characteristics of 5-HT receptors: toward the concept of 5-HT receptosomes

Marin, P., Bécamel, C., Chaumont‐Dubel, S., Vandermoere, F., Bockaert, J., & Claeysen, S. (2020) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-444-64125-0.00005-0 · Cited by 36