Chronic interleukin-6 (IL-6) treatment increased IL-6 secretion and induced insulin resistance in adipocyte: prevention by rosiglitazone

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

Hotamisligil, G. S., Shargill, N. S., & Spiegelman, B. M. (1993) · Science · doi:10.1126/science.7678183 · Cited by 7,518

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.

Hotamisligil, G. S., Arner, P., Caro, J. F., Atkinson, R. L., & Spiegelman, B. M. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117936 · Cited by 3,543

IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance

Hotamisligil, G. S., Peraldi, P., Budavari, A., Ellis, R., White, M. F., & Spiegelman, B. M. (1996) · Science · doi:10.1126/science.271.5249.665 · Cited by 2,630

A family of cytokine-inducible inhibitors of signalling

Starr, R., Willson, T. A., Viney, E. M., Murray, L. J. L., Rayner, J. R., Jenkins, B. J., Gonda, T. J., Alexander, W. S., Metcalf, D., Nicola, N. A., et al. (1997) · Nature · doi:10.1038/43206 · Cited by 2,066

Subcutaneous Adipose Tissue Releases Interleukin-6, But Not Tumor Necrosis Factor-α,in Vivo1

Mohamed‐Ali, V., Goodrick, S., Rawesh, A., Katz, D. R., Miles, J. M., Yudkin, J. S., Klein, S., & Coppack, S. W. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.12.4450 · Cited by 2,032

Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance

Kern, P. A., Ranganathan, S., Li, C., Wood, L., & Ranganathan, G. (2001) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2001.280.5.e745 · Cited by 1,883

Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?

Yudkin, J. S., Kumari, M., Humphries, S. E., & Mohamed-Ali, V. (2000) · Atherosclerosis · doi:10.1016/s0021-9150(99)00463-3 · Cited by 1,775

Omental and Subcutaneous Adipose Tissues of Obese Subjects Release Interleukin-6: Depot Difference and Regulation by Glucocorticoid

Fried, S. K., Bunkin, D. A., & Greenberg, A. S. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.3.4660 · Cited by 1,756

PPAR-gamma: adipogenic regulator and thiazolidinedione receptor.

Spiegelman, B. M. (1998) · Diabetes · doi:10.2337/diabetes.47.4.507 · Cited by 1,730

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

Taga, T., Hibi, M., Hirata, Y., Yamasaki, K., Yasukawa, K., Matsuda, T., Hirano, T., & Kishimoto, T. (1989) · Cell · doi:10.1016/0092-8674(89)90438-8 · Cited by 1,396

High pulse pressure is related to risk of type 2 diabetes mellitus in Chinese middle-aged females

Zhang, L., Wang, B., Wang, C., Li, L., Ren, Y., Zhang, H., Yang, X., Zhao, Y., Han, C., Zhou, J., et al. (2016) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.06.233 · Cited by 26

Reversal of Inflammation‐Induced Impairment of Glucose Uptake in Adipocytes by Direct Effect of CB1 Antagonism on Adipose Tissue Macrophages

Miranville, A., Herling, A. W., Biemer‐Daub, G., & Voss, M. D. (2010) · Obesity · doi:10.1038/oby.2010.81 · Cited by 26

Superantigen activates the gp130 receptor on adipocytes resulting in altered adipocyte metabolism

Banke, E., Rödström, K. E. J., Ekelund, M., Dalla‐Riva, J., Lagerstedt, J. O., Nilsson, S., Degerman, E., Lindkvist‐Petersson, K., & Nilson, B. (2014) · Metabolism · doi:10.1016/j.metabol.2014.03.004 · Cited by 26

Sterculic Oil, a Natural SCD1 Inhibitor, Improves Glucose Tolerance in Obese ob/ob Mice

Ortinau, L. C., Pickering, R. T., Nickelson, K. J., Stromsdorfer, K. L., Naik, C., Haynes, R. A., Bauman, D. E., Rector, R. S., Fritsche, K. L., & Perfield, J. W. (2012) · ISRN Endocrinology · doi:10.5402/2012/947323 · Cited by 27

Prostaglandin D2 and J2-series (PGJ2, Δ12-PGJ2) prostaglandins stimulate IL-6 and MCP-1, but inhibit leptin, expression and secretion by 3T3-L1 adipocytes

Peeraully, R., Sievert, H., Bulló, M., Wang, B., & Trayhurn, P. (2006) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-006-0118-x · Cited by 25

Diet and Diet Combined with Chronic Aerobic Exercise Decreases Body Fat Mass and Alters Plasma and Adipose Tissue Inflammatory Markers in Obese Women

Lakhdar, N., Denguezli, M., Zaouali, M., Zbidi, A., Tabka, Z., & Bouassida, A. (2013) · Inflammation · doi:10.1007/s10753-013-9661-8 · Cited by 25

A Potential Role for Pro-Inflammatory Cytokines in the Development of Insulin Resistance in Horses

Suagee, J. K., Corl, B. A., & Geor, R. J. (2012) · Animals · doi:10.3390/ani2020243 · Cited by 25

Obésité, inflammation et insulinorésistance : quel rôle pour les adipokines ?

Antuna-Puente, B. P., Fève, B., Fellahi, S., & Bastard, J. (2007) · Therapies · doi:10.2515/therapie:2007055 · Cited by 25

Reduced Slc2a4/GLUT4 expression in subcutaneous adipose tissue of monosodium glutamate obese mice is recovered after atorvastatin treatment

Poletto, A. C., David-Silva, A., Yamamoto, A. P. D. M., Machado, U. F., & Furuya, D. T. (2015) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-015-0015-6 · Cited by 25

CXCL13 is a differentiation- and hypoxia-induced adipocytokine that exacerbates the inflammatory phenotype of adipocytes through PHLPP1 induction

Kusuyama, J., Bandow, K., Ohnishi, T., Amir, M. S., Shima, K., Semba, I., & Matsuguchi, T. (2019) · Biochemical Journal · doi:10.1042/bcj20190709 · Cited by 25

SOCS and diabetes—ups and downs of a turbulent relationship

Suchy, D., Łabuzek, K., Machnik, G., Kozłowski, M., & Okopień, B. (2013) · Cell Biochemistry and Function · doi:10.1002/cbf.2940 · Cited by 27

Les relations entre obésité, inflammation et insulinorésistance : acquisitions récentes

Fève, B., Bastard, J., & Vidal, H. (2006) · Comptes Rendus Biologies · doi:10.1016/j.crvi.2006.03.020 · Cited by 33

[Studies on the active constituents of Momordica charantia L].

Zhu, Z. J., Zhong, Z. C., Luo, Z. Y., & Xiao, Z. Y. (1990) · PubMed · Cited by 25

Association between high body mass index and prognosis of patients with early-stage breast cancer: A systematic review and meta-analysis

Li, Z., Shen, G., Shi, M., Zheng, Y., Guan, Y., Xin, Y., Wang, M., Zhao, F., Ren, D., & Zhao, J. (2023) · Cancer Pathogenesis and Therapy · doi:10.1016/j.cpt.2023.03.002 · Cited by 26

Interleukin-6 Downregulates the Expression of Vascular Endothelial-Cadherin and Increases Permeability in Renal Glomerular Endothelial Cells via the Trans-Signaling Pathway

Yang, Y., Fu, H., Zhang, B., & Wu, Y.-B. (2022) · Inflammation · doi:10.1007/s10753-022-01711-3 · Cited by 24

Correlation of insulin resistance, beta cell function and insulin sensitivity with serum sFas and sFasL in newly diagnosed type 2 diabetes

Kumar, H., Mishra, M., Bajpai, S., Pokhria, D., Arya, A. K., Singh, R. K., & Tripathi, K. (2011) · Acta Diabetologica · doi:10.1007/s00592-011-0307-8 · Cited by 24

The Role of Inflammatory Pathway Genetic Variation on Maternal Metabolic Phenotypes during Pregnancy

Urbanek, M., Hayes, M. G., Lee, H., Freathy, R. M., Lowe, L. P., Ackerman, C. M., Jafari, N., Dyer, A. R., Cox, N. J., Dunger, D. B., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0032958 · Cited by 25

Partial sequencing and expression of genes involved in glucose metabolism in adipose tissues and skeletal muscle of healthy cats

Zini, E., Linscheid, P., Franchini, M., Kaufmann, K., Monnais, E., Kutter, A. P. N., Ackermann, M., Lutz, T. A., & Reusch, C. E. (2007) · The Veterinary Journal · doi:10.1016/j.tvjl.2007.10.022 · Cited by 24

Anti- and non-tumor necrosis factor-α-targeted therapies effects on insulin resistance in rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis

Wang, C., & Tsai, H. (2021) · World Journal of Diabetes · doi:10.4239/wjd.v12.i3.238 · Cited by 25

Activation of opioid μ-receptors by loperamide to improve interleukin-6-induced inhibition of insulin signals in myoblast C2C12 cells

Tzeng, T. F., Liu, I.-M., & Cheng, J. (2005) · Diabetologia · doi:10.1007/s00125-005-1791-6 · Cited by 23

Daidzein improves insulin resistance in ovariectomized rats

Cao, Y., Zhang, S. F., Zou, S., & Xia, X. (2012) · Climacteric · doi:10.3109/13697137.2012.664831 · Cited by 22

Exercise-mediated IL-6 signaling occurs independent of inflammation and is amplified by training in mouse adipose tissue

Castellani, L. N., Perry, C. G. R., MacPherson, R. E. K., Root-McCaig, J., Huber, J. S., Arkell, A. M., Simpson, J. A., & Wright, D. C. (2015) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00551.2015 · Cited by 22

Adipokines may mediate the relationship between resting metabolic rates and bone mineral densities in obese women

Moradi, S., Mirzaei, K., Abdurahman, A. A., & Keshavarz, S. A. (2017) · Osteoporosis International · doi:10.1007/s00198-017-3914-6 · Cited by 22

Liver Injury and Acute Liver Failure After Bariatric Surgery

Moolenaar, L. R., de Waard, N. E., Heger, M., de Haan, L. R., Slootmaekers, C. P. J., Nijboer, W. N., Tushuizen, M. E., & van Golen, R. F. (2022) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0000000000001662 · Cited by 22

The complex effects of adipokines in the patients with kidney disease

Vahdat, S. (2018) · Journal of Research in Medical Sciences · doi:10.4103/jrms.jrms_1115_17 · Cited by 21

Paradoxical resistance to high-fat diet-induced obesity and altered macrophage polarization in mineralocorticoid receptor-overexpressing mice

Kuhn, E., Bourgeois, C., Keo, V., Viengchareun, S., Muscat, A., Méduri, G., Menuet, D. L., Fève, B., & Lombès, M. (2013) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00323.2013 · Cited by 23

Growth Hormone Is Necessary for the p53-Mediated, Obesity-Induced Insulin Resistance in Male C57BL/6J × CBA Mice

Bogazzi, F., Raggi, F., Russo, D., Bohlooly‐Y, M., Sardella, C., Urbani, C., Lombardi, M., Manetti, L., Lupi, I., Törnell, J., et al. (2013) · Endocrinology · doi:10.1210/en.2013-1220 · Cited by 20

Thiazolidinediones

Reynolds, K., & Goldberg, R. B. (2006) · Treatments in Endocrinology · doi:10.2165/00024677-200605010-00004 · Cited by 20

Oligonol, an oligomerized lychee fruit-derived polyphenol, activates the Ras/Raf-1/MEK1/2 cascade independent of the IL-6 signaling pathway in rat primary adipocytes

Ogasawara, J., Kitadate, K., Nishioka, H., Fujii, H., Sakurai, T., Kizaki, T., Izawa, T., Ishida, H., Tanno, M., & Ohno, H. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.10.082 · Cited by 19

Adipokines and the signaling role of adipose tissue in inflammation and obesity

Wood, I. S., & Trayhurn, P. (2006) · Future Lipidology · doi:10.2217/17460875.1.1.81 · Cited by 18

Insulin use in chronic kidney disease and the risk of hypoglycemic events

Grube, D., Wei, G., Boucher, R. E., Abraham, N., Zhou, N., Gonce, V., Carle, J., Simmons, D. L., & Beddhu, S. (2022) · BMC Nephrology · doi:10.1186/s12882-022-02687-w · Cited by 19

Insights in diabetes: Molecular mechanisms-Protectin DX, an anti-inflammatory and a stimulator of inflammation resolution metabolite of docosahexaenoic acid, protects against the development of streptozotocin-induced type 1 and type 2 diabetes mellitus in male Swiss albino mice

Rengachar, P., Polavarapu, S., & Das, U. N. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.1053879 · Cited by 17

Antihypertensive therapy improves insulin resistance and serum levels of interleukin-6 and −10 in spontaneously hypertensive rats with steatohepatitis

Kozono, M., Uto, H., Ibusuki, R., Arima, S., Oda, K., Taguchi, H., Sasaki, F., Nasu, Y., Hashimoto, S., Setoyama, H., et al. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.5875 · Cited by 17

Anti-inflammatory effect of self-emulsifying delivery system containing Sonchus oleraceus Linn extract on streptozotocin-induced diabetic rats

Chen, L., Lin, X., Xu, X., Wang, L., Teng, H., & Cao, H. (2019) · Food and Chemical Toxicology · doi:10.1016/j.fct.2019.110953 · Cited by 17

La fonction sécrétrice du tissu adipeux : implication dans les complications métaboliques et cardiovasculaires de l'obésité

Guerre-Millo, M. (2006) · Journal de la Société de Biologie · doi:10.1051/jbio:2006005 · Cited by 16

Mitigation of isolation-associated adipocyte interleukin-6 secretion following rapid dissociation of adipose tissue

Thompson, A. C. S., Nuñez, M., Davidson, R. D., Horm, T. M., Schnittker, K., Hart, M. V., Suarez, A. M., & Tsao, T. (2012) · Journal of Lipid Research · doi:10.1194/jlr.d031286 · Cited by 16

Prognostic Impact of Baseline High-Sensitivity C-Reactive Protein in Patients With Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention Based on Body Mass Index

Ahmed, K., Jeong, M. H., Chakraborty, R., Cho, K. H., Sim, D. S., Hong, Y. J., Ahn, Y., Hachinohe, D., Cho, M., Kim, C. J., et al. (2012) · Korean Circulation Journal · doi:10.4070/kcj.2012.42.3.164 · Cited by 16

Cytokine-mediated inflammation is independently associated with insulin sensitivity measured by the euglycemic insulin clamp in a community-based cohort of elderly men.

Basu, S., Zethelius, B., Helmersson, J., Berne, C., Larsson, A. O., & Ärnlöv, J. (2011) · PubMed Central · Cited by 16

Chronic and Transient Hyperglycemia Induces Changes in the Expression Patterns of IL6 and ADIPOQ Genes and Their Associated Epigenetic Modifications in Differentiating Human Visceral Adipocytes

Wróblewski, A. M., Strycharz, J., Świderska, E., Balcerczyk, A., Szemraj, J., Drzewoski, J., & Śliwińska, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22136964 · Cited by 15

Predictors of the early impairment of renal disease in human obesity

Gilardini, L., Zulian, A., Girola, A., Redaelli, G., Conti, A., & Invitti, C. (2009) · International Journal of Obesity · doi:10.1038/ijo.2009.227 · Cited by 15

Beta-cell specific production of IL6 in conjunction with a mainly intracellular but not mainly surface viral protein causes diabetes

Belle, T. L. V., Pagni, P. P., Liao, J., Sachithanantham, S., Dave, A., Hani, A. B., Manenkova, Y., Amirian, N., Yang, C., Morin, B., et al. (2014) · Journal of Autoimmunity · doi:10.1016/j.jaut.2014.02.002 · Cited by 14

Decreased Levels of Proapoptotic Factors and Increased Key Regulators of Mitochondrial Biogenesis Constitute New Potential Beneficial Features of Long-lived Growth Hormone Receptor Gene-Disrupted Mice

Gesing, A., Masternak, M. M., Lewiñski, A., Karbownik‐Lewińska, M., Kopchick, J. J., & Bartke, A. (2012) · The Journals of Gerontology Series A · doi:10.1093/gerona/gls231 · Cited by 14

ANTI-DIABETIC EFFECTS OF ZHUODUQING FORMULA, A CHINESE HERBAL DECOCTION, ON A RAT MODEL OF TYPE 2 DIABETES

Feng, X., Tang, S.-Y., Jiang, Y., & Zhao, W. (2017) · African Journal of Traditional Complementary and Alternative Medicines · doi:10.21010/ajtcam.v14i3.5 · Cited by 14

Rosiglitazone regulates IL-6-stimulated lipolysis in porcine adipocytes

Yang, Y., & Yang, G. (2010) · Biochemistry and Cell Biology · doi:10.1139/o10-116 · Cited by 13

Arsenic and diabetes mellitus: a putative role for the immune system

Liu, J., Hermon, T., Gao, X., Dixon, D., & Xiao, H. (2023) · All Life · doi:10.1080/26895293.2023.2167869 · Cited by 12

An improved in vitro 3T3-L1 adipocyte model of inflammation and insulin resistance

Odeniyi, I. A., Ahmed, B., Anbiah, B., Hester, G., Abraham, P., Lipke, E. A., & Greene, M. W. (2024) · Adipocyte · doi:10.1080/21623945.2024.2414919 · Cited by 13

Down-regulating Interleukin-22/Interleukin-22 binding protein axis promotes inflammation and aggravates diet-induced metabolic disorders

Gu, J., Zhou, P., Liu, Y., Xu, Q., Chen, X., Chen, M., Chen, L., Qu, C., Tong, Y., Yu, Q., et al. (2022) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2022.111776 · Cited by 13

The Role of Organokines in Obesity and Type 2 Diabetes and Their Functions as Molecular Transducers of Nutrition and Exercise

Lim, J. Y., & Kim, E. (2023) · Metabolites · doi:10.3390/metabo13090979 · Cited by 13

The emerging role of the gut microbiome in polycystic ovary syndrome

He, Y., Jin, X., Wang, H., Dai, H., Lu, X., Zhao, J., Zhang, H., Chen, W., & Wang, G. (2021) · F&S Reviews · doi:10.1016/j.xfnr.2021.03.003 · Cited by 14

Interleukin 6 acutely increases gluconeogenesis and decreases the suppressive effect of insulin on cAMP‐stimulated glycogenolysis in rat liver

Biazi, G. R., Frasson‐Uemura, I. G., Miksza, D. R., Ferraz, L. S., Diaz, B. F., Bertolini, G. L., & de Souza, H. M. (2023) · Cell Biochemistry and Function · doi:10.1002/cbf.3817 · Cited by 13

Regulation of Appetite and Insulin Signaling in Inflammatory States

TELI, T., XANTHAKI, D., & Karalis, K. P. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1367.022 · Cited by 12

Myokines: Do they really exist?

Manabe, Y., Miyatake, S., & Takagi, M. (2012) · The Journal of Physical Fitness and Sports Medicine · doi:10.7600/jpfsm.1.51 · Cited by 11

Is the canine corpus luteum an insulin-sensitive tissue?

Sousa, L. M. M. D. C., Silva, R. D. S., da Fonseca, V. U., Leandro, R. M., Vincenzo, T. S., Alves-Wagner, A. B., Machado, U. F., & Papa, P. D. C. (2016) · Journal of Endocrinology · doi:10.1530/joe-16-0173 · Cited by 11

Inflammatory Response, a Key Pathophysiological Mechanism of Obesity-Induced Depression

Shao, S., Liu, D.-Q., Zhang, B., & Huang, S.-M. (2020) · Mediators of Inflammation · doi:10.1155/2020/8893892 · Cited by 12

Interleukins in adipose tissue: Keeping the balance

Antuna-Puente, B., Fellahi, S., McAvoy, C., Fève, B., & Bastard, J. (2021) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2021.111531 · Cited by 11

Efficient adenoviral transduction of 3T3-F442A preadipocytes without affecting adipocyte differentiation

Béréziat, V., Moritz, S., Klonjkowski, B., Decaudain, A., Auclair, M., Éloit, M., Capeau, J., & Vigouroux, C. (2005) · Biochimie · doi:10.1016/j.biochi.2005.05.010 · Cited by 10

Role of amyloid β in the induction of lipolysis and secretion of adipokines from human adipose tissue

Wan, Z., Mah, D., Simtchouk, S., Kluftinger, A., & Little, J. P. (2014) · Adipocyte · doi:10.4161/21623945.2014.985020 · Cited by 9

Prednisolone induces the Wnt signalling pathway in 3T3-L1 adipocytes

Fleuren, W., Linssen, M. M. L., Toonen, E. J. M., van der Zon, G. C. M., Guigas, B., de Vlieg, J., Dokter, W. H. A., Ouwens, D. M., & Alkema, W. B. L. (2013) · Archives of Physiology and Biochemistry · doi:10.3109/13813455.2013.774022 · Cited by 9

Dietary caloric restriction modifies inflammatory responses in the livers of streptozotocin-induced diabetic rats

Ugochukwu, N. H., & Figgers, C. L. (2006) · Nutrition Research · doi:10.1016/j.nutres.2006.05.003 · Cited by 8

Plasminogen activator inhibitor-1 expression and secretion are stimulated by growth hormone and interleukin-6 in 3T3-L1 adipocytes

Kralisch, S., Klein, J. C., Lössner, U., Blüher, M., Paschke, R., Stümvoll, M., & Faßhauer, M. (2006) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2006.04.027 · Cited by 8

Deletion of growth hormone receptor gene but not visceral fat removal decreases expression of apoptosis-related genes in the kidney—potential mechanism of lifespan extension

Gesing, A., Masternak, M. M., Wang, F., Karbownik‐Lewińska, M., & Bartke, A. (2011) · AGE · doi:10.1007/s11357-011-9232-6 · Cited by 7

Dietary fish oil ameliorates adipose tissue dysfunction in insulin-resistant rats fed a sucrose-rich diet improving oxidative stress, peroxisome proliferator-activated receptor γ and uncoupling protein 2

Selenscig, D. A., Ferreira, M. D. R., Chicco, A. G., & Lombardo, Y. B. (2018) · Food & Function · doi:10.1039/c7fo01993a · Cited by 7

Menstrual variation of autonomic balance may be a factor in exacerbations of certain diseases during the menstrual cycle

Lee, P. Y., Bazar, K. A., & Yun, A. J. (2004) · Medical Hypotheses · doi:10.1016/j.mehy.2004.02.036 · Cited by 7

Insulin Resistance in SHR/NDmc-cp Rats Correlates with Enlarged Perivascular Adipocytes and Endothelial Cell Dysfunction in Skeletal Muscle

Hariya, N., Mochizuki, K., Inoue, S., Morioka, K., Shimada, M., Okuda, T., & Goda, T. (2014) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.60.52 · Cited by 6

Non-Alcoholic Fatty Steatohepatitis an Inflammatory Disorder Beyond the Liver

Cerpa‐Cruz, S. (2013) · Journal of Clinical & Cellular Immunology · doi:10.4172/2155-9899.1000159 · Cited by 6

The Modulation of PPARγ1 and PPARγ2 mRNA Expression by Ciglitazone in CD3/CD28-Activated Naïve and Memory CD4+ T Cells

Norazmi, M. N., Mohamed, R., Nurul, A. A., & Yaacob, N. S. (2012) · Clinical and Developmental Immunology · doi:10.1155/2012/849195 · Cited by 6

Behavioral risk factors and effects of lifestyle modification on adults with diabetes: a Brazilian community-based study

Burini, R. C., Torezan, G. A., Portero, K. C. D. C., & McLellan, K. C. P. (2013) · Acervo Digital da Universidade Estadual Paulista (Universidade Estadual Paulista) · Cited by 6

The interplay between asthma and type 2 diabetes mellitus: mutual interactions and therapeutic implications

Cazzola, M., Hanania, N. A., Page, C. P., Calzetta, L., Matera, M. G., & Rogliani, P. (2025) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2025.2514607 · Cited by 5

Modeling Adipokine and Insulin‐Mediated Crosstalk Between Adipocytes and Beta Cells Using Flow‐Enabled Microfluidics

Orabi, M., Yeganeh, M. S., Chun, T., & Lo, J. F. (2025) · Small · doi:10.1002/smll.202504686 · Cited by 4

Dolutegravir-associated hyperglycemia: a narrative review

Buzibye, A., Castelnuovo, B., Bollinger, R. C., Ssebulime, J., Omali, D., Muller, D., Mulindwa, F., Laker, E. A. O., Waitt, C. J., Andia, I., et al. (2025) · AIDS Research and Therapy · doi:10.1186/s12981-025-00800-1 · Cited by 5

Adipocytes promote metastasis of breast cancer by attenuating the FOXO1 effects and regulating copper homeostasis

Chen, X., Zhang, H., Fang, Z., Wang, D., Song, Y., Zhang, Q., Hou, J., Yang, S., Xu, D., Fei, Y., et al. (2024) · Cancer Cell International · doi:10.1186/s12935-024-03433-y · Cited by 5

Renal pro-apoptotic proteins are reduced by growth hormone resistance but not by visceral fat removal

Gesing, A., Bartke, A., Wang, F., Karbownik‐Lewińska, M., & Masternak, M. M. (2011) · Biological Chemistry · doi:10.1515/bc.2011.051 · Cited by 5

Thiazolidinediones and vascular damage

Goldberg, R. B. (2007) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0b013e328054c655 · Cited by 5

Combined effect of C-reactive protein and stavudine on adipogenesis

Stankov, M. V., Schmidt, R. E., & Behrens, G. M. N. (2008) · Antiviral Therapy · doi:10.3851/imp1296 · Cited by 5

A cross-sectional study of serum lipids, body mass index and age relationships with breast cancer risk

Hu, Y., & Yang, S. (2025) · World Journal of Surgical Oncology · doi:10.1186/s12957-025-03817-y · Cited by 4

Neurolytic celiac plexus block enhances skeletal muscle insulin signaling and attenuates insulin resistance in GK rats

Li, J., CHEN, T., Li, K., Yan, H.-T., Li, X., Yang, Y. C., Zhang, Y., Su, B., & Li, F. (2016) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2016.3087 · Cited by 4

Neuroprotective effects of antenatal magnesium sulfate under inflammatory conditions in a Sprague–Dawley pregnant rat model*

Binette, A., Blouin, S., Ardilouze, A., & Pasquier, J. (2016) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2016.1223031 · Cited by 4

Caspase-1 Deficiency Modulates Adipogenesis through Atg7-Mediated Autophagy: An Inflammatory-Independent Mechanism

Wang, Y., Chen, G., Xu, M., Cui, Y., He, W., Zeng, H., Zeng, T., Cheng, R., & Li, X. (2024) · Biomolecules · doi:10.3390/biom14040501 · Cited by 6

Impaired suppression of fatty acid release by insulin is a strong predictor of reduced whole‐body insulin‐mediated glucose uptake and skeletal muscle insulin receptor activation

Schleh, M. W., Ryan, B. J., Ahn, C., Ludzki, A. C., Pelt, D. W. V., Pitchford, L. M., Chugh, O. K., Luker, A. T., Luker, K. E., Samovski, D., et al. (2024) · Acta Physiologica · doi:10.1111/apha.14249 · Cited by 5

IL-4 and IL-6 levels and adipose tissue distribution in HIV-1 patients under antiretroviral therapy

Belo, S., Santos, A. C., Madureira, A. J., Pereira, J., Sarmento, A., Carvalho, D. M., & Freitas, P. (2015) · Journal of Endocrinological Investigation · doi:10.1007/s40618-015-0256-0 · Cited by 4

Dietary Supplementation with α-Amylase Inhibitor Wheat Albumin to High-Fat Diet-Induced Insulin-Resistant Rats Is Associated with Increased Expression of Genes Related to Fatty Acid Synthesis in Adipose Tissue

Murayama, Y., Mochizuki, K., Shimada, M., Fujimoto, S., Nukui, K., Shibata, K., & Goda, T. (2009) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf901484t · Cited by 4

Effect of interleukin‐6 receptor blockade on feto‐maternal outcomes in a rat model of intrauterine inflammation

Ouellet, J., Berthiaume, M., Corriveau, S., Rola‐Pleszczynski, M., & Pasquier, J. (2013) · Journal of obstetrics and gynaecology research · doi:10.1111/jog.12089 · Cited by 4

Felodipine downregulates serum interleukin-18 levels in rats with fructose-induced metabolic syndrome

Bi, X., Tan, H., Xing, S. S., Zhong, M., Zhang, Y., & Zhang, W. (2009) · Journal of Endocrinological Investigation · doi:10.1007/bf03345716 · Cited by 4

Methyl-β-cyclodextrin alters adipokine gene expression and glucose metabolism in swine adipose tissue

Ramsay, T. G., Blomberg, L. A., & Caperna, T. J. (2013) · animal · doi:10.1017/s1751731113001250 · Cited by 4

Diet and diet combined with chronic aerobic exercise decreases body fat mass and alters plasma and adipose tissue inflammatory markers in obese women

Lakhdar, N., Denguezli, M., Zaouali, M., Zbidi, A., Tabka, Z., & Bouassida, A. (2015) · Pediatric Rheumatology · doi:10.1186/1546-0096-13-s1-p194 · Cited by 4

The Relationship Among Obesity, Inflammation, and Insulin Resistance

Bastard, J., & Fève, B. (2013) · Wiley eBooks · doi:10.1002/9781118395318.ch17 · Cited by 4

Regulation of Staphylococcal Enterotoxin-Induced Inflammation in Spleen Cells from Diabetic Mice by Polyphenols

Shimamura, Y., Noaki, R., Oura, Y., Ichikawa, K., Kan, T., & Masuda, S. (2023) · Microorganisms · doi:10.3390/microorganisms11041039 · Cited by 3

Molecular cloning, expression and regulation analysis of the interleukin-6 (IL-6) gene in goose adipocytes

Wang, F., Tian, Y., Li, G., Chen, X., Yuan, H. Y., Wang, D., Li, J., Shen, J., Tao, Z., Fu, Y., et al. (2012) · British Poultry Science · doi:10.1080/00071668.2012.746639 · Cited by 3

Kinase-dependent pathways and the development of insulin resistance in hepatocytes

Rondinone, C. M. (2007) · Expert Review of Endocrinology & Metabolism · doi:10.1586/17446651.2.2.195 · Cited by 4

Effect of Vitamin D Supplementation on Inflammatory Markers in Obese Patients with Acute and Chronic Orthopedic Conditions

Gawryjołek, M., Wiciński, M., Zabrzyńska, M., Ohla, J., & Zabrzyński, J. (2024) · Nutrients · doi:10.3390/nu16213735 · Cited by 2

Multidimensional risk impact of obesity on breast cancer incidence, treatment, and prognosis

Liu, Y., Xu, S., Yang, H., & Wang, Y. (2026) · International Journal of Obesity · doi:10.1038/s41366-025-02008-9 · Cited by 2

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Dinatale, B., González, F. B., Bottasso, O., & Pérez, A. R. (2026) · Seminars in Immunology · doi:10.1016/j.smim.2026.102028 · Cited by 2

NAMPT, IL-6, and vaspin gene expressions and serum protein levels in type 2 diabetes mellitus and related complication

Çelik, S. P., Parıltı, D. N., Açık, L., Yalçın, M. M., Yetkin, İ., & Yunusov, E. (2024) · TURKISH JOURNAL OF BIOLOGY · doi:10.55730/1300-0152.2688 · Cited by 3

Obesity, Type 2 Diabetes and Cancer

Ferguson, R. D., & LeRoith, D. (2011) · Springer eBooks · doi:10.1007/978-1-4614-0598-6_3 · Cited by 2

Role of Adipokines in Controlling Insulin Signaling Pathways in Type-2 Diabetes and Obesity. Current and Future Perspectives

Bouzid, T., Hamel, F. G., & Lim, J. Y. (2016) · Cited by 2

Ameliorating effect of tocilizumab in letrozole induced polycystic ovarian syndrome in rats via improving insulin resistance and down-regulation of VEGF/ANGPT/PDGF

Ibrahim, Y. F., Toni, N. D. M., Thabet, K., Hegazy, A., & Bahaa, H. A. (2020) · Minia Journal of Medical Research · doi:10.21608/mjmr.2022.221583 · Cited by 2

Cytokines associated with insulin resistance in critically ill patients

Omar, S., Wilgen, U., & Crowther, N. J. (2007) · Critical Care · doi:10.1186/cc5280 · Cited by 2

Doramectin attenuates inflammation, obesity and insulin resistance in food-borne obese mice

Jin, T., Jia, J., Li, W., Wu, P., Liu, T., Luo, B., & Zhang, Z. (2024) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2024.150404 · Cited by 1

Addition of sitagliptin to ongoing metformin improved metabolic profile and pancreatic function via normalizing inflammatory cytokines’ levels in patients with type 2 diabetes, a randomized double-blinded clinical trial

Yaribeygi, H., Mirmohammadkhani, M., Rashidy‐Pour, A., Sathyapalan, T., Foroutan, M., Najmaldin, A., Hemmati, M. A., & Memaripanah, N. (2025) · Expert Review of Endocrinology & Metabolism · doi:10.1080/17446651.2025.2539252 · Cited by 1

MASLD and sarcopenia research (2012–2025): a multi-database bibliometric analysis

Gao, K., Xun, L., Hao, S., An, M., Zuo, L., Wang, J., Wang, Y., & He, J. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1834112 · Cited by 1

Interleukin-6 (IL-6) Induces Insulin Resistance in 3T3-L1 Adipocytes and Is, Like IL-8 and Tumor Necrosis Factor-α, Overexpressed in Human Fat Cells from Insulin-resistant Subjects

Rotter, V., Nagaev, I., & Smith, U. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m301977200 · Cited by 1,062

Rosiglitazone regulates IL-6-stimulated lipolysis in porcine adipocytes

Yang, Y., & Yang, G. (2010) · Biochemistry and Cell Biology · doi:10.1139/o10-116 · Cited by 13

Mechanism of interleukin-6 induced insulin resistance in 3T3-L1 adipocytes

Lulu, C. (2007) · Zhongguo bingli shengli zazhi

Interleukin-6 as a mediator of insulin resistance

Sopasakis, V. R. (2004) · Gothenburg University Publications Electronic Archive (Gothenburg University)

Adipose Tissue IL-6 Content Correlates with Resistance to Insulin Activation of Glucose Uptake both in Vivo and in Vitro

Bastard, J., Maachi, M., Nhieu, J. T. V., Jardel, C., Bruckert, É., Grimaldi, A., Robert, J., Capeau, J., & Hainque, B. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.5.8450 · Cited by 636