The DOI matches its Crossref record; 125 of the 125 references it cites were found in a registry or an index.
The emergence of COVID-19 as a global pandemic: Understanding the epidemiology, immune response and potential therapeutic targets of SARS-CoV-2
Open accessAbstract
An acute respiratory disease caused by a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that surfaced in China in late 2019, continues to spread rapidly across the globe causing serious concerns. The coronavirus disease 2019 (COVID-19) is declared as a public health emergency worldwide by the World Health Organization (WHO). Increasing evidences have demonstrated human-to-human transmission that primarily affects the upper respiratory tract followed by lower respiratory tract damage leading to severe pneumonia. Based on the current status, the elderly population and people with prior co-morbidities are highly susceptible to serious health effects including cytokine up-regulation and acute respiratory distress syndrome (ARDS). Currently, COVID-19 research is still in the preliminary stage necessitating rigorous studies. There is no specific drug or vaccine targeting SARS-CoV-2 currently and only symptomatic treatment is being administered, but several antivirals are under active investigation. In this review, we have summarized the epidemiology, entry mechanism, immune response, and therapeutic implications, possible drug targets, their ongoing clinical trials, and put forward vital questions to offer new directions to the COVID-19 research.
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Cites
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
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A novel coronavirus from patients with pneumonia in China, 2019
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A pneumonia outbreak associated with a new coronavirus of probable bat origin
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La certeza de lo impredecible: Cultura Educación y Sociedad en tiempos de COVID19
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Cited by
The impact of the COVID-19 pandemic on maternal and perinatal health: a scoping review
Kotlar, B., Gerson, E. M., Petrillo, S., Langer, A., & Tiemeier, H. (2021) · Reproductive Health · doi:10.1186/s12978-021-01070-6 · Cited by 758
Zidan, N., Dey, V., Allen, K., Price, J., Zappone, S. R., Hebert, C., Schleyer, T., & Ning, X. (2023) · JAMIA Open · doi:10.1093/jamiaopen/ooad002 · Cited by 11
Kyaw, M. H., Spinardi, J. R., Jagun, O., Franco Villalobos, C., Kapetanakis, V., Sharf-Williams, R., & Yarnoff, B. (2024) · BMJ Open · doi:10.1136/bmjopen-2023-081019 · Cited by 6
Metadata
- Authors
- Muralidar, S., Ambi, S. V., Sekaran, S., & Krishnan, U. M.
- Venue
- Biochimie
- Publisher
- Elsevier BV
- Published
- 2020-12
- Volume
- 179
- Pages
- 85-100
- ISSN
- 0037-9042 (ISSN-L)
- 0300-9084
- OpenAlex
- W3087600780
- Cited by
- 346
- References
- 125
- FWCI
- 5.88
- Type
- journal article
- Language
- en
- Open access
- green
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- Muralidar, S., Ambi, S. V., Sekaran, S., & Krishnan, U. M. (2020). The emergence of COVID-19 as a global pandemic: Understanding the epidemiology, immune response and potential therapeutic targets of SARS-CoV-2. Biochimie. https://doi.org/10.1016/j.biochi.2020.09.018
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
