FGF-2 and VEGF functionalization of starPEG–heparin hydrogels to modulate biomolecular and physical cues of angiogenesis

Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering

Lutolf, M. P., & Hubbell, J. A. (2005) · Nature Biotechnology · doi:10.1038/nbt1055 · Cited by 4,551 · see citing works

Angiogenesis in life, disease and medicine

Carmeliet, P. (2005) · Nature · doi:10.1038/nature04478 · Cited by 3,494 · see citing works

Growth Factors, Matrices, and Forces Combine and Control Stem Cells

Discher, D. E., Mooney, D. J., & Zandstra, P. W. (2009) · Science · doi:10.1126/science.1171643 · Cited by 2,666 · see citing works

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

Yayon, A., Klagsbrun, M., Esko, J. D., Leder, P., & Ornitz, D. M. (1991) · Cell · doi:10.1016/0092-8674(91)90512-w · Cited by 2,440 · see citing works

Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion

Yeung, T., Georges, P. C., Flanagan, L. A., Marg, B., Ortiz, M., Funaki, M., Zahir, N., Ming, W., Weaver, V., & Janmey, P. A. (2005) · Cell Motility and the Cytoskeleton · doi:10.1002/cm.20041 · Cited by 2,325 · see citing works

Vascular Endothelial Growth Factor and Angiogenesis

Hoeben, A., Landuyt, B., Highley, M. S., Wildiers, H., Van Oosterom, A. T., & De Bruijn, E. A. (2004) · Pharmacological Reviews · doi:10.1124/pr.56.4.3 · Cited by 1,824 · see citing works

On the importance and mechanisms of burst release in matrix-controlled drug delivery systems

Huang, X. B., & Brazel, C. S. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(01)00248-6 · Cited by 1,819 · see citing works

Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis

Presta, M., Dell’Era, P., Mitola, S. M. F., Moroni, E., Ronca, R., & Rusnati, M. (2005) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2005.01.004 · Cited by 1,257 · see citing works

An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide.

Jones, K. H., & Senft, J. A. (1985) · Journal of Histochemistry & Cytochemistry · doi:10.1177/33.1.2578146 · Cited by 1,104 · see citing works

Clinical applications of angiogenic growth factors and their inhibitors

Ferrara, N., & Alitalo, K. (1999) · Nature Medicine · doi:10.1038/70928 · Cited by 1,004 · see citing works

Growth factors in the extracellular matrix

Taipale, J., & Keski‐Oja, J. (1997) · The FASEB Journal · doi:10.1096/fasebj.11.1.9034166 · Cited by 916 · see citing works

Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: role of extracellular matrix.

Ingber, D. E., & Folkman, J. (1989) · The Journal of Cell Biology · doi:10.1083/jcb.109.1.317 · Cited by 864 · see citing works

Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro

Pepper, M. S., Ferrara, N., Orci, L., & Montesano, R. (1992) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(92)92277-5 · Cited by 856 · see citing works

Endothelial cell-derived heparan sulfate binds basic fibroblast growth factor and protects it from proteolytic degradation.

Saksela, O., Moscatelli, D., Sommer, A., & Rifkin, D. B. (1988) · The Journal of Cell Biology · doi:10.1083/jcb.107.2.743 · Cited by 803 · see citing works

Heparin Structure and Interactions with Basic Fibroblast Growth Factor

Faham, S., Hileman, R. E., Fromm, J. R., Linhardt, R. J., & Rees, D. C. (1996) · Science · doi:10.1126/science.271.5252.1116 · Cited by 798 · see citing works

Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors

Lee, S., Jilani, S. M., Nikolova, G. V., Carpizo, D. R., & Iruela‐Arispe, M. L. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200409115 · Cited by 704 · see citing works

The Carboxyl-terminal Domain(111–165) of Vascular Endothelial Growth Factor Is Critical for Its Mitogenic Potency

Keyt, B. A., Berleau, L. T., Nguyen, H. V., Chen, H., Heinsohn, H. G., VANDLEN, R. L., & Ferrara, N. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.13.7788 · Cited by 603 · see citing works

Development of fibrin derivatives for controlled release of heparin-binding growth factors

Sakiyama‐Elbert, S. E., & Hubbell, J. A. (2000) · Journal of Controlled Release · doi:10.1016/s0168-3659(99)00221-7 · Cited by 565 · see citing works

The binding of vascular endothelial growth factor to its receptors is dependent on cell surface-associated heparin-like molecules.

Gitay-Goren, H., Söker, S., Vlodavsky, I., & Neufeld, G. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42666-x · Cited by 490 · see citing works

Synergistic effects of vascular endothelial growth factor and basic fibroblast growth factor on the proliferation and cord formation of bovine capillary endothelial cells within collagen gels.

Goto, F., Goto, K., Weindel, K., & Folkman, J. (1993) · PubMed · Cited by 459 · see citing works

Vascular endothelial growth factor: Crystal structure and functional mapping of the kinase domain receptor binding site

Muller, Y. A., Li, B., Christinger, H. W., Wells, J. A., Cunningham, B. C., & de Vos, A. M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.14.7192 · Cited by 452 · see citing works

Injectable glycosaminoglycan hydrogels for controlled release of human basic fibroblast growth factor

Cai, S., Liu, Y., Shu, X. Z., & Prestwich, G. D. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.03.012 · Cited by 423 · see citing works

Controlled and modulated release of basic fibroblast growth factor

Edelman, E. R., Mathiowitz, E., Langer, R., & Klagsbrun, M. (1991) · Biomaterials · doi:10.1016/0142-9612(91)90107-l · Cited by 363 · see citing works

Matrices and scaffolds for protein delivery in tissue engineering

Teßmar, J., & Göpferich, A. M. (2007) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2007.03.020 · Cited by 346 · see citing works

The effect of sulfation of alginate hydrogels on the specific binding and controlled release of heparin-binding proteins

Freeman, I., Kedem, A., & Cohen, S. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.04.025 · Cited by 326 · see citing works

New materials for tissue engineering: towards greater control over the biological response

Chan, G., & Mooney, D. J. (2008) · Trends in biotechnology · doi:10.1016/j.tibtech.2008.03.011 · Cited by 307 · see citing works

Hybrid Multicomponent Hydrogels for Tissue Engineering

Jia, X., & Kiick, K. L. (2008) · Macromolecular Bioscience · doi:10.1002/mabi.200800284 · Cited by 305 · see citing works

A star-PEG–heparin hydrogel platform to aid cell replacement therapies for neurodegenerative diseases

Freudenberg, U., Hermann, A., Welzel, P. B., Stirl, K., Schwarz, S. C., Grimmer, M., Zieris, A., Panyanuwat, W., Zschoche, S., Meinhold, D., et al. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.06.002 · Cited by 300 · see citing works

Characterization of Growth Factor-binding Structures in Heparin/Heparan Sulfate Using an Octasaccharide Library

Ashikari‐Hada, S., Habuchi, H., Kariya, Y., Itoh, N., Reddi, A. H., & Kimata, K. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m313523200 · Cited by 296 · see citing works

Three-dimensional structure of human basic fibroblast growth factor.

Sauer-Eriksson, A. E., Cousens, L. S., Weaver, L. H., & Matthews, B. W. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.8.3441 · Cited by 284 · see citing works

Heparin increases the affinity of basic fibroblast growth factor for its receptor but is not required for binding.

Roghani, M., Mansukhani, A., Dell’Era, P., Bellosta, P., Basilico, C., Rifkin, D. B., & Moscatelli, D. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)41730-3 · Cited by 259 · see citing works

Differential Endothelial Migration and Proliferation to Basic Fibroblast Growth Factor and Vascular Endothelial Growth Factor

Yoshida, A., Anand‐Apte, B., & Zetter, B. R. (1996) · Growth Factors · doi:10.3109/08977199609034566 · Cited by 255 · see citing works

Improved endothelialization of vascular grafts by local release of growth factor from heparinized collagen matrices

Wissink, M., Beernink, R. H. J., Poot, A. A., et al. (2000) · Journal of Controlled Release · doi:10.1016/s0168-3659(99)00145-5 · Cited by 239 · see citing works

Maleic Anhydride CopolymersA Versatile Platform for Molecular Biosurface Engineering

Pompe, W., Zschoche, S., Herold, N., Salchert, K., Gouzy, M.-F., Sperling, C., & Werner, C. (2003) · Biomacromolecules · doi:10.1021/bm034071c · Cited by 236 · see citing works

Heparin functionalized PEG gels that modulate protein adsorption for hMSC adhesion and differentiation

Benoit, D. S. W., & Anseth, K. S. (2005) · Acta Biomaterialia · doi:10.1016/j.actbio.2005.03.002 · Cited by 231 · see citing works

Customized PEG‐Derived Copolymers for Tissue‐Engineering Applications

Teßmar, J., & Göpferich, A. M. (2006) · Macromolecular Bioscience · doi:10.1002/mabi.200600096 · Cited by 200 · see citing works

PEG-cross-linked heparin is an affinity hydrogel for sustained release of vascular endothelial growth factor

Tae, G., Scatena, M., Stayton, P. S., & Hoffman, A. S. (2005) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/156856206774879090 · Cited by 149 · see citing works

Engineering biomaterials to control cell function

Liu, W. F., & Chen, C. S. (2005) · Materials Today · doi:10.1016/s1369-7021(05)71222-0 · Cited by 138 · see citing works

Angiogenesis with biomaterial-based drug- and cell-delivery systems

Patel, Z. S., & Mikos, A. G. (2004) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/156856204774196117 · Cited by 138 · see citing works

Structural features in heparin that interact with VEGF165 and modulate its biological activity

Ono, K. (1999) · Glycobiology · doi:10.1093/glycob/9.7.705 · Cited by 118 · see citing works

Production of heparin-containing hydrogels for modulating cell responses

Nie, T., Akins, R. E., & Kiick, K. L. (2008) · Acta Biomaterialia · doi:10.1016/j.actbio.2008.12.004 · Cited by 94 · see citing works

Physical Polymer Matrices Based on Affinity Interactions between Peptides and Polysaccharides

Seal, B. L., & Panitch, A. (2003) · Biomacromolecules · doi:10.1021/bm0342032 · Cited by 93 · see citing works

Controlled release of heparin-binding growth factors using heparin-containing particulate systems for tissue regeneration

Joung, Y. K., Bae, J. W., & Park, K. D. (2008) · Expert Opinion on Drug Delivery · doi:10.1517/17425240802431811 · Cited by 91 · see citing works

Stoichiometry of Heparin Binding to Basic Fibroblast Growth Factor

Arakawa, T., Wen, J., & Philo, J. S. (1994) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1994.1037 · Cited by 57 · see citing works

Enzymatically degradable heparin-polyethylene glycol gels with controlled mechanical properties

Tsurkan, M. V., Levental, K. R., Freudenberg, U., et al. (2009) · Chemical Communications · doi:10.1039/b921616b · Cited by 51 · see citing works

Neprilysin Inhibits Angiogenesis via Proteolysis of Fibroblast Growth Factor-2

Goodman, O. B., Febbraio, M., Simantov, R., Zheng, R., Shen, R., Silverstein, R. L., & Nanus, D. M. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m602490200 · Cited by 50 · see citing works

Improved method of human umbilical arterial endothelial cell culture

Weis, J. R., Sun, B., & Rodgers, G. M. (1991) · Thrombosis Research · doi:10.1016/0049-3848(91)90245-r · Cited by 47 · see citing works

Quantitative analysis of immobilized proteins and protein mixtures by amino acid analysis

Salchert, K., Pompe, W., Sperling, C., et al. (2003) · Journal of Chromatography A · doi:10.1016/s0021-9673(03)00932-4 · Cited by 47 · see citing works

A comparison of the adhesion of mammalian cells andStaphylococcus epidermidis on fibronectin-modified polymer surfaces

Dexter, S. J., Pearson, R. G., Davies, M. C., C�mara, M., & Shakesheff, K. M. (2001) · Journal of Biomedical Materials Research · doi:10.1002/1097-4636(200108)56:2 · Cited by 35 · see citing works

Chemical Derivatization as a Strategy to Study Structure-Activity Relationships of Glycosaminoglycans

Casu, B., Naggi, A., & Torri, G. (2002) · Seminars in Thrombosis and Hemostasis · doi:10.1055/s-2002-34302 · Cited by 32 · see citing works

Analytical approaches to uptake and release of hydrogel-associated FGF-2

Zieris, A., Prokoph, S., Welzel, P. B., et al. (2009) · Journal of Materials Science Materials in Medicine · doi:10.1007/s10856-009-3913-z · Cited by 27 · see citing works

Polymeric Systems for Bioinspired Delivery of Angiogenic Molecules

Fischbach, C., & Mooney, D. J. (2006) · Springer eBooks · doi:10.1007/12_070 · Cited by 24 · see citing works

Purification of human plasma fibronectin

Brew, S. A., & Ingram, K. C. (1994) · Methods in Cell Science · doi:10.1007/bf01540650 · Cited by 23 · see citing works

Wound repair and regeneration: Mechanisms, signaling, and translation

Eming, S. A., Martin, P., & Tomic-Canic, M. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3009337 · Cited by 3,562 · see citing works

Incorporation of heparin into biomaterials

Sakiyama-Elbert, S. E. (2014) · Acta Biomaterialia · doi:10.1016/j.actbio.2013.08.045 · Cited by 222 · see citing works

A mini review on the functional biomaterials based on poly (lactic acid) stereocomplex

Jing, Y., Quan, C., Liu, B., Jiang, Q., & Zhang, C. (2016) · Polymer Reviews · doi:10.1080/15583724.2015.1111380 · Cited by 92 · see citing works

Bio-engineering a prevascularized human tri-layered skin substitute containing a hypodermis

Zimoch, J., Zielinska, D., Michalak-Micka, K., Rütsche, D., Böni, R., Biedermann, T., & Klar, A. S. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2021.07.033 · Cited by 57 · see citing works

Improved Angiogenesis in Response to Localized Delivery of Macrophage-Recruiting Molecules

Hsu, C.-W., Poché, R. A., Saik, J. E., Ali, S., Wang, S., Yosef, N., Calderon, G. A., Scott, L., Vadakkan, T. J., Larina, I. V., et al. (2015) · PLOS ONE · doi:10.1371/journal.pone.0131643 · Cited by 56 · see citing works

Gellan gum microgel-reinforced cell-laden gelatin hydrogels

Shin, H., Olsen, B. D., & Khademhosseini, A. (2013) · Journal of Materials Chemistry B · doi:10.1039/c3tb20984a · Cited by 59 · see citing works

Bioinspired double network hydrogels: from covalent double network hydrogels via hybrid double network hydrogels to physical double network hydrogels

Xu, X., Jerca, V. V., & Hoogenboom, R. (2020) · Materials Horizons · doi:10.1039/d0mh01514h · Cited by 536 · see citing works

Advanced Hydrogel Structures

Majcher, M. J., & Hoare, T. R. (2019) · Polymers and polymeric composites · doi:10.1007/978-3-319-95990-0_16 · Cited by 3 · see citing works

Advanced Hydrogel Structures

Majcher, M. J., & Hoare, T. R. (2018) · Polymers and polymeric composites · doi:10.1007/978-3-319-92066-5_16-1 · Cited by 3 · see citing works

Hydrogels, DNA, and RNA polypeptides for the preparation of biomaterials

Korah, L. V., Anilkumar, G. N., & Thomas, S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-08-102194-1.00005-0 · Cited by 20 · see citing works