The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The future of biologic coatings for orthopaedic implants
Open accessAbstract
Implants are widely used for othopaedic applications such as fixing fractures, repairing nonunions, obtaining a joint arthrodesis, total joint arthroplasty, spinal reconstruction, and soft tissue anchorage. Previously, orthopaedic implants were designed simply as mechanical devices; the biological aspects of the implant were a byproduct of stable internal/external fixation of the device to the surrounding bone or soft tissue. More recently, biologic coatings have been incorporated into orthopaedic implants in order to modulate the surrounding biological environment. This opinion article reviews current and potential future use of biologic coatings for orthopaedic implants to facilitate osseointegration and mitigate possible adverse tissue responses including the foreign body reaction and implant infection. While many of these coatings are still in the preclinical testing stage, bioengineers, material scientists and surgeons continue to explore surface coatings as a means of improving clinical outcome of patients undergoing orthopaedic surgery.
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Citations
Cites
Foreign body reaction to biomaterials
Anderson, J. M., Rodriguez, A., & Chang, D. T. (2008) · Seminars in Immunology · doi:10.1016/j.smim.2007.11.004 · Cited by 5,138 · cited 1×
“Insertion of an implant of any type within the body including bone evokes an inflammatory and (usually) limited foreign body reaction [56].”
Background
Cited by
Liu, X., Liu, J., Lin, S., & Zhao, X. (2020) · Materials Today · doi:10.1016/j.mattod.2019.12.026 · Cited by 1,023
Fernandes, H. R., Gaddam, A., Rebelo, A., Brazete, D., Stan, G. E., & Ferreira, J. M. F. (2018) · Materials · doi:10.3390/ma11122530 · Cited by 397
The Influence of Surface Modification on Bacterial Adhesion to Titanium-Based Substrates
Lorenzetti, M., Dogša, I., Stošicki, T., Stopar, D., Kalin, M., Kobe, S., & Novak, S. (2015) · ACS Applied Materials & Interfaces · doi:10.1021/am507148n · Cited by 365
Current status and prospects of metal-organic frameworks for bone therapy and bone repair
Li, M., Yin, S., Lin, M., Chen, X., Pan, Y., Peng, Y., Sun, J., Kumar, A., & Liu, J. (2022) · Journal of Materials Chemistry B · doi:10.1039/d2tb00742h · Cited by 156
Chen, J., Zhang, X., Huang, C., Cai, H., Hu, S., Wan, Q., Pei, X., & Wang, J. (2017) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.35960 · Cited by 150
Metadata
- Authors
- Goodman, S. B., Yao, Z., Keeney, M., & Yang, F.
- Venue
- Biomaterials
- Publisher
- Elsevier BV
- Published
- 2013-04
- Volume
- 34
- Issue
- 13
- Pages
- 3174-3183
- ISSN
- 0142-9612 (ISSN-L)
- OpenAlex
- W2128672939
- Cited by
- 779
- References
- 1
- FWCI
- 35.25
- Type
- journal article
- Language
- en
- Open access
- green
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- Goodman, S. B., Yao, Z., Keeney, M., & Yang, F. (2013). The future of biologic coatings for orthopaedic implants. Biomaterials. https://doi.org/10.1016/j.biomaterials.2013.01.074
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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