The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Silk based bioinks for soft tissue reconstruction using 3-dimensional (3D) printing with in vitro and in vivo assessments
Open accessAbstract
In the field of soft tissue reconstruction, custom implants could address the need for materials that can fill complex geometries. Our aim was to develop a material system with optimal rheology for material extrusion, that can be processed in physiological and non-toxic conditions and provide structural support for soft tissue reconstruction. To meet this need we developed silk based bioinks using gelatin as a bulking agent and glycerol as a non-toxic additive to induce physical crosslinking. We developed these inks optimizing printing efficacy and resolution for patient-specific geometries that can be used for soft tissue reconstruction. We demonstrated in vitro that the material was stable under physiological conditions and could be tuned to match soft tissue mechanical properties. We demonstrated in vivo that the material was biocompatible and could be tuned to maintain shape and volume up to three months while promoting cellular infiltration and tissue integration.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Matrix elasticity directs stem cell lineage specification
Engler, A. J., Sen, S., Sweeney, H. L., & Discher, D. E. (2006) · Cell · doi:10.1016/j.cell.2006.06.044 · Cited by 13,915
Direct-write bioprinting of cell-laden methacrylated gelatin hydrogels
Bertassoni, L. E., Cardoso, J. C., Manoharan, V., Cristino, A. L., Bhise, N. S., Araujo, W. A., Zorlutuna, P., Vrana, N. E., Ghaemmaghami, A. M., Dokmeci, M. R., et al. (2014) · Biofabrication · doi:10.1088/1758-5082/6/2/024105 · Cited by 642
Mauney, J. R., Nguyen, T., Gillen, K., Kirker-Head, C., Gimble, J. M., & Kaplan, D. L. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.08.017 · Cited by 373
Self-citationBiomimetic 3D tissue printing for soft tissue regeneration
Pati, F., Ha, D.-H., Jang, J., Han, H. H., Rhie, J.-W., & Cho, D.-W. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.05.043 · Cited by 368
Cited by
Hydrogel scaffolds for tissue engineering: the importance of polymer choice
Spicer, C. D. (2020) · Polymer Chemistry · doi:10.1039/c9py01021a · Cited by 527
Natural Hydrogel-Based Bio-Inks for 3D Bioprinting in Tissue Engineering: A Review
Fatimi, A., Okoro, O. V., Podstawczyk, D., Siminska-Stanny, J., & Shavandi, A. (2022) · Gels · doi:10.3390/gels8030179 · Cited by 276
3D printing to innovate biopolymer materials for demanding applications: A review
Li, N., Qiao, D., Zhao, S., Lin, Q., Zhang, B., & Xie, F. (2021) · Materials Today Chemistry · doi:10.1016/j.mtchem.2021.100459 · Cited by 142
A decade of progress in liver regenerative medicine
Zhang, J., Zhao, X., Liang, L., Li, J., Demirci, U., & Wang, S. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2017.11.027 · Cited by 111
In situ 3D bioprinting: a promising technique in advanced biofabrication strategies
Mahmoudi, Z., Sedighi, M., Jafari, A., Naghieh, S., Stefanek, E., Akbari, M., & Savoji, H. (2023) · Bioprinting · doi:10.1016/j.bprint.2023.e00260 · Cited by 38
Metadata
- Authors
- Rodriguez, M. J., Brown, J., Giordano, J., Lin, S. J., Omenetto, F. G., & Kaplan, D. L.
- Venue
- Biomaterials
- Publisher
- Elsevier BV
- Published
- 2017-02
- Volume
- 117
- Pages
- 105-115
- ISSN
- 0142-9612 (ISSN-L)
- OpenAlex
- W2552389473
- Cited by
- 220
- References
- 4
- FWCI
- 11.10
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Silk based bioinks for soft tissue reconstruction using 3-dimensional (3D) printing with in vitro and in vivo assessments. https://app.cochat.ai/papers/10.1016/j.biomaterials.2016.11.046
- The paper
- Rodriguez, M. J., Brown, J., Giordano, J., Lin, S. J., Omenetto, F. G., & Kaplan, D. L. (2017). Silk based bioinks for soft tissue reconstruction using 3-dimensional (3D) printing with in vitro and in vivo assessments. Biomaterials. https://doi.org/10.1016/j.biomaterials.2016.11.046
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
