Chlorogenic acid (CGA): A pharmacological review and call for further research

Flavonoids: an overview

Panche, A. N., Diwan, A. D., & Chandra, S. (2016) · Journal of Nutritional Science · doi:10.1017/jns.2016.41 · Cited by 5,953

Increased oxidative stress in obesity and its impact on metabolic syndrome

Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., & Shimomura, I. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21625 · Cited by 5,508

Systems biology: a brief overview

Kitano, H. (2002) · Science · doi:10.1126/science.1069492 · Cited by 4,265

Chronic Inflammation in Obesity and the Metabolic Syndrome

Monteiro, R., & Azevedo, I. (2010) · Mediators of Inflammation · doi:10.1155/2010/289645 · Cited by 1,186

Antimicrobial properties of phenolic compounds from berries

Puupponen‐Pimiä, R., Nohynek, L. J., Meier, C., Kähkönen, M., Heinonen, M., Hopia, A., & Oksman‐Caldentey, K. (2001) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2001.01271.x · Cited by 1,055

Chlorogenic acid exhibits anti-obesity property and improves lipid metabolism in high-fat diet-induced-obese mice

Cho, A.-S., Jeon, S.-M., Kim, M., Yeo, J., Seo, K., Choi, M., & Lee, M. (2010) · Food and Chemical Toxicology · doi:10.1016/j.fct.2010.01.003 · Cited by 787

The potential effects of chlorogenic acid, the main phenolic components in coffee, on health: a comprehensive review of the literature

Tajik, N., Tajik, M., Mack, I., & Enck, P. (2017) · European Journal of Nutrition · doi:10.1007/s00394-017-1379-1 · Cited by 730

Chlorogenic Acid: Recent Advances on Its Dual Role as a Food Additive and a Nutraceutical against Metabolic Syndrome

Santana‐Gálvez, J., Cisneros‐Zevallos, L., & Jacobo‐Velázquez, D. A. (2017) · Molecules · doi:10.3390/molecules22030358 · Cited by 725

Roles of Chlorogenic Acid on Regulating Glucose and Lipids Metabolism: A Review

Meng, S., Cao, J., Feng, Q., Peng, J., & Hu, Y. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/801457 · Cited by 619

Benzoic and Cinnamic Acid Derivatives as Antioxidants: Structure−Activity Relation

Natella, F., Nardini, M., Felice, M. D., & Scaccini, C. (1999) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf980737w · Cited by 606

Recovery of chlorogenic acid from haskap leaves (Lonicera caerulea) using aqueous two-phase extraction

Linna, X., Chong, K. Y., Stefanova, R., Hui, J. P. M., Zhang, J., & Brooks, M. S. (2021) · Biomass Conversion and Biorefinery · doi:10.1007/s13399-021-01524-8 · Cited by 15

3,5-Dicaffeoylquinic Acid Lowers 3T3-L1 Mitotic Clonal Expansion and Adipocyte Differentiation by Enhancing Heme Oxygenase-1 Expression

Raineri, A., Campagnari, R., Toso, R. D., Copetti, S., Gomez‐Lira, M., & Menegazzi, M. (2021) · Molecules · doi:10.3390/molecules26165027 · Cited by 14

In Vitro Free Radical Scavenging Properties and Anti‐Inflammatory Activity of Ilex paraguariensis (Maté) and the Ability of Its Major Chemical Markers to Inhibit the Production of Proinflammatory Mediators

Farias, I. V., Fratoni, E., Theindl, L. C., de Campos, Á. M., Dalmarco, E. M., & Reginatto, F. H. (2021) · Mediators of Inflammation · doi:10.1155/2021/7688153 · Cited by 17

Omnifarious fruit polyphenols: an omnipotent strategy to prevent and intervene diabetes and related complication?

Chen, Y., Qie, X., Quan, W., Zeng, M., Qin, F., Chen, J., Adhikari, B., & He, Z. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.2000932 · Cited by 16

Protective effects of chlorogenic acid on inflammatory responses induced by Staphylococcus aureus and milk protein synthesis in bovine mammary epithelial cells

Ji, Q., Zhang, M., Wang, Y., Chen, Y., Wang, L., Lu, X., Bai, L., Wang, M., Bao, L., Hao, H., et al. (2022) · Microbial Pathogenesis · doi:10.1016/j.micpath.2022.105726 · Cited by 14

Assessment of flavonoids and phenolic compound accumulation in invasive Solidago canadensis L. in Slovakia

Shelepova, O. V., Vinogradova, Y. K., Vergun, O. M., Grygorieva, O., & Brindza, J. (2020) · Potravinarstvo Slovak Journal of Food Sciences · doi:10.5219/1378 · Cited by 14

Phytochemical analysis and versatile in vitro evaluation of antimicrobial, cytotoxic and enzyme inhibition potential of different extracts of traditionally used Aquilegia pubiflora Wall. Ex Royle

Jan, H., Usman, H., Shah, M., Zaman, G., Mushtaq, S., Drouet, S., Hano, C., & Abbasi, B. H. (2021) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-021-03333-y · Cited by 14

An efficient approach to probe the bioactive transdermal components of traditional Chinese herbal patches by UHPLC-MS: Gutong patch as a case

Ma, C., Sheng, N., Shi, G., Zhang, J., & Zhang, T. (2021) · Phytomedicine · doi:10.1016/j.phymed.2021.153776 · Cited by 13

Characterization of Fruit Development, Antioxidant Capacity, and Potential Vasoprotective Action of Peumo (Cryptocarya alba), a Native Fruit of Chile

Valdenegro, M., Bernales, M., Knox, M., Vinet, R., Caballero, E., Ayala-Raso, A., Kučerová, D., Kumar, R., Viktorová, J., Ruml, T., et al. (2021) · Antioxidants · doi:10.3390/antiox10121997 · Cited by 13

Extract of Wheatgrass and Aronia Mixture Ameliorates Atopic Dermatitis-Related Symptoms by Suppressing Inflammatory Response and Oxidative Stress In Vitro and In Vivo

Lee, J., Lim, J.-Y., Jeon, Y., Yun, D.-H., Lee, Y., & Kim, D. (2022) · Antioxidants · doi:10.3390/antiox12010027 · Cited by 13

Effect of Common Cooking and Drying Methods on Phytochemical and Antioxidant Properties of Corchorus olitorius Identified Using Liquid Chromatography-Mass Spectrometry (LC-MS)

Ncube, B., Dlamini, B. C., & Beswa, D. (2022) · Molecules · doi:10.3390/molecules27249052 · Cited by 13

Anti-Inflammatory Activity of Chlorogenic Acid on Macrophages: A Simplified Simulation of Pharmacokinetics Following Ingestion Using a Windup Syringe Pump

Cao, L., Han, W., Lee, S. G., & Shin, J. H. (2023) · Applied Sciences · doi:10.3390/app13010627 · Cited by 13

Diosgenin content, phenolic acids, and antioxidant activity of different parts of Iranian Tribulus terrestris L.

Zahedi, R., Eghlima, G., Mirjalili, M. H., Aliahmadi, A., & Esmaeili, G. (2023) · Genetic Resources and Crop Evolution · doi:10.1007/s10722-023-01760-z · Cited by 13

Lonicera japonica protects Pelodiscus sinensis by inhibiting the biofilm formation of Aeromonas hydrophila

Huo, L.-C., Liu, N., Wang, C.-J., Luo, Y., & Liu, J. (2024) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-023-12910-9 · Cited by 13

Phytonutritional Composition and Antioxidant Properties of Southern African, Purple-Fleshed Sweet Potato (Ipomoea batatas (L.) Lam.) Storage Roots

Ngcobo, A., Mianda, S. M., Seke, F., LAURIE, S. M., & Sivakumar, D. (2024) · Antioxidants · doi:10.3390/antiox13030338 · Cited by 13

Chlorogenic Acid as a Potential Therapeutic Agent for Cholangiocarcinoma

Liang, J.-B., Wen, T., Zhang, X., & Luo, X. (2024) · Pharmaceuticals · doi:10.3390/ph17060794 · Cited by 13

Medicinal and culinary importance of edible flowers of indian origin: an in-depth review

Gupta, A., Sharma, S., Rajput, D., & Patil, U. K. (2024) · Discover Food · doi:10.1007/s44187-024-00220-6 · Cited by 14

Traditional Chinese medicine-based drug delivery systems for anti-tumor therapies

Ling, Y. A. N. G., Wang, Y., Ye, X., Liu, Q., Qu, D., & Chen, Y. (2024) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(24)60746-6 · Cited by 13

The Role of Extracts of Edible Parts and Production Wastes of Globe Artichoke (Cynara cardunculus L. var. scolymus (L.)) in Counteracting Oxidative Stress

Masci, V. L., Mezzani, I., Alicandri, E., Tomassi, W., Paolacci, A. R., Covino, S., Vinciguerra, V., Catalani, E., Cervia, D., Ciaffi, M., et al. (2025) · Antioxidants · doi:10.3390/antiox14010116 · Cited by 13

Chlorogenic acid improves SPS-induced PTSD-like behaviors in rats by regulating the crosstalk between Nrf2 and NF-κB signaling pathway

Tang, C. L., Gao, J., Li, S., Cheng, Y.-F., Peng, Y.-Y., Ding, Y., Yang, H., Ma, X.-M., Wang, H., Long, Z., et al. (2025) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2025.02.034 · Cited by 14

A strategy for quality evaluation of salt-treated Apocyni Veneti Folium and discovery of efficacy-associated markers by fingerprint-activity relationship modeling

Chen, C., Chen, J., Shi, J., Chen, S., Zhao, H., Yan, Y., Jiang, Y., Gu, L., Chen, F., & Liu, X. (2019) · Scientific Reports · doi:10.1038/s41598-019-52963-3 · Cited by 13

A Potential Polymeric Nanogel System for Effective Delivery of Chlorogenic Acid to Target Collagen-Induced Arthritis

Ma, Y., Song, Y., Ma, F., & Chen, G. (2019) · Journal of Inorganic and Organometallic Polymers and Materials · doi:10.1007/s10904-019-01421-8 · Cited by 13

Ethylene Induction of Non-Enzymatic Metabolic Antioxidants in Matricaria chamomilla

Petruľová, V., Vilková, M., Dučaiová, Z., Sajko, M., & Repčák, M. (2020) · Molecules · doi:10.3390/molecules25235720 · Cited by 13

Cytotoxic Role of Chlorogenic Acid on Oral Squamous Cell Carcinoma Cell Line

Sharma, G., Kamboj, M., Narwal, A., Bhardwaj, R., & Yadav, P. (2021) · Indian Journal of Otolaryngology and Head & Neck Surgery · doi:10.1007/s12070-021-02395-1 · Cited by 13

Neuroprotective effect of green and roasted coffee bean extracts on cerebral ischemia-induced injury in rats

Rizk, S., Taha, H., Moneim, A. E. A., & Amin, H. K. (2021) · Metabolic Brain Disease · doi:10.1007/s11011-021-00769-6 · Cited by 13

Phytochemical Study of Eryngium cymosum F. Delaroche and the Inhibitory Capacity of Its Main Compounds on Two Glucose-Producing Pathway Enzymes

Romo‐Pérez, A., Escandón–Rivera, S., Miranda, L. D., & Adolfo Andrade-cetto, A. (2022) · Plants · doi:10.3390/plants11070992 · Cited by 13

Modified Qing’e Formula protects against UV-induced skin oxidative damage via the activation of Nrf2/ARE defensive pathway

Zhu, S., Qin, W., Liu, T., Liu, T., Ma, H., Hu, C., Yue, X., Yan, Y., Lv, Y., Wang, Z., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.976473 · Cited by 13

Physicochemical properties and phytochemical components of white mulberry (Morus alba L.) fruits with different density at harvest

Wang, K., Ren, W., Jia, X., Xing, Y., Wang, Y., Wang, J., & Xu, H. (2022) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2022.105113 · Cited by 13

Estrogen Receptor-Mediated Transcriptional Activities of Spent Coffee Grounds and Spent Coffee Grounds Compost, and Their Phenolic Acid Constituents

An, B. H., Jeong, H., Kim, J.-H., Park, S., Jeong, J.-H., Kim, J. M., & Chang, M. (2019) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b02452 · Cited by 13

Inhibitory effects of polyphenols and their colonic metabolites on CYP2D6 enzyme using two different substrates

Fliszár-Nyúl, E., Mohos, V., Csepregi, R. K., Mladěnka, P., & Poór, M. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110732 · Cited by 13

Inhibition of Human Cathepsins B and L by Caffeic Acid and Its Derivatives

Ulčakar, L., & Novinec, M. (2020) · Biomolecules · doi:10.3390/biom11010031 · Cited by 13

Seasonal Variations of the Nutritive Value and Phytotherapeutic Potential of Cladium mariscus L. (Pohl.) Targeting Ruminant’s Production

Oliveira, M., Rodrigues, M. J., Neng, N. R., Nogueira, J. M. F., Bessa, R. J. B., & Custódio, L. M. B. (2021) · Plants · doi:10.3390/plants10030556 · Cited by 13

Exercise and Nutraceuticals: Eminent Approach for Diabetic Neuropathy

Upaganlawar, A., Kale, M. B., Bajaj, K. K., Umare, M., Wankhede, N. L., Taksande, B. G., & Umekar, M. J. (2021) · Current Molecular Pharmacology · doi:10.2174/1874467214666210629123010 · Cited by 13

Bioactive Substances of Potato Juice Reveal Synergy in Cytotoxic Activity against Cancer Cells of Digestive System Studied In Vitro

Kowalczewski, P. Ł., Olejnik, A. M., Wieczorek, M. N., Zembrzuska, J., Kowalska, K., Lewandowicz, J., & Lewandowicz, G. (2022) · Nutrients · doi:10.3390/nu15010114 · Cited by 13

Anti-adipogenic and antioxidant activities of spent coffee grounds extracts: impacts of chlorogenic acid and caffeic acid

Kim, G., Jeong, H. J., Kim, S., & Han, G. D. (2025) · Food Science and Biotechnology · doi:10.1007/s10068-025-01886-z · Cited by 11

Laser-induced UiO-66-derived ZrO2-ZrC-graphene sensor for sensitive detection of chlorogenic acid in food samples

Geng, J., Lv, Y., Huang, Z., Lin, F., Neha, Mohan, B., & Sun, W. (2026) · Microchemical Journal · doi:10.1016/j.microc.2026.117108 · Cited by 12

Protective effects of chlorogenic acid against ionizing radiation-induced testicular toxicity

Abedpour, N., Zeinali, A., Karimipour, M., Pourheidar, B., Farjah, G. H., Abak, A., & Shoorei, H. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e10798 · Cited by 12

Trait Mapping of Phenolic Acids in an Interspecific (Vaccinium corymbosum var. caesariense × V. darrowii) Diploid Blueberry Population

Herniter, I. A., Kim, Y., Wang, Y., Havill, J. S., Johnson‐Cicalese, J. M., Muehlbauer, G. J., Iorizzo, M., & Vorsa, N. (2023) · Plants · doi:10.3390/plants12061346 · Cited by 12

Phytoconstituent Profiles Associated with Relevant Antioxidant Potential and Variable Nutritive Effects of the Olive, Sweet Almond, and Black Mulberry Gemmotherapy Extracts

Alaya, A., Mihok, E. A., Pecsenye, B., Jolji, M., Kertész, A., Bársony, P., Vígh, S., Cziáky, Z., Máthé, A. B., BURTESCU, R. F., et al. (2023) · Antioxidants · doi:10.3390/antiox12091717 · Cited by 14

Targeting the NLRP3 inflammasome for the treatment of hypertensive target organ damage: Role of natural products and formulations

Liao, X., Han, Y., Shen, C., Liu, J., & Wang, Y. (2023) · Phytotherapy Research · doi:10.1002/ptr.8009 · Cited by 12

Functional properties of a kefir-based probiotic dairy product enriched with red prickly pear (Opuntia dillenii) powder

Taheur, F. B., Chahbani, A., Mansour, C., Mokni, A., Amira, A. B., Jridi, M., Fakhfakh, N., & Zouari, N. (2023) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-023-02136-8 · Cited by 12

Modulation of apoptosis and Inflammasome activation in chondrocytes: co-regulatory role of Chlorogenic acid

Kulyar, M. F., Mo, Q., Yao, W., Li, Y., Nawaz, S., Loon, K. S., Ahmed, A. E., Alsaegh, A., Syaad, K. M. A., Akhtar, M. F., et al. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-023-01377-w · Cited by 12

The recent advance and prospect of natural source compounds for the treatment of heart failure

Chen, X.-J., Liu, S., Li, S., Feng, J.-K., Hu, Y. C., Cheng, X., Hou, C., Xu, Y., Hu, M., Ling, F., et al. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e27110 · Cited by 17

Chlorogenic Acid Plays an Important Role in Improving the Growth and Antioxidant Status and Weakening the Inflammatory Response of Largemouth Bass (Micropterus salmoides)

Xia, Z., Mi, H., Ren, M., Huang, D., Aboseif, A. M., Liang, H., & Zhang, L. (2024) · Animals · doi:10.3390/ani14192871 · Cited by 12

The emerging role of honeysuckle flower in inflammatory bowel disease

Muro, P., Jing, C., Zhao, Z., Jin, T., & Mao, F. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1525675 · Cited by 13

A Cecropia peltata ethanolic extract reduces insulin resistance and hepatic steatosis in rats fed a high-fat diet

Andrea, D.-A., Cu-Cañetas, T. E., Ávila-Nava, A., Sansores-España, D., Acevedo‐Fernández, J. J., Peraza, V. M. S., Chel‐Guerrero, L., & Torre-Villalvazo, I. (2020) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2020.113087 · Cited by 12

Changes in Phenolics and Fatty Acids Composition and Related Gene Expression during the Development from Seed to Leaves of Three Cultivated Cardoon Genotypes

Graziani, G., Docimo, T., Palma, M. D., Sparvoli, F., Izzo, L., Tucci, M., & Ritieni, A. (2020) · Antioxidants · doi:10.3390/antiox9111096 · Cited by 12

Cytotoxicity, genotoxicity, and gene expression changes induced by methanolic extract of Moringa stenopetala leaf with LC-qTOF-MS metabolic profile

El‐Mekkawy, S., Hassan, A. Z., Abdelhafez, M. A., Mahmoud, K. M., Mahrous, K. F., Meselhy, M. R., Sendker, J., & Abdel-Sattar, E. A. (2021) · Toxicon · doi:10.1016/j.toxicon.2021.09.025 · Cited by 14

Phenolic acids and flavonoids‐rich Glechoma hederacea L. (Lamiaceae) water extract against H 2 O 2 ‐induced apoptosis in PC12 cells

Chao, W., Chan, W. C., Ma, H., & Chou, S. (2021) · Journal of Food Biochemistry · doi:10.1111/jfbc.14032 · Cited by 12

Bioassay-guided preparation of antioxidant, anti-inflammatory active fraction from crabapples (Malus prunifolia (Willd.) Borkh.)

Abuduaini, M., Li, J., Ruan, J. H., Zhao, Y. X., Maiwulanjiang, M., & Aisa, H. A. (2022) · Food Chemistry · doi:10.1016/j.foodchem.2022.135091 · Cited by 12

Antioxidant and anti-inflammatory potential of rhizome aqueous extract of sea holly (Eryngium maritimum L.) on Jurkat cells

Cortés‐Fernández, I., Sureda, A., Adrover, M., Caprioli, G., Maggi, F., Gil, L., & Capó, X. (2023) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2022.116120 · Cited by 12

Understanding pathophysiology of GNE myopathy and current progress towards drug development

Mashangva, F., Singh, S., Oswalia, J., & Arya, R. (2024) · Journal of Biosciences · doi:10.1007/s12038-023-00414-7 · Cited by 12

Inclusion complex of β-cyclodextrin with coffee chlorogenic acid: new insights from a combined crystallographic and theoretical study

Aree, T. (2018) · Acta Crystallographica Section C Structural Chemistry · doi:10.1107/s2053229618016741 · Cited by 12

Leonurus sibiricus root extracts decrease airway remodeling markers expression in fibroblasts

Wieczfińska, J., Sitarek, P., Kowalczyk, T., & Pawliczak, R. (2020) · Clinical & Experimental Immunology · doi:10.1111/cei.13481 · Cited by 12

The Design of Three-Zone Simulated Moving Bed Process for the Separation of Chlorogenic and Gallic Acids Extracted from Spent Coffee Grounds

Nakkong, K., Tangpromphan, P., & Jaree, A. (2020) · Waste and Biomass Valorization · doi:10.1007/s12649-020-01160-9 · Cited by 12

Biological Activity and NMR-Fingerprinting of Balkan Endemic Species Stachys thracica Davidov

Mantovska, D. I., Zhiponova, M., Georgiev, M. I., Alipieva, K. I., Tsacheva, I., Simova, S., & Yordanova, Z. P. (2022) · Metabolites · doi:10.3390/metabo12030251 · Cited by 12

Polish Achievements in Bioactive Compound Production From In Vitro Plant Cultures

Pietrosiuk, A., Budzianowska, A., Budzianowski, J., Ekiert, H., Jeziorek, M., Kawiak, A., Kikowska, M. A., Krauze‐Baranowska, M., Królicka, A., Kuźma, Ł., et al. (2022) · Acta Societatis Botanicorum Poloniae · doi:10.5586/asbp.9110 · Cited by 12

The Mechanisms of Neochlorogenic Acid (3-Caffeoylquinic Acid) in Improving glucose and Lipid Metabolism in Rats with Insulin Resistance Induced by A High Fat-High Fructose Diet

Singdam, P., Naowaboot, J., Senggunprai, L., Boonloh, K., Hipkaeo, W., & Pannangpetch, P. (2023) · Trends in Sciences · doi:10.48048/tis.2023.6455 · Cited by 11

Identification of HQT gene family and their potential function in CGA synthesis and abiotic stresses tolerance in vegetable sweet potato

Medison, M. B., Pan, R., Peng, Y., Medison, R. G., Shalmani, A., Yang, X., & Zhang, W. (2023) · Physiology and Molecular Biology of Plants · doi:10.1007/s12298-023-01299-4 · Cited by 11

Red and golden tomato administration improves fat diet-induced hepatic steatosis in rats by modulating HNF4α, Lepr, and GK expression

Pipitone, R. M., Zito, R., Gambino, G., Maria, G. D., Javed, A., Lupo, G., Giglia, G., Sardo, P., Ferraro, G., Rappa, F., et al. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1221013 · Cited by 11

Effects Of Exercise Training And Chlorogenic Acid Supplementation On Hepatic Lipid Metabolism In Prediabetes Mice

Shirkhani, S., Marandi, S. M., Nasr‐Esfahani, M. H., & Kim, S. K. (2023) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2022.0265 · Cited by 11

Combined non-targeted metabolomic and transcriptomic analysis explains the biosynthetic pathway and differential accumulation of chlorogenic acid in the Liriodendron petal

Hu, L., Yu, L., Weng, Y., Qu, H., Yang, D., Lu, Y., Wang, P., Shi, J., Hao, Z., & Chen, J. (2024) · Scientia Horticulturae · doi:10.1016/j.scienta.2023.112791 · Cited by 11

Chlorogenic acid regulates the expression of protein phosphatase 2A subunit B in the cerebral cortex of a rat stroke model and glutamate-exposed neurons

Kang, J.-B., Son, H.-K., Park, D.-J., Jin, Y. B., & Koh, P. (2024) · Laboratory Animal Research · doi:10.1186/s42826-024-00196-5 · Cited by 11

The Effects of Sunflower and Maize Crop Residue Extracts as a New Ingredient on the Quality Properties of Pork Liver Pâtés

Glišić, M., Bošković, M., Čobanović, N., Starčević, M., Samardžić, S., Veličković, I., & Maksimovic, Z. A. (2024) · Foods · doi:10.3390/foods13050788 · Cited by 11

Unveiling the phytochemical profiles, selective bioactivity potential, and molecular docking study of bioactive compounds with target proteins using optimized bark extracts of Grewia asiatica L.

Begum, S. N., Ray, A. S., Hazra, S., De, S., & Rahaman, C. H. (2024) · Kuwait Journal of Science · doi:10.1016/j.kjs.2024.100230 · Cited by 12

Protective effect of chlorogenic acid on liver injury in heat‐stressed meat rabbits

Ji, R., Chen, J., Xu, J., Zhang, L., Liu, L., & Li, F. (2024) · Journal of Animal Physiology and Animal Nutrition · doi:10.1111/jpn.13966 · Cited by 11

Optimization of polyphenol extraction, phenolic profile by LC-ESI-MS/MS, antioxidant, anti-enzymatic, and cytotoxic activities of Physalis acutifolia

Derbak, L., Bendıf, H., Ayad, R., Bensouıcı, C., Yıldız, İ., Demirtaş, İ., Rebbas, K., Plavan, G. I., Hamadi, N. B., Abu-Elsaoud, A. M., et al. (2024) · Open Chemistry · doi:10.1515/chem-2024-0040 · Cited by 11

Chlorogenic acid/carboxymethyl chitosan nanoparticle-assisted biomultifunctional hyaluronic acid-based hydrogel scaffolds for burn skin repair

Zhang, R., Li, H., Zhang, W., Zhang, T., Chen, X., Lu, W., Zhang, B., Wang, Y., & Guo, Y. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.133528 · Cited by 12

Algerian Prickly Pear Seed By-Products: Fatty Acids Composition, Antioxidant, Enzyme Inhibitory Activities towards Tyrosinase, Urease, α-Amylase, and Cholinesterase, along with the Ability to Protect from Thermal Protein Denaturation

Chafaa, N., Mosbah, C., Khattabi, L., Malaoui, K., Zahnit, W., Smaali, M. E. A., Houri, F., Medfouni, Y., Al‐Anazi, K. M., & Ali, A. (2024) · Pharmaceuticals · doi:10.3390/ph17091145 · Cited by 11

Boosting Health Benefits in Vegetables: A Novel Ultraviolet B (UVB) Device for Rapid At-Home Enhancement of Phytochemicals and Bioactivity

Gastélum‐Estrada, A., Reza-Zaldívar, E. E., & Jacobo‐Velázquez, D. A. (2024) · Foods · doi:10.3390/foods13203311 · Cited by 11

Valorization of Elderberry Pomace using Emerging High-Pressure Technologies: Separation of Compounds with Different Polarities using Subcritical H2O, Supercritical CO2, and CO2/H2O/EtOH Mixture

Mutavski, Z., Nastić, N. M., Fernández, N., Živković, J., Šavikin, K., Vujisić, L. V., Veberič, R., Medič, A., & Vidović, S. S. (2024) · Food and Bioprocess Technology · doi:10.1007/s11947-024-03636-1 · Cited by 11

Comparative Analysis of Phytochemical and Functional Profiles of Arabica Coffee Leaves and Green Beans Across Different Cultivars

Jeon, Y.-A., Natraj, P., Kim, S., Moon, J., & Lee, Y. J. (2024) · Foods · doi:10.3390/foods13233744 · Cited by 14

Screening of Chemical Profile by LC–MS/MS and Assessment of Biological Properties of Achillea sintenisii Hub. Mor. From Turkey

Köksal, E., Altay, A., Altın, S., Alp, C., Ulutaş, Y., Şimşek, S., Karakuş, S., Akyüz, S., Aygül, İ., Akşit, H., et al. (2025) · Chemistry & Biodiversity · doi:10.1002/cbdv.202500026 · Cited by 11

Extraction of chlorogenic acid from Lonicera japonica Thunb. using deep eutectic solvents: Process optimization and mechanism exploration by the combination of experiment and molecular simulation

Fan, Z., Li, J., Zhou, J., Chen, Y., & Cui, Z. (2025) · Microchemical Journal · doi:10.1016/j.microc.2025.113280 · Cited by 11

Chlorogenic Acid Ameliorates Acetaminophen-Induced Liver Injury Through AMPK/mTOR/ULK1-Mediated Autophagy Activation

Yao, Y.-X., Yao, C.-H., Zhang, C.-Y., Peng, X.-Z., Dai, S., Yu, Y.-J., Li, Y.-Z., Zhang, S.-L., & Li, Y. (2025) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x2550020x · Cited by 11

Stability and degradation of chlorogenic acids in green and roasted coffee beans during long-term storage

Badmos, S., & Kuhnert, N. (2025) · Food Research International · doi:10.1016/j.foodres.2025.117031 · Cited by 11

Composition and antifungal effects of aqueous extracts ofCymbopogon citratus,Laurus nobilisandSantolina chamaecyparissuson the growth ofFusarium oxysporumf. sp.lentis

Aourach, M., Barbero, G. F., González-de-Peredo, A. V., Diakite, A., Boukari, M. E., & Essalmani, H. (2021) · Archives of Phytopathology and Plant Protection · doi:10.1080/03235408.2021.1922169 · Cited by 11

Efficacy of chlorogenic acid against ethylene glycol-induced renal stone model: The role of NFKB-RUNX2-AP1-OSTERIX signaling pathway

Hoseinynejad, K., Mard, S. A., Mansouri, Z., Lamoochi, Z., & Kazemzadeh, R. (2022) · Tissue and Cell · doi:10.1016/j.tice.2022.101960 · Cited by 11

Bioactive Yoghurt Containing Curcumin and Chlorogenic Acid Reduces Inflammation in Postmenopausal Women

Nasef, N. A., Thota, R. N., Mutukumira, A. N., Rutherfurd-Markwick, K. J., Dickens, M., Gopal, P. K., Singh, H., & Garg, M. L. (2022) · Nutrients · doi:10.3390/nu14214619 · Cited by 11

Repurposing of phyto-ligand molecules from the honey bee products for Alzheimer’s disease as novel inhibitors of BACE-1: small molecule bioinformatics strategies as amyloid-based therapy

Nisa, N., Rasmita, B., Arati, C., Uditraj, C., Siddhartha, R., Dinata, R., Bhanushree, B., Bidanchi, R. M., Manikandan, B., Saeed, A.-L., et al. (2023) · Environmental Science and Pollution Research · doi:10.1007/s11356-023-25943-4 · Cited by 11

Canadian Prairie Berries: Bioactive Compounds and Their Potential Health Benefits

Kodikara, C., Bandara, N., Netticadan, T., & Wijekoon, C. P. (2023) · Food Reviews International · doi:10.1080/87559129.2023.2273934 · Cited by 11

Current Research in Agricultural and Food Science Vol. 1

Mohammed, H. N., Beeram, E., Divya, B. J., Pallavi, C., DEMİR, H. A., Demir, B. B., Polley, T., Ghosh, U., Shiekuma, S., Ukeyima, M. T., et al. (2020) · Book Publisher International (a part of SCIENCEDOMAIN International) · doi:10.9734/bpi/crafs/v1 · Cited by 11

The influence of environmental variations on the phenolic compound profiles and antioxidant activity of two medicinal Patagonian valerians (Valeriana carnosa Sm. and V. clarionifolia Phil.)

Nagahama, N., Estación Experimental Agroforestal Esquel, I. N. D. T. A. (., Gastaldi, B., Clifford, M. N., Manifesto, M. M., Fortunato, R. H., (CONICET), C. N. D. I. C. Y. T., Laboratorio de Investigación de Plantas Aromáticas y Medicinales Nativas (LIPAM), F., & Instituto de Recursos Biológicos, C. I. (2020) · AIMS Agriculture and Food · doi:10.3934/agrfood.2021007 · Cited by 11

Analysis of Antioxidant Constituents from Ilex rotunda and Evaluation of Their Blood–Brain Barrier Permeability

Kim, C., Ahn, J., Yu, J., Le, D. D., Han, S., & Lee, M. (2022) · Antioxidants · doi:10.3390/antiox11101989 · Cited by 11

Yinzhihuang oral liquid protects against non-alcoholic steatohepatitis via modulation of the gut-liver axis in mice

Li, S., Chen, F., Zou, Y., Ning, L., Zhang, G., Zhang, S., & Yao, Q. (2022) · Annals of Translational Medicine · doi:10.21037/atm-21-4809 · Cited by 10

Chlorogenic acid reduces inflammation in murine model of acute pancreatitis

Tarasiuk, A., Bulak, K., Talar, M., & Fichna, J. (2021) · Pharmacological Reports · doi:10.1007/s43440-021-00320-5 · Cited by 10

Towards Bioprospection of Commercial Materials of Mentha spicata L. Using a Combined Strategy of Metabolomics and Biological Activity Analyses

Henao‐Rojas, J. C., Osorio, E., Isaza, S., Solarte, I. A. M., Sierra, K., Zapata-Vahos, I. C., Peréz, J. F. B., Valencia, J. W. A., & Gallego, A. (2022) · Molecules · doi:10.3390/molecules27113559 · Cited by 12

Integrated metabolomic and transcriptomic analysis reveals variation in the metabolites and genes of Platycodon grandiflorus roots from different regions

Chang, A., Pei, W., Li, S., Wang, T., Song, H., Kang, T., & Zhang, H. (2022) · Phytochemical Analysis · doi:10.1002/pca.3153 · Cited by 10

A comprehensive review of non-alkaloidal metabolites from the subfamily Amaryllidoideae (Amaryllidaceae)

Ibrakaw, A. S., Akinfenwa, A. O., & Hussein, A. A. (2023) · Open Chemistry · doi:10.1515/chem-2022-0252 · Cited by 10

Restoring Ampicillin Sensitivity in Multidrug-Resistant Escherichia coli Following Treatment in Combination with Coffee Pulp Extracts

Rawangkan, A., Yosboonruang, A., Kiddee, A., Siriphap, A., Pook-In, G., Praphasawat, R., Saokaew, S., & Duangjai, A. (2023) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2304.04051 · Cited by 10

Chlorogenic Acid Inhibits Ceramide Accumulation to Restrain Hepatic Glucagon Response

Xiao, N., Zhang, T., Han, M., Tian, D., Liu, J., Li, S., Yang, L., & Pan, G. (2023) · Nutrients · doi:10.3390/nu15143173 · Cited by 11

A pharmacokinetic study on twenty-one compounds in rat plasma by integrating UPLC-QQQ-MS/MS with GC-MS after oral administration of Suxiao Jiuxin pill

Shang, Y., Ge, M., Zhao, P., Wu, T., Wei, S., Zhou, H. W., Jiang, Y., Shang, D., Wang, J., Geng, T., et al. (2023) · Arabian Journal of Chemistry · doi:10.1016/j.arabjc.2023.105397 · Cited by 10

Deep eutectic solvents as efficient extractants of caffeoylquinic acids from Blumea aromatica: A comparative analysis of content and antioxidant potential

Dai, W., Dai, L., Chu, D., Pang, R., Deng, J., Wang, S., Li, J., Chen, H., & Zheng, X. (2023) · Arabian Journal of Chemistry · doi:10.1016/j.arabjc.2023.105596 · Cited by 10

Wounding stress enhances the anti-obesogenic, anti-inflammatory, and antioxidant properties of carrots (Daucus carota)

Reza-Zaldívar, E. E., Bojorquez-Rodríguez, E. M., & Jacobo‐Velázquez, D. A. (2024) · Journal of Agriculture and Food Research · doi:10.1016/j.jafr.2024.101155 · Cited by 11

Caffeoylquinic acids from Silphium perfoliatum L. show hepatoprotective effects on cholestatic mice by regulating enterohepatic circulation of bile acids

Zhang, G., Jia, W., Liu, L., Wang, L., Xu, J., Tao, J., Xu, M., Yue, M., Luo, H., Hai, P., et al. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.118870 · Cited by 12

N-butanol extract of Broussonetia papyrifera (L.) L′Hér. ex Vent root bark alleviates atopic dermatitis by targeting E3 ubiquitin ligase WWP1 to promote NLRP3 degradation

Zeng, C., Weng, L., Song, Y., Huang, Y., Xiang, W., Ye, Z., Yu, C., Lai, Z., Song, Y., Yang, H., et al. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117561 · Cited by 10

Bioactive compounds (LC-PDA-Qtof-ESI-MS and UPLC-PDA-FL) and in vitro inhibit α-amylase and α-glucosidase in leaves and fruit from different varieties of Ficus carica L.

Teruel‐Andreu, C., Cano‐Lamadrid, M., Hernández, F., & Wojdyło, A. (2024) · Food Chemistry · doi:10.1016/j.foodchem.2024.141977 · Cited by 10

Combination of Lycium barbarum polysaccharide and chlorogenic acid: Characterization of solution property, interaction, and regulatory function on typical gut Bacteroides and pathogens

Liang, L., Lin, L., & Zhao, M. (2025) · Food Chemistry · doi:10.1016/j.foodchem.2025.142779 · Cited by 10

A systematic review of Aspilia africana (Pers.) C.D. adams traditional medicinal uses, phytoconstituents, bioactivities, and toxicities

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CHLOROGENIC ACID: A PHARMACOLOGICALLY POTENT MOLECULE.

Maalik, A., Bukhari, S. M., Zaidi, A., Shah, K. H., & Khan, F. A. (2016) · PubMed · Cited by 41

A deeper insight into the pharmacological and biochemical effects of chlorogenic acid: a review article

Alenazi, A., Elkhoely, A. A., Kabel, A., & Eissa, A. A. (2026) · Journal of Advanced Pharmacy Research · doi:10.21608/aprh.2025.446825.1348

Roles of Chlorogenic Acid on Regulating Glucose and Lipids Metabolism: A Review

Meng, S., Cao, J., Feng, Q., Peng, J., & Hu, Y. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/801457 · Cited by 619

Chlorogenic Acid: A Dietary Phenolic Acid with Promising Pharmacotherapeutic Potential

Singh, A. K., Singla, R. K., & Pandey, A. K. (2022) · Current Medicinal Chemistry · doi:10.2174/0929867329666220816154634 · Cited by 118

Chlorogenic acid: A comprehensive review of the dietary sources, processing effects, bioavailability, beneficial properties, mechanisms of action, and future directions

Lu, H., Tian, Z., Cui, Y., Liu, Z., & Ma, X. (2020) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12620 · Cited by 476