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Cited by 566

The DOI matches its Crossref record; 141 of the 141 references it cites were found in a registry or an index.

Mesoporous silica nanoparticles for therapeutic/diagnostic applications

Open access
Jafari, Samira, Derakhshankhah, Hossein, Alaei, Loghman, Fattahi, Ali, Varnamkhasti, Behrang Shiri, Saboury, Ali Akbar·2019·Biomedicine & Pharmacotherapy

Abstract

Based on unique intrinsic properties of mesoporous silica nanoparticles (MSNs) such as high surface area, large pore size, good biocompatibility and biodegradability, stable aqueous dispersion, they have received much attention in the recent decades for their applications as a promising platform in the biomedicine field. These porous structures possess a pore size ranging from 2 to 50 nm which make them excellent candidates for various biomedical applications. Herein, at first we described the common approaches of cargo loading and release processes from MSNs. Then, the intracellular uptake, safety and cytotoxicity aspects of MSNs are discussed as well. This review also highlights the most recent advances in the biomedical applications of MSNs, including 1) MSNs-based carriers, 2) MSNs as bioimaging agents, 3) MSNs-based biosensors, 4) MSNs as therapeutic agents (photodynamic therapy), 5) MSN based quantum dots, 6) MSNs as platforms for upconverting nanoparticles, and 6) MSNs in tissue engineering.

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Crossref · 10.1016/j.biopha.2018.10.167

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Metadata

Authors
Jafari, S., Derakhshankhah, H., Alaei, L., Fattahi, A., Varnamkhasti, B. S., & Saboury, A. A.
Venue
Biomedicine & Pharmacotherapy
Publisher
Elsevier BV
Published
2019-01
Volume
109
Pages
1100-1111
ISSN
0753-3322 (ISSN-L)
OpenAlex
W2900125153
Cited by
566
References
141
FWCI
14.19
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Mesoporous silica nanoparticles for therapeutic/diagnostic applications. https://app.cochat.ai/papers/10.1016/j.biopha.2018.10.167
The paper
Jafari, S., Derakhshankhah, H., Alaei, L., Fattahi, A., Varnamkhasti, B. S., & Saboury, A. A. (2019). Mesoporous silica nanoparticles for therapeutic/diagnostic applications. Biomedicine & Pharmacotherapy. https://doi.org/10.1016/j.biopha.2018.10.167

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.